Page last updated: 2024-11-13

micropyrone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

micropyrone: from Helichrysum italicum ssp. microphyllum; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

FloraRankFlora DefinitionFamilyFamily Definition
HelichrysumgenusA plant genus of the family ASTERACEAE. Members contain CHALCONE, helichrysetin, arenarin, and flamin.[MeSH]AsteraceaeA large plant family of the order Asterales, subclass Asteridae, class Magnoliopsida. The family is also known as Compositae. Flower petals are joined near the base and stamens alternate with the corolla lobes. The common name of daisy refers to several genera of this family including Aster; CHRYSANTHEMUM; RUDBECKIA; TANACETUM.[MeSH]
Helichrysum italicumspecies[no description available]AsteraceaeA large plant family of the order Asterales, subclass Asteridae, class Magnoliopsida. The family is also known as Compositae. Flower petals are joined near the base and stamens alternate with the corolla lobes. The common name of daisy refers to several genera of this family including Aster; CHRYSANTHEMUM; RUDBECKIA; TANACETUM.[MeSH]

Cross-References

ID SourceID
PubMed CID54682570
CHEMBL ID390585
MeSH IDM0579248

Synonyms (2)

Synonym
micropyrone
CHEMBL390585
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (7)

Assay IDTitleYearJournalArticle
AID283731Inhibition of TNFalpha activated NF-kappaB dependent transactivation of HIV-1 LTR Luc in 5.1 cells2007Journal of natural products, Apr, Volume: 70, Issue:4
Arzanol, an anti-inflammatory and anti-HIV-1 phloroglucinol alpha-Pyrone from Helichrysum italicum ssp. microphyllum.
AID736330Antibacterial activity against Staphylococcus aureus XU212 overexpressing TetK tetracycline efflux pump after 18 hrs by MTT assay2013Journal of natural products, Mar-22, Volume: 76, Issue:3
Antimicrobial phenolics and unusual glycerides from Helichrysum italicum subsp. microphyllum.
AID736331Antibacterial activity against Staphylococcus aureus 1199B overexpressing NorA pump after 18 hrs by MTT assay2013Journal of natural products, Mar-22, Volume: 76, Issue:3
Antimicrobial phenolics and unusual glycerides from Helichrysum italicum subsp. microphyllum.
AID736327Antibacterial activity against epidemic methicillin-resistant Staphylococcus aureus EMRSA-15 after 18 hrs by MTT assay2013Journal of natural products, Mar-22, Volume: 76, Issue:3
Antimicrobial phenolics and unusual glycerides from Helichrysum italicum subsp. microphyllum.
AID736329Antibacterial activity against Staphylococcus aureus ATCC 25923 after 18 hrs by MTT assay2013Journal of natural products, Mar-22, Volume: 76, Issue:3
Antimicrobial phenolics and unusual glycerides from Helichrysum italicum subsp. microphyllum.
AID736328Antibacterial activity against Staphylococcus aureus RN4220 overexpressing MsrA macrolide efflux protein after 18 hrs by MTT assay2013Journal of natural products, Mar-22, Volume: 76, Issue:3
Antimicrobial phenolics and unusual glycerides from Helichrysum italicum subsp. microphyllum.
AID736326Antibacterial activity against epidemic methicillin-resistant Staphylococcus aureus EMRSA-16 after 18 hrs by MTT assay2013Journal of natural products, Mar-22, Volume: 76, Issue:3
Antimicrobial phenolics and unusual glycerides from Helichrysum italicum subsp. microphyllum.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 13.20

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index13.20 (24.57)
Research Supply Index1.79 (2.92)
Research Growth Index4.99 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (13.20)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other5 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]