Page last updated: 2024-10-06

Chromatin organization

Proteins (120)

ProteinSynonymsTaxonomy
Histone acetyltransferase type B catalytic subunitEC 2.3.1.48; Histone acetyltransferase 1Homo sapiens (human)
Histone acetyltransferase KAT7EC 2.3.1.48; Histone acetyltransferase binding to ORC1; Lysine acetyltransferase 7; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 2; MYST-2Homo sapiens (human)
Paired box protein Pax-3HuP2Homo sapiens (human)
AT-rich interactive domain-containing protein 4AARID domain-containing protein 4A; Retinoblastoma-binding protein 1; RBBP-1Homo sapiens (human)
N-lysine methyltransferase SETD6EC 2.1.1.-; SET domain-containing protein 6Homo sapiens (human)
Histone acetyltransferase KAT6AEC 2.3.1.48; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3; MYST-3; Monocytic leukemia zinc finger protein; Runt-related transcription factor-binding protein 2; Zinc finger protein 220Homo sapiens (human)
Histone deacetylase 3HD3; EC 3.5.1.98; RPD3-2; SMAP45Homo sapiens (human)
Lysine-specific histone demethylase 1AEC 1.14.99.66; BRAF35-HDAC complex protein BHC110; Flavin-containing amine oxidase domain-containing protein 2; [histone H3]-dimethyl-L-lysine(4) FAD-dependent demethylase 1AHomo sapiens (human)
Tyrosine-protein kinase JAK2EC 2.7.10.2; Janus kinase 2; JAK-2Homo sapiens (human)
G1/S-specific cyclin-D1B-cell lymphoma 1 protein; BCL-1; BCL-1 oncogene; PRAD1 oncogeneHomo sapiens (human)
Transcription factor p65Nuclear factor NF-kappa-B p65 subunit; Nuclear factor of kappa light polypeptide gene enhancer in B-cells 3Homo sapiens (human)
Histone-lysine N-methyltransferase, H3 lysine-79 specificEC 2.1.1.360; DOT1-like protein; Histone H3-K79 methyltransferase; H3-K79-HMTase; Lysine N-methyltransferase 4Homo sapiens (human)
Polyamine deacetylase HDAC10EC 3.5.1.48; EC 3.5.1.62; Histone deacetylase 10; HD10Homo sapiens (human)
Histone deacetylase 8HD8; EC 3.5.1.98Homo sapiens (human)
F-box-like/WD repeat-containing protein TBL1XR1Nuclear receptor corepressor/HDAC3 complex subunit TBLR1; TBL1-related protein 1; Transducin beta-like 1X-related protein 1Homo sapiens (human)
Cyclin-dependent kinase 4EC 2.7.11.22; Cell division protein kinase 4; PSK-J3Homo sapiens (human)
Histone acetyltransferase p300p300 HAT; EC 2.3.1.48; E1A-associated protein p300; Histone butyryltransferase p300; 2.3.1.-; Histone crotonyltransferase p300; 2.3.1.-; Protein 2-hydroxyisobutyryltransferase p300; 2.3.1.-; Protein propionyltransferase p300; 2.3.1.-Homo sapiens (human)
Histone-lysine N-methyltransferase EHMT2EC 2.1.1.-; Euchromatic histone-lysine N-methyltransferase 2; HLA-B-associated transcript 8; Histone H3-K9 methyltransferase 3; H3-K9-HMTase 3; Lysine N-methyltransferase 1C; Protein G9aHomo sapiens (human)
Protein arginine N-methyltransferase 6EC 2.1.1.319; Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6; Histone-arginine N-methyltransferase PRMT6Homo sapiens (human)
Histone-lysine N-methyltransferase EHMT1EC 2.1.1.-; Euchromatic histone-lysine N-methyltransferase 1; Eu-HMTase1; G9a-like protein 1; GLP; GLP1; Histone H3-K9 methyltransferase 5; H3-K9-HMTase 5; Lysine N-methyltransferase 1DHomo sapiens (human)
YEATS domain-containing protein 4Glioma-amplified sequence 41; Gas41; NuMA-binding protein 1; NuBI-1; NuBI1Homo sapiens (human)
YEATS domain-containing protein 2Homo sapiens (human)
Bromodomain-containing protein 8Skeletal muscle abundant protein; Skeletal muscle abundant protein 2; Thyroid hormone receptor coactivating protein of 120 kDa; TrCP120; p120Homo sapiens (human)
Protein Dr1Down-regulator of transcription 1; Negative cofactor 2-beta; NC2-beta; TATA-binding protein-associated phosphoproteinHomo sapiens (human)
Histone acetyltransferase KAT2AEC 2.3.1.48; General control of amino acid synthesis protein 5-like 2; Histone acetyltransferase GCN5; hGCN5; Histone glutaryltransferase KAT2A; 2.3.1.-; Histone succinyltransferase KAT2A; 2.3.1.-; Lysine acetyltransferase 2A; STAF97Homo sapiens (human)
Nuclear receptor coactivator 1NCoA-1; EC 2.3.1.48; Class E basic helix-loop-helix protein 74; bHLHe74; Protein Hin-2; RIP160; Renal carcinoma antigen NY-REN-52; Steroid receptor coactivator 1; SRC-1Homo sapiens (human)
Histone acetyltransferase KAT8EC 2.3.1.48; Lysine acetyltransferase 8; MOZ, YBF2/SAS3, SAS2 and TIP60 protein 1; MYST-1; hMOFHomo sapiens (human)
RuvB-like 2EC 3.6.4.12; 48 kDa TATA box-binding protein-interacting protein; 48 kDa TBP-interacting protein; 51 kDa erythrocyte cytosolic protein; ECP-51; INO80 complex subunit J; Repressing pontin 52; Reptin 52; TIP49b; TIP60-associated protein 54-beta; TAP54-betaHomo sapiens (human)
Histone-lysine N-methyltransferase SETD2EC 2.1.1.359; HIF-1; Huntingtin yeast partner B; Huntingtin-interacting protein 1; HIP-1; Huntingtin-interacting protein B; Lysine N-methyltransferase 3A; Protein-lysine N-methyltransferase SETD2; 2.1.1.-; SET domain-containing protein 2; hSET2; p231HBPHomo sapiens (human)
Nuclear receptor coactivator 2NCoA-2; Class E basic helix-loop-helix protein 75; bHLHe75; Transcriptional intermediary factor 2; hTIF2Homo sapiens (human)
Bifunctional arginine demethylase and lysyl-hydroxylase JMJD6EC 1.14.11.-; Histone arginine demethylase JMJD6; JmjC domain-containing protein 6; Jumonji domain-containing protein 6; Lysyl-hydroxylase JMJD6; Peptide-lysine 5-dioxygenase JMJD6; Phosphatidylserine receptor; Protein PTDSRHomo sapiens (human)
SAGA-associated factor 29Coiled-coil domain-containing protein 101; SAGA complex-associated factor 29Homo sapiens (human)
Mortality factor 4-like protein 1MORF-related gene 15 protein; Protein MSL3-1; Transcription factor-like protein MRG15Homo sapiens (human)
Protein arginine N-methyltransferase 5PRMT5; EC 2.1.1.320; 72 kDa ICln-binding protein; Histone-arginine N-methyltransferase PRMT5; Jak-binding protein 1; Shk1 kinase-binding protein 1 homolog; SKB1 homolog; SKB1HsHomo sapiens (human)
Protein arginine N-methyltransferase 3EC 2.1.1.-; Heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 3Homo sapiens (human)
Polycomb protein EEDhEED; Embryonic ectoderm development protein; WD protein associating with integrin cytoplasmic tails 1; WAIT-1Homo sapiens (human)
40S ribosomal protein S240S ribosomal protein S4; Protein LLRep3; Small ribosomal subunit protein uS5Homo sapiens (human)
Actin, cytoplasmic 1Beta-actinHomo sapiens (human)
WD repeat-containing protein 5BMP2-induced 3-kb gene proteinHomo sapiens (human)
Histone H4Homo sapiens (human)
Histone-binding protein RBBP4Chromatin assembly factor 1 subunit C; CAF-1 subunit C; Chromatin assembly factor I p48 subunit; CAF-I 48 kDa subunit; CAF-I p48; Nucleosome-remodeling factor subunit RBAP48; Retinoblastoma-binding protein 4; RBBP-4; Retinoblastoma-binding protein p48Homo sapiens (human)
Histone-lysine N-methyltransferase EZH2EC 2.1.1.356; ENX-1; Enhancer of zeste homolog 2; Lysine N-methyltransferase 6Homo sapiens (human)
Histone-binding protein RBBP7Histone acetyltransferase type B subunit 2; Nucleosome-remodeling factor subunit RBAP46; Retinoblastoma-binding protein 7; RBBP-7; Retinoblastoma-binding protein p46Homo sapiens (human)
Zinc finger protein AEBP2Adipocyte enhancer-binding protein 2; AE-binding protein 2Homo sapiens (human)
Histone-arginine methyltransferase CARM1EC 2.1.1.319; Coactivator-associated arginine methyltransferase 1; Protein arginine N-methyltransferase 4Homo sapiens (human)
CREB-binding proteinHistone lysine acetyltransferase CREBBP; 2.3.1.48; Protein-lysine acetyltransferase CREBBP; 2.3.1.-Homo sapiens (human)
Histone acetyltransferase KAT5EC 2.3.1.48; 60 kDa Tat-interactive protein; Tip60; Histone acetyltransferase HTATIP; HIV-1 Tat interactive protein; Lysine acetyltransferase 5; cPLA(2)-interacting proteinHomo sapiens (human)
Protein arginine N-methyltransferase 1EC 2.1.1.319; Histone-arginine N-methyltransferase PRMT1; Interferon receptor 1-bound protein 4Homo sapiens (human)
Histone lysine demethylase PHF8EC 1.14.11.27; EC 1.14.11.65; PHD finger protein 8; [histone H3]-dimethyl-L-lysine(36) demethylase PHF8; [histone H3]-dimethyl-L-lysine(9) demethylase PHF8Homo sapiens (human)
DNA (cytosine-5)-methyltransferase 3ADnmt3a; EC 2.1.1.37; DNA methyltransferase HsaIIIA; DNA MTase HsaIIIA; M.HsaIIIAHomo sapiens (human)
REST corepressor 1Protein CoRESTHomo sapiens (human)
RuvB-like 1EC 3.6.4.12; 49 kDa TATA box-binding protein-interacting protein; 49 kDa TBP-interacting protein; 54 kDa erythrocyte cytosolic protein; ECP-54; INO80 complex subunit H; Nuclear matrix protein 238; NMP 238; Pontin 52; TIP49a; TIP60-associated protein 54-alHomo sapiens (human)
Ataxin-7Spinocerebellar ataxia type 7 proteinHomo sapiens (human)
Cyclic AMP-dependent transcription factor ATF-2cAMP-dependent transcription factor ATF-2; Activating transcription factor 2; Cyclic AMP-responsive element-binding protein 2; CREB-2; cAMP-responsive element-binding protein 2; HB16; cAMP response element-binding protein CRE-BP1Homo sapiens (human)
Host cell factor 1HCF; HCF-1; C1 factor; CFF; VCAF; VP16 accessory proteinHomo sapiens (human)
Transcription activator BRG1EC 3.6.4.-; ATP-dependent helicase SMARCA4; BRG1-associated factor 190A; BAF190A; Mitotic growth and transcription activator; Protein BRG-1; Protein brahma homolog 1; SNF2-beta; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfHomo sapiens (human)
Polycomb protein SUZ12Chromatin precipitated E2F target 9 protein; ChET 9 protein; Joined to JAZF1 protein; Suppressor of zeste 12 protein homologHomo sapiens (human)
Histone-lysine N-methyltransferase SETDB1EC 2.1.1.366; ERG-associated protein with SET domain; ESET; Histone H3-K9 methyltransferase 4; H3-K9-HMTase 4; Lysine N-methyltransferase 1E; SET domain bifurcated 1Homo sapiens (human)
Methylosome protein 50MEP-50; Androgen receptor cofactor p44; WD repeat-containing protein 77; p44/Mep50Homo sapiens (human)
N-lysine methyltransferase KMT5AEC 2.1.1.-; H4-K20-HMTase KMT5A; Histone-lysine N-methyltransferase KMT5A; 2.1.1.361; Lysine N-methyltransferase 5A; Lysine-specific methylase 5A; PR/SET domain-containing protein 07; PR-Set7; PR/SET07; SET domain-containing protein 8Homo sapiens (human)
Bromodomain and WD repeat-containing protein 1WD repeat-containing protein 9Homo sapiens (human)
Inhibitor of growth protein 5p28ING5Homo sapiens (human)
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunitEC 2.4.1.255; O-GlcNAc transferase subunit p110; O-linked N-acetylglucosamine transferase 110 kDa subunit; OGTHomo sapiens (human)
Histone deacetylase complex subunit SAP130130 kDa Sin3-associated polypeptide; Sin3-associated polypeptide p130Homo sapiens (human)
RE1-silencing transcription factorNeural-restrictive silencer factor; X2 box repressorHomo sapiens (human)
Elongator complex protein 1ELP1; IkappaB kinase complex-associated protein; IKK complex-associated protein; p150Homo sapiens (human)
Elongator complex protein 2ELP2; SHINC-2; STAT3-interacting protein 1; StIP1Homo sapiens (human)
PHD finger protein 20Glioma-expressed antigen 2; Hepatocellular carcinoma-associated antigen 58; Novel zinc finger protein; Transcription factor TZPHomo sapiens (human)
TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 6LTAF6L; PCAF-associated factor 65-alpha; PAF65-alphaHomo sapiens (human)
TAF5-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDa subunit 5LTAF5L; PCAF-associated factor 65 beta; PAF65-betaHomo sapiens (human)
Circadian locomoter output cycles protein kaputhCLOCK; EC 2.3.1.48; Class E basic helix-loop-helix protein 8; bHLHe8Homo sapiens (human)
Ubiquitin carboxyl-terminal hydrolase 22EC 3.4.19.12; Deubiquitinating enzyme 22; Ubiquitin thioesterase 22; Ubiquitin-specific-processing protease 22Homo sapiens (human)
Mortality factor 4-like protein 2MORF-related gene X protein; Protein MSL3-2; Transcription factor-like protein MRGXHomo sapiens (human)
Male-specific lethal 3 homologMale-specific lethal-3 homolog 1; Male-specific lethal-3 protein-like 1; MSL3-like 1Homo sapiens (human)
E1A-binding protein p400EC 3.6.4.-; CAG repeat protein 32; Domino homolog; hDomino; Trinucleotide repeat-containing gene 12 protein; p400 kDa SWI2/SNF2-related proteinHomo sapiens (human)
Activating transcription factor 7-interacting protein 1ATF-interacting protein; ATF-IP; ATF7-interacting protein; ATFa-associated modulator; hAM; MBD1-containing chromatin-associated factor 1; P621Homo sapiens (human)
F-box-like/WD repeat-containing protein TBL1XSMAP55; Transducin beta-like protein 1X; Transducin-beta-like protein 1, X-linkedHomo sapiens (human)
Transcriptional adapter 2-alphaTranscriptional adapter 2-like; ADA2-like proteinHomo sapiens (human)
Transcription initiation protein SPT3 homologSPT3-like proteinHomo sapiens (human)
Transcriptional adapter 3ADA3 homolog; hADA3; STAF54; Transcriptional adapter 3-like; ADA3-like proteinHomo sapiens (human)
STAGA complex 65 subunit gammaAdenocarcinoma antigen ART1; SPTF-associated factor 65 gamma; STAF65gamma; Suppressor of Ty 7-likeHomo sapiens (human)
Methyl-CpG-binding domain protein 3Methyl-CpG-binding protein MBD3Homo sapiens (human)
Actin-like protein 6A53 kDa BRG1-associated factor A; Actin-related protein Baf53a; ArpNbeta; BRG1-associated factor 53A; BAF53A; INO80 complex subunit KHomo sapiens (human)
Elongator complex protein 6Angiotonin-transactivated protein 1; Protein TMEM103Homo sapiens (human)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily B member 1BRG1-associated factor 47; BAF47; Integrase interactor 1 protein; SNF5 homolog; hSNF5Homo sapiens (human)
Transcription initiation factor TFIID subunit 10STAF28; Transcription initiation factor TFIID 30 kDa subunit; TAF(II)30; TAFII-30; TAFII30Homo sapiens (human)
G protein pathway suppressor 2GPS-2Homo sapiens (human)
Ataxin-7-like protein 3SAGA-associated factor 11 homologHomo sapiens (human)
Vacuolar protein sorting-associated protein 72 homologProtein YL-1; Transcription factor-like 1Homo sapiens (human)
Transcription initiation factor TFIID subunit 12Transcription initiation factor TFIID 20/15 kDa subunits; TAFII-20/TAFII-15; TAFII20/TAFII15Homo sapiens (human)
Transcription initiation factor TFIID subunit 9RNA polymerase II TBP-associated factor subunit G; STAF31/32; Transcription initiation factor TFIID 31 kDa subunit; TAFII-31; TAFII31; Transcription initiation factor TFIID 32 kDa subunit; TAFII-32; TAFII32Homo sapiens (human)
Male-specific lethal 1 homologMSL-1; Male-specific lethal 1-like 1; MSL1-like 1; Male-specific lethal-1 homolog 1Homo sapiens (human)
KAT8 regulatory NSL complex subunit 1MLL1/MLL complex subunit KANSL1; MSL1 homolog 1; hMSL1v1; NSL complex protein NSL1; Non-specific lethal 1 homologHomo sapiens (human)
Transcriptional adapter 2-betaADA2-like protein beta; ADA2-betaHomo sapiens (human)
ZZ-type zinc finger-containing protein 3Homo sapiens (human)
Transcription factor SPT20 homologp38-interacting protein; p38IPHomo sapiens (human)
SWI/SNF complex subunit SMARCC2BRG1-associated factor 170; BAF170; SWI/SNF complex 170 kDa subunit; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 2Homo sapiens (human)
Elongator complex protein 5Dermal papilla-derived protein 6; S-phase 2 proteinHomo sapiens (human)
SWI/SNF complex subunit SMARCC1BRG1-associated factor 155; BAF155; SWI/SNF complex 155 kDa subunit; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily C member 1Homo sapiens (human)
PHD finger protein 21ABHC80a; BRAF35-HDAC complex protein BHC80Homo sapiens (human)
Transcriptional adapter 1SPT3-associated factor 42; STAF42; Transcriptional adapter 1-like proteinHomo sapiens (human)
Elongator complex protein 4hELP4; PAX6 neighbor gene proteinHomo sapiens (human)
Microspherule protein 158 kDa microspherule protein; Cell cycle-regulated factor p78; INO80 complex subunit J; MCRS2Homo sapiens (human)
Enhancer of polycomb homolog 1Homo sapiens (human)
Cysteine-rich protein 2-binding proteinCSRP2-binding protein; ADA2A-containing complex subunit 2; ATAC2; CRP2-binding partner; CRP2BP; Lysine acetyltransferase 14Homo sapiens (human)
KAT8 regulatory NSL complex subunit 2NSL complex protein NSL2; Non-specific lethal 2 homologHomo sapiens (human)
Elongator complex protein 3hELP3; Protein lysine acetyltransferase ELP3; 2.3.1.-; tRNA uridine(34) acetyltransferase; 2.3.1.-Homo sapiens (human)
Chromatin modification-related protein MEAF6MYST/Esa1-associated factor 6; Esa1-associated factor 6 homolog; Protein EAF6 homolog; hEAF6; Sarcoma antigen NY-SAR-91Homo sapiens (human)
Histone deacetylase complex subunit SAP30LHCV non-structural protein 4A-transactivated protein 2; Sin3 corepressor complex subunit SAP30L; Sin3-associated protein p30-likeHomo sapiens (human)
E3 ubiquitin-protein ligase MSL2EC 2.3.2.-; E3 ubiquitin-protein transferase MSL2; Male-specific lethal 2-like 1; MSL2-like 1; Male-specific lethal-2 homolog; MSL-2; Male-specific lethal-2 homolog 1; RING finger protein 184Homo sapiens (human)
Breast cancer metastasis-suppressor 1Homo sapiens (human)
Transcription and mRNA export factor ENY2Enhancer of yellow 2 transcription factor homologHomo sapiens (human)
DNA methyltransferase 1-associated protein 1DNMAP1; DNMT1-associated protein 1Homo sapiens (human)
Coordinator of PRMT5 and differentiation stimulatorCooperator of PRMT5; Protein TTP1Homo sapiens (human)
MAP3K12-binding inhibitory protein 1MAPK upstream kinase-binding inhibitory protein; MUK-binding inhibitory proteinHomo sapiens (human)
MRG/MORF4L-binding proteinMRG-binding protein; Up-regulated in colon cancer 4; Urcc4Homo sapiens (human)
Inhibitor of growth protein 3p47ING3Homo sapiens (human)
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily E member 1-relatedSMARCE1-related protein; BRCA2-associated factor 35; HMG box-containing protein 20B; HMG domain-containing protein 2; HMG domain-containing protein HMGX2; Sox-like transcriptional factor; Structural DNA-binding protein BRAF35Homo sapiens (human)
KAT8 regulatory NSL complex subunit 3NSL complex protein NSL3; Non-specific lethal 3 homolog; Serum inhibited-related protein; Testis development protein PRTDHomo sapiens (human)
Transformation/transcription domain-associated protein350/400 kDa PCAF-associated factor; PAF350/400; STAF40; Tra1 homologHomo sapiens (human)

Compounds (13)

CompoundDescription
Succinate
ammonium hydroxideThe hydroxy salt of ammonium ion. It is formed when AMMONIA reacts with water molecules in solution.
CalciumA basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes.
Carbon DioxideA colorless, odorless gas that can be formed by the body and is necessary for the respiration cycle of plants and animals.
adenosine diphosphateAdenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position.
formaldehydeA highly reactive aldehyde gas formed by oxidation or incomplete combustion of hydrocarbons. In solution, it has a wide range of uses: in the manufacture of resins and textiles, as a disinfectant, and as a laboratory fixative or preservative. Formaldehyde solution (formalin) is considered a hazardous compound, and its vapor toxic. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p717)
WaterA clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed)
OxygenAn element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration.
alpha-Ketoglutarate
adenosine triphosphateAn adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter.
s-adenosylmethioninePhysiologic methyl radical donor involved in enzymatic transmethylation reactions and present in all living organisms. It possesses anti-inflammatory activity and has been used in treatment of chronic liver disease. (From Merck, 11th ed)
Coenzyme A
Acetyl Coenzyme AAcetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent.