| Protein | Synonyms | Taxonomy |
|---|
| Porphobilinogen deaminase | PBG-D; EC 2.5.1.61; Hydroxymethylbilane synthase; HMBS; Pre-uroporphyrinogen synthase | Homo sapiens (human) |
| 5-aminolevulinate synthase, erythroid-specific, mitochondrial | ALAS-E; EC 2.3.1.37; 5-aminolevulinic acid synthase 2; Delta-ALA synthase 2; Delta-aminolevulinate synthase 2 | Homo sapiens (human) |
| Ferrochelatase, mitochondrial | EC 4.99.1.1; Heme synthase; Protoheme ferro-lyase | Homo sapiens (human) |
| Multidrug resistance-associated protein 1 | EC 7.6.2.2; ATP-binding cassette sub-family C member 1; Glutathione-S-conjugate-translocating ATPase ABCC1; 7.6.2.3; Leukotriene C(4) transporter; LTC4 transporter | Homo sapiens (human) |
| Canalicular multispecific organic anion transporter 1 | ATP-binding cassette sub-family C member 2; Canalicular multidrug resistance protein; Multidrug resistance-associated protein 2; 7.6.2.2 | Homo sapiens (human) |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | EC 7.6.2.2; ATP-binding cassette sub-family G member 2; Breast cancer resistance protein; CDw338; Mitoxantrone resistance-associated protein; Placenta-specific ATP-binding cassette transporter; Urate exporter | Homo sapiens (human) |
| Solute carrier organic anion transporter family member 1B1 | Liver-specific organic anion transporter 1; LST-1; OATP-C; Sodium-independent organic anion-transporting polypeptide 2; OATP-2; Solute carrier family 21 member 6 | Homo sapiens (human) |
| Uroporphyrinogen decarboxylase | UPD; URO-D; EC 4.1.1.37 | Homo sapiens (human) |
| Albumin | | Homo sapiens (human) |
| Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial | COX; Coprogen oxidase; Coproporphyrinogenase; EC 1.3.3.3 | Homo sapiens (human) |
| Delta-aminolevulinic acid dehydratase | ALADH; EC 4.2.1.24; Porphobilinogen synthase | Homo sapiens (human) |
| UDP-glucuronosyltransferase 1A1 | UGT1A1; EC 2.4.1.17; Bilirubin-specific UDPGT isozyme 1; hUG-BR1; UDP-glucuronosyltransferase 1-1; UDPGT 1-1; UGT1*1; UGT1-01; UGT1.1; UDP-glucuronosyltransferase 1A isoform 1 | Homo sapiens (human) |
| Protoporphyrinogen oxidase | PPO; EC 1.3.3.4 | Homo sapiens (human) |
| Solute carrier organic anion transporter family member 1B3 | Liver-specific organic anion transporter 2; LST-2; Organic anion transporter 8; Organic anion-transporting polypeptide 8; OATP-8; Solute carrier family 21 member 8 | Homo sapiens (human) |
| Uroporphyrinogen-III synthase | UROIIIS; UROS; EC 4.2.1.75; Hydroxymethylbilane hydrolyase [cyclizing]; Uroporphyrinogen-III cosynthase | Homo sapiens (human) |
| UDP-glucuronosyltransferase 1A4 | UGT1A4; EC 2.4.1.17; Bilirubin-specific UDPGT isozyme 2; hUG-BR2; UDP-glucuronosyltransferase 1-4; UDPGT 1-4; UGT1*4; UGT1-04; UGT1.4; UDP-glucuronosyltransferase 1-D; UGT-1D; UGT1D | Homo sapiens (human) |
| 5-aminolevulinate synthase, nonspecific, mitochondrial | ALAS-H; EC 2.3.1.37; 5-aminolevulinic acid synthase 1; Delta-ALA synthase 1; Delta-aminolevulinate synthase 1 | Homo sapiens (human) |
| Protoheme IX farnesyltransferase, mitochondrial | EC 2.5.1.141; Heme O synthase | Homo sapiens (human) |
| Cytochrome c oxidase assembly protein COX15 homolog | | Homo sapiens (human) |
| Beta-galactosidase | | Clostridium perfringens |
| Compound | Description |
|---|
| hydronium ion | |
| Ammonium | |
| iron | A metallic element with atomic symbol Fe, atomic number 26, and atomic weight 55.85. It is an essential constituent of HEMOGLOBINS; CYTOCHROMES; and IRON-BINDING PROTEINS. It plays a role in cellular redox reactions and in the transport of OXYGEN. |
| Carbon Dioxide | A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. |
| carbon monoxide | Carbon monoxide (CO). A poisonous colorless, odorless, tasteless gas. It combines with hemoglobin to form carboxyhemoglobin, which has no oxygen carrying capacity. The resultant oxygen deprivation causes headache, dizziness, decreased pulse and respiratory rates, unconsciousness, and death. (From Merck Index, 11th ed) |
| Zinc | A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn. |
| Orthophosphate | |
| lead | A soft, grayish metal with poisonous salts; atomic number 82, atomic weight 207.2, symbol Pb. |
| uridine diphosphate | A uracil nucleotide containing a pyrophosphate group esterified to C5 of the sugar moiety. |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| Hydrogen Peroxide | A strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| succinyl-coenzyme A | |
| preuroporphyrinogen | |
| uroporphyrinogen iii | |
| protoporphyrinogen | |
| dipyrromethane | structure in first source |
| heme O | hemes of cytochrome o; heme A-like molecule, containing a 17-carbon hydroxyethylfarnesyl side chain but with a methyl residue replacing the formyl group |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| coproporphyrinogen iii | |
| farnesyl pyrophosphate | a sesquiterpene that dimerizes to SQUALENE; RN given refers to cpd without isomeric designation |
| protoporphyrin ix | RN given refers to parent cpd; structure in Merck Index, 9th ed, #7685 |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| stercobilin | RN given refers to (2R,3R,4S,16S,17R,18R)-isomer |
| urobilin | |
| Porphobilinogen | |
| Bilirubin | A bile pigment that is a degradation product of HEME. |
| Coenzyme A | |
| Biliverdine | 1,3,6,7-Tetramethyl-4,5-dicarboxyethyl-2,8-divinylbilenone. Biosynthesized from hemoglobin as a precursor of bilirubin. Occurs in the bile of AMPHIBIANS and of birds, but not in normal human bile or serum. |
| Flavin-Adenine Dinucleotide | A condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972) |
| heme | The color-furnishing portion of hemoglobin. It is found free in tissues and as the prosthetic group in many hemeproteins. |
| creolin | from refined coal tar oils |