Page last updated: 2024-11-12

spinigerin

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

spinigerin: antimicrobial peptide isolated from the fungus-growing termite Pseudacanthotermes spiniger (heterometabole insect, Isoptera); GenBank P82357 [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID16209973
CHEMBL ID1240720
MeSH IDM0390463

Synonyms (3)

Synonym
hvdkkvadkvlllkqlrimrlltrl
spinigerin
CHEMBL1240720

Research Excerpts

Overview

Spinigerin is a linear antibacterial peptide derived from a termite insect.

ExcerptReferenceRelevance
"Spinigerin is a linear antibacterial peptide derived from a termite insect. "( Solution structure of termite-derived antimicrobial peptide, spinigerin, as determined in SDS micelle by NMR spectroscopy.
Hahm, KS; Hong, JE; Kim, JI; Kim, Y; Lee, KH; Shin, SY; Yang, ST, 2003
)
2

Actions

ExcerptReferenceRelevance
"Spinigerin displays good lytic activities against Gram-positive and Gram-negative bacteria, but has no hemolytic activities against human erythrocytes."( Solution structure of termite-derived antimicrobial peptide, spinigerin, as determined in SDS micelle by NMR spectroscopy.
Hahm, KS; Hong, JE; Kim, JI; Kim, Y; Lee, KH; Shin, SY; Yang, ST, 2003
)
1.28
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (3)

Assay IDTitleYearJournalArticle
AID511694Antiviral activity against HIV1 3B infected in human CEM-SS cells assessed as inhibition of viral replication after 6 days by XTT assay2010Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3
Identification of novel human immunodeficiency virus type 1-inhibitory peptides based on the antimicrobial peptide database.
AID511696Therapeutic index, ratio of TC50 for human CEM-SS cells infected with HIV1 3B to EC50 for HIV1 3B infected in human CEM-SS cells2010Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3
Identification of novel human immunodeficiency virus type 1-inhibitory peptides based on the antimicrobial peptide database.
AID511695Cytotoxicity against human CEM-SS cells infected with HIV1 3B after 6 days by XTT assay2010Antimicrobial agents and chemotherapy, Mar, Volume: 54, Issue:3
Identification of novel human immunodeficiency virus type 1-inhibitory peptides based on the antimicrobial peptide database.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's2 (40.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.50

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.50 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.30 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.50)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]