Page last updated: 2024-11-05

terephthaloyl chloride

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

Terephthaloyl chloride is a white crystalline solid used in the production of polyester fibers and resins. It is synthesized through the reaction of terephthalic acid with thionyl chloride. Terephthaloyl chloride is a key intermediate in the production of polyethylene terephthalate (PET), a widely used plastic. The compound is also used in the synthesis of other polymers, pharmaceuticals, and dyes. Research into terephthaloyl chloride focuses on developing more efficient and sustainable production methods, exploring its applications in advanced materials, and investigating its environmental impact.'

terephthaloyl chloride: cross-links albumin [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID7488
CHEMBL ID1893301
SCHEMBL ID68148
MeSH IDM0166107

Synonyms (49)

Synonym
p-phenylenedicarbonyl dichloride
p-phthaloyl chloride
1,4-benzenedicarbonyl chloride
nsc-41885
terephthalyl dichloride
p-phthalyl dichloride
terephthalic dichloride
terephthalic acid dichloride
p-phthaloyl dichloride
terephthalic acid chloride
nsc41885
terephthaloyl chloride
100-20-9
terephthaloyl dichloride
1,4-benzenedicarbonyl dichloride
inchi=1/c8h4cl2o2/c9-7(11)5-1-2-6(4-3-5)8(10)12/h1-4
terephthaloyl chloride, >=99%, flakes
NCGC00164045-01
hsdb 5332
nsc 41885
einecs 202-829-5
brn 0607796
benzene-1,4-dicarbonyl chloride
T0017
NCGC00164045-02
g247co9608 ,
ec 202-829-5
unii-g247co9608
ccris 8626
4-09-00-03318 (beilstein handbook reference)
dtxcid506653
NCGC00257127-01
cas-100-20-9
tox21_303166
dtxsid7026653 ,
tox21_201899
NCGC00259448-01
AKOS015890038
benzene 1,4-dicarboxylic acid dichloride
SCHEMBL68148
terephthalic chloride
terephthaloylchloride
Q-201791
CHEMBL1893301
mfcd00000693
benzene-1,4-dicarbonyl dichloride
BCP27385
Q7702072
STR02815
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (7)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
LuciferasePhotinus pyralis (common eastern firefly)Potency51.65300.007215.758889.3584AID1224835
RAR-related orphan receptor gammaMus musculus (house mouse)Potency68.79890.006038.004119,952.5996AID1159521; AID1159523
glucocorticoid receptor [Homo sapiens]Homo sapiens (human)Potency0.01410.000214.376460.0339AID588532
farnesoid X nuclear receptorHomo sapiens (human)Potency0.00140.375827.485161.6524AID588527
peroxisome proliferator activated receptor gammaHomo sapiens (human)Potency31.62280.001019.414170.9645AID588536
thyroid stimulating hormone receptorHomo sapiens (human)Potency68.79890.001628.015177.1139AID1259385; AID1259395
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_aHomo sapiens (human)Potency61.652419.739145.978464.9432AID1159509
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (16)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (6.25)18.7374
1990's5 (31.25)18.2507
2000's7 (43.75)29.6817
2010's3 (18.75)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 52.66

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be very strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index52.66 (24.57)
Research Supply Index3.04 (2.92)
Research Growth Index5.04 (4.65)
Search Engine Demand Index78.34 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (52.66)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other20 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]