Page last updated: 2024-11-13
micropyrone
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
micropyrone: from Helichrysum italicum ssp. microphyllum; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Related Flora
| Flora | Rank | Flora Definition | Family | Family Definition |
|---|---|---|---|---|
| Helichrysum | genus | A plant genus of the family ASTERACEAE. Members contain CHALCONE, helichrysetin, arenarin, and flamin.[MeSH] | Asteraceae | A large plant family of the order Asterales, subclass Asteridae, class Magnoliopsida. The family is also known as Compositae. Flower petals are joined near the base and stamens alternate with the corolla lobes. The common name of daisy refers to several genera of this family including Aster; CHRYSANTHEMUM; RUDBECKIA; TANACETUM.[MeSH] |
| Helichrysum italicum | species | [no description available] | Asteraceae | A large plant family of the order Asterales, subclass Asteridae, class Magnoliopsida. The family is also known as Compositae. Flower petals are joined near the base and stamens alternate with the corolla lobes. The common name of daisy refers to several genera of this family including Aster; CHRYSANTHEMUM; RUDBECKIA; TANACETUM.[MeSH] |
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 54682570 |
| CHEMBL ID | 390585 |
| MeSH ID | M0579248 |
Synonyms (2)
| Synonym |
|---|
| micropyrone |
| CHEMBL390585 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (7)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID283731 | Inhibition of TNFalpha activated NF-kappaB dependent transactivation of HIV-1 LTR Luc in 5.1 cells | 2007 | Journal of natural products, Apr, Volume: 70, Issue:4 | Arzanol, an anti-inflammatory and anti-HIV-1 phloroglucinol alpha-Pyrone from Helichrysum italicum ssp. microphyllum. |
| AID736330 | Antibacterial activity against Staphylococcus aureus XU212 overexpressing TetK tetracycline efflux pump after 18 hrs by MTT assay | 2013 | Journal of natural products, Mar-22, Volume: 76, Issue:3 | Antimicrobial phenolics and unusual glycerides from Helichrysum italicum subsp. microphyllum. |
| AID736331 | Antibacterial activity against Staphylococcus aureus 1199B overexpressing NorA pump after 18 hrs by MTT assay | 2013 | Journal of natural products, Mar-22, Volume: 76, Issue:3 | Antimicrobial phenolics and unusual glycerides from Helichrysum italicum subsp. microphyllum. |
| AID736327 | Antibacterial activity against epidemic methicillin-resistant Staphylococcus aureus EMRSA-15 after 18 hrs by MTT assay | 2013 | Journal of natural products, Mar-22, Volume: 76, Issue:3 | Antimicrobial phenolics and unusual glycerides from Helichrysum italicum subsp. microphyllum. |
| AID736329 | Antibacterial activity against Staphylococcus aureus ATCC 25923 after 18 hrs by MTT assay | 2013 | Journal of natural products, Mar-22, Volume: 76, Issue:3 | Antimicrobial phenolics and unusual glycerides from Helichrysum italicum subsp. microphyllum. |
| AID736328 | Antibacterial activity against Staphylococcus aureus RN4220 overexpressing MsrA macrolide efflux protein after 18 hrs by MTT assay | 2013 | Journal of natural products, Mar-22, Volume: 76, Issue:3 | Antimicrobial phenolics and unusual glycerides from Helichrysum italicum subsp. microphyllum. |
| AID736326 | Antibacterial activity against epidemic methicillin-resistant Staphylococcus aureus EMRSA-16 after 18 hrs by MTT assay | 2013 | Journal of natural products, Mar-22, Volume: 76, Issue:3 | Antimicrobial phenolics and unusual glycerides from Helichrysum italicum subsp. microphyllum. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (5)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 13.20
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (13.20) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||