mintlactone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

mintlactone: isolated from Mentha cardiaca structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Flora	Rank	Flora Definition	Family	Family Definition
Mentha	genus	Mentha is a genus of the mint family (LAMIACEAE). It is known for species having characteristic flavor and aroma.[MeSH]	Lamiaceae	The mint plant family. They are characteristically aromatic, and many of them are cultivated for their oils. Most have square stems, opposite leaves, and two-lipped, open-mouthed, tubular corollas (united petals), with five-lobed, bell-like calyxes (united sepals).[MeSH]
Mentha cardiaca	species	[no description available]	Lamiaceae	The mint plant family. They are characteristically aromatic, and many of them are cultivated for their oils. Most have square stems, opposite leaves, and two-lipped, open-mouthed, tubular corollas (united petals), with five-lobed, bell-like calyxes (united sepals).[MeSH]

Cross-References

ID Source	ID
PubMed CID	642875
SCHEMBL ID	783669
MeSH ID	M0364825

Synonyms (25)

Synonym
2(4h)-benzofuranone, 5,6,7,7a-tetrahydro-3,6-dimethyl-, (6r,7ar)-
(6r,7ar)-3,6-dimethyl-5,6,7,7a-tetrahydro-1-benzofuran-2(4h)-one
inchi=1/c10h14o2/c1-6-3-4-8-7(2)10(11)12-9(8)5-6/h6,9h,3-5h2,1-2h3/t6-,9-/m1/s
menthalactone
mint lactone
einecs 236-390-6
fema no. 3764
mintlactone
(+/-)-mintlactone
38049-04-6
(-)-mintlactone
unii-x2t3i06cwr
x2t3i06cwr ,
2(4h)-benzofuranone, 5,6,7,7a-tetrahydro-3,6-dimethyl-, (6r-trans)-
mintlactone, (-)
mintlactone [fhfi]
SCHEMBL783669
VUVQBYIJRDUVHT-HZGVNTEJSA-N
(6r,7ar)-3,6-dimethyl-5,6,7,7a-tetrahydrobenzofuran-2(4h)-one
rtx0q4yj2u ,
2(4h)-benzofuranone, 5,6,7,7a-tetrahydro-3,6-dimethyl-, trans-
unii-rtx0q4yj2u
2(4h)-benzofuranone, 5,6,7,7a-tetrahydro-3,6-dimethyl-, trans-(+/-)-
16434-36-9
2(4h)-benzofuranone, 5,6,7,7a-tetrahydro-3,6-dimethyl-, (6r,7ar)-rel-

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	5 (71.43)	29.6817
2010's	0 (0.00)	24.3611
2020's	2 (28.57)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 36.32

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be strong demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	36.32 (24.57)
Research Supply Index	2.08 (2.92)
Research Growth Index	4.82 (4.65)
Search Engine Demand Index	28.17 (26.88)
Search Engine Supply Index	2.00 (0.95)

This Compound (36.32)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	7 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
menthol Menthol: A monoterpene cyclohexanol produced from mint oils.	2.31	1	p-menthane monoterpenoid; secondary alcohol	volatile oil component
eucalyptol [no description available]	2.31	1
piperitone piperitone: from Mentha longifolia var. chorodictya Rech F; structure in first source. piperitone : A p-menthane monoterpenoid that is cyclohex-2-en-1-one substituted by a methyl group at position 3 and an isopropyl group at position 6.	2.31	1	cyclic terpene ketone; p-menthane monoterpenoid	plant metabolite; volatile oil component
carvone carvone: an oxidized derivative of limonene; RN given refers to cpd without isomeric designation; L-carvone has spearmint flavor, D-carvone has dill/caraway flavor. carvone : A p-menthane monoterpenoid that consists of cyclohex-2-enone having methyl and isopropenyl substituents at positions 2 and 5, respectively.	2.31	1	botanical anti-fungal agent; carvones	allergen
gamma-collidine gamma-collidine: structure	2.05	1	methylpyridines
cyclohexanol Cyclohexanols: Monohydroxy derivatives of cyclohexanes that contain the general formula R-C6H11O. They have a camphorlike odor and are used in making soaps, insecticides, germicides, dry cleaning, and plasticizers.. cyclohexanols : An alcohol in which one or more hydroxy groups are attached to a cyclohexane skeleton.	2.05	1	cyclohexanols; secondary alcohol	solvent
propylene propylene: structure	2.05	1	alkene; gas molecular entity	refrigerant; xenobiotic
citronellol citronellol: alcohol form of citronellal; found in rose oil; RN given refers to parent cpd without isomeric designation; structure. citronellol : A monoterpenoid that is oct-6-ene substituted by a hydroxy group at position 1 and methyl groups at positions 3 and 7.. insect repellent : An insecticide that acts as a repellent to insects.	2.05	1	monoterpenoid	plant metabolite
propadiene [no description available]	2.05	1	allenes
limonene Limonene: A naturally-occurring class of MONOTERPENES which occur as a clear colorless liquid at room temperature. Limonene is the major component in the oil of oranges which has many uses, including as flavor and fragrance. It is recognized as safe in food by the Food and Drug Administration (FDA).. limonene : A monoterpene that is cyclohex-1-ene substituted by a methyl group at position 1 and a prop-1-en-2-yl group at position 4 respectively.	2.31	1	cycloalkene; p-menthadiene	human metabolite
molybdenum Molybdenum: A metallic element with the atomic symbol Mo, atomic number 42, and atomic weight 95.95. It is an essential trace element, being a component of the enzymes xanthine oxidase, aldehyde oxidase, and nitrate reductase.	2.05	1	chromium group element atom	micronutrient
ruthenium Ruthenium: A hard, brittle, grayish-white rare earth metal with an atomic symbol Ru, atomic number 44, and atomic weight 101.07. It is used as a catalyst and hardener for PLATINUM and PALLADIUM.	7.05	1	iron group element atom; platinum group metal atom
nitrous acid Nitrous Acid: Nitrous acid (HNO2). A weak acid that exists only in solution. It can form water-soluble nitrites and stable esters. (From Merck Index, 11th ed)	2.05	1	nitrogen oxoacid
menthone menthone : The trans-stereoisomer of p-menthan-3-one.. (-)-menthone : A menthone that is cyclohexanone substituted by a methyl and an isopropyl group at positions 5 and 2 respectively (the 2S,5R-stereoisomer).	2.31	1	menthone
alkenes [no description available]	2.05	1
allenolic acid allenolic acid: structure in first source	2.04	1	naphthols
isopulegol isopulegol: isolated from Mentha cardiaca structure in first source	7	1	p-menthane monoterpenoid	metabolite
pulegone pulegone: component of peppermint oil; RN given refers to cpd without isomeric designation; structure in Merck. (+)-pulegone : The (5R)-enantiomer of p-menth-4(8)-en-3-one.	2.48	2	p-menth-4(8)-en-3-one
thallium Thallium: A heavy, bluish white metal, atomic number 81, atomic weight [204.382; 204.385], symbol Tl.. thallium : A metallic element first identified and named from the brilliant green line in its flame spectrum (from Greek thetaalphalambdalambdaomicronsigma, a green shoot).	7	1	boron group element atom

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