Page last updated: 2024-11-13

saf-m

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID Source	ID
PubMed CID	76972485
MeSH ID	M0152877

Synonyms (20)

Synonym
n-acetylmuramyl-threonyl-isoglutamine
drg-0177
threonyl mdp
temurtide [usan:inn:ban]
rs-37449
temurtidum [inn-latin]
temurtidum
saf-m
termurtide
temurtida [inn-spanish]
temurtida
2-acetamido-3-o-(((1r)-1-((1s,2r)-1-(((1r)-1-carbamoyl-3-carboxypropyl)carbamoyl)-2-hydroxypropyl)carbamoyl)ethyl)-2-deoxy-d-glucopyranose
unii-vxk0tnd2ry
vxk0tnd2ry ,
d-alpha-glutamine, n(sup 2)-(n-(n-acetylmuramoyl)-l-threonyl)-
temurtide [usan]
(4r)-4-((2s,3r)-2-((2r)-2-(((3r,4r,5s,6r)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2h-pyran-4-yl)oxy)propanamido)-3-hydroxybutanamido)-5-amino-5-oxopentanoic acid
(4r,5r,7r,10s,13r)-13-carbamoyl-4-formyl-10-((r)-1-hydroxyethyl)-7-methyl-2,8,11-trioxo-5-((1r,2r)-1,2,3-trihydroxypropyl)-6-oxa-3,9,12-triazahexadecan-16-oic acid
temurtide [inn]
Q27292071

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	3 (42.86)	18.7374
1990's	4 (57.14)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 28.10

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	28.10 (24.57)
Research Supply Index	2.20 (2.92)
Research Growth Index	4.51 (4.65)
Search Engine Demand Index	31.58 (26.88)
Search Engine Supply Index	2.00 (0.95)

This Compound (28.10)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	1 (14.29%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	6 (85.71%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
formaldehyde paraform: polymerized formaldehyde; RN given refers to parent cpd; used in root canal therapy	1.97	1	aldehyde; one-carbon compound	allergen; carcinogenic agent; disinfectant; EC 3.5.1.4 (amidase) inhibitor; environmental contaminant; Escherichia coli metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite
squalane [no description available]	1.97	1
poloxalene Poloxalene: A copolymer of polyethylene and polypropylene ether glycol. It is a non-ionic polyol surface-active agent used medically as a fecal softener and in cattle for prevention of bloat.. pluronic : A triblock copolymer composed of a central hydrophobic chain of poly(propylene oxide) flanked by two hydrophilic chains of poly(ethylene oxide).	1.97	1	epoxide
aluminum sulfate aluminium sulfate (anhydrous) : An aluminium sulfate that contains no water of crystallisation.	1.97	1	aluminium sulfate
6-o-stearoyl-n-acetylmuramyl-alanylisoglutamine [no description available]	1.97	1
squalene Addavax: an oil-water nanoemulsion and adjuvant containing squalene, Tween 80, and sorbitane trioleate	1.97	1	triterpene	human metabolite; mouse metabolite; plant metabolite; Saccharomyces cerevisiae metabolite

Condition	Relationship Strength	Studies	Trials
Innate Inflammatory Response [description not available]	1.98	1	0
Inflammation A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.	1.98	1	0
Necrosis The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.	1.98	1	0
Grippe [description not available]	1.99	1	0
Influenza, Human An acute viral infection in humans involving the respiratory tract. It is marked by inflammation of the NASAL MUCOSA; the PHARYNX; and conjunctiva, and by headache and severe, often generalized, myalgia.	1.99	1	0
Malignant Melanoma [description not available]	3.38	1	1
Melanoma A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)	8.38	1	1
Disease Models, Animal Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.	1.97	1	0
Infections, Retroviridae [description not available]	1.97	1	0
Retroviridae Infections Virus diseases caused by the RETROVIRIDAE.	1.97	1	0
Allergy, Drug [description not available]	1.97	1	0
Drug Hypersensitivity Immunologically mediated adverse reactions to medicinal substances used legally or illegally.	1.97	1	0

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