Assay ID | Title | Year | Journal | Article |
AID147491 | In vitro inhibitory activity against neuraminidase | 2003 | Journal of medicinal chemistry, Oct-09, Volume: 46, Issue:21
| Simple, intuitive calculations of free energy of binding for protein-ligand complexes. 2. Computational titration and pH effects in molecular models of neuraminidase-inhibitor complexes. |
AID488379 | Inhibition of Influenza A virus neuraminidase | 2010 | Bioorganic & medicinal chemistry, Jun-01, Volume: 18, Issue:11
| Analogs of zanamivir with modified C4-substituents as the inhibitors against the group-1 neuraminidases of influenza viruses. |
AID384920 | Inhibition of influenza virus neuraminidase | 2008 | European journal of medicinal chemistry, Mar, Volume: 43, Issue:3
| QSAR study of neuraminidase inhibitors based on heuristic method and radial basis function network. |
AID203527 | Compound was tested for the inhibition of influenza virus sialidase using 2'-(4-methylumbelliferyl)-N-acetylneuraminic acid substrate | 1996 | Journal of medicinal chemistry, Jan-19, Volume: 39, Issue:2
| A study of the active site of influenza virus sialidase: an approach to the rational design of novel anti-influenza drugs. |
AID729049 | Selectivity ratio of IC50 for human neuraminidase 1 to IC50 for human neuraminidase 2 | 2013 | Journal of medicinal chemistry, Apr-11, Volume: 56, Issue:7
| Identification of selective inhibitors for human neuraminidase isoenzymes using C4,C7-modified 2-deoxy-2,3-didehydro-N-acetylneuraminic acid (DANA) analogues. |
AID729055 | Inhibition of human neuraminidase 3 expressed in Escherichia coli using 4MU-NANA as substrate after 30 mins by fluorescence assay | 2013 | Journal of medicinal chemistry, Apr-11, Volume: 56, Issue:7
| Identification of selective inhibitors for human neuraminidase isoenzymes using C4,C7-modified 2-deoxy-2,3-didehydro-N-acetylneuraminic acid (DANA) analogues. |
AID488378 | Antiviral activity against Influenza A virus (A/Singapore/1/1957 (H2N2)) infected in MDCK cells assessed as inhibition of virus-induced plaque formation | 2010 | Bioorganic & medicinal chemistry, Jun-01, Volume: 18, Issue:11
| Analogs of zanamivir with modified C4-substituents as the inhibitors against the group-1 neuraminidases of influenza viruses. |
AID728984 | Selectivity ratio of IC50 for human neuraminidase 3 to IC50 for human neuraminidase 2 | 2013 | Journal of medicinal chemistry, Apr-11, Volume: 56, Issue:7
| Identification of selective inhibitors for human neuraminidase isoenzymes using C4,C7-modified 2-deoxy-2,3-didehydro-N-acetylneuraminic acid (DANA) analogues. |
AID729057 | Inhibition of human neuraminidase 2 expressed in Escherichia coli using 4MU-NANA as substrate after 30 mins by fluorescence assay | 2013 | Journal of medicinal chemistry, Apr-11, Volume: 56, Issue:7
| Identification of selective inhibitors for human neuraminidase isoenzymes using C4,C7-modified 2-deoxy-2,3-didehydro-N-acetylneuraminic acid (DANA) analogues. |
AID704188 | Inhibition of Influenza A virus sialidase N2 by fluorometric assay | 2012 | Journal of medicinal chemistry, Oct-25, Volume: 55, Issue:20
| Exploring the interactions of unsaturated glucuronides with influenza virus sialidase. |
AID729048 | Selectivity ratio of IC50 for human neuraminidase 4 to IC50 for human neuraminidase 2 | 2013 | Journal of medicinal chemistry, Apr-11, Volume: 56, Issue:7
| Identification of selective inhibitors for human neuraminidase isoenzymes using C4,C7-modified 2-deoxy-2,3-didehydro-N-acetylneuraminic acid (DANA) analogues. |
AID729056 | Inhibition of human neuraminidase 1 using 4MU-NANA as substrate after 30 mins by fluorescence assay | 2013 | Journal of medicinal chemistry, Apr-11, Volume: 56, Issue:7
| Identification of selective inhibitors for human neuraminidase isoenzymes using C4,C7-modified 2-deoxy-2,3-didehydro-N-acetylneuraminic acid (DANA) analogues. |
AID203529 | Compound was tested for inhibitory concentration against Influenza sialidase type B | 1998 | Journal of medicinal chemistry, Mar-12, Volume: 41, Issue:6
| Dihydropyrancarboxamides related to zanamivir: a new series of inhibitors of influenza virus sialidases. 2. Crystallographic and molecular modeling study of complexes of 4-amino-4H-pyran-6-carboxamides and sialidase from influenza virus types A and B. |
AID203531 | Compound was tested for inhibitory concentration against Influenza sialidase type A | 1998 | Journal of medicinal chemistry, Mar-12, Volume: 41, Issue:6
| Dihydropyrancarboxamides related to zanamivir: a new series of inhibitors of influenza virus sialidases. 2. Crystallographic and molecular modeling study of complexes of 4-amino-4H-pyran-6-carboxamides and sialidase from influenza virus types A and B. |
AID729058 | Inhibition of Vibrio cholerae neuraminidase | 2013 | Journal of medicinal chemistry, Apr-11, Volume: 56, Issue:7
| Identification of selective inhibitors for human neuraminidase isoenzymes using C4,C7-modified 2-deoxy-2,3-didehydro-N-acetylneuraminic acid (DANA) analogues. |
AID636870 | Inhibition of influenza A virus neuraminidase | 2011 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 21, Issue:23
| The de-guanidinylated derivative of peramivir remains a potent inhibitor of influenza neuraminidase. |
AID729054 | Inhibition of human neuraminidase 4 using 4MU-NANA as substrate after 30 mins by fluorescence assay | 2013 | Journal of medicinal chemistry, Apr-11, Volume: 56, Issue:7
| Identification of selective inhibitors for human neuraminidase isoenzymes using C4,C7-modified 2-deoxy-2,3-didehydro-N-acetylneuraminic acid (DANA) analogues. |
AID977610 | Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB | 2001 | Protein science : a publication of the Protein Society, Apr, Volume: 10, Issue:4
| Analysis of inhibitor binding in influenza virus neuraminidase. |
AID1811 | Experimentally measured binding affinity data derived from PDB | 2001 | Protein science : a publication of the Protein Society, Apr, Volume: 10, Issue:4
| Analysis of inhibitor binding in influenza virus neuraminidase. |
AID1811 | Experimentally measured binding affinity data derived from PDB | 1998 | Structure (London, England : 1993), Jun-15, Volume: 6, Issue:6
| Drug design against a shifting target: a structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase. |
AID977610 | Experimentally measured binding affinity data (Ki) for protein-ligand complexes derived from PDB | 1998 | Structure (London, England : 1993), Jun-15, Volume: 6, Issue:6
| Drug design against a shifting target: a structural basis for resistance to inhibitors in a variant of influenza virus neuraminidase. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |