Conditions > Brain Stem Hematoma, Traumatic
Page last updated: 2024-09-27

Brain Stem Hematoma, Traumatic

Bleeding into structures of BRAIN STEM, including the MIDBRAIN; PONS; or MEDULLA OBLONGATA, as the result of CRANIOCEREBRAL TRAUMA. DIFFUSE AXONAL INJURY is commonly associated. Clinical manifestations may include OCULAR MOTILITY DISORDERS; ATAXIA; PARALYSIS; PERSISTENT VEGETATIVE STATE; and COMA.

Synonyms(15)

Synonym
Midbrain Hemorrhage, Traumatic
Brainstem Hematoma, Traumatic
Traumatic Brain Stem Hemorrhage
Pontine Hemorrhage, Traumatic
Traumatic Brain Stem Hematoma
Post-Traumatic Brain Stem Hemorrhage
Brain Stem Hemorrhage, Traumatic
Hemorrhage, Brain Stem, Traumatic
Post-Traumatic Brainstem Hemorrhage
Traumatic Brainstem Hemorrhage
Brain Stem Hemorrhage, Post-Traumatic
Bulbar Hemorrhage, Traumatic
Brain Stem Hematoma, Traumatic
Medullary Hemorrhage, Traumatic
Brainstem Hemorrhage, Traumatic

Research

Studies (5)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's2 (40.00)18.1394
2010's3 (60.00)28.8240
2020's0 (0.00)9.53
DrugIndicatedRelationship StrengthStudiesTrials
deferoxamine0low10
barium sulfate0low10
fomesafen0low10
warfarin0low10
transforming growth factor beta0low10

Protein Targets (52)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
TDP1 protein1001
apical membrane antigen 1, AMA11001
67.9K protein1001
IDH11001
nuclear factor erythroid 2-related factor 2 isoform 21001
DNA polymerase iota isoform a (long)1001
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
geminin1001
Lysine-specific demethylase 4A0101
Guanine nucleotide-binding protein G1001
Hypoxia-inducible factor 1-alpha0011
Methylcytosine dioxygenase TET20101
Deoxyhypusine hydroxylase0101
Luciferase1001
hypoxia-inducible factor 1 alpha subunit1001
progesterone receptor2002
estrogen-related nuclear receptor alpha2002
pregnane X nuclear receptor2002
estrogen nuclear receptor alpha2002
peroxisome proliferator activated receptor gamma2002
vitamin D (1,25- dihydroxyvitamin D3) receptor1001
Histone H2A.x1001
nuclear factor erythroid 2-related factor 2 isoform 11001
Chain A, Beta-lactamase1001
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
Chain A, HADH2 protein1001
Chain B, HADH2 protein1001
Chain A, 2-oxoglutarate Oxygenase1001
RAR-related orphan receptor gamma1001
PPM1D protein1001
GLI family zinc finger 31001
aldehyde dehydrogenase 1 family, member A11001
EWS/FLI fusion protein1001
glucocorticoid receptor [Homo sapiens]1001
retinoic acid nuclear receptor alpha variant 11001
thyroid hormone receptor beta isoform a1001
parathyroid hormone/parathyroid hormone-related peptide receptor precursor1001
thyroid hormone receptor beta isoform 21001
Bile salt export pump0101
Interferon beta1001
Albumin0011
Albumin0011
Cellular tumor antigen p531001
Cytochrome P450 2C9 0101
Proprotein convertase subtilisin/kexin type 70101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 10101
Protease 0101
Vitamin K epoxide reductase complex subunit 1-like protein 10101
Vitamin K epoxide reductase complex subunit 1 0202
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]