Page last updated: 2024-10-06

Bumetanide Action Pathway

Proteins (31)

ProteinSynonymsTaxonomy
Solute carrier family 12 member 3Na-Cl cotransporter; NCC; Na-Cl symporter; Thiazide-sensitive sodium-chloride cotransporterHomo sapiens (human)
Mineralocorticoid receptor MR; Nuclear receptor subfamily 3 group C member 2Homo sapiens (human)
Solute carrier family 22 member 6Organic anion transporter 1; hOAT1; PAH transporter; hPAHT; Renal organic anion transporter 1; hROAT1Homo sapiens (human)
Large neutral amino acids transporter small subunit 2L-type amino acid transporter 2; hLAT2; Solute carrier family 7 member 8Homo sapiens (human)
Sodium/potassium-transporting ATPase subunit beta-1Sodium/potassium-dependent ATPase subunit beta-1Homo sapiens (human)
Excitatory amino acid transporter 3Excitatory amino-acid carrier 1; Neuronal and epithelial glutamate transporter; Sodium-dependent glutamate/aspartate transporter 3; Solute carrier family 1 member 1Homo sapiens (human)
Large neutral amino acids transporter small subunit 14F2 light chain; 4F2 LC; 4F2LC; CD98 light chain; Integral membrane protein E16; E16; L-type amino acid transporter 1; hLAT1; Solute carrier family 7 member 5; y+ system cationic amino acid transporterHomo sapiens (human)
Sodium/potassium-transporting ATPase subunit alpha-4Na(+)/K(+) ATPase alpha-4 subunit; EC 7.2.2.13; Sodium pump subunit alpha-4Homo sapiens (human)
Solute carrier family 22 member 2Organic cation transporter 2; hOCT2Homo sapiens (human)
Sodium/potassium-transporting ATPase subunit alpha-1 Na(+)/K(+) ATPase alpha-1 subunit; EC 7.2.2.13; Sodium pump subunit alpha-1Homo sapiens (human)
Sodium/potassium-transporting ATPase subunit alpha-3Na(+)/K(+) ATPase alpha-3 subunit; EC 7.2.2.13; Na(+)/K(+) ATPase alpha(III) subunit; Sodium pump subunit alpha-3Homo sapiens (human)
Sodium/potassium-transporting ATPase subunit beta-2Adhesion molecule in glia; AMOG; Sodium/potassium-dependent ATPase subunit beta-2Homo sapiens (human)
Amiloride-sensitive sodium channel subunit alphaAlpha-NaCH; Epithelial Na(+) channel subunit alpha; Alpha-ENaC; ENaCA; Nonvoltage-gated sodium channel 1 subunit alpha; SCNEAHomo sapiens (human)
Sodium/potassium-transporting ATPase subunit alpha-2Na(+)/K(+) ATPase alpha-2 subunit; EC 7.2.2.13; Sodium pump subunit alpha-2Homo sapiens (human)
Amiloride-sensitive sodium channel subunit betaBeta-NaCH; Epithelial Na(+) channel subunit beta; Beta-ENaC; ENaCB; Nonvoltage-gated sodium channel 1 subunit beta; SCNEBHomo sapiens (human)
Amiloride-sensitive sodium channel subunit gammaEpithelial Na(+) channel subunit gamma; ENaCG; Gamma-ENaC; Gamma-NaCH; Nonvoltage-gated sodium channel 1 subunit gamma; SCNEGHomo sapiens (human)
Sodium/potassium-transporting ATPase subunit beta-3Sodium/potassium-dependent ATPase subunit beta-3; ATPB-3Homo sapiens (human)
Sodium/potassium-transporting ATPase subunit gammaNa(+)/K(+) ATPase subunit gamma; FXYD domain-containing ion transport regulator 2; Sodium pump gamma chainHomo sapiens (human)
4F2 cell-surface antigen heavy chain4F2hc; 4F2 heavy chain antigen; Lymphocyte activation antigen 4F2 large subunit; Solute carrier family 3 member 2Homo sapiens (human)
Amiloride-sensitive sodium channel subunit deltaDelta-NaCH; Epithelial Na(+) channel subunit delta; Delta-ENaC; ENaCD; Nonvoltage-gated sodium channel 1 subunit delta; SCNEDHomo sapiens (human)
Chloride channel protein ClC-KaChloride channel Ka; ClC-K1Homo sapiens (human)
b(0,+)-type amino acid transporter 1b(0,+)AT1; Glycoprotein-associated amino acid transporter b0,+AT1; Solute carrier family 7 member 9Homo sapiens (human)
Neutral and basic amino acid transport protein rBATNBAT; D2h; Solute carrier family 3 member 1; b(0,+)-type amino acid transport proteinHomo sapiens (human)
Solute carrier family 12 member 1Bumetanide-sensitive sodium-(potassium)-chloride cotransporter 2; Kidney-specific Na-K-Cl symporterHomo sapiens (human)
Urea transporter 2Solute carrier family 14 member 2; Urea transporter, kidneyHomo sapiens (human)
Y+L amino acid transporter 2Cationic amino acid transporter, y+ system; Solute carrier family 7 member 6; y(+)L-type amino acid transporter 2; Y+LAT2; y+LAT-2Homo sapiens (human)
Sodium-coupled neutral amino acid transporter 4Amino acid transporter A3; Na(+)-coupled neutral amino acid transporter 4; Solute carrier family 38 member 4; System A amino acid transporter 3; System N amino acid transporter 3Homo sapiens (human)
Sodium- and chloride-dependent transporter XTRP3Sodium/imino-acid transporter 1; Solute carrier family 6 member 20; Transporter rB21A homologHomo sapiens (human)
Solute carrier family 12 member 6Electroneutral potassium-chloride cotransporter 3; K-Cl cotransporter 3Homo sapiens (human)
Y+L amino acid transporter 1Monocyte amino acid permease 2; MOP-2; Solute carrier family 7 member 7; y(+)L-type amino acid transporter 1; Y+LAT1; y+LAT-1Homo sapiens (human)
Sodium/potassium-transporting ATPase subunit betaHomo sapiens (human)

Compounds (8)

CompoundDescription
ureaA compound formed in the liver from ammonia produced by the deamination of amino acids. It is the principal end product of protein catabolism and constitutes about one half of the total urinary solids.
bumetanideA sulfamyl diuretic.
chlorineAn element with atomic symbol Cl, atomic number 17, and atomic weight 35, and member of the halogen family.
cysteineA thiol-containing non-essential amino acid that is oxidized to form CYSTINE.
hydrogen carbonate
potassiumAn element in the alkali group of metals with an atomic symbol K, atomic number 19, and atomic weight 39.10. It is the chief cation in the intracellular fluid of muscle and other cells. Potassium ion is a strong electrolyte that plays a significant role in the regulation of fluid volume and maintenance of the WATER-ELECTROLYTE BALANCE.
SodiumA member of the alkali group of metals. It has the atomic symbol Na, atomic number 11, and atomic weight 23.
ProlineA non-essential amino acid that is synthesized from GLUTAMIC ACID. It is an essential component of COLLAGEN and is important for proper functioning of joints and tendons.