| Assay ID | Title | Year | Journal | Article |
|---|
| AID1346987 | P-glycoprotein substrates identified in KB-8-5-11 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1296008 | Cytotoxic Profiling of Annotated Libraries Using Quantitative High-Throughput Screening | 2020 | SLAS discovery : advancing life sciences R & D, 01, Volume: 25, Issue:1
| Cytotoxic Profiling of Annotated and Diverse Chemical Libraries Using Quantitative High-Throughput Screening. |
| AID1347159 | Primary screen GU Rhodamine qHTS for Zika virus inhibitors: Unlinked NS2B-NS3 protease assay | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1347160 | Primary screen NINDS Rhodamine qHTS for Zika virus inhibitors | 2020 | Proceedings of the National Academy of Sciences of the United States of America, 12-08, Volume: 117, Issue:49
| Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors. |
| AID1346986 | P-glycoprotein substrates identified in KB-3-1 adenocarcinoma cell line, qHTS therapeutic library screen | 2019 | Molecular pharmacology, 11, Volume: 96, Issue:5
| A High-Throughput Screen of a Library of Therapeutics Identifies Cytotoxic Substrates of P-glycoprotein. |
| AID1474766 | Displacement of [3H]NMS from wild-type human mAChR2 expressed in Flp-in-CHO cell membranes in presence of mAChR2 agonist xanomeline after 90 mins by scintillation counting analysis | 2017 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 27, Issue:11
| Pharmacological property optimization for allosteric ligands: A medicinal chemistry perspective. |
| AID1474765 | Displacement of [3H]NMS from wild-type human mAChR2 expressed in Flp-In-CHO cell membranes in presence of mAChR2 agonist acetylcholine after 90 mins by scintillation counting analysis | 2017 | Bioorganic & medicinal chemistry letters, 06-01, Volume: 27, Issue:11
| Pharmacological property optimization for allosteric ligands: A medicinal chemistry perspective. |
| AID1513640 | Positive allosteric modulation of human M4 AchR expressed in CHO cells assessed as increase in acteylcholine-induced calcium mobilization by FLIPR assay | 2019 | Journal of medicinal chemistry, 01-10, Volume: 62, Issue:1
| Allosteric Modulation of Class A GPCRs: Targets, Agents, and Emerging Concepts. |
| AID1366204 | Positive allosteric modulation of rat M4 receptor expressed in CHO cells co-expressing Gqi5 assessed as increase in acetylcholine-induced calcium mobilization | 2017 | Bioorganic & medicinal chemistry letters, 11-15, Volume: 27, Issue:22
| Discovery of a novel 2,4-dimethylquinoline-6-carboxamide M |
| AID1345465 | Human M4 receptor (Acetylcholine receptors (muscarinic)) | 2008 | Proceedings of the National Academy of Sciences of the United States of America, Aug-05, Volume: 105, Issue:31
| Allosteric modulation of the muscarinic M4 receptor as an approach to treating schizophrenia. |
| AID1345326 | Human M2 receptor (Acetylcholine receptors (muscarinic)) | 2012 | Molecular pharmacology, Jan, Volume: 81, Issue:1
| Probe dependence in the allosteric modulation of a G protein-coupled receptor: implications for detection and validation of allosteric ligand effects. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |