| Protein | Synonyms | Taxonomy |
|---|
| Interleukin-10 | IL-10; Cytokine synthesis inhibitory factor; CSIF | Homo sapiens (human) |
| Actin-related protein 3 | Actin-like protein 3 | Homo sapiens (human) |
| Tyrosine-protein kinase ABL1 | EC 2.7.10.2; Abelson murine leukemia viral oncogene homolog 1; Abelson tyrosine-protein kinase 1; Proto-oncogene c-Abl; p150 | Homo sapiens (human) |
| Heat shock protein HSP 90-beta | HSP 90; Heat shock 84 kDa; HSP 84; HSP84 | Homo sapiens (human) |
| Cathepsin G | CG; EC 3.4.21.20 | Homo sapiens (human) |
| Mitogen-activated protein kinase 3 | MAP kinase 3; MAPK 3; EC 2.7.11.24; ERT2; Extracellular signal-regulated kinase 1; ERK-1; Insulin-stimulated MAP2 kinase; MAP kinase isoform p44; p44-MAPK; Microtubule-associated protein 2 kinase; p44-ERK1 | Homo sapiens (human) |
| Mitogen-activated protein kinase 1 | MAP kinase 1; MAPK 1; EC 2.7.11.24; ERT1; Extracellular signal-regulated kinase 2; ERK-2; MAP kinase isoform p42; p42-MAPK; Mitogen-activated protein kinase 2; MAP kinase 2; MAPK 2 | Homo sapiens (human) |
| Tyrosine-protein kinase SYK | EC 2.7.10.2; Spleen tyrosine kinase; p72-Syk | Homo sapiens (human) |
| Disintegrin and metalloproteinase domain-containing protein 17 | ADAM 17; EC 3.4.24.86; Snake venom-like protease; TNF-alpha convertase; TNF-alpha-converting enzyme | Homo sapiens (human) |
| Transcription factor p65 | Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 | Homo sapiens (human) |
| Dedicator of cytokinesis protein 1 | 180 kDa protein downstream of CRK; DOCK180 | Homo sapiens (human) |
| Transcription factor AP-1 | Activator protein 1; AP1; Proto-oncogene c-Jun; V-jun avian sarcoma virus 17 oncogene homolog; p39 | Homo sapiens (human) |
| Heme oxygenase 1 | HO-1; EC 1.14.14.18 | Homo sapiens (human) |
| Furin | EC 3.4.21.75; Dibasic-processing enzyme; Paired basic amino acid residue-cleaving enzyme; PACE | Homo sapiens (human) |
| Adenosine receptor A2b | | Homo sapiens (human) |
| Caspase-1 | CASP-1; EC 3.4.22.36; Interleukin-1 beta convertase; IL-1BC; Interleukin-1 beta-converting enzyme; ICE; IL-1 beta-converting enzyme; p45 | Homo sapiens (human) |
| Mitogen-activated protein kinase 8 | MAP kinase 8; MAPK 8; EC 2.7.11.24; JNK-46; Stress-activated protein kinase 1c; SAPK1c; Stress-activated protein kinase JNK1; c-Jun N-terminal kinase 1 | Homo sapiens (human) |
| Cell division control protein 42 homolog | EC 3.6.5.2; G25K GTP-binding protein | Homo sapiens (human) |
| Actin-related protein 2/3 complex subunit 5 | Arp2/3 complex 16 kDa subunit; p16-ARC | Homo sapiens (human) |
| S-adenosylhomocysteine hydrolase-like protein 1 | DC-expressed AHCY-like molecule; IP(3)Rs binding protein released with IP(3); IRBIT; Putative adenosylhomocysteinase 2; S-adenosyl-L-homocysteine hydrolase 2; AdoHcyase 2 | Homo sapiens (human) |
| Dipeptidase 1 | EC 3.4.13.19; Beta-lactamase; 3.5.2.6; Dehydropeptidase-I; Microsomal dipeptidase; Renal dipeptidase; hRDP | Homo sapiens (human) |
| Cyclic AMP-responsive element-binding protein 1 | CREB-1; cAMP-responsive element-binding protein 1 | Homo sapiens (human) |
| Adapter molecule crk | Proto-oncogene c-Crk; p38 | Homo sapiens (human) |
| Ras-related C3 botulinum toxin substrate 1 | EC 3.6.5.2; Cell migration-inducing gene 5 protein; Ras-like protein TC25; p21-Rac1 | Homo sapiens (human) |
| Dipeptidase 2 | EC 3.4.13.19 | Homo sapiens (human) |
| Dipeptidase 3 | EC 3.4.13.19 | Homo sapiens (human) |
| Myosin-9 | Cellular myosin heavy chain, type A; Myosin heavy chain 9; Myosin heavy chain, non-muscle IIa; Non-muscle myosin heavy chain A; NMMHC-A; Non-muscle myosin heavy chain IIa; NMMHC II-a; NMMHC-IIA | Homo sapiens (human) |
| NACHT, LRR and PYD domains-containing protein 3 | Angiotensin/vasopressin receptor AII/AVP-like; Caterpiller protein 1.1; CLR1.1; Cold-induced autoinflammatory syndrome 1 protein; Cryopyrin; PYRIN-containing APAF1-like protein 1 | Homo sapiens (human) |
| Frizzled-7 | Fz-7; hFz7; FzE3 | Homo sapiens (human) |
| Ectonucleoside triphosphate diphosphohydrolase 5 | NTPDase 5; EC 3.6.1.6; CD39 antigen-like 4; ER-UDPase; Guanosine-diphosphatase ENTPD5; GDPase ENTPD5; 3.6.1.42; Nucleoside diphosphatase; Uridine-diphosphatase ENTPD5; UDPase ENTPD5 | Homo sapiens (human) |
| Gasdermin-D | Gasdermin domain-containing protein 1 | Homo sapiens (human) |
| Interleukin-6 | IL-6; B-cell stimulatory factor 2; BSF-2; CTL differentiation factor; CDF; Hybridoma growth factor; Interferon beta-2; IFN-beta-2 | Homo sapiens (human) |
| Calmodulin-1 | | Homo sapiens (human) |
| Thioredoxin | Trx; ATL-derived factor; ADF; Surface-associated sulphydryl protein; SASP | Homo sapiens (human) |
| 5'-nucleotidase | 5'-NT; EC 3.1.3.5; Ecto-5'-nucleotidase | Homo sapiens (human) |
| Ectonucleoside triphosphate diphosphohydrolase 1 | NTPDase 1; EC 3.6.1.5; Ecto-ATP diphosphohydrolase 1; Ecto-ATPDase 1; Ecto-ATPase 1; Ecto-apyrase; Lymphoid cell activation antigen | Homo sapiens (human) |
| C3a anaphylatoxin chemotactic receptor | C3AR; C3a-R | Homo sapiens (human) |
| NADPH oxidase 1 | NOX-1; EC 1.-.-.-; Mitogenic oxidase 1; MOX-1; NADH/NADPH mitogenic oxidase subunit P65-MOX; NOH-1 | Homo sapiens (human) |
| Complement C3 | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1 | Homo sapiens (human) |
| Glutathione hydrolase 1 proenzyme | EC 3.4.19.13; Gamma-glutamyltransferase 1; Gamma-glutamyltranspeptidase 1; GGT 1; 2.3.2.2; Leukotriene-C4 hydrolase; 3.4.19.14 | Homo sapiens (human) |
| Actin-related protein 2/3 complex subunit 1B | Arp2/3 complex 41 kDa subunit; p41-ARC | Homo sapiens (human) |
| Actin-related protein 2/3 complex subunit 2 | Arp2/3 complex 34 kDa subunit; p34-ARC | Homo sapiens (human) |
| Protein BRICK1 | BRK1 | Homo sapiens (human) |
| Apoptosis-associated speck-like protein containing a CARD | hASC; Caspase recruitment domain-containing protein 5; PYD and CARD domain-containing protein; Target of methylation-induced silencing 1 | Homo sapiens (human) |
| Actin-related protein 2 | Actin-like protein 2 | Homo sapiens (human) |
| Pyrin | Marenostrin | Homo sapiens (human) |
| Actin-related protein 2/3 complex subunit 1A | SOP2-like protein | Homo sapiens (human) |
| Protein Wnt-5a | | Homo sapiens (human) |
| Thioredoxin-interacting protein | Thioredoxin-binding protein 2; Vitamin D3 up-regulated protein 1 | Homo sapiens (human) |
| Proline-serine-threonine phosphatase-interacting protein 1 | PEST phosphatase-interacting protein 1; CD2-binding protein 1; H-PIP | Homo sapiens (human) |
| Actin-related protein 2/3 complex subunit 3 | Arp2/3 complex 21 kDa subunit; p21-ARC | Homo sapiens (human) |
| Low affinity immunoglobulin gamma Fc region receptor III-A | CD16a antigen; Fc-gamma RIII-alpha; Fc-gamma RIII; Fc-gamma RIIIa; FcRIII; FcRIIIa; FcR-10; IgG Fc receptor III-2 | Homo sapiens (human) |
| Cytochrome b-245 light chain | Cytochrome b(558) alpha chain; Cytochrome b558 subunit alpha; Neutrophil cytochrome b 22 kDa polypeptide; Superoxide-generating NADPH oxidase light chain subunit; p22 phagocyte B-cytochrome; p22-phox; p22phox | Homo sapiens (human) |
| Guanine nucleotide-binding protein G(z) subunit alpha | G(x) alpha chain; Gz-alpha | Homo sapiens (human) |
| Glutathione hydrolase 5 proenzyme | EC 3.4.19.13; Gamma-glutamyl transpeptidase-related enzyme; GGT-rel; Gamma-glutamyltransferase 5; GGT 5; 2.3.2.2; Gamma-glutamyltransferase-like activity 1; Gamma-glutamyltranspeptidase 5; Leukotriene-C4 hydrolase; 3.4.19.14 | Homo sapiens (human) |
| Nck-associated protein 1-like | Hematopoietic protein 1; Membrane-associated protein HEM-1 | Homo sapiens (human) |
| Actin-related protein 2/3 complex subunit 4 | Arp2/3 complex 20 kDa subunit; p20-ARC | Homo sapiens (human) |
| Inactive rhomboid protein 2 | iRhom2; Rhomboid 5 homolog 2; Rhomboid family member 2; Rhomboid veinlet-like protein 5; Rhomboid veinlet-like protein 6 | Homo sapiens (human) |
| NADPH oxidase activator 1 | NOX activator 1; Antigen NY-CO-31; NCF2-like protein; P67phox-like factor; p51-nox | Homo sapiens (human) |
| Scavenger receptor cysteine-rich type 1 protein M130 | Hemoglobin scavenger receptor | Homo sapiens (human) |
| NADPH oxidase organizer 1 | NADPH oxidase regulatory protein; Nox organizer 1; Nox-organizing protein 1; SH3 and PX domain-containing protein 5 | Homo sapiens (human) |
| Unconventional myosin-X | Unconventional myosin-10 | Homo sapiens (human) |
| Brain-specific angiogenesis inhibitor 1-associated protein 2 | BAI-associated protein 2; BAI1-associated protein 2; Protein BAP2; Fas ligand-associated factor 3; FLAF3; Insulin receptor substrate p53/p58; IRS-58; IRSp53/58; Insulin receptor substrate protein of 53 kDa; IRSp53; Insulin receptor substrate p53 | Homo sapiens (human) |
| Nck-associated protein 1 | NAP 1; Membrane-associated protein HEM-2; p125Nap1 | Homo sapiens (human) |
| Protein SGT1 homolog | Protein 40-6-3; Sgt1; Suppressor of G2 allele of SKP1 homolog | Homo sapiens (human) |
| Putative GIPL galf transferase | | Leishmania major |
| Compound | Description |
|---|
| hydronium ion | |
| Calcium | A basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes. |
| Zinc | A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn. |
| Orthophosphate | |
| Superoxides | Highly reactive compounds produced when oxygen is reduced by a single electron. In biological systems, they may be generated during the normal catalytic function of a number of enzymes and during the oxidation of hemoglobin to METHEMOGLOBIN. In living organisms, SUPEROXIDE DISMUTASE protects the cell from the deleterious effects of superoxides. |
| adenosine | A nucleoside that is composed of ADENINE and D-RIBOSE. Adenosine or adenosine derivatives play many important biological roles in addition to being components of DNA and RNA. Adenosine itself is a neurotransmitter. |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| Magnesium | A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| Guanosine Monophosphate | A guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature. |
| Guanosine Diphosphate | A guanine nucleotide containing two phosphate groups esterified to the sugar moiety. |
| nad | A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed) |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| nicotinamide-beta-riboside | |
| leukotriene c4 | The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some VASCULAR SMOOTH MUSCLE. (From Dictionary of Prostaglandins and Related Compounds, 1990) |
| leukotriene d4 | One of the biologically active principles of SRS-A. It is generated from LEUKOTRIENE C4 after partial hydrolysis of the peptide chain, i.e., cleavage of the gamma-glutamyl portion. Its biological actions include stimulation of vascular and nonvascular smooth muscle, and increases in vascular permeability. (From Dictionary of Prostaglandins and Related Compounds, 1990) |
| leukotriene e4 | A biologically active principle of SRS-A that is formed from LEUKOTRIENE D4 via a peptidase reaction that removes the glycine residue. The biological actions of LTE4 are similar to LTC4 and LTD4. (From Dictionary of Prostaglandins and Related Compounds, 1990) |
| glutamate | |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| cyclic amp | An adenine nucleotide containing one phosphate group which is esterified to both the 3'- and 5'-positions of the sugar moiety. It is a second messenger and a key intracellular regulator, functioning as a mediator of activity for a number of hormones, including epinephrine, glucagon, and ACTH. |