| Protein | Synonyms | Taxonomy |
|---|
| Serine--pyruvate aminotransferase | SPT; EC 2.6.1.51; Alanine--glyoxylate aminotransferase; AGT; 2.6.1.44 | Homo sapiens (human) |
| Cystathionine gamma-lyase | EC 4.4.1.1; Cysteine-protein sulfhydrase; Gamma-cystathionase | Homo sapiens (human) |
| Serine hydroxymethyltransferase, mitochondrial | SHMT; EC 2.1.2.1; Glycine hydroxymethyltransferase; Serine methylase | Homo sapiens (human) |
| Amine oxidase [flavin-containing] A | EC 1.4.3.4; Monoamine oxidase type A; MAO-A | Homo sapiens (human) |
| Serine hydroxymethyltransferase, cytosolic | SHMT; EC 2.1.2.1; Glycine hydroxymethyltransferase; Serine methylase | Homo sapiens (human) |
| Serine racemase | EC 5.1.1.18; D-serine ammonia-lyase; D-serine dehydratase; 4.3.1.18; L-serine ammonia-lyase; L-serine dehydratase; 4.3.1.17 | Homo sapiens (human) |
| Aldehyde dehydrogenase, mitochondrial | EC 1.2.1.3; ALDH class 2; ALDH-E2; ALDHI | Homo sapiens (human) |
| D-3-phosphoglycerate dehydrogenase | 3-PGDH; EC 1.1.1.95; 2-oxoglutarate reductase; 1.1.1.399; Malate dehydrogenase; 1.1.1.37 | Homo sapiens (human) |
| Serine--tRNA ligase, cytoplasmic | EC 6.1.1.11; Seryl-tRNA synthetase; SerRS; Seryl-tRNA(Ser/Sec) synthetase | Homo sapiens (human) |
| Guanidinoacetate N-methyltransferase | EC 2.1.1.2 | Homo sapiens (human) |
| Glycine N-methyltransferase | EC 2.1.1.20 | Homo sapiens (human) |
| Phosphoserine phosphatase | PSP; PSPase; EC 3.1.3.3; L-3-phosphoserine phosphatase; O-phosphoserine phosphohydrolase | Homo sapiens (human) |
| Glycine--tRNA ligase | EC 6.1.1.14; Diadenosine tetraphosphate synthetase; Ap4A synthetase; 2.7.7.-; Glycyl-tRNA synthetase; GlyRS; Glycyl-tRNA synthetase 1 | Homo sapiens (human) |
| L-serine dehydratase/L-threonine deaminase | SDH; EC 4.3.1.17; L-serine deaminase; L-threonine dehydratase; TDH; 4.3.1.19 | Homo sapiens (human) |
| Dihydrolipoyl dehydrogenase, mitochondrial | EC 1.8.1.4; Dihydrolipoamide dehydrogenase; Glycine cleavage system L protein | Homo sapiens (human) |
| Phosphoserine aminotransferase | EC 2.6.1.52; Phosphohydroxythreonine aminotransferase; PSAT | Homo sapiens (human) |
| 5-aminolevulinate synthase, nonspecific, mitochondrial | ALAS-H; EC 2.3.1.37; 5-aminolevulinic acid synthase 1; Delta-ALA synthase 1; Delta-aminolevulinate synthase 1 | Homo sapiens (human) |
| Glycerate kinase | EC 2.7.1.31; HBeAg-binding protein 4 | Homo sapiens (human) |
| Sarcosine dehydrogenase, mitochondrial | SarDH; EC 1.5.8.3; BPR-2 | Homo sapiens (human) |
| Dimethylglycine dehydrogenase, mitochondrial | EC 1.5.8.4; ME2GLYDH | Homo sapiens (human) |
| 2-amino-3-ketobutyrate coenzyme A ligase, mitochondrial | AKB ligase; EC 2.3.1.29; Aminoacetone synthase; Glycine acetyltransferase | Homo sapiens (human) |
| Glycine dehydrogenase (decarboxylating), mitochondrial | EC 1.4.4.2; Glycine cleavage system P protein; Glycine decarboxylase; Glycine dehydrogenase (aminomethyl-transferring) | Homo sapiens (human) |
| Aminomethyltransferase, mitochondrial | EC 2.1.2.10; Glycine cleavage system T protein; GCVT | Homo sapiens (human) |
| Glycine amidinotransferase, mitochondrial | EC 2.1.4.1; L-arginine:glycine amidinotransferase; Transamidinase | Homo sapiens (human) |
| Compound | Description |
|---|
| pyruvic acid | An intermediate compound in the metabolism of carbohydrates, proteins, and fats. In thiamine deficiency, its oxidation is retarded and it accumulates in the tissues, especially in nervous structures. (From Stedman, 26th ed) |
| Orthophosphate | |
| aminolevulinic acid | A compound produced from succinyl-CoA and GLYCINE as an intermediate in heme synthesis. It is used as a PHOTOCHEMOTHERAPY for actinic KERATOSIS. |
| ammonium hydroxide | The hydroxy salt of ammonium ion. It is formed when AMMONIA reacts with water molecules in solution. |
| betaine | A naturally occurring compound that has been of interest for its role in osmoregulation. As a drug, betaine hydrochloride has been used as a source of hydrochloric acid in the treatment of hypochlorhydria. Betaine has also been used in the treatment of liver disorders, for hyperkalemia, for homocystinuria, and for gastrointestinal disturbances. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1341) |
| Carbon Dioxide | A colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals. |
| glutamic acid | A non-essential amino acid naturally occurring in the L-form. Glutamic acid is the most common excitatory neurotransmitter in the CENTRAL NERVOUS SYSTEM. |
| NADH | |
| creatine | An amino acid that occurs in vertebrate tissues and in urine. In muscle tissue, creatine generally occurs as phosphocreatine. Creatine is excreted as CREATININE in the urine. |
| cysteine | A thiol-containing non-essential amino acid that is oxidized to form CYSTINE. |
| Adenosine Triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| adenosine monophosphate | Adenine nucleotide containing one phosphate group esterified to the sugar moiety in the 2'-, 3'-, or 5'-position. |
| berlition | antioxidant preparation containing alpha-lipoic acid, used in the neuroprotective therapy of chronic brain ischemia for correction of free-radical processes |
| methionine | A sulfur-containing essential L-amino acid that is important in many body functions. |
| formaldehyde | A highly reactive aldehyde gas formed by oxidation or incomplete combustion of hydrocarbons. In solution, it has a wide range of uses: in the manufacture of resins and textiles, as a disinfectant, and as a laboratory fixative or preservative. Formaldehyde solution (formalin) is considered a hazardous compound, and its vapor toxic. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p717) |
| Hydrogen Peroxide | A strong oxidizing agent used in aqueous solution as a ripening agent, bleach, and topical anti-infective. It is relatively unstable and solutions deteriorate over time unless stabilized by the addition of acetanilide or similar organic materials. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| Coenzyme A | |
| phosphohydroxypyruvic acid | |
| sarcosine | An amino acid intermediate in the metabolism of choline. |
| aminoacetone | RN given refers to parent cpd |
| dihydrolipoic acid | RN given refers to parent cpd without isomeric designation |
| glyceric acid | found in urine of patient with D-glyceric acidemia & hyperglycinaemia; RN given refers to parent cpd without isomeric designation |
| 2-amino-3-ketobutyrate | unstable intermediate in threonine dehydrogenase-initiated pathway for threonine utilization; structure given in first source |
| alpha-ketoglutaric acid | |
| alpha-ketobutyric acid | RN given refers to parent cpd; structure |
| NAD | A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed) |
| alanine | A non-essential amino acid that occurs in high levels in its free state in plasma. It is produced from pyruvate by transamination. It is involved in sugar and acid metabolism, increases IMMUNITY, and provides energy for muscle tissue, BRAIN, and the CENTRAL NERVOUS SYSTEM. |
| serine | A non-essential amino acid occurring in natural form as the L-isomer. It is synthesized from GLYCINE or THREONINE. It is involved in the biosynthesis of PURINES; PYRIMIDINES; and other amino acids. |
| dimethylglycine | metabolic product of calcium pangamate; mutagen when mixed with nitrite; RN given refers to parent cpd |
| 3-phosphoglycerate | |
| glyoxylic acid | RN given refers to parent cpd |
| pyruvaldehyde | An organic compound used often as a reagent in organic synthesis, as a flavoring agent, and in tanning. It has been demonstrated as an intermediate in the metabolism of acetone and its derivatives in isolated cell preparations, in various culture media, and in vivo in certain animals. |
| orotidylic acid | structure |
| s-adenosylmethionine | Physiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed) |
| acetyl coenzyme a | Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent. |
| pyrophosphate | |
| hydroxypyruvic acid | RN given refers to parent cpd |