| Trial | Phase | Enrollment | Study Type | Start Date | Status |
|---|
| [NCT01315093] | Phase 2/Phase 3 | 50 participants (Actual) | Interventional | 2010-11-30 | Completed |
| Comparison of Slow Efficiency Daily Dialysis (SLEDD) With Unfractionated Heparin Versus Citrasate in Critically Ill Patients. [NCT01228292] | Phase 4 | 250 participants (Anticipated) | Interventional | 2011-01-31 | Not yet recruiting |
| Placement of Covered Stents to Treat Hemodialysis Access Stenosis in the Cephalic Arch and Central Veins [NCT01200914] | | 14 participants (Actual) | Interventional | 2011-01-31 | Terminated(stopped due to poor recruitment) |
| A Prospective Randomized Pilot Trial on Safety and Feasibility of Argatroban as Anticoagulant in Patients With Extracorporeal Membrane Oxygenation (ECMO) [NCT05226442] | Phase 2/Phase 3 | 40 participants (Anticipated) | Interventional | 2021-12-01 | Recruiting |
| A Randomized Controlled Crossover Trial of Two Different Central Venous Catheter Flushing Schemes in Pediatric Hematology and Oncology Patients in Alberta, Canada [NCT01343680] | Phase 3 | 2 participants (Actual) | Interventional | 2011-04-30 | Terminated(stopped due to Poor patient accrual) |
| [NCT01072955] | Phase 3 | 104 participants (Anticipated) | Interventional | 2010-04-30 | Recruiting |
| Efficacy and Safety of Alternating Systemic and Hepatic Artery Infusion Therapy Versus Systemic Chemotherapy Alone As Adjuvant Treatment After Resection of Liver Metastases From Colorectal Cancer: A Randomized, Parallel-Group, Open-Labelled, Active-Contro [NCT02529774] | Phase 2/Phase 3 | 432 participants (Anticipated) | Interventional | 2015-09-30 | Not yet recruiting |
| Heparin Intraoperative Instillation for Lower Urinary Tract Symptoms After Benign Hysterectomy: A Randomized Controlled Trial [NCT03633994] | Phase 2 | 104 participants (Anticipated) | Interventional | 2018-08-20 | Recruiting |
| the Effect of Unfractionated Heparin in Treatment of IVF-ET Failure [NCT01214772] | Phase 4 | 86 participants (Actual) | Interventional | 2009-05-31 | Completed |
| Evaluation of Maintenance Dosing vs Loading Dosing Upon Restarting Warfarin Therapy: A Prospective Randomized Trial. [NCT01124058] | Phase 1 | 39 participants (Actual) | Interventional | 2010-07-31 | Completed |
| HepZero:Heparin Free Dialysis With Evodial: A Prospective Multicenter, Open, Randomized, Controlled Clinical Study With Parallel Groups [NCT01318486] | | 265 participants (Actual) | Interventional | 2011-03-31 | Completed |
| Randomized Control Trial of Unfractionated Heparin Thromboprophylaxis Dosing for Antepartum Hospitalizations [NCT04635839] | Phase 4 | 46 participants (Actual) | Interventional | 2020-12-15 | Completed |
| Heparin Dose Reduction During Hemodialysis With the Gambro Revaclear and Revaclear MAX Hemodialyzers: Pilot Study I and II [NCT01181544] | | 5 participants (Actual) | Interventional | 2011-03-31 | Completed |
| Bladder Capacity as an Objective Measure of Response to Intravesical Treatment of Newly Diagnosed Interstitial Cystitis: a Prospective, Randomized Trial [NCT05223244] | Phase 4 | 83 participants (Actual) | Interventional | 2011-10-01 | Completed |
| A Phase 2/3 Study to Evaluate the Safety and Efficacy of Dociparstat Sodium for the Treatment of Severe COVID-19 in Adults at High Risk of Respiratory Failure [NCT04389840] | Phase 2/Phase 3 | 27 participants (Actual) | Interventional | 2020-07-08 | Terminated(stopped due to Due to improvement in the Coronavirus Disease 2019 (COVID-19) pandemic and low subject accrual.) |
| Single Center Open Label Randomized Study Evaluating Safety and Efficacy of Subcutaneous Heparin Compared to Standard of Care Intravenous Heparin Anticoagulation During Veno-venous Extracorporeal Membrane Oxygenation for Respiratory Failure [NCT04496362] | Phase 4 | 100 participants (Anticipated) | Interventional | 2018-10-10 | Recruiting |
| Standard-dose Apixaban AFtEr Very Low-dose ThromboLYSis for Acute Intermediate-high Risk Acute Pulmonary Embolism [NCT03988842] | Phase 4 | 4 participants (Actual) | Interventional | 2019-07-25 | Terminated(stopped due to COVID-19 pandemic) |
| Standard vs High Dose of Unfractionated Heparin in the Incidence of Radial Artery Occlusion (DEFINITION) Trial. [NCT04561648] | | 1,988 participants (Anticipated) | Interventional | 2020-08-01 | Recruiting |
| Tissue Plasminogen Activator Dwells to Reduce Catheter-associated Thrombosis and Infection [NCT03672006] | Phase 2 | 20 participants (Actual) | Interventional | 2019-04-22 | Completed |
| A Randomized Controlled Trial for PREvention of VENous ThromboEmbolism Following Radical Prostatectomy (PREVENTER Trial) [NCT03006562] | Phase 4 | 501 participants (Actual) | Interventional | 2017-07-01 | Terminated(stopped due to Early stopping point based on 2nd interim analysis (planned per protocol)) |
| Comparison of the Effecta and Drawbacks of Heparin Versus Hirudin Drugs in Haemodialysis Patients in Assiut University Hospitals [NCT06112262] | Early Phase 1 | 98 participants (Anticipated) | Interventional | 2023-12-20 | Not yet recruiting |
| Efficacy of a Single Dose Intravenous Heparin During Diagnostic Angiography in Reducing Sheath-clot Formation: A Randomized Controlled Trial [NCT01260519] | Phase 3 | 304 participants (Actual) | Interventional | 2008-07-31 | Completed |
| Normal Saline Versus Heparin Intermittent Flushing for the Prevention of Occlusion in Port-a-Cath: Randomized Controlled Trial [NCT05707936] | | 192 participants (Anticipated) | Interventional | 2023-02-01 | Not yet recruiting |
| Systemic Anticoagulation With Full Dose Low Molecular Weight Heparin (LMWH) Vs. Prophylactic or Intermediate Dose LMWH in High Risk COVID-19 Patients (HEP-COVID Trial) [NCT04401293] | Phase 3 | 257 participants (Actual) | Interventional | 2020-04-26 | Completed |
| Comparison of Unfractionated Heparin and Bivalirudin for Percutaneous Coronary Intervention for Stable Angina, Unstable Angina, and Non-ST Segment Elevation Myocardial Infarction [NCT02448550] | Phase 3 | 250 participants (Actual) | Interventional | 2015-05-31 | Terminated |
| Effect of Low-Molecular-Weight-Heparin (LMWH) on Pregnancy Outcome in Women With Multiple Failures of IVF-ET [NCT03701750] | Phase 4 | 240 participants (Anticipated) | Interventional | 2018-11-01 | Recruiting |
| A Comparison of Dilute Unfractionated Heparin and Standard Concentrated Unfractionated Heparin Protocols for Anticoagulation of the Extra-corporeal Circuit During Continuous Renal Replacement Therapy in the ICU [NCT01318811] | Phase 4 | 12 participants (Actual) | Interventional | 2011-03-31 | Terminated(stopped due to lack of recruitment) |
| Reprometabolic Syndrome Mediates Subfertility in Obesity [NCT02653092] | | 84 participants (Actual) | Interventional | 2016-06-30 | Completed |
| Prospective Observational Study of the Direct Oral Anticoagulants Periprocedural Management [NCT03182218] | | 1,100 participants (Actual) | Observational | 2015-02-28 | Completed |
| Performance and Safety of the Roxwood CenterCross™ CenterCross™ Ultra, CenterCross™ Ultra LV and MultiCross™ Catheters and MicroCross™ MicroCatheter in Native Coronary and Peripheral Arteries With a Stenotic Lesion or Chronic Total Occlusion (CTO) [NCT04059536] | | 0 participants (Actual) | Observational | 2019-10-31 | Withdrawn(stopped due to Sponsor decision) |
| Intravenous Heparin as an Adjunct for the Treatment of Anaphylactic/Anaphylactoid Reactions in the Emergency Department [NCT00657228] | | 0 participants (Actual) | Interventional | 2009-12-31 | Withdrawn(stopped due to Study did not start.) |
| Low Molecular Weight Heparin (Enoxaparin Sodium) and Standard Unfractionated Heparin for Hemodialysis Anticoagulation [NCT01356615] | | 27 participants (Actual) | Interventional | 2011-03-31 | Completed |
| A Three-arm, Multicenter, Open-label Randomized Controlled Trial of Hydroxychloroquine and Low-dose Prednisone on Recurrent Spontaneous Abortion With Undifferentiated Connective Tissue Diseases: Protocol for the Immunosuppressant Regimens for Living FEtus [NCT03671174] | | 420 participants (Anticipated) | Interventional | 2019-08-02 | Recruiting |
| Bivalirudin With Prolonged Full Dose Infusion Versus Heparin Alone During: a Multicenter, Randomized, Open-label Trial [NCT03822975] | | 6,016 participants (Actual) | Interventional | 2019-02-14 | Active, not recruiting |
| An Open-label, Randomised, Parallel-group, Multicentre, Observational Trial to Evaluate Safety and Efficacy of Edoxaban Tosylate in Children From 38 Weeks Gestational Age to Less Than 18 Years of Age With Cardiac Diseases at Risk of Thromboembolic Events [NCT03395639] | Phase 3 | 168 participants (Actual) | Interventional | 2018-05-15 | Completed |
| Comparison of Biocompatibility of Plasmapheresis Procedures With Citrate and Heparin Anticoagulation [NCT05191290] | Phase 4 | 15 participants (Actual) | Interventional | 2022-01-21 | Completed |
| Low Molecular Weight hEparin vs. Aspirin Post-partum [NCT05058924] | | 50 participants (Anticipated) | Interventional | 2021-08-29 | Recruiting |
| A Prospective, Randomized, Open Label, Multi-center Study of the Safety and Pharmacokinetics of Apixaban Versus Vitamin K Antagonist or LMWH in Pediatric Subjects With Congenital or Acquired Heart Disease Requiring Chronic Anticoagulation for Thromboembol [NCT02981472] | Phase 2 | 192 participants (Actual) | Interventional | 2017-01-19 | Completed |
| Low-Dose Tenecteplase in Covid-19 Patients With Acute Pulmonary Embolism: A Randomized, Double-Blind, Placebo-Controlled Trial [NCT04558125] | Phase 4 | 2 participants (Actual) | Interventional | 2020-09-08 | Terminated(stopped due to Identification of eligible patients was slower than anticipated.) |
| Routine Versus Selective Protamine Administration to Reduce Bleeding Complications After Transcatheter Aortic Valve Implantation [NCT05774691] | Phase 4 | 1,000 participants (Anticipated) | Interventional | 2023-11-01 | Recruiting |
| Safety and Efficacy of Switching From Direct Oral Anticoagulants to Low Molecular Weight Heparin in Cancer Patients With Atrial Fibrillation During Antineoplastic Therapy [NCT04508855] | | 240 participants (Anticipated) | Observational | 2020-08-01 | Recruiting |
| Postprandial Fatty Acid Metabolism in Subjects With Lipoprotein Lipase Deficiency [NCT04227678] | | 16 participants (Anticipated) | Interventional | 2019-12-09 | Recruiting |
| Randomized Control Trial to Assessed the Impact of Low Dose Unfractionated Heparin Treatment on Inflammation in Severe Sepsis [NCT02135770] | Phase 3 | 115 participants (Actual) | Interventional | 2013-01-31 | Completed |
| A Randomized, Open-Label Trial of Therapeutic Anticoagulation in COVID-19 Patients With an Elevated D-Dimer [NCT04377997] | Phase 2 | 300 participants (Anticipated) | Interventional | 2020-05-15 | Recruiting |
| Study of Clinical Non-inferiority of Actparin® (Laboratorio Bergamo) Compared to Heparin Sodium (APP Pharmaceuticals), in Patients With Chronic Renal Failure [NCT01346215] | Phase 3 | 132 participants (Anticipated) | Interventional | 2011-10-31 | Not yet recruiting |
| Randomized Controlled Trial of Intermittent Hemodialysis With Regional Citrate Anticoagulation Versus Systemic Low Dose Heparin Anticoagulation in Patients at Risk of Bleeding in Nephrology Intensive Care Unit [NCT03562754] | | 60 participants (Actual) | Interventional | 2019-03-11 | Completed |
| Anticoagulant Effect and Reversal of Hepalean Compared With PPC Heparin in Patients Undergoing Cardiopulmonary Bypass: a Pilot Randomized Trial [NCT01343381] | Phase 4 | 21 participants (Actual) | Interventional | 2011-06-30 | Completed |
| A Phase III, Non-inferiority, Randomized, Double-blind Trial Comparing Eurofarma Unfractionated Sodium Heparin 5,000 IU to APP Pharmaceuticals Unfractionated Sodium Heparin 5,000 IU in the Thromboprophylaxis of Geriatric Patients Who Underwent Hip Fractur [NCT01352039] | Phase 3 | 544 participants (Actual) | Interventional | 2011-10-31 | Terminated |
| High Bolus Dose Tirofiban and Enoxaparin Provides Reduced Thrombin Generation and Inflammatory Markers in Patients With High Risk Undergoing Percutaneous Intervention [NCT00790387] | Phase 4 | 60 participants (Actual) | Interventional | 2004-06-30 | Completed |
| Prospective Randomized Pilot Study Comparing Bivalirudin Versus Heparin in Neonatal and Pediatric Extracorporeal Membrane Oxygenation [NCT03318393] | Phase 4 | 30 participants (Actual) | Interventional | 2018-03-25 | Completed |
| A Randomized, Controlled, Open Label Study of the Efficacy and Safety of the Low Molecular Weight Heparin (LMWH), LovenoxTM (Enoxaparin) Versus HeparinTM (Unfractionated Heparin) for Prevention of Venous Thromboembolism (VTE) in Gynecologic Oncology Patie [NCT01356329] | Phase 3 | 150 participants (Anticipated) | Interventional | 2009-10-31 | Suspended(stopped due to Difficulty in enrolling patients) |
| Assessing Safety and Efficacy of Lean Body Weight-based Intravenous Heparin Dosing in Obese/Morbidly Obese Patients. A Pilot Study [NCT01363193] | | 100 participants (Anticipated) | Interventional | 2011-07-31 | Recruiting |
| Efficacy and Safety of Warfarin Anticoagulation for Prevention of Portal Vein Thrombosis in Liver Cirrhotic Patients With Hypersplenism After Laparoscopic Splenectomy [NCT02238444] | Phase 4 | 60 participants (Anticipated) | Interventional | 2014-09-01 | Recruiting |
| Heparin AnticoaguLation to Improve Outcomes in Septic Shock: The HALO International Phase II RCT [NCT03378466] | Phase 2 | 178 participants (Actual) | Interventional | 2018-03-12 | Terminated(stopped due to infeasible to continue due-to inability to recruit during the COVID-19 pandemic and grants coming to an end.) |
| A Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Dociparstat Sodium in Combination With Standard Chemotherapy for the Treatment of Newly Diagnosed Acute Myeloid Leukemia [NCT04571645] | Phase 3 | 9 participants (Actual) | Interventional | 2021-04-30 | Active, not recruiting |
| Long-term Treatment for Cancer Patients With Deep Venous Thrombosis or Pulmonary Embolism [NCT01164046] | Phase 3 | 56 participants (Actual) | Interventional | 2010-08-31 | Terminated(stopped due to Due to slow inclusion of patients) |
| Low Dose Catheter Directed Thrombolysis for Acute Intermediary-high Risk Pulmonary Embolism [NCT03854266] | Phase 2 | 60 participants (Anticipated) | Interventional | 2020-03-10 | Recruiting |
| Safety and Efficacy of Bivalirudin Versus Heparin for Systemic Anticoagulation in Extracorporeal Membrane Oxygenation: an Open Label, Parallel Group Randomized Pilot Study (BIV-ECMO2) [NCT03965208] | Phase 4 | 34 participants (Anticipated) | Interventional | 2019-05-23 | Recruiting |
| An Open-label, Randomized, Single Center, Crossover Study in Healthy Participants to Assess Lipoprotein Lipase Activity and Levels, and Triglyceride Levels After Heparin Exposure, in Both Fasted and Postprandial State [NCT05178550] | Early Phase 1 | 12 participants (Actual) | Interventional | 2021-12-17 | Completed |
| A Phase IIIb-IV, Randomised, Open Label Trial on Efficacy and Safety of 2 Parallel Groups: Full Dose Tenecteplase Combined With Unfractionated Heparin or Enoxaparin in Acute Myocardial Infarction in the Prehospital Setting (ASSENT 3 Plus) ASSENT 3 Plus Wa [NCT02181998] | Phase 3 | 1,606 participants (Actual) | Interventional | 2000-07-31 | Completed |
| B-Lymphocyte Immunotherapy in Islet Transplantation: Single Subject Modification to Calcineurin-Inhibitor Based Immunosuppression for Initial Islet Graft (CIT-0501) [NCT01049633] | | 0 participants | Expanded Access | | No longer available |
| Treatment Approach in Patients Diagnosed With Pulmonary Thromboembolism With Intermediate-High Risk Interms of Early Mortality After the Establisment of Ege Pulmonary Embolism Team [NCT05512702] | | 100 participants (Anticipated) | Observational | 2022-06-03 | Recruiting |
| A Pilot Study on the Influence of an Optimized Heparin Regimen on the Hemostatic Environment Downstream From the Surgical Clamp in Major Vascular Surgery. [NCT02477072] | | 32 participants (Actual) | Interventional | 2015-09-30 | Completed |
| Multi-center，Single Blind，Prospective Randomized Controlled Trial of Exploration of Anticoagulation Program in Cerebral Aneurysm and Arteriovenous Malformations With Hybrid Operation [NCT03306836] | | 408 participants (Anticipated) | Interventional | 2016-09-30 | Recruiting |
| Intermediate-dose Versus Standard Prophylactic Anticoagulation In cRitically-ill pATIents With COVID-19: An opeN Label Randomized Controlled Trial---A Randomized Trial of Atorvastatin vs. Placebo In Critically-ill Patients With COVID-19 [NCT04486508] | Phase 3 | 600 participants (Actual) | Interventional | 2020-07-30 | Completed |
| Sildenafil Versus Low Molecular Weight Heparin in Fetal Growth Restriction Treatment [NCT03230162] | Phase 3 | 100 participants (Anticipated) | Interventional | 2017-06-01 | Recruiting |
| A Phase I, Single Center, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate Tolerability of C1 Inhibitor (CINRYZE) as a Donor Pre-treatment Strategy in Brain Dead Donors Who Meet a Kidney Donor Risk Index (KDRI) Above 60% [NCT02435732] | Phase 1 | 72 participants (Anticipated) | Interventional | 2020-12-31 | Not yet recruiting |
| [NCT02423642] | | 30 participants (Actual) | Interventional | 2013-07-31 | Completed |
| A Study to Assess Safety and Tolerability of Single Oral Doses of BMS-986177 in Patients With ESRD Treated With Chronic Hemodialysis [NCT03000673] | Phase 1/Phase 2 | 32 participants (Actual) | Interventional | 2017-05-23 | Completed |
| Acute Mesenteric Venous Thrombosis.. in Assiut University Hospital Management Controversies [NCT03483207] | | 30 participants (Anticipated) | Interventional | 2018-04-01 | Not yet recruiting |
| Optimal Cardiopulmonary Bypass and Anticoagulation Management Strategies in Obese Patients Undergoing Cardiac Surgery [NCT03302195] | | 410 participants (Anticipated) | Interventional | 2015-08-21 | Recruiting |
| Optimal Target of Activated Clotting Time During Percutaneous Coronary Intervention and Outcomes: The Randomized OPTIMAL-ACT Trial [NCT03772613] | Phase 2 | 180 participants (Actual) | Interventional | 2019-02-08 | Completed |
| Phase I Study With Pharmacodynamic Determination of Unfractionated Heparin of Porcine Origin of the Company União Química of Subcutaneous Use in Healthy Participants [NCT03113084] | Phase 1 | 38 participants (Anticipated) | Interventional | 2022-08-20 | Suspended(stopped due to Delay in the R&D stage) |
| The Effect of Heparinization Due to LBW in Cardiac Surgery [NCT03113708] | Phase 4 | 50 participants (Anticipated) | Interventional | 2017-04-30 | Not yet recruiting |
| Reduced Anticoagulation Targets in ECLS (RATE) [NCT04536272] | Phase 3 | 330 participants (Anticipated) | Interventional | 2020-10-01 | Recruiting |
| Phase I Study With Pharmacodynamic Determination of Unfractionated Heparin of Porcine Origin of the Company União Química of Intravenous Use in Healthy Participants [NCT03125187] | Phase 1 | 24 participants (Anticipated) | Interventional | 2021-02-20 | Suspended(stopped due to Delay in the R&D stage) |
| Comparisons of Two Low-density Lipoprotein Apheresis Systems in Patients With Homozygous Familial Hypercholesterolemia [NCT02286596] | | 9 participants (Actual) | Observational | 2013-04-30 | Completed |
| A Randomised, Placebo-controlled Trial to Investigate the Efficacy of Intranasal Heparin Treatment to Reduce Transmission of SARS-CoV-2 Infection and COVID 19 Disease Among Household Contacts of SARS-CoV-2+ Adults and Children [NCT05204550] | Phase 2/Phase 3 | 1,100 participants (Anticipated) | Interventional | 2023-01-30 | Recruiting |
| Pregnancy Outcomes in Women With Unexplained Recurrent Pregnancy Loss Treated With Low Dose Aspirin and Unfractionated Heparin [NCT02144064] | Phase 3 | 200 participants (Anticipated) | Interventional | 2019-06-23 | Recruiting |
| A Study Assessing the REG1 Anticoagulation System Compared Heparin in Subjects With Acute Coronary Syndrome [NCT00932100] | Phase 2 | 640 participants (Actual) | Interventional | 2009-07-31 | Completed |
| Taurolidine Citrate and Unfractionated Heparin Combination Versus Unfractionated Heparin Alone in Prevention of Inflammation in Hemodialysis Catheters. [NCT03539718] | Phase 4 | 60 participants (Anticipated) | Interventional | 2018-05-15 | Recruiting |
| The Independent Effect of Level of Kidney Function and Body Composition On Establishing HDL Cholesterol Levels [NCT02755818] | | 50 participants (Actual) | Observational | 2008-10-22 | Terminated(stopped due to insufficient patients with CKD willing to be injected with heparin) |
| Hamburg Edoxaban for Anticoagulation in COVID-19 Study [NCT04542408] | Phase 3 | 140 participants (Actual) | Interventional | 2020-11-12 | Completed |
| Evaluate the Efficacy and Safety of Various Treatment Schemes for Severe Fever With Thrombocytopenia Syndrome：a Prospective, Multicenter, Non-randomized Controlled Intervention Study [NCT05604859] | Phase 4 | 350 participants (Anticipated) | Interventional | 2022-08-19 | Recruiting |
| Efficacy of Nebulized Heparin and Salbutamol in Mechanically Ventilated Patients With Acute Exacerbation Chronic Obstructive Pulmonary Disease: a Randomized Clinical Trial [NCT03333395] | Phase 4 | 60 participants (Actual) | Interventional | 2017-02-01 | Completed |
| Role of Nebulized Heparin in Non-severe and Severe Covid-19 Patients Admitted to COVID Complex LRH, MTI: A Randomized Controlled Trial [NCT05255848] | Phase 2/Phase 3 | 180 participants (Anticipated) | Interventional | 2022-06-20 | Not yet recruiting |
| BivaLirudin versUS Heparin in ECMO - A Registry-embedded, Randomised, Open Label, Feasibility Trial Comparing Two Anticoagulation Strategies in Patients on Extracorporeal Membrane Oxygenation (ECMO) [NCT05959252] | Phase 2 | 80 participants (Anticipated) | Interventional | 2024-01-01 | Not yet recruiting |
| Evaluation of the Efficacy of Anisodamine Hydrobromide Combined With Heparin in the Treatment of Patients With Critical Infection [NCT05634057] | | 782 participants (Anticipated) | Interventional | 2023-12-31 | Not yet recruiting |
| A Pilot Study to Evaluate the Safety and Preliminary Evidence of an Effect of ODSH (2 O, 3-O Desulfated Heparin) in Accelerating Platelet Recovery in Patients Receiving Induction or Consolidation Therapy for Acute Myeloid Leukemia [NCT02056782] | Phase 1 | 12 participants (Actual) | Interventional | 2013-12-31 | Completed |
| D-dimer to Improve Anticoagulation Management in Adult Patients Supported With Extracorporeal Membrane Oxygenation: a Prospective Cohort Study [NCT03261284] | | 300 participants (Anticipated) | Interventional | 2019-03-01 | Active, not recruiting |
| Dynamics of Hemostatic Parameters in COVID-19 and Comparison of Intervention Strategies Through Adaptive Clinical Trial [NCT04466670] | Phase 2 | 379 participants (Anticipated) | Interventional | 2020-07-11 | Recruiting |
| Feasibility to Stop Perdialytic Heparin Therapy in Hemodialysed Patients With HeprAN ™ Membrane and Treated by Long-term Anticoagulation With VKA [NCT04462614] | | 49 participants (Anticipated) | Interventional | 2020-08-31 | Not yet recruiting |
| STUDIO CLINICO RANDOMIZZATO SULL'UTILIZZO DI EPARINA PER LA PROFILASSI DELLA TROMBOFLEBITE DA CATETERE VENOSO PERIFERICO [NCT01131754] | Phase 3 | 214 participants (Actual) | Interventional | 2007-06-30 | Completed |
| Comparative Effectiveness of Heparin Versus Normal Saline in Maintaining Patency of Peripherally Inserted Central Catheter Lines in Oncology Inpatients [NCT05029596] | Early Phase 1 | 142 participants (Actual) | Interventional | 2020-02-12 | Completed |
| Comparison of Analgesia With Fentanyl and Morphine on Platelet Inhibition After Pre-hospital Ticagrelor Administration in Patients With ST-segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention [NCT02531165] | | 38 participants (Actual) | Interventional | 2015-09-30 | Completed |
| Citrasate® Effect On Heparin N Requirements During Hemodialysis Treatment: A Phase IV,Study to Investigate the Effects of Citrasate on Heparin N Requirements During Hemodialysis Treatment in Subjects Maintained on Thrice Weekly Hemodialysis [NCT01092455] | | 300 participants (Anticipated) | Observational | 2009-12-31 | Completed |
| Randomized, Double-blind, Triple-dummy Trial to Compare the Efficacy of Otamixaban With Unfractionated Heparin + Eptifibatide, in Patients With Unstable Angina/Non ST Segment Elevation Myocardial Infarction Scheduled to Undergo an Early Invasive Strategy [NCT01076764] | Phase 3 | 13,220 participants (Actual) | Interventional | 2010-04-30 | Completed |
| Pathogenesis, Diagnosis, Management and Outcome of Hemostatic Complications in Hematopoietic Stem Cell Transplantation: A Prospective Study [NCT02281240] | | 200 participants (Anticipated) | Observational | 2014-12-31 | Recruiting |
| Heparin-bonded Endoluminal Versus Surgical Femoropopliteal Bypass; a Multicentre Randomized Controlled Trial [NCT01220245] | | 129 participants (Actual) | Interventional | 2010-10-31 | Completed |
| Randomized, Open-label, Single-dose, Crossover Study to Evaluate the Pharmacodynamics of an Unfractionated Heparin Compared to Heparin Sodium Injection, USP (Comparator) After Subcutaneous Administration in Healthy Subjects [NCT05788913] | Phase 1 | 68 participants (Anticipated) | Interventional | 2023-06-01 | Not yet recruiting |
| Randomized, Open-label, Single-dose, Crossover Study to Evaluate the Pharmacodynamics of an Unfractionated Heparin Compared to Heparin Sodium Injection, USP (Comparator) After Intravenous Administration in Healthy Subjects [NCT05788900] | Phase 1 | 68 participants (Anticipated) | Interventional | 2023-06-01 | Not yet recruiting |
| "Comparative Study of Two Haemodialyzers VIE 2.1 Versus EVODIAL2.2 in a Strategy of Heparin-free Haemodialysis (HFH)" [NCT01221337] | | 32 participants (Actual) | Interventional | 2010-10-31 | Completed |
| Safety of Heparin Anticoagulation for Prevention of Death in Patients With Septic Shock. [NCT01234285] | Phase 2 | 0 participants (Actual) | Interventional | 2010-12-31 | Withdrawn(stopped due to Sara Cheng, MD has left the Univ. of Colorado and the study has been closed.) |
| Umbilical Cord-derived Mesenchymal Stem Cells for COVID-19 Patients With Acute Respiratory Distress Syndrome (ARDS) [NCT04355728] | Phase 1/Phase 2 | 24 participants (Actual) | Interventional | 2020-04-25 | Completed |
| Clinical Trial Program of a Medical Instrument Product [NCT01157455] | Phase 4 | 1,900 participants (Anticipated) | Interventional | 2010-05-31 | Recruiting |
| Bivalirudin vs Heparin in Elderly Patients With Acute ST-segment Elevation Myocardial Infarction Undergoing Emergency Percutaneous Coronary Intervention [NCT03882775] | Phase 4 | 240 participants (Anticipated) | Interventional | 2019-01-16 | Recruiting |
| Placement of Covered Stents to Treat Hemodialysis Access Stenoses in the Cephalic Arch and Central Veins [NCT01271881] | | 140 participants (Anticipated) | Interventional | 2010-10-31 | Recruiting |
| Thrombolysis or Anticoagulation for Cerebral Venous Thrombosis (TOACT) [NCT01204333] | Phase 2/Phase 3 | 67 participants (Actual) | Interventional | 2011-09-30 | Terminated |
| A Randomized Study Comparing Bivalirudin vs Heparin in Patients With Extracorporeal Membrane Oxygenator (ECMO) Support [NCT03707418] | Phase 1 | 0 participants (Actual) | Interventional | 2021-04-30 | Withdrawn(stopped due to unable to secure funding) |
| Randomized Comparison of Continuous and Intermittent Heparin Infusion During Catheter Ablation of Atrial Fibrillation [NCT01935557] | Phase 3 | 296 participants (Actual) | Interventional | 2012-12-31 | Completed |
| A Randomized Study Aimed at Comparing Activated Partial Thromboplastin Time and Anti-Xa Activity and in Patients Requiring Unfractionated Heparin Infusion [NCT03426982] | Phase 4 | 700 participants (Anticipated) | Interventional | 2018-03-01 | Recruiting |
| A Different Approach to Preventing Thrombosis (ADAPT): A Randomized Controlled Trial Comparing Low Molecular Weight Heparin to Acetylsalicylic Acid in Orthopedic Trauma Patients [NCT02774265] | Phase 3 | 329 participants (Actual) | Interventional | 2016-01-31 | Completed |
| Comparison of Two Dosages of Heparin Before Extracorporeal Circulation [NCT03752437] | Phase 4 | 150 participants (Actual) | Interventional | 2019-10-01 | Completed |
| Efficacy and Local Tolerability of Topically Applied Heparin (Heparin 2,400 IU /ml Cutaneous Spray) on the Suitability of Newly Constructed Primary Arteriovenous Fistulas in Patients Planned for Haemodialysis. A Multicentre, Randomized, Double-blind and P [NCT01382888] | Phase 2 | 30 participants (Actual) | Interventional | 2011-07-31 | Terminated(stopped due to The Sponsor decided to terminate the study due to the low patient recruitment.) |
| Phase 4 Study of Fixed-dose and Titration Schemes of Heparin and Protamine in Cardiopulmonary Bypass Cardiac Surgeries : Evaluation of Post-operatory Blood Loss and Transfusion Requirements [NCT01267487] | Phase 4 | 240 participants (Actual) | Interventional | 2009-07-31 | Completed |
| Utilization of Nebulized Heparin for Patients Receiving Mechanical Ventilation for COVID19-associated Acute Respiratory Failure [NCT04842292] | Phase 2 | 2 participants (Actual) | Interventional | 2021-05-20 | Terminated(stopped due to Lack of enrollment) |
| Prevention of Lower Extremity Deep Venous Thrombosis in the Surgical Intensive Care Unit: a Randomized Trial Comparing Subcutaneous Heparin and Subcutaneous Enoxaparin [NCT01325779] | | 0 participants (Actual) | Interventional | 2011-03-31 | Withdrawn(stopped due to poor enrollment) |
| Influence of Acetylsalicylic Acid and Low Molecular Weight Heparins on the Incidence of Renal Hematoma of Shockwave Lithotripsy [NCT02875717] | | 500 participants (Actual) | Observational | 2009-01-31 | Completed |
| Clinical Evaluation of GSK576428 (Fondaparinux Sodium) in the Treatment of Acute Pulmonary Thromboembolism (PE) [NCT00981409] | Phase 3 | 41 participants (Actual) | Interventional | 2007-07-31 | Completed |
| Deep Venous Thrombosis. Long-Term Results After Treatment With Either Low-Molecular -Weight Heparin or Unfractionated Heparin. Examinations of the Venous System. [NCT00628576] | Phase 3 | 99 participants (Actual) | Interventional | 1993-10-31 | Completed |
| Radiation Dose in Humans From Orally Administered Tc99m-Heparin [NCT04069429] | Early Phase 1 | 8 participants (Actual) | Interventional | 2016-07-31 | Completed |
| Acute STEMI Treated With Primary Angioplasty and Intravenous 0.5 mg/kg Lovenox or UFH to Lower Ischemic and Bleeding Events [NCT00718471] | Phase 3 | 910 participants (Actual) | Interventional | 2008-08-31 | Completed |
| Lipoprotein Lipase Enzyme Activity Assay Validation and Clinical Assessment [NCT02656095] | | 12 participants (Actual) | Observational | 2016-03-31 | Completed |
| Empirical Low Molecular Weight Heparin Administration in the Luteal Phase in Patients With Recurrent Implantation Failures: a Randomized Open Labeled Trial [NCT00750451] | | 0 participants | Interventional | 2006-01-31 | Completed |
| Effect of Anticoagulation in Reducing the Incidence of Splenic/Portal Vein Thrombosis Post-Laparoscopic Splenectomy Protocol Number: 5698 [NCT00769873] | Phase 2 | 35 participants (Actual) | Interventional | 2006-10-31 | Terminated(stopped due to Recruitment was slower than anticipated. Insufficient funding to expand to multi-centered trial.) |
| Comparison of Citrate and Heparin Anticoagulation During Hemodialysis With Medium Cut-off Polyarylethersulphone- Polyvinylpirrolidone (Theranova) Membrane [NCT04139525] | | 32 participants (Actual) | Interventional | 2020-09-15 | Active, not recruiting |
| Bivalirudin vs Heparin in Elderly Patients With Acute Coronary Syndrome Undergoing Elective Percutaneous Coronary Intervention [NCT04046029] | Phase 4 | 240 participants (Anticipated) | Interventional | 2019-07-08 | Recruiting |
| Efficacy of Sodium Heparin 5.000 UI/0.25 mL (Blausiegel) Compared With Heparin Sodium 5.000 USP (APP Pharmaceuticals)for Venous Thromboembolism Prophylaxis In Surgical Patients With Medium Risk For The Thromboembolism Development [NCT00912483] | Phase 3 | 0 participants (Actual) | Interventional | 2010-05-31 | Withdrawn |
| Bridge or Continue Coumadin for Device Surgery Randomized Controlled Trial (BRUISE CONTROL) [NCT00800137] | Phase 4 | 984 participants (Actual) | Interventional | 2008-12-31 | Terminated(stopped due to At time of pre-specified 2nd interim analysis) |
| CoV-Hep Study: Randomized and Paired Clinical Trial Comparing Regional Anticoagulation Modalities in Continuous Venous Venous Hemodialysis in Patients With COVID-19 [NCT04487990] | | 118 participants (Actual) | Interventional | 2020-06-29 | Completed |
| An International, Multicentre, Randomised, Open, Controlled, Two-parallel Group, Phase II Pilot Study to Evaluate the Efficacy and Safety of ARIXTRA™ for Anticoagulation of Patients With Atrial Fibrillation Undergoing Electric Cardioversion Following Tran [NCT00911300] | Phase 2 | 349 participants (Actual) | Interventional | 2009-08-31 | Completed |
| Prospective Cohort Study of Bone Mineral Density and Calcium-phosphorus Metabolism in RSA Patients: Low Molecular Weight Heparin Use Versus Control [NCT05878574] | | 344 participants (Anticipated) | Observational | 2022-11-01 | Recruiting |
| A Phase 2, Randomized, Double-Blind, Placebo-Controlled Multi-Center Single Dose Study to Evaluate the Safety and Effectiveness of VNX001 Compared to Placebo, the Individual Components of Lidocaine, and Heparin in Subjects With Interstitial Cystitis/Bladd [NCT05737121] | Phase 2 | 120 participants (Anticipated) | Interventional | 2023-05-22 | Recruiting |
| Metaxa's Thromboprophylaxis Program in Oncological & Surgical Patients [NCT04248348] | | 600 participants (Anticipated) | Observational | 2018-12-01 | Recruiting |
| Intermittent HEMOdialysis Anticoagulation With TINzaparin Versus Unfractionated Heparin: A Pilot Multicentre Randomized Controlled Trial (HEMO-TIN Trial) [NCT01930396] | Phase 4 | 191 participants (Actual) | Interventional | 2013-09-30 | Completed |
| Pretreatment With Unfractionated Heparin for ST Elevation Myocardial Infarction [NCT05247424] | Phase 4 | 600 participants (Anticipated) | Interventional | 2022-03-10 | Recruiting |
| "A Pilot Study to Evaluate the Safety and Preliminary Evidence of an Effect of ODSH (2-O, 3-O Desulfated Heparin) in Accelerating Platelet Recovery in Pediatric Patients With a Recurrent Solid Tumor Receiving ICE Chemotherapy" [NCT02164097] | Phase 1 | 4 participants (Actual) | Interventional | 2015-01-31 | Terminated(stopped due to low accrual) |
| A Randomized, Double-blind, Triple-dummy, Dose-ranging Study, Including an Active Control of Unfractionated Heparin and Eptifibatide, to Evaluate the Clinical Efficacy and Safety of Otamixaban, in Patients With Non-ST Elevation Acute Coronary Syndrome and [NCT00317395] | Phase 2 | 3,241 participants (Actual) | Interventional | 2006-06-30 | Completed |
| Effect of the Use of Anticoagulant Therapy During Hospitalization and Discharge in Patients With COVID-19 Infection [NCT04508439] | | 130 participants (Anticipated) | Interventional | 2020-06-20 | Recruiting |
| Multi-centre, Double-blind, Randomized, Controlled Trial Comparing Intra-operative Regional Heparinization to Placebo for the Prevention of Deep Vein Thrombosis Following Total Knee Arthroplasty [NCT00253851] | Phase 4 | 30 participants (Actual) | Interventional | 2003-07-31 | Completed |
| An Open-Label Randomized Control Trial of Pre-Operative Low Molecular Weight Heparin Versus Tapered Warfarin as Bridging Therapy for Patients With Implantation of Pacemaker or Defibrillator [NCT02094157] | Phase 3 | 173 participants (Actual) | Interventional | 2007-12-31 | Terminated(stopped due to Change of practice made further recruitment impossible) |
| Comparison of Thrombgolytic and Anticoagulation Therapy in Submassive Pulmonary Embolism in Context of Pulmonary Hypertension, Right Heart Failure and Patient Functional Ability [NCT02132689] | Phase 4 | 100 participants (Actual) | Interventional | 2011-03-31 | Completed |
| Effect of Bivalirudin on Aortic Valve Intervention Outcomes 2/3 (BRAVO 2/3) [NCT01651780] | Phase 3 | 803 participants (Actual) | Interventional | 2012-10-31 | Completed |
| Efficacy Assessment of Methylprednisolone and Heparin in Patients With COVID-19 Pneumonia: A Randomized, Controlled, 2x2 Factorial Study [NCT04485429] | Phase 3 | 0 participants (Actual) | Interventional | 2020-07-20 | Withdrawn(stopped due to It was not possible to perform the study due to the availability and logistics of porcine heparin) |
| Apixaban Versus Low-Molecular Weight Heparin For Thromboprophylaxis In Patients With Acute Spinal Cord Injury: A Pilot Study [NCT03200613] | Phase 2 | 8 participants (Actual) | Interventional | 2017-09-01 | Terminated(stopped due to study not feasible due to too slow recruitment) |
| Study of the Efficacy, Safety and Tolerability of Low Molecular Weight Heparin vs. Unfractionated Heparin as Bridging Therapy in Patients With Embolic Stroke Due to Atrial Fibrillation [NCT02159287] | Phase 2 | 80 participants (Anticipated) | Interventional | 2014-01-31 | Recruiting |
| A Prospective Randomised Controlled Trial [NCT02086019] | | 250 participants (Actual) | Interventional | 2014-05-01 | Completed |
| Citrate Versus Heparin in Continuous Renal Replacement Therapy : Effect on Cardiovascular System and Clot Circuit in Critically Ill Patients [NCT04865510] | | 41 participants (Actual) | Interventional | 2019-02-04 | Completed |
| COVID-19 Disease and Coagulopathy: Assessment of Clotting Factor Levels in Patients With SARS-CoV-2 Infection [NCT04787510] | | 50 participants (Actual) | Observational [Patient Registry] | 2020-12-23 | Completed |
| An Investigation of Clinical Outcomes and Inflammatory Response to Heparin Free Extracorporeal Membrane Oxygenation Support During Clinical Lung Transplantation - a Prospective Double-blind Randomised Feasibility Study [NCT05697692] | Phase 4 | 80 participants (Anticipated) | Interventional | 2022-12-20 | Recruiting |
| Regional Citrate Anticoagulation for Continuous Renal Replacement Therapy During Veno-venous ECMO: a Crossover Randomized Controlled Study [NCT05148026] | | 20 participants (Anticipated) | Interventional | 2021-11-14 | Recruiting |
| A Phase IIIb, Randomised, Open Label Trial With 3 Parallel Groups: Full Dose TNK-tPA Together With Heparin Sodium, Full Dose TNK-tPA Together With Enoxaparin, and Half Dose TNK-tPA Together With Abciximab and Heparin Sodium in Patients With Acute Myocardi [NCT02181985] | Phase 3 | 5,989 participants (Actual) | Interventional | 2000-05-31 | Completed |
| A Randomized, Phase II Study of CX-01 Combined With Standard Induction Therapy for Newly Diagnosed Acute Myeloid Leukemia [NCT02873338] | Phase 2 | 75 participants (Actual) | Interventional | 2016-08-31 | Completed |
| Randomized Double Blind Trial Comparing Heparin and Placebo as Additives to Continuous Infusion in Intensive Care Neonates for Prevention of Ventilation [NCT00196469] | Phase 4 | 270 participants (Anticipated) | Interventional | 2003-12-31 | Recruiting |
| A Single Center Diagnostic, Cross-sectional Study of Coronary Microvascular Dysfunction [NCT03537586] | | 135 participants (Anticipated) | Interventional | 2018-06-29 | Recruiting |
| Randomized Clinical Trial of Sodium Heparin Effectiveness and Security in Patients Submitted to Heart Surgery Using Bypass [NCT00894998] | Phase 3 | 104 participants (Actual) | Interventional | 2009-06-30 | Completed |
| High (100IU/Kg) Versus Standard (50IU/Kg) Heparin Dose for Prevention of Forearm Artery Occlusion Forearm Artery Occlusion [NCT02570243] | Phase 4 | 1,800 participants (Actual) | Interventional | 2015-02-28 | Completed |
| Randomized Clinical Trial of Sodium Heparin Effectiveness and Security in Patients Submitted to Heart Surgery Using Bypass [NCT00905216] | Phase 3 | 104 participants (Anticipated) | Interventional | 2009-06-30 | Recruiting |
| A Phase 2, Open-Label, Parallel Cohort Study of Subcutaneous Amivantamab in Multiple Regimens in Patients With Advanced or Metastatic Solid Tumors Including EGFR-mutated Non-Small Cell Lung Cancer [NCT05498428] | Phase 2 | 390 participants (Anticipated) | Interventional | 2022-11-11 | Recruiting |
| The Clinical Features and Pregnancy Outcomes of Patients With Connective Tissue Disease :a Prospective Cohort Study [NCT04918524] | | 126 participants (Anticipated) | Observational | 2018-09-11 | Recruiting |
| Heparin-binding Protein and Heparins [NCT04146493] | | 60 participants (Actual) | Observational | 2019-04-01 | Completed |
| Phase 3 Study of the Efficacy and Safety of Unfractionated Heparin in Patients With Severe Sepsis/Septic Shock With Suspected DIC [NCT02654561] | Phase 3 | 600 participants (Anticipated) | Interventional | 2018-04-12 | Recruiting |
| Dual Arm Factorial Randomized Trial in Patients w/ST Segment Elevation AMI to Compare the Results of Using Anticoagulation With Either Unfractionated Heparin + Routine GP IIb/IIIa Inhibition or Bivalirudin + Bail-out GP IIb/IIIa Inhibition; and Primary An [NCT00433966] | Phase 3 | 3,602 participants (Actual) | Interventional | 2005-03-31 | Completed |
| EArly Discharge After Transradial Stenting of CoronarY Arteries in High-Risk Patients of Bleeding: Bivalirudin to Reduce Bleeding EASY-B2B Study [NCT01084993] | Phase 4 | 2,000 participants (Anticipated) | Interventional | 2010-03-31 | Recruiting |
| Randomized Trial of Prasugrel Plus Bivalirudin vs. Clopidogrel Plus Heparin in Patients With Acute STEMI [NCT00976092] | Phase 4 | 548 participants (Actual) | Interventional | 2009-09-30 | Active, not recruiting |
| Comparison of HYDROLINK™ and HeprAN™ mEmbranes in a Per Dialytic Heparin Weaning Strategy in Chronic Hemodialysis Patients [NCT05117450] | | 302 participants (Anticipated) | Interventional | 2021-11-17 | Recruiting |
| Study on Safety and Efficacy of Bivalirudin During Short-term Intervention of Non-infarction Related Artery for Acute ST-segment Elevation Myocardial Infarction After Emergency Percutaneous Coronary Intervention [NCT04475835] | | 100 participants (Anticipated) | Interventional | 2021-01-12 | Recruiting |
| ONE WEEK VERSUS FOUR WEEK HEPARIN PROPHYLAXIS IN PATIENTS WITH COLORECTAL CANCER UNDERGOING LAPAROSCOPIC SURGERY: INCIDENCE OF VENOUS THROMBOEMBOLISM AND BLEEDING COMPLICATIONS. THE PRO-LAPS STUDY. [NCT01589146] | Phase 3 | 400 participants (Anticipated) | Interventional | 2010-09-30 | Recruiting |
| Open Randomized Multi-Center Study to Evaluate Safety and Efficacy of Low Molecular Weight Sulfated Dextran (LMW-SD) in Islet Transplantation After Kidney Transplantation (CIT-01B) [NCT00790439] | Phase 2 | 0 participants (Actual) | Interventional | 2008-07-31 | Withdrawn(stopped due to Due to funding limitations) |
| Low-Molecular-Weight Heparin for DVT Prophylaxis After Open Reduction and Internal Fixation of Ankle Fractures: A Randomized, Prospective Trial [NCT01029821] | | 100 participants (Anticipated) | Interventional | 2010-02-28 | Recruiting |
| Randomized Clinical Trial of Sodium Heparin Effectiveness and Security in Patients Submitted to Heart Surgery Using Bypass [NCT00894673] | Phase 3 | 104 participants (Actual) | Interventional | 2009-07-31 | Completed |
| Randomized Clinical Trial of Sodium Heparin Effectiveness and Security in Patients Submitted to Heart Surgery Using Bypass [NCT00894829] | Phase 3 | 104 participants (Actual) | Interventional | 2009-06-30 | Completed |
| Randomized Clinical Trial of Sodium Heparin Effectiveness and Security in Patients Submitted to Heart Surgery Using Bypass [NCT00894985] | Phase 3 | 104 participants (Actual) | Interventional | 2009-06-30 | Completed |
| Combined Sonographic Examination and Placenta Protein 13 (PP13) to Compare the Risk for Development of Preeclampsia Among Among Pregnant Women With and Without a History of Preterm Delivery and Those Treated by Progesterone or Clexane [NCT00928213] | Phase 2/Phase 3 | 1,000 participants (Anticipated) | Interventional | 2009-08-31 | Not yet recruiting |
| The Efficacy and Safety of Prophylactic Anticoagulation for Catheter-related Thrombosis in Patients With Cancer and Implantable Venous Access Ports: a Prospective Multi-center Randomized Controlled Trial. [NCT04256525] | Phase 4 | 1,640 participants (Anticipated) | Interventional | 2020-05-01 | Recruiting |
| Acute Effect of Intensive Insulin Infusion on Intestinal Triglyceride-rich-lipoprotein-apoB48 Metabolism in Type 2 Diabetic Patients [NCT00950209] | | 20 participants (Actual) | Interventional | 2008-04-30 | Completed |
| Comparison of the Efficacy and Safety for Different Regimen of Venous Thromboembolism Pharmacoprophylaxis Among Severely Burn Patients [NCT05237726] | | 20 participants (Actual) | Interventional | 2020-04-05 | Completed |
| The Efficacy of Prophylactic Use of Extract of Allium Cepae, Allantoin and Heparin in Patients With Proven Scar Development After Excision of Previous Scar [NCT02708628] | | 120 participants (Actual) | Interventional | 2015-12-31 | Completed |
| Regional Citrate Versus Systemic Heparin Anticoagulation for Continuous Renal Replacement Therapy in Critically Ill Patients With Acute Kidney Injury [NCT02669589] | Phase 4 | 638 participants (Actual) | Interventional | 2016-03-31 | Completed |
| Efficacy and Safety of Short-term Postoperative Anticoagulant Therapy to Prevente Thrombosis in Arterovenous Fistula [NCT04164693] | | 110 participants (Anticipated) | Interventional | 2019-01-01 | Recruiting |
| Evaluation of Extended Infusion Set Wear Using the Medtronic Extended Wear Sof-set Infusion Set [NCT02687256] | Phase 1 | 24 participants (Actual) | Interventional | 2016-03-31 | Completed |
| Randomized Controlled Trial Investigating the Efficacy and Safety of Nebulized Heparin Versus Placebo in Burn Patients With Inhalation Trauma (Hepburn) [NCT01773083] | Phase 3 | 13 participants (Actual) | Interventional | 2013-10-31 | Terminated(stopped due to insufficient recruitment of patients and high costs associated with the purchase and blinding of study medication) |
| A Multicenter, Randomized-Controlled Trial to Evaluate the Efficacy and Safety of Antithrombotic Therapy for Prevention of Arterial and Venous Thrombotic Complications in Critically-Ill COVID-19 Patients [NCT04409834] | Phase 4 | 390 participants (Actual) | Interventional | 2020-08-05 | Completed |
| High Dose Versus Low Dose Heparinization in Patients Undergoing Offpump Coronary Artery Bypass [NCT02812355] | Phase 4 | 900 participants (Anticipated) | Interventional | 2017-01-31 | Recruiting |
| Bivalirudin in Stable Ischemic Heart Disease Patients Undergoing PCI [NCT02787317] | Phase 4 | 1,770 participants (Anticipated) | Interventional | 2016-05-31 | Not yet recruiting |
| Open Study to Evaluate Safety and Efficacy of Allogenic Islet Transplantation Using Islets Coated With Immobilised Heparin [NCT00678990] | | 10 participants (Anticipated) | Interventional | 2019-01-31 | Not yet recruiting |
| The STrategic Reperfusion Early After Myocardial Infarction (STREAM) Anticoagulation With Enoxaparin vs. Unfractionated Heparin in Primary PCI Sub-study. [NCT00882635] | Phase 3 | 44 participants (Actual) | Interventional | 2008-10-31 | Completed |
| The Effect of Exercise on Pharmacodynamics and Pharmacokinetics of a Single Dose of Unfractionated Heparin: A Randomized, Controlled, Cross-over Study [NCT06174961] | Phase 4 | 15 participants (Anticipated) | Interventional | 2023-09-22 | Recruiting |
| Effect of Heparinization on Intracranial Aneurysm [NCT05749393] | | 90 participants (Anticipated) | Interventional | 2023-04-30 | Recruiting |
| The Female Microbiome in Patients Undergoing Bladder Instillation Therapy [NCT05414305] | Phase 2 | 29 participants (Actual) | Interventional | 2020-10-01 | Active, not recruiting |
| Randomized Clinical Trial of Sodium Heparin Effectiveness and Security in Patients Submitted to Heart Surgery Using Bypass [NCT00894959] | Phase 3 | 104 participants (Actual) | Interventional | 2009-07-31 | Completed |
| Efficacy and Safety Study to Evaluate the Use of Nebulized Heparin in Patients With Severe Acute Respiratory Syndrome Covid-19 (SARS-CoV-2) [NCT04530578] | Phase 4 | 200 participants (Anticipated) | Interventional | 2020-06-01 | Recruiting |
| Post Marketing Study of the GORE VIABAHN Endoprosthesis With Heparin Bioactive Surface in the Treatment of Superficial Femoral Artery Obstructive Disease (VIPER) [NCT00541307] | | 119 participants (Actual) | Interventional | 2007-10-31 | Completed |
| Heparin Binding Protein (HBP) in Sepsis for the Prediction of Disease Progression [NCT02533011] | | 1,055 participants (Actual) | Observational | 2015-07-31 | Completed |
| A Phase I/II Study of the Tolerability of Lenalidomide and Low Dose Dexamethasone in Previously Treated Multiple Myeloma Patients With Impaired Renal Function [NCT00790842] | Phase 1/Phase 2 | 63 participants (Actual) | Interventional | 2009-01-21 | Terminated(stopped due to Slow enrollment) |
| Effects of Exercise in Combination With Epoetin Alfa During High-Dose Chemotherapy and Autologous Peripheral Blood Stem Cell Transplantation for Multiple Myeloma [NCT00577096] | | 120 participants (Actual) | Interventional | 2001-10-31 | Completed |
| The Efficiency and Safety of Bivalirudin in latE percuTaneous Coronary inTervention for Patients With ST-Elevation Myocardial InfaRction (BETTER Trial) [NCT04185077] | Phase 4 | 1,200 participants (Anticipated) | Interventional | 2019-11-30 | Not yet recruiting |
| The Safety and Pharmacodynamics of Two Doses of Dabigatran Etexilate in Patients Undergoing Cardiac Catheterization [NCT00818753] | Phase 2 | 53 participants (Actual) | Interventional | 2009-01-31 | Completed |
| Evaluation of Anti-Xa Levels in Surgery Patients Receiving Weight-based Heparin [NCT03516656] | Early Phase 1 | 20 participants (Actual) | Interventional | 2018-03-23 | Completed |
| Anticoagulant Treatments Evaluation During Percutaneous Coronary Angioplasty in Stable Patients [NCT00669149] | Phase 4 | 99 participants (Actual) | Interventional | 2008-06-30 | Terminated(stopped due to recruitment difficulties) |
| A Randomized Non-inferiority Clinical Trial of Heparin Produced by Hipolabor Laboratory(PARINEX®) in Comparation With Heparin Produced by APP PHARMACEUTICALS in Patients With Chronic Renal Failure. [NCT00914472] | Phase 3 | 120 participants (Anticipated) | Interventional | 2010-04-30 | Active, not recruiting |
| Prospective Randomized Phase IV Open Label Comparative Study Of Dalteparin vs Unfractionated Heparin In High Risk Patients Of Non-ST Elevation Acute Coronary Syndromes Intended For Early Invasive Strategy [NCT00435487] | Phase 4 | 173 participants (Actual) | Interventional | 2007-06-30 | Terminated(stopped due to See termination reason in detailed description.) |
| Phase 2a, Multi-Center, Open Label, Randomized, Feasibility/Safety Study Comparing REG1 Anticoagulation System With Unfractionated Heparin in Subjects Undergoing Elective PCI After Pretreatment With Clopidogrel and Aspirin [NCT00715455] | Phase 2 | 26 participants (Actual) | Interventional | 2007-10-31 | Completed |
| A Prospective, Multicenter Trial to Evaluate the Safety and Performance of Spectranetics Laser With Adjunct PTA and GORE VIABAHN Endoprosthesis for the Treatment of SFA Instent Restenosis. [NCT00712257] | | 27 participants (Actual) | Interventional | 2007-11-30 | Terminated(stopped due to Due to safety concerns) |
| FondaparinUx Trial With Unfractionated Heparin (UFH) During Revascularization in Acute Coronary Syndromes (ACS) (FUTURA). A Prospective Study Evaluating the Safety of Two Regimens of Adjunctive Intravenous UFH During PCI in High Risk Patients With Unstabl [NCT00790907] | Phase 4 | 3,235 participants (Actual) | Interventional | 2009-02-28 | Completed |
| A Randomised Study of Taurolock for the Locking of Tunneled Central Venous Catheters in Children With Malignant Diseases. [NCT00735813] | Phase 3 | 129 participants (Actual) | Interventional | 2008-04-30 | Completed |
| Comparative Effectiveness of 30% Trisodium Citrate and Heparin Lock Solutions in Preventing Infection and Dysfunction of Hemodialysis Catheters: a Randomized Controlled Trial (CITRIM Trial) [NCT02563041] | Phase 4 | 179 participants (Actual) | Interventional | 2012-07-31 | Completed |
| [NCT00749619] | Phase 3 | 0 participants | Interventional | 2007-05-31 | Completed |
| Effect of Free Fatty Acids on Androgen Precursors in Vivo in Healthy Young Women [NCT00473603] | | 13 participants (Actual) | Interventional | 2006-12-31 | Completed |
| Heparin Management for Cardiopulmonary Bypass in Cardiac Surgery: A Prospective, Comparative and Randomized Study Evaluating a Dosage Based on the Ideal Body Weight in Obese Patients [NCT02675647] | Phase 4 | 60 participants (Anticipated) | Interventional | 2015-12-31 | Recruiting |
| Safety and Effectiveness of 4% Tetrasodium Ethylenediaminetetraacetic Acid Catheter Lock Solution in Preventing Central Venous Catheter Occlusions in Children With Intestinal Failure: A Randomized Controlled Trial [NCT05879835] | | 124 participants (Anticipated) | Interventional | 2023-09-30 | Not yet recruiting |
| Evaluation of Systemic Leakage When a Heparin or Citrate Lock is Injected and Biological and Clinical Repercussions: Ancillary Study of the VERROU-REA Randomized Controlled Trial [NCT02860299] | Phase 4 | 76 participants (Actual) | Interventional | 2015-02-28 | Completed |
| Ethanol Lock Therapy for the Prevention of Catheter Related Blood Stream Infections [NCT00948441] | | 16 participants (Actual) | Interventional | 2008-08-31 | Completed |
| A Randomized, Partial-Blind, Placebo and Positive-Controlled Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Multiple Ascending Doses of HSK36273 in Healthy Subjects. [NCT05742126] | Phase 1 | 54 participants (Actual) | Interventional | 2022-04-11 | Completed |
| Anticoagulation Medicine in Surgical Repair for Total Anomalous Pulmonary Venous Connection: a Randomize Multi-centers Study [NCT04241380] | | 150 participants (Anticipated) | Interventional | 2020-02-20 | Recruiting |
| ACTION-1: ACT Guided Heparinization During Open Abdominal Aortic Aneurysm Repair, a Randomised Trial. [NCT04061798] | Phase 4 | 750 participants (Anticipated) | Interventional | 2020-03-02 | Recruiting |
| Comparison of Effectiveness and Safety of Three Lock Solutions for Long-Term Central Venous Catheter for Hemodialysis [NCT02618317] | Phase 4 | 75 participants (Actual) | Interventional | 2013-07-31 | Completed |
| Optical Coherence Tomography Guided Antithrombotic Treatment After Endovascular Thrombectomy of the Posterior Circulation [NCT04121611] | | 25 participants (Anticipated) | Interventional | 2019-10-14 | Recruiting |
| Comparison of Topical Tranexamic Acid and Floseal® on Blood Loss After Total Knee Arthroplasty in Patients With a Thromboembolic Risk [NCT02865174] | Phase 4 | 90 participants (Anticipated) | Interventional | 2016-09-30 | Not yet recruiting |
| Bicarbonate vs Heparin Catheter Lock in Chronic Hemodialysis Patients [NCT04054128] | Phase 4 | 60 participants (Actual) | Interventional | 2019-09-11 | Active, not recruiting |
| A Feasibility Study to Inform the Design of a Randomised Controlled Trial to Identify the Most Clinically and Cost Effective Length of Anticoagulation With Low Molecular Weight Heparin In the Treatment of Cancer Associated Thrombosis [NCT01817257] | Phase 2 | 2 participants (Actual) | Interventional | 2013-12-31 | Terminated(stopped due to Early findings showed trial was not feasible) |
| A Randomized Controlled Trial Comparing Low Molecular Weight Heparin and Aspirin to Aspirin Alone in Women With Unexplained Recurrent Pregnancy Loss [NCT00564174] | | 88 participants (Actual) | Interventional | 2000-03-31 | Terminated(stopped due to interim analysis found no difference in LB rate and lower than expected event rate) |
| Efficacy and Safety of an Ethanol/Sodium Citrate Locking Solution to Prevent Hemodialysis Catheter-Related Infections: A Pilot Study [NCT01394458] | | 40 participants (Actual) | Interventional | 2011-08-31 | Completed |
| Ethanol Lock and Risk of Catheter Related Blood Stream Infection in Patients With Haemodialysis Catheter [NCT05953675] | | 280 participants (Anticipated) | Interventional | 2018-08-01 | Active, not recruiting |
| Heparinization vs Salinization of the Peripheral Venous Catheter: a Randomized Clinical Trial [NCT05209841] | | 3,450 participants (Anticipated) | Interventional | 2022-03-16 | Not yet recruiting |
| Safety and Efficacy of Preoperative Administration of Heparin as Thromboprophylaxis in Major Thoracic Surgery [NCT02940444] | Phase 1/Phase 2 | 2,000 participants (Anticipated) | Interventional | 2016-06-30 | Recruiting |
| Fixed Low-dose Heparin Versus Standard Adjusted-dose Heparin Infusion in Adults Receiving Venovenous Extracorporeal Membrane Oxygenation (ECMO) With a Heparin Bonded Circuit. [NCT02966080] | | 0 participants (Actual) | Interventional | 2016-12-31 | Withdrawn(stopped due to No participants enrolled, study will not be conducted.) |
| Low Doses of Lung Radiation Therapy in Cases of COVID-19 Pneumonia: Prospective Multicentric Study in Radiation Oncology Centers [NCT04394182] | | 15 participants (Anticipated) | Interventional | 2020-04-21 | Suspended(stopped due to lack of recruitment) |
| Efficacy and Safety of Body Weight Adjusted Nadroparin vs Standard Unfractionated Heparin for the Initial Treatment of Pulmonary Thromboembolism：a Multi-Centre, Randomised Controlled Trial in China [NCT00796692] | Phase 4 | 274 participants (Actual) | Interventional | 2002-06-30 | Completed |
| Assessing Effects of Heparin Priming and Pass Number on Tissue Quality of Fine Needle Biopsies [NCT04764396] | | 100 participants (Anticipated) | Interventional | 2021-03-12 | Recruiting |
| NON CLINICAL INFERIORITY OF HEPARIN SODIUM PRODUCED BY HIPOLABOR FARMACEUTICA LTDA COMPARED TO THE HEPARIN SODIUM PRODUCED BY APP PHARMACEUTICALS IN VENOUS THROMBOEMBOLISM PROPHYLAXIS, IN SURGICAL PATIENTS WITH MEDIUM RISK FOR DEVELOPMENT OF THROMBOEMBOLI [NCT00934167] | Phase 2/Phase 3 | 140 participants (Anticipated) | Interventional | 2010-05-31 | Active, not recruiting |
| Efficacy and Safety of Oral Rivaroxaban for the Treatment of Venous Thromboembolism in Patients With Active Cancer. A Pilot Study. [NCT02746185] | Phase 3 | 159 participants (Actual) | Interventional | 2016-09-30 | Completed |
| Efficacy and Safety of Apixaban, Warfarin and Aspirin Anticoagulation for Prevention of Portal Vein Thrombosis in Liver Cirrhotic Patients After Laparoscopic Splenectomy [NCT04645550] | Phase 4 | 120 participants (Actual) | Interventional | 2020-11-22 | Completed |
| Addition of Prednisolone and Heparin in Patients With Repeated Implantation Failures: a Prospective Clinical Study [NCT01590173] | Phase 2/Phase 3 | 86 participants (Actual) | Interventional | 2012-01-31 | Completed |
| A Novel Catheter Lock Solution for Treatment of Tunneled Hemodialysis Catheter-Associated Bacteremia [NCT00614679] | Phase 1 | 18 participants (Actual) | Interventional | 2006-10-31 | Completed |
| Intrauterine Adhesions Prevention: the Use of Heparin Solution Compared to Application of Anti-adhesion Barrier Gel After Operative Hysteroscopy [NCT05257213] | | 100 participants (Anticipated) | Interventional | 2022-02-14 | Recruiting |
| A Randomised Controlled Trial Comparing the Effectiveness of Heparin Bonded or Antibiotic Impregnated Central Venous Catheters (CVCs) With Standard CVCs for the Prevention of Hospital Acquired Blood Stream Infection in Children [NCT01029717] | Phase 3 | 1,859 participants (Actual) | Interventional | 2010-12-31 | Completed |
| Effect of Intravenous Continuous Infusion Heparin on Rates of Venous Thromboembolism in High-Risk, Critically Ill Patients [NCT02707263] | | 0 participants (Actual) | Interventional | 2016-03-31 | Withdrawn |
| A Multinational, Randomized, Double-Blind, Double-Dummy, Exploratory, Parallel Group, Dose-Ranging Phase II Study to Evaluate Pharmacodynamics, Safety and Tolerability, and Pharmacokinetics of Several Intravenous Regimens of Factor Xa Inhibitor Otamixaban [NCT00133731] | Phase 2 | 947 participants (Actual) | Interventional | 2004-09-30 | Completed |
| Prognosis Related to Induced Thrombopenia With Heparin Under Venoarterial ECMO in Reanimation [NCT03979625] | | 39 participants (Actual) | Observational | 2016-01-01 | Completed |
| Partial Thromboplastin Time During the First 24 Hours of Antithrombotic Prophylaxis Using Unfractionated Heparin: Comparison of a 2 Times Per Day Versus Per 3 Times a Day Dosage [NCT01070875] | | 53 participants (Actual) | Interventional | 2010-04-30 | Completed |
| Low Dose Aspirin and Low-molecular-weight Heparin in the Treatment of Pregnant Libyan Women With Recurrent Miscarriage [NCT01917799] | Phase 4 | 150 participants (Anticipated) | Interventional | 2009-01-31 | Recruiting |
| INHALEd Nebulised Unfractionated HEParin for the Treatment of Hospitalised Patients With COVID-19 (INHALE-HEP) Australia [NCT05184101] | Phase 2/Phase 3 | 100 participants (Anticipated) | Interventional | 2023-08-31 | Recruiting |
| Low Dose Unfractioned Heparin for Treatment of Sepsis Caused by Abdominal Infection：a Pilot Study [NCT04861922] | Phase 3 | 100 participants (Anticipated) | Interventional | 2021-05-11 | Recruiting |
| RCT for the Treatment of Hemodialysis Catheter-Related Bacteremia [NCT02040818] | Phase 2/Phase 3 | 0 participants (Actual) | Interventional | 2013-11-30 | Withdrawn(stopped due to no enrollment) |
| Do Different Heparin Brands Influence Bleeding in Coronary Surgery [NCT00848796] | | 100 participants (Actual) | Interventional | 2006-09-30 | Completed |
| [NCT00000472] | Phase 3 | 0 participants | Interventional | 1989-04-30 | Completed |
| Combined Administration of Inhaled DNase, Baricitinib and Tocilizumab as Rescue Treatment in Severe COVID-19 Patients [NCT05279391] | | 150 participants (Anticipated) | Interventional | 2020-10-25 | Recruiting |
| INHALEd Unfractionated HEParin for the Treatment of Hospitalized Patients With COVID-19 Pneumonia [NCT04723563] | Phase 4 | 50 participants (Actual) | Interventional | 2021-02-22 | Completed |
| Heparin Versus Prostacyclin in Continuous Hemodiafiltration for Acute Renal Failure: Effects on Platelet Responsiveness in the Systemic Circulation and Across the Filter. [NCT00890214] | Phase 4 | 23 participants (Actual) | Interventional | 2007-09-30 | Completed |
| PROphylaxis for ThromboEmbolism in Critical Care Trial (PROTECT Pilot) [NCT00182364] | Phase 3 | 120 participants | Interventional | 2003-02-28 | Completed |
| The Potential Role for Adenosine in the Haemodynamic Effects of Free Fatty Acids [NCT00184899] | | 20 participants | Interventional | 2005-08-31 | Completed |
| A Randomized Controlled Pilot Trial of When Heparin Stopped for Anticoagulation During Extracorporeal Membrane Oxygenation Decannulation [NCT05239637] | | 40 participants (Anticipated) | Interventional | 2022-02-15 | Recruiting |
| Prospective Randomized Phase IV Open Label Comparative Study Of Dalteparin vs Unfractionated Heparin For The Prevention Of Venous Thromboembolism (VTE) In Hospitalized Acutely Ill Medical Patients. [NCT00445328] | Phase 4 | 84 participants (Actual) | Interventional | 2007-06-30 | Terminated(stopped due to See Detailed Description) |
| Heparin Resistance During Off-pump Coronary Artery Bypass Graft Surgery: Predictors and Clinical Implication [NCT01044888] | | 199 participants (Actual) | Interventional | 2007-04-30 | Completed |
| Predictive Factors of Intestinal Infraction in Patients With Acute Mesenteric Ischemia [NCT02645240] | Phase 4 | 97 participants (Actual) | Interventional | 2015-10-31 | Completed |
| Recurrent Urinary Tract Infections and Heparin: a Double-blind Randomized Trial (RUTIH Trial) [NCT02246270] | Phase 1/Phase 2 | 30 participants (Anticipated) | Interventional | 2017-11-28 | Recruiting |
| Switching From Arixtra (Fondaparinux) to Angiomax (Bivalirudin) or Unfractionated Heparin in Patients With Acute Coronary Syndromes (ACS) Without ST-segment Elevation Undergoing Percutaneous Coronary Intervention (PCI): SWITCH III [NCT00464087] | Phase 3 | 100 participants (Actual) | Interventional | 2007-06-30 | Completed |
| A Multicentre, Randomized Controlled Study of Blood Clotting After Transcatheter Atrial Septal Defect Closure [NCT01086046] | | 450 participants (Anticipated) | Interventional | 2009-01-31 | Recruiting |
| Multi-centre, Multi-national, Prospective, Randomised, Open-label, Comparison of Bivalirudin to Other Guideline Based Current Therapies (Excluding Bivalirudin) [NCT01087723] | Phase 3 | 2,198 participants (Actual) | Interventional | 2010-03-31 | Completed |
| Unfractioned Heparin for Treatment of Sepsis: A Randomized Clinical Trial (The HETRASE Study) [NCT00100308] | Phase 3 | 319 participants (Actual) | Interventional | 2005-07-31 | Completed |
| [NCT00207779] | Phase 3 | 0 participants | Interventional | 2005-05-31 | Completed |
| Pilot Study of Intensified Chemotherapy and Simultaneous Treatment With Heparin in Out-patients With Pancreatic Cancer. [NCT01945879] | Phase 1/Phase 2 | 19 participants (Actual) | Interventional | 2003-01-31 | Completed |
| A Double Blinded, Randomized, Controlled Investigation of Taurolidine-citrate/Heparin Catheter Lock Solution Versus Heparin in Patients on Home Parenteral Nutrition With Previously Proven High Risk of Catheter Related Blood Stream Infections. [NCT01948245] | Phase 4 | 42 participants (Anticipated) | Interventional | 2013-10-31 | Active, not recruiting |
| Comparison of Two Strategies for Protamine Dosing After Anticoagulation in Cardiovascular Surgery Regarding Postoperative Bleeding: Total Heparin Administered Versus Residual Heparin Determined by a Pharmacokinetic Model [NCT04628884] | Phase 4 | 136 participants (Anticipated) | Interventional | 2020-11-15 | Recruiting |
| [NCT01956955] | Phase 4 | 150 participants (Anticipated) | Interventional | 2011-01-31 | Recruiting |
| Citrate Versus Heparin for the Lock of Non-tunneled Hemodialysis Catheters in Patients Hospitalised in ICU = Multicentre, Controlled, Randomised Superiority Trial [NCT01962116] | Phase 3 | 405 participants (Actual) | Interventional | 2013-06-14 | Completed |
| Phase 4 Study of Argatroban for Preventing Restenosis After Extracranial Vertebral Artery Stenting [NCT01980316] | Phase 4 | 114 participants (Actual) | Interventional | 2010-04-30 | Completed |
| Multi-Center, Prospective, Randomized, Open-Label, Sponsor-Blinded, Active-Control (Heparin) Clinical Investigation to Evaluate the Safety and Effectiveness of B-Lock™ as an Antimicrobial Catheter Lock Solution in Dialysis Patients With a Central Venous C [NCT01989091] | Phase 3 | 270 participants (Actual) | Interventional | 2012-07-31 | Terminated(stopped due to Did not meet predetermined primary endpoint) |
| D-dimer Adjusted Versus Therapeutic Dose Low-molecular-weight Heparin in Patients With COVID-19 Pneumonia [NCT04584580] | Phase 4 | 50 participants (Anticipated) | Interventional | 2020-08-01 | Recruiting |
| Clinical Outcomes About Heparin Surface Modified Aspheric Lens [NCT02026765] | | 20 participants (Actual) | Interventional | 2013-11-30 | Completed |
| Prevention of Tunneled Cuffed Catheter Malfunction With Prophylactic Use of a Taurolidine Locking Solution Containing Urokinase : a Multicentric Randomized Controlled Trial [NCT02036255] | Phase 3 | 68 participants (Actual) | Interventional | 2015-05-31 | Completed |
| A Phase 3, Randomized, Parallel-Group, Multi-Center, Multi-National Study for the Evaluation of Efficacy and Safety of (LMW) Heparin/Edoxaban Versus (LMW) Heparin/Warfarin in Subjects With Symptomatic Deep-Vein Thrombosis (DVT) and or Pulmonary Embolism ( [NCT00986154] | Phase 3 | 8,292 participants (Actual) | Interventional | 2009-10-31 | Completed |
| Optimal Heparin Dosing Regimens for Cardiopulmonary Bypass [NCT00587444] | Phase 3 | 270 participants (Actual) | Interventional | 2001-06-30 | Completed |
| Multizenterstudie Der European Assessment Group for Lysis in the Eye (EAGLE) Zur Behandlung Des Zentralarterienverschlusses (ZAV): Lysetherapie Versus Konservative Therapie [NCT00637468] | Phase 3 | 84 participants (Actual) | Interventional | 2002-09-30 | Terminated(stopped due to Due to results of conditional power analysis performed at the first interim analysis and due to observed spectrum of adverse events.) |
| Effects of UFH and LMWH on Osteoprotegerin and RANKL Plasma Levels in Hemodialysis Patients [NCT00669721] | | 40 participants (Anticipated) | Interventional | 2008-03-31 | Recruiting |
| Anticoagulant Efficacy and Safety of BivalirUdin Versus heparIn During coiL Embolization in Patients With ruptureD Intracranial Aneurysms: an Open-label, Multicenter, Randomized Pilot Study（BUILD） [NCT04532333] | Phase 3 | 236 participants (Anticipated) | Interventional | 2020-08-31 | Not yet recruiting |
| Exposure of Salvaged Blood to Inflammation and Oxidative Stress: the Effect of Different Anticoagulant Regimes. Heparin vs Citrate in Cellsaver (HECICS). [NCT02674906] | | 75 participants (Actual) | Interventional | 2016-02-29 | Completed |
| Monitoring Anticoagulation With Argatroban in Patients on Extracorporeal Membrane Oxygenation for Severe Lung Failure Using Anti-FIIa. Monitoring Anticoagulation With Unfractionated Heparin in Patients on Extracorporeal Membrane Oxygenation for Severe Lun [NCT06038682] | | 100 participants (Actual) | Observational | 2020-04-01 | Completed |
| InterMediate ProphylACtic Versus Therapeutic Dose Anticoagulation in Critically Ill Patients With COVID-19: A Prospective Randomized Study (The IMPACT Trial) [NCT04406389] | Phase 4 | 14 participants (Actual) | Interventional | 2020-10-13 | Terminated(stopped due to Low accrual) |
| MANCO: Measuring the ACT During Non-cardiac Arterial Procedures. [NCT03426293] | | 500 participants (Anticipated) | Observational [Patient Registry] | 2016-12-21 | Recruiting |
| Platelet Function With New Pediatric Oxygenator and Heparin and Non Heparin Coating in Pediatric Cardiac Surgery [NCT01648712] | | 48 participants (Actual) | Interventional | 2013-03-31 | Terminated(stopped due to for difficulty to enroll patients in the study) |
| Prospective Randomized Study Of Anticoagulation Monitoring With Thromboelastography Versus aPTT During Extracorporeal Membrane Oxygenation In Adults [NCT02271126] | Phase 1 | 42 participants (Actual) | Interventional | 2014-09-02 | Completed |
| Efficacy and Safety of Ethanol Lock Therapy for the Prevention of Central Line-associated Bloodstream Infections [NCT02890875] | | 3 participants (Actual) | Interventional | 2016-08-31 | Terminated(stopped due to Low recruitment) |
| Effects of Sequential Compression Devices on Coagulation Parameters Assessed by TEG® in Patients Undergoing Major Abdominal Surgery [NCT00726570] | | 40 participants (Actual) | Interventional | 2008-08-31 | Terminated(stopped due to Failed to reach the expected enrollment rates by the end of 2010) |
| Randomized Control Trial on Citrate as the Central Venous Catheter Lock Solution [NCT00862966] | | 40 participants (Anticipated) | Interventional | 2009-04-30 | Not yet recruiting |
| Comparison of Heparin vs. no Heparin on Duration of Peripherally Inserted Central Catheter Patency in Neonates [NCT00879957] | | 0 participants (Actual) | Interventional | 2010-01-31 | Withdrawn(stopped due to A study was published regarding the same question this study had.) |
| A Randomized Trial of Heparin vs Placebo in Patients Undergoing Cardiac Catheterization Via the Trans-radial Approach [NCT04374799] | Phase 3 | 3,600 participants (Anticipated) | Interventional | 2020-10-05 | Recruiting |
| Open Randomized Mult-Center Study to Evaluate Safety and Efficacy of Low Molecular Weight Sulfated Dextran in Islet Transplantation (CIT-01) [NCT00789308] | Phase 2 | 24 participants (Actual) | Interventional | 2008-07-11 | Completed |
| Randomized, Blind and Comparative Clinical Trial of Efficacy and Security of Unfractioned Heparin Sodium of Bovine Origin in Patients Submitted to Cardiovascular Surgery With Cardiopulmonary Bypass [NCT01072747] | Phase 3 | 104 participants (Anticipated) | Interventional | 2010-04-30 | Recruiting |
| Cloxacillin as Prevention of Double Lumen Infection in Hemodialysis Patients [NCT00885300] | | 100 participants (Actual) | Interventional | 2008-01-31 | Completed |
| Clinical Trial of Pharmacodynamic Effects and Non-Clinical Inferiority of the Drug Heparin Sodium Produced by the Laboratory Cristália When Compared With the Product Liquemine of Roche Laboratory in Patients With Chronic Renal Failure [NCT00828776] | Phase 2/Phase 3 | 62 participants (Actual) | Interventional | 2007-09-30 | Completed |
| Non-randomized, Open-label, Historical Control, Single Group Assignment Trial of a Reduced Dose of Unfractionated Heparin in Patients Undergoing Percutaneous Coronary Interventions [NCT00735280] | Phase 4 | 2,505 participants (Actual) | Interventional | 2008-08-31 | Completed |
| Evaluation of the Efficacy and Safety of Regional Anticoagulation With Citrate in Extended Hemodialysis in Patients With Acute Renal Injury Admitted to an Intensive Care Unit [NCT04297839] | Phase 3 | 200 participants (Anticipated) | Interventional | 2019-02-12 | Suspended(stopped due to DUE TO CORONAVIRUS DISEASE, ACTIVITIES INTHE HOSPITAL ARE SUPRESSED) |
| Evaluation of the Amiens University Hospital Neuroradiology Anticoagulation Protocol [NCT02848612] | | 459 participants (Actual) | Observational | 2015-11-20 | Completed |
| A Prospective Study of Coronary Artery Bypass Graft and/or Aortic Valve Replacement With Conventional Versus Half Heparin Dose Under Closed and Coated Extra Corporeal Circulation System (MECC) - APPACHES Study. [NCT00657475] | Phase 4 | 238 participants (Actual) | Interventional | 2008-06-30 | Completed |
| Relationship Between Activated Clotting Time and Occlusion of Radial Artery When Used as Vascular Access for Percutaneous Endovascular Procedures. [NCT02762344] | | 2,168 participants (Anticipated) | Observational [Patient Registry] | 2016-05-31 | Recruiting |
| Pivotal/Phase III Multicentered, Two-Arm, Randomized Study Comparing the Effects of AAT-023 Solution (Zuragen), and Heparin on the Incidence of Catheter Related Blood Stream Infections in Tunneled Chronic Central Venous Catheters for Dialysis [NCT00628680] | Phase 3 | 415 participants (Actual) | Interventional | 2006-07-31 | Active, not recruiting |
| The Application of Ticagrelor Combined With Low Molecular Weight Heparin During PCI [NCT02658838] | Phase 4 | 300 participants (Anticipated) | Interventional | 2015-04-30 | Active, not recruiting |
| Clinical Evaluation of GSK576428 (Fondaparinux Sodium) in the Treatment of Acute Deep Vein Thrombosis (DVT) [NCT00911157] | Phase 3 | 39 participants (Actual) | Interventional | 2008-06-30 | Completed |
| The Efficacy and Safety of Batroxobin Combined With Anticoagulation in Cerebral Venous Sinus Thrombosis [NCT04269954] | Phase 4 | 60 participants (Anticipated) | Interventional | 2020-03-01 | Not yet recruiting |
| STOPping Anticoagulation for Isolated or Incidental Subsegmental Pulmonary Embolism [NCT04727437] | Phase 3 | 1,466 participants (Anticipated) | Interventional | 2021-04-08 | Recruiting |
| The Effect of a Heparin-coated Dialysis Filter (Evodial) on Clotting and Intravascular Coagulation During Hemodialysis (HD) When Compared to a Conventional Polyflux Filter (170H) [NCT01388270] | Phase 4 | 12 participants (Actual) | Interventional | 2011-09-30 | Completed |
| Treatment of Intrauterine Growth Restriction With Low Molecular Heparin: Randomized Clinical Trial. Tratamiento Del Crecimiento Intrauterino Restringido Precoz Con Heparina de Bajo Peso Molecular: Ensayo clínico Aleatorizado. [NCT03324139] | Phase 3 | 50 participants (Anticipated) | Interventional | 2017-10-31 | Not yet recruiting |
| Phase I/II Evaluation of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Effects of a Single Escalating Dose of PER977 Following Administration of Unfractionated Heparin [NCT02206087] | Phase 1/Phase 2 | 60 participants (Actual) | Interventional | 2014-06-30 | Completed |
| Phase III Study Analyzing the Effectiveness of Dalteparin Therapy as Intervention in Recurrent Pregnancy Loss [NCT00400387] | Phase 3 | 449 participants (Actual) | Interventional | 2006-11-30 | Completed |
| A Randomised, Open, Parallel-group, Multicentre Study to Examine the Safety and Effectiveness of Three Doses of Argatroban as Anticoagulant in Combination With Clopidogrel and Aspirin in Patients Undergoing Elective Percutaneous Coronary Intervention in C [NCT00508924] | Phase 2 | 140 participants (Actual) | Interventional | 2005-08-31 | Completed |
| A Phase 3, Open-label, Randomized, Multi-center, Controlled Trial to Evaluate the Pharmacokinetics and Pharmacodynamics of Edoxaban and to Compare the Efficacy and Safety of Edoxaban With Standard of Care Anticoagulant Therapy in Pediatric Subjects From B [NCT02798471] | Phase 3 | 290 participants (Actual) | Interventional | 2017-03-27 | Completed |
| Apixaban for Prevention of Portal Vein Thrombosis in Liver Cirrhotic Patients After Laparoscopic Splenectomy and Azygoportal Disconnection for Portal Hypertension [NCT05304455] | | 40 participants (Actual) | Interventional | 2022-04-01 | Completed |
| Prophylaxis of Thrombosis With Implantable Devices for Central Venous Access in Cancer Patients : Phase III Randomised Study [NCT00199602] | Phase 3 | 420 participants (Actual) | Interventional | 1999-08-31 | Completed |
| Value of Abciximab in Patients With AMI Undergoing PCI After High Dose Clopidogrel Pretreatment (BRAVE 3) [NCT00133250] | Phase 4 | 800 participants (Actual) | Interventional | 2003-06-30 | Completed |
| Partial Thromboplastin Time After 72 Hours of Antithrombotic Prophylaxis Using Unfractionated Heparin: Comparison of a 2 Times Per Day Versus a 3 Times Per Day Dosage. [NCT01855516] | | 83 participants (Actual) | Interventional | 2013-09-30 | Completed |
| Monitoring the Efficacy and Safety of Heparin and Nadroparin in the Acute Phase of Ischemic Stroke [NCT01862978] | Phase 4 | 150 participants (Anticipated) | Interventional | 2013-05-31 | Recruiting |
| The Use of Intravascular Paclitaxel for the Treatment of Upper-Extremity Arteriovenous Access Fistula Stenosis: A Randomized Study [NCT01868984] | Phase 2 | 10 participants (Actual) | Interventional | 2013-05-31 | Terminated(stopped due to catheters no longer available - difficult to recruit subjects) |
| Hamidiye Faculty of Nursing, University of Health Sciences [NCT05469035] | | 80 participants (Anticipated) | Interventional | 2022-07-15 | Not yet recruiting |
| Intranasal Heparin Tolerability Study [NCT04490239] | Early Phase 1 | 6 participants (Actual) | Interventional | 2020-10-09 | Completed |
| Timing of Venous Thromboembolism Prophylaxis in Traumatic Brain Injury [NCT03081169] | Phase 4 | 0 participants (Actual) | Interventional | 2017-04-03 | Withdrawn(stopped due to Recruitment not started due to potential conflicting study at same institution. May renew study in the future.) |
| Efficacy of Low Dose Intravenous Heparin in Preventing Thromboembolism in the SICU. [NCT01608906] | | 152 participants (Actual) | Interventional | 2007-05-31 | Completed |
| Phase II Trial of a Novel Catheter Lock Solution For Adjunctive Treatment of Hemodialysis Catheter-Associated Bacteremia. [NCT01483872] | Phase 3 | 9 participants (Actual) | Interventional | 2012-03-31 | Terminated(stopped due to The study was stopped due to poor enrollment.) |
| Comparison of A-priori Versus Provisional Heparin Therapy on Radial Artery Occlusion After Transradial Coronary Angiography and Patent Hemostasis [NCT01489917] | | 428 participants (Actual) | Interventional | 2009-05-31 | Completed |
| Randomized, Open-label (Double Blind Among Rivaroxaban Groups in the Initial 3 Weeks), Parallel-group, Active-controlled Study of Rivaroxaban in Patients With Acute Symptomatic Deep Vein Thrombosis Without Symptomatic Pulmonary Embolism [NCT01516840] | Phase 3 | 60 participants (Actual) | Interventional | 2012-03-31 | Completed |
| Comparison of Bivalirudin and Unfractioned Heparin in Elective Percutaneous Coronary Interventions [NCT00448461] | Phase 4 | 850 participants (Actual) | Interventional | 2007-03-31 | Completed |
| Residual Vein Thrombosis Establishes the Optimal Duration of Low Molecular Weight Heparins in Cancer Patients With Deep Vein Thrombosis of the Lower Limbs [NCT00450645] | Phase 4 | 300 participants (Anticipated) | Interventional | 2005-03-31 | Recruiting |
| A Clinical Trial to Evaluate the Postoperative Portal Vein Infusion of 5-Fluorouracil and Heparin in Patients With Resectable Adenocarcinoma of the Colon [NCT00427310] | Phase 3 | 1,158 participants (Actual) | Interventional | 1984-03-31 | Completed |
| A Randomised Controlled Trial of Taurolidine With Heparin for Prevention of Recurrence of Catheter Related Bacteraemia in Haemodialysis Patients. [NCT01243710] | Phase 4 | 27 participants (Actual) | Interventional | 2010-08-31 | Completed |
| Improving the Diagnosis of Heparin-Induced Thrombocytopenia: Utility of the 4T's Score and Evaluation of New Rapid Assays [NCT00489437] | Phase 1 | 536 participants (Actual) | Interventional | 2007-12-31 | Completed |
| A Phase 2a, Randomized, Double-Blind, Placebo-Controlled Multi-Center Single Dose Study to Evaluate the Safety and Effectiveness of URG101 Compared With the Individual Components Lidocaine and Heparin in Subjects With Interstitial Cystitis/Bladder Pain Sy [NCT02591199] | Phase 2 | 92 participants (Actual) | Interventional | 2015-09-30 | Terminated(stopped due to Prematurely terminated based on interim study analysis) |
| Anticoagulation in the Management of Grade I-III Blunt Cerebrovascular Injuries [NCT00494156] | | 0 participants (Actual) | Interventional | 2003-07-31 | Withdrawn(stopped due to Study halted prematurely prior to enrollment of first participant.) |
| A Study Comparing Angiomax (Bivalirudin) to Heparin With Protamine Reversal in Patients Undergoing Coronary Artery Bypass (OPCAB) Surgery [NCT00073593] | Phase 3 | 150 participants (Actual) | Interventional | 2003-08-31 | Completed |
| UFH is the Most Used Anticoagulant in Hemodialysis, Decreasing the Risk of Clot Formation in the Circuit. [NCT05148377] | Phase 3 | 128 participants (Actual) | Interventional | 2007-08-01 | Completed |
| Prophylactic Intravitreal 5-Fluorouracil and Heparin to Prevent PVR in High-risk Patients With Retinal Detachment. [NCT02834559] | Phase 3 | 326 participants (Actual) | Interventional | 2016-10-27 | Completed |
| A Randomized 3 Period Crossover Study to Investigate the Effect of Triferic Plus Heparin Infusion Compared to Heparin Alone on Coagulation Parameters in Hemodialysis Patients [NCT04042324] | Phase 1/Phase 2 | 12 participants (Actual) | Interventional | 2019-09-30 | Completed |
| Clinical Study to Assess the Safety of the Use of the Drug Heparin Sodium Produced by the Laboratory Blausiegel Compared in Parallel to the Product Liquemine ® Laboratory Roche in Patients With Chronic Renal Failure. [NCT01229072] | Phase 2/Phase 3 | 60 participants (Anticipated) | Interventional | 2008-07-31 | Suspended |
| A Randomized Trial of Bladder Instillations Versus Onabotulinumtoxin A for Treatment of Interstitial Cystitis/Bladder Pain Syndrome [NCT04401176] | Phase 2 | 58 participants (Actual) | Interventional | 2020-09-15 | Completed |
| Bivalirudin vs Heparin During Primary Percutaneous Coronary Intervention in Acute Myocardial Infarction: A Randomised Controlled Trial [NCT02897037] | Phase 3 | 380 participants (Anticipated) | Interventional | 2016-11-30 | Recruiting |
| A Randomized, Double-blind, Single-dose, 2-Treatment, 2-Period, 2-Sequence Crossover Bioequivalence Study Comparing Two Formulations of Insulin Glulisine (Insulin Glulisine 300 Units/mL Versus Insulin Glulisine 100 Units/mL Marketed as Apidra® 100 Units/m [NCT02910518] | Phase 1 | 44 participants (Actual) | Interventional | 2017-02-17 | Completed |
| Pharmacodynamics Study of Enoxalow, Produced by Blau Farmacêutica S/A, Compared to Clexane, Produced by Sanofi-Aventis Farmacêutica Ltda, in Healthy Subjects After Subcutaneous Administration. [NCT01692158] | Phase 1 | 36 participants (Actual) | Interventional | 2013-03-31 | Completed |
| A Prospective, Randomized, Open-label Study to Evaluate the Effect of LOW-molecular-weight Heparin in Reducing Radial Artery Occlusion Rate After Transradial Coronary Catheterization Procedures [NCT04196309] | Phase 4 | 60 participants (Actual) | Interventional | 2017-05-25 | Completed |
| Multi-center Application of Bivalirudin in High-risk Bleeding Patients With Non-valvular Atrial Fibrillation Undergoing Percutaneous Left Atrial Appendage Occlusion [NCT04195997] | Phase 4 | 100 participants (Anticipated) | Interventional | 2020-02-01 | Not yet recruiting |
| Early Effects of Low Molecular Weight Heparin Therapy With Soft-Mist Inhaler for COVID-19 Induced Hypoxemia: A Phase IIb Trial [NCT04990830] | Phase 2/Phase 3 | 80 participants (Actual) | Interventional | 2021-02-03 | Completed |
| An Open-label Comparison of the Efficacy and Safety of the Low-molecular-weight Heparin (3000 U Anti-Xa Once Daily) With Unfractionated Heparin for the Prevention of Thromboembolic Complications in Acutely Ill Non-surgical Patients [NCT00311753] | Phase 3 | 342 participants (Actual) | Interventional | 2006-02-28 | Completed |
| Efficacy and Safety of Warfarin Anticoagulation for Prevention of Portal Vein Thrombosis in Liver Cirrhotic Patients After Laparoscopic Splenectomy and Azygoportal Disconnection for Portal Hypertension [NCT02247414] | Phase 4 | 124 participants (Actual) | Interventional | 2014-09-30 | Completed |
| Sirolimus-Eluting, Heparin-Coated Cobalt Chromium Balloon-Expandable Stent in the Treatment of Patients With de Novo Coronary Artery Lesions in Small Vessels (EVOLUTION) [NCT00233779] | Phase 2 | 52 participants (Actual) | Interventional | 2003-10-31 | Completed |
| The Incidence of Thromboembolic Events in Patients With Antibodies to Heparin-PF4 After Cardiac Bypass [NCT00237328] | | 1,015 participants (Actual) | Observational | 2006-06-30 | Completed |
| THE PRISM Study-Low-Molecular-Weight Heparin Versus Unfractionated Heparin for Perioperative Bridging Anticoagulation: the Patient Preference for Self-Injection Study and Related Measurements [NCT00253396] | Phase 4 | 100 participants (Anticipated) | Interventional | 2005-10-31 | Completed |
| Prospective, Randomized, Double-Blind, Active-Controlled, Multicenter Trial of Bivalirudin and Un-fractionated Heparin in Patients Undergoing Percutaneous Coronary Interventions. ISAR-REACT-3 [NCT00262054] | Phase 4 | 4,570 participants (Actual) | Interventional | 2005-11-30 | Completed |
| [NCT01651923] | Phase 1 | 60 participants (Anticipated) | Interventional | 2013-02-28 | Not yet recruiting |
| Safety and Efficacy of the Use of Regional Anticoagulation With Citrate in Continuous Venovenous Hemofiltration, a Randomized Controlled Trial Comparing Anticoagulation With Citrate to the Low Molecular Weight Heparin Nadroparin [NCT00286273] | Phase 4 | 215 participants (Actual) | Interventional | 2003-03-31 | Completed |
| Triple-Blind Clinical Trial With Placebo Control to Evaluate the Efficacy of a Heparin of Low Molecular Weight (Bemiparin) for Treating Slow-Responding Ulcers in Diabetic Foot in Primary Care [NCT00399425] | Phase 2/Phase 3 | 84 participants | Interventional | 2001-06-30 | Terminated |
| A Study Comparing Angiomax (Bivalirudin) to Heparin With Protamine Reversal in Patients Undergoing Cardiac Surgery on Cardiopulmonary Bypass (CPB) [NCT00079586] | Phase 3 | 150 participants (Actual) | Interventional | 2004-04-30 | Completed |
| Comparison of Low-dose Heparin Versus Standard Dose Heparin During Coronary Interventions (DEDICA Trial) [NCT01694459] | Phase 4 | 1,000 participants (Anticipated) | Interventional | 2010-01-31 | Recruiting |
| The Effects of Acupuncture on the Natural Pregnancy in Patients With Recurrent Abortion: a Randomized Prospective Trial [NCT05998421] | | 46 participants (Actual) | Interventional | 2022-03-01 | Completed |
| Optimal Prophylactic Method of Venous Thromboembolism for Gastrectomy in Korean Patients [NCT01448746] | Phase 3 | 682 participants (Actual) | Interventional | 2011-10-31 | Active, not recruiting |
| Bivalirudin in Acute Myocardial Infarction vs Glycoprotein IIb/IIIa and Heparin Undergoing Angioplasty (BRIGHT):a Randomised Controlled Trial [NCT01696110] | Phase 4 | 2,194 participants (Actual) | Interventional | 2012-08-31 | Completed |
| Bioequivalence of Alteplase Derived From Two Different Manufacturing Processes Following Intravenous Administration in Healthy Male Volunteers [NCT04419493] | Phase 1 | 30 participants (Actual) | Interventional | 2020-06-23 | Completed |
| Assessment of the Anti-inflammatory Effect of Unfractionated Heparin Administered Either by Intravenous Infusion Versus Subcutaneous Injection in Critically Ill Septic Patients. A Randomized Controlled Trial [NCT04313790] | Phase 2 | 40 participants (Actual) | Interventional | 2020-08-29 | Completed |
| Effect of Elevated Plasma-Free-Fatty-Acids on Renal Hemodynamic Parameters [NCT00431665] | | 9 participants | Interventional | 1999-07-31 | Completed |
| Enoxaparin Versus Unfractionated Heparin in PCI [NCT00439855] | Phase 4 | 2,100 participants | Interventional | 2003-09-30 | Completed |
| Multicentric, Randomized, Controlled, Double-blind Clinical Trial to Assess Perioperative Bridging Therapy With Sodium Bemiparin vs Calcium Unfractionated Heparin in Invasive Procedures, Outpatient Surgery and Laparoscopy Surgery in Patients Receiving Lon [NCT00484822] | Phase 3 | 206 participants (Actual) | Interventional | 2007-02-28 | Terminated(stopped due to The study has been halted prematurely due to a low recruitment.) |
| Low-molecular Heparin Infusion as Anticoagulation for Nocturnal Home Hemodialysis [NCT02957877] | Phase 4 | 12 participants (Anticipated) | Interventional | 2016-03-31 | Recruiting |
| A Randomized Trial of Ultrasound-facilitated, Catheter-directed, Thrombolysis Versus Anticoagulation for Acute Intermediate-high Risk Pulmonary Embolism: The Higher-risk Pulmonary Embolism Thrombolysis Study [NCT04790370] | Phase 4 | 544 participants (Anticipated) | Interventional | 2021-08-02 | Recruiting |
| Can Nebulised HepArin Reduce acuTE Lung Injury in Patients With SARS-CoV-2 Requiring Respiratory Support in Ireland [NCT04511923] | Phase 1/Phase 2 | 40 participants (Anticipated) | Interventional | 2020-12-23 | Recruiting |
| DEFIANCE - ClotTriever® Thrombectomy System vs. Anticoagulation Alone for Treatment of Deep Vein Thrombosis [NCT05701917] | | 300 participants (Anticipated) | Interventional | 2023-01-06 | Recruiting |
| To Determine the Effect of Endogenous GLP-1 Secretion on Islet Function in People With and Without Type 2 Diabetes [NCT04466618] | Phase 3 | 23 participants (Actual) | Interventional | 2021-04-15 | Completed |
| Evaluation of Anti-Xa Levels in Surgery Patients Receiving Fixed Dose Heparin [NCT02970032] | Early Phase 1 | 20 participants (Actual) | Interventional | 2016-11-10 | Completed |
| Concentrated Citrate Locking to Reduce the Incidence of Central Venous Catheter-related Infections and Thrombosis: a Randomized Phase III Study in a Hematological Patient Population [NCT01820962] | Phase 3 | 212 participants (Actual) | Interventional | 2006-07-31 | Terminated(stopped due to Because the inclusion rate was lower than expected.) |
| Preventing COVID-19-associated Thrombosis, Coagulopathy and Mortality With Low- and High-dose Anticoagulation: a Multicentric Randomized, Open-label Clinical Trial [NCT04345848] | Phase 3 | 160 participants (Actual) | Interventional | 2020-04-28 | Terminated(stopped due to Low recruitement) |
| Cohort Multiple Randomized Controlled Trials Open-label of Immune Modulatory Drugs and Other Treatments in COVID-19 Patients CORIMUNO-COAG Trial [NCT04344756] | Phase 2 | 808 participants (Anticipated) | Interventional | 2020-04-20 | Not yet recruiting |
| A Multi-center, Randomized, Open, Positive-controlled Two-stage Phase II Clinical Study to Evaluate the Efficacy, Safety and PK/PD Profiles of Anticoagulation of HSK36273 for Injection in Continuous Renal Replacement Therapy Subjects [NCT05602129] | Phase 2 | 156 participants (Anticipated) | Interventional | 2022-11-30 | Not yet recruiting |
| Differential Effects of Oral and Intravenous Lipid Administration on Leptin Signaling [NCT01520454] | | 26 participants (Actual) | Interventional | 2011-11-30 | Completed |
| Biocompatible Cardiopulmonary Bypass and Neuropsychological Outcome After Coronary Artery Bypass Surgery [NCT00188006] | | 0 participants | Interventional | | Completed |
| Heparin Bonded and Collagen Coated Polyester or Human Umbilical Vein for Femoropopliteal Bypass: a Prospective Randomised Multicentre Trial. [NCT00523263] | Phase 3 | 0 participants | Interventional | 1996-01-31 | Completed |
| A Two Part Study to Assess the Pharmacodynamic Effects of Unfractionated Heparin (UFH) in Healthy Volunteers and the Effects of Bendavia™ and Unfractionated Heparin When Administered Concurrently [NCT01513200] | Phase 1 | 12 participants (Actual) | Interventional | 2012-01-31 | Completed |
| Randomized, Open-label, Parallel-group, Active-controlled Study of Rivaroxaban in Patients With Acute Symptomatic Pulmonary Embolism, With or Without Symptomatic Deep Vein Thrombosis [NCT01516814] | Phase 3 | 40 participants (Actual) | Interventional | 2012-02-29 | Completed |
| Influence by Heparinized Flush Solution of the Radial Artery Catheter: INTEM and HEPTEM Analysis. [NCT01522846] | | 25 participants (Actual) | Observational | 2012-01-31 | Completed |
| An Open-label, Randomized, Parallel-Design Study to Characterize the Effect of Heparin on Palifermin Activity in Healthy Adult Subjects [NCT01163097] | Phase 1 | 44 participants (Actual) | Interventional | 2010-07-31 | Completed |
| Randomized, Controlled Study Comparing EKOS EkoSonic Ultrasound Accelerated Thrombolysis to Anticoagulation in the Treatment of Sub-massive Pulmonary Embolism [NCT01166997] | Phase 3 | 59 participants (Actual) | Interventional | 2010-07-31 | Completed |
| Wet Heparinized Suction: A Novel Technique to Enhance Tissue Acquisition for Endoscopic Ultrasound Guided Fine Needle Biopsy (EUS-FNB) of Solid Abdominal Masses: A Randomized Prospective Trial [NCT05041335] | | 42 participants (Anticipated) | Interventional | 2023-12-15 | Not yet recruiting |
| Study of Standard Maintenance Method of Intravenous Port and Post-operation Pain Analysis [NCT03723187] | | 38 participants (Actual) | Interventional | 2016-08-01 | Completed |
| Low Dose Rt-PA Plus LMWH Compared With LMWH Alone for the Treatment of Normotensive Pulmonary Embolism Patients With Acute RV Dysfunction: A Randomized，Multi-Center，Controlled Trial [NCT01531829] | Phase 4 | 460 participants (Anticipated) | Interventional | 2009-07-31 | Recruiting |
| Double-blinded, Randomized Trial in Severe Pneumonia Patients With Severe Sepsis Investigating the Safety and Efficacy of Co-administration of Iloprost and Ascending Doses of Eptifibatide Compared to Low-molecular-weight Heparin [NCT01532544] | Phase 2 | 5 participants (Actual) | Interventional | 2012-06-30 | Terminated(stopped due to Difficulty recruiting patients, company closed down) |
| Prospective, Randomized Trial Comparing Heparin and Minocycline-EDTA Flush for the Prevention of Catheter-Related Infections and Occlusions [NCT00378781] | | 0 participants (Actual) | Interventional | | Withdrawn(stopped due to Study withdrawn.) |
| Nebulized Enriched Heparin to Treat no Critical Patients With Sars-Cov-2 - Triple Blind Clinical Trial [NCT04743011] | Phase 1/Phase 2 | 50 participants (Anticipated) | Interventional | 2021-06-01 | Recruiting |
| A Randomized Study to Test Peripheral Venous Catheter Lock Therapy With Either Heparin or Saline in Patients Admitted to the Internal Medicine Department [NCT02970409] | | 354 participants (Actual) | Interventional | 2015-10-17 | Completed |
| A Randomized, Double-Blind, Placebo-Controlled Trial of Prophylactic Heparin in Patients With Severe Sepsis and Higher Disease Severity Who Are Undergoing Treatment With Drotrecogin Alfa (Activated) [NCT00049777] | Phase 4 | 2,000 participants | Interventional | 2002-12-31 | Completed |
| The Van Gogh-PE Trial, a Multicenter, International, Randomized, Open-Label, Assessor-Blind, Non-Inferiority Study Comparing the Efficacy and Safety of Once-Weekly Subcutaneous SR34006 With the Combination of (LMW)Heparin and Vitamin K Antagonist (VKA) in [NCT00062803] | Phase 3 | 0 participants | Interventional | 2003-06-30 | Completed |
| [NCT00067093] | Phase 3 | 1,452 participants (Actual) | Interventional | 2003-05-31 | Completed |
| Bivalirudin Plus Stenting in Long Lesion to Avoid Periprocedural Myocardial Necrosis Trial [NCT01555658] | Phase 3 | 204 participants (Anticipated) | Interventional | 2012-04-30 | Not yet recruiting |
| Bivalirudin in Patient at High Risk of Bleeding Undergoing Percutaneous Coronary Interventions. [NCT01465503] | Phase 3 | 837 participants (Actual) | Interventional | 2008-01-31 | Completed |
| Once-daily Oral Direct Factor Xa Inhibitor BAY59-7939 in Patients With Acute Symptomatic Deep-vein Thrombosis The Einstein-DVT Dose-finding Study. A Phase II Evaluation. [NCT00395772] | Phase 2 | 543 participants (Actual) | Interventional | 2004-12-31 | Completed |
| PREVENTion of Clot in Orthopaedic Trauma (PREVENT CLOT): A Randomized Pragmatic Trial Comparing the Complications and Safety of Blood Clot Prevention Medicines Used in Orthopaedic Trauma Patients [NCT02984384] | Phase 3 | 12,211 participants (Actual) | Interventional | 2017-04-24 | Completed |
| STATUS-PCI: Stable Angina Therapy With Angiomax® or Unfractionated Heparin for patientS Undergoing Percutaneous Coronary Intervention [NCT01464671] | Phase 4 | 260 participants (Actual) | Interventional | 2009-07-31 | Terminated(stopped due to DSMB halted the study early due to futility. There were no safety concerns.) |
| To Study the Effect of Low Molecular Weight Heparin on the Adenomyosis Patients'Outcome of in Vitro Fertilization-embryo Transplantation [NCT04741295] | | 70 participants (Anticipated) | Interventional | 2020-02-01 | Active, not recruiting |
| Multicentric, Prospective, Randomized, Comparing Trial Between Bypass of the Femoropoplitea by PTFE and Heparin Bounded PTFE [NCT00147979] | | 596 participants (Actual) | Interventional | 2004-04-30 | Completed |
| Prophylactic Ethanol Lock Therapy (ELT) in Patients on Home Parenteral Nutrition: A Prospective Randomized Control Trial. [NCT02227329] | Phase 1/Phase 2 | 39 participants (Actual) | Interventional | 2014-07-31 | Terminated(stopped due to Publication of guidelines advising against the use of ethanol locks.) |
| "Effects of Tinzaparin Sodium on Cardio-vascular OUtcomes and on Blood Lipids in Diabetic Patients on Chronic HEmodialysis: A Long-term, Prospective Study (The Tinzaparin COULD HELP Study)." [NCT00407641] | Phase 4 | 0 participants (Actual) | Interventional | 2009-03-31 | Withdrawn(stopped due to Financial and administrative matters did not allow collaboration among centers.) |
| PROphylaxis for ThromboEmbolism in Critical Care Trial (PROTECT) [NCT00182143] | Phase 3 | 3,659 participants (Actual) | Interventional | 2006-05-31 | Completed |
| Clinically-Important Venous Thromboembolism Following Lower Extremity Fractures: Epidemiology & Prevention [NCT00187408] | Phase 4 | 700 participants | Interventional | 2002-08-31 | Completed |
| [NCT00188773] | Phase 4 | 15 participants (Anticipated) | Interventional | 2004-01-31 | Completed |
| Randomized-Double Blind Trial to Assess the Incidence and Clinical Relevance of Heparin-Induced Thrombocytopenia (HIT) Antibodies in Trauma Patients Treated With Unfractionated or Low-Molecular Weight Heparin, the HIT-TRAP Trial [NCT00196417] | Phase 4 | 600 participants | Interventional | 2003-01-31 | Active, not recruiting |
| [NCT00060554] | Phase 2 | 300 participants | Interventional | 2003-04-30 | Withdrawn(stopped due to Drug sold to Sanofi-Aventis who sold it to GSK; OBS no longer owns study and does not have data.) |
| Clinical Efficacy of Heparin and Tocilizumab in Patients With Severe COVID-19 Infection: a Randomized Clinical Trial [NCT04600141] | Phase 3 | 308 participants (Actual) | Interventional | 2020-11-10 | Completed |
| Normal Saline Versus Heparinized Solution Flush for Maintaining Patency of Peripheral Venous Catheters in Children [NCT01794767] | Phase 4 | 52 participants (Anticipated) | Interventional | 2013-01-31 | Suspended(stopped due to difficult recruiting) |
| Anticoagulation-free VV ECMO for Acute Respiratory Failure: A Pilot Safety and Feasibility Randomized Clinical Trial [NCT04273607] | Phase 2/Phase 3 | 40 participants (Anticipated) | Interventional | 2022-09-01 | Recruiting |
| Heparin Requirement in Counterpulsation [NCT00445211] | Phase 2 | 46 participants (Actual) | Interventional | 2006-01-31 | Terminated(stopped due to lack of enrollment) |
| A Multicenter, Adaptive, Randomized Controlled Platform Trial of the Safety and Efficacy of Antithrombotic and Additional Strategies in Hospitalized Adults With COVID-19 [NCT04505774] | Phase 4 | 880 participants (Actual) | Interventional | 2020-09-04 | Active, not recruiting |
| Prophylactic Antimicrobial Catheter Lock in Hemodialysis Patients: A Randomized Controlled Clinical Trial [NCT00571259] | Phase 4 | 303 participants (Actual) | Interventional | 2003-09-30 | Completed |
| Ethanol Locks for the Treatment of Central Venous Line Infections [NCT00680459] | Phase 3 | 13 participants (Actual) | Interventional | 2008-05-31 | Terminated(stopped due to inability to enroll adequate number of patients) |
| Nebulized Heparin vs. Placebo for the Treatment of COVID-19 Induced Lung Injury [NCT04397510] | Phase 4 | 50 participants (Anticipated) | Interventional | 2020-06-01 | Enrolling by invitation |
| A Pilot Study of CX-01 Combined With Azacitidine in the Treatment of Relapsed or Refractory Myelodysplastic Syndrome and Acute Myeloid Leukemia [NCT02995655] | Phase 1 | 20 participants (Actual) | Interventional | 2017-04-07 | Completed |
| Rivaroxaban Versus Low-molecular-weight Heparin in Preventing Thrombosis Among Cancer Patients After Femoral Venepuncture [NCT03282643] | Phase 1/Phase 2 | 74 participants (Actual) | Interventional | 2016-02-16 | Completed |
| [NCT00371020] | Phase 3 | 0 participants | Interventional | 2005-02-28 | Active, not recruiting |
| A Trial of Intravesical Therapy for Interstitial Cystitis in Patients With Generalized Vulvodynia [NCT01048177] | Phase 2 | 0 participants (Actual) | Interventional | 2012-12-31 | Withdrawn(stopped due to This trial was never started) |
| Unfractionated Heparin in COVID-19 and Non-COVID-19 Patients - an Observational Study. [NCT05509647] | | 1,500 participants (Actual) | Observational | 2014-01-01 | Completed |
| Increased Risk of Venous Thromboembolism and Higher Hypercoagulable State in Patients Recovered in Intensive Care Unit and in Medical Ward for Coronavirus Disease 2019 (COVID-19) [NCT04359212] | | 90 participants (Actual) | Observational | 2020-05-01 | Completed |
| A Randomized, Open-Label, Parallel-Group, Multi-Center Study for the Evaluation of Efficacy and Safety of Edoxaban Monotherapy Versus (LMW) Heparin/Warfarin in Subjects With Symptomatic Deep-Vein Thrombosis - Edoxaban Thrombus Reduction Imaging Study [NCT01662908] | Phase 2 | 85 participants (Actual) | Interventional | 2012-08-31 | Completed |
| PROSPECTIVE STUDY ON PREOPERATIVE VERSUS POSTOPERATIVE VENOUS THROMBOPROPHYLAXIS IN PATIENTS UNDERGOING MAJOR COLORECTAL SURGERY [NCT01976988] | Phase 3 | 410 participants (Actual) | Interventional | 2013-09-30 | Completed |
| A Phase II Multi-Center, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Safety and Efficacy of Intravesical Alkalinized Lidocaine-Heparin for the Symptoms of Pelvic Pain and/or Urgency of Bladder Origin [NCT00256542] | Phase 2 | 90 participants | Interventional | 2006-01-31 | Completed |
| A Phase III, Randomized, Double-Blind, Placebo-Controlled Trial Evaluating Clinical Outcomes Following Percutaneous Coronary Intervention in Patients Treated With an Abciximab Bolus Plus 12-Hour Infusion Given With Either Standard-Dose Weight-Adjusted Hep [NCT00269880] | Phase 3 | 2,792 participants (Actual) | Interventional | 1995-02-28 | Completed |
| Cervical Artery Dissection in Stroke Study [NCT00238667] | Phase 3 | 250 participants (Actual) | Interventional | 2005-11-30 | Completed |
| Steroids and Unfractionated Heparin in Critically Ill Patients With Pneumonia From COVID-19 Infection. A Multicenter, Interventional, Randomized, Three Arms Study Design [NCT04528888] | Phase 3 | 210 participants (Anticipated) | Interventional | 2020-11-25 | Recruiting |
| Heparin Anticoagulation to Improve Outcomes in Septic Shock: The HALO Pilot [NCT01648036] | Phase 2 | 76 participants (Actual) | Interventional | 2012-07-31 | Completed |
| A Study to Evaluate the Use of SOMVC001 (GALA) Vascular Conduit Preservation Solution in Patients Undergoing Coronary Artery Bypass Grafting (CABG) [NCT02272582] | | 100 participants (Actual) | Interventional | 2014-09-24 | Completed |
| A Multicenter, Randomized Trial Evaluating 30-day and 6-month Clinical Outcomes With Three Different Treatment Strategies (Coronary Angioplasty + Abciximab, Intracoronary Stent + Abciximab, and Intracoronary Stent + Placebo) in Patients Undergoing Percuta [NCT00271401] | Phase 3 | 2,399 participants (Actual) | Interventional | 1996-07-31 | Completed |
| A Randomized, Double-blind, Multi-center Comparison of the Efficacy and Safety of Certoparin (3000 U Anti-Xa o.d.) With Unfractionated Heparin (5000 IU t.i.d.) in the Prophylaxis of Thromboembolic Events in Acutely Ill Medical Patients [NCT00451412] | Phase 3 | 3,254 participants (Actual) | Interventional | 2007-01-31 | Completed |
| Low Dose Anti-inflammatory Radiotherapy for the Treatment of Pneumonia by COVID-19: Multi-central Prospective Study [NCT04380818] | | 106 participants (Anticipated) | Interventional | 2020-06-05 | Recruiting |
| [NCT01626911] | | 60 participants (Anticipated) | Interventional | 2011-09-30 | Recruiting |
| Low Versus High Dose Unfractionated Heparin in Patients Undergoing Angiography Via the Radial Artery [NCT01634438] | Phase 4 | 49 participants (Actual) | Interventional | 2008-07-31 | Completed |
| Comparison of Effectiveness and Complications of Heparin and Sodium Bicarbonate Catheter Lock Solutions in Non-Tunneled Hemodialysis Catheters [NCT04772209] | | 441 participants (Actual) | Interventional | 2021-02-01 | Completed |
| [NCT01652638] | Phase 1 | 44 participants (Anticipated) | Interventional | 2013-02-28 | Not yet recruiting |
| A Randomized Clinical Trial of Using Preconceptional Enoxaparin AND Low Dose Aspirin 81mg in Patient With Antiphospholipid Syndrome(APS) [NCT01661439] | | 316 participants (Anticipated) | Observational | 2012-03-31 | Recruiting |
| Double-Blind, Randomized, Controlled Trial, Small Volume Bolus of Papaverine Versus Heparin to Maintain Patency of Peripheral Arterial Catheters in Pediatric Patients Undergoing Surgical Procedures: Pilot Study [NCT03894904] | Phase 4 | 100 participants (Actual) | Interventional | 2019-04-01 | Completed |
| A Multicenter, Randomized, Controlled, Double-Blind Trial to Investigate the Clinical Efficacy and Tolerability of Early Treatment With Simvastatin 40 mg Daily for 30 Days, Followed by Simvastatin 80 mg Daily Thereafter in Tirofiban-Treated Acute Coronary [NCT00251576] | Phase 3 | 4,497 participants (Actual) | Interventional | 1999-11-01 | Completed |
| Prospective Study on the Treatment of Unsuspected Pulmonary Embolism in Cancer Patients [NCT01727427] | | 695 participants (Actual) | Observational | 2012-11-30 | Completed |
| Catheter-Directed Thrombolysis Versus ANticoagulation Monotherapy in Patients With Acute Intermediate-High Risk PulmonarY Embolism: The CANARY Randomized Clinical Trial [NCT05172115] | Phase 3 | 94 participants (Actual) | Interventional | 2018-12-22 | Terminated(stopped due to Due to the COVID-19 pandemic) |
| Vascular Graft Infections - Epidemiology, Best Treatment Options, Imaging Modalities and Impact of Negative Pressure Wound Therapy [NCT01821664] | | 1,800 participants (Anticipated) | Observational [Patient Registry] | 2013-05-31 | Recruiting |
| Balloon Aortic Valvuloplasty Performed Without Heparin to Decrease Vascular and Bleeding Complications of the Procedure [NCT01823393] | Phase 4 | 94 participants (Actual) | Interventional | 2013-01-24 | Terminated(stopped due to Difficulty of inclusion) |
| Regional Citrate Versus Systemic Heparin Anticoagulation for Super High-flux Continuous Hemodialysis in Septic Shock: Effect on Middle Molecular Weight Molecules Clearances [NCT01839578] | | 30 participants (Anticipated) | Interventional | 2013-05-31 | Recruiting |
| An Open-label, Single Center Study to Evaluate the Efficacy and Safety of Heparin-induced Extracorporeal Lipoprotein Precipitation (H.E.L.P.) Therapy as a Treatment for Non-exudative (Dry) Age-related Macular Degeneration (AMD) [NCT01840683] | | 22 participants (Actual) | Interventional | 2013-05-31 | Completed |
| Bivalirudin Infusion for Ventricular Infarction Limitation [NCT02565147] | Phase 3 | 78 participants (Actual) | Interventional | 2014-12-19 | Terminated(stopped due to Futility at the interim analysis.) |
| Effects of Heparin on Early Patency of Arteriovenous Fistula in Angioaccess Surgery of Patients With End-Stage Renal Disease [NCT02493504] | Phase 4 | 150 participants (Actual) | Interventional | 2011-01-31 | Completed |
| INHALEd Unfractionated HEParin for the Treatment of Hospitalised Patients With COVID-19 Meta-trial [NCT04635241] | Phase 2/Phase 3 | 712 participants (Anticipated) | Interventional | 2020-06-01 | Recruiting |
| A Randomized Phase II Open Label Study to Assess the Efficacy & Safety of Gemcitabine + Abraxane® With or Without ODSH (2-0, 3-0 Desulfated Heparin) as First Line Treatment of Metastatic Pancreatic Cancer [NCT01461915] | Phase 2 | 60 participants (Actual) | Interventional | 2011-11-30 | Terminated |
| Chemoprophylaxis Plus Early Ambulation Prevent Chinese Thoracic Surgery Patients From Pulmonary Embolism [NCT03862755] | Phase 4 | 581 participants (Actual) | Interventional | 2017-08-08 | Completed |
| Pharmacodynamics Study of Enoxalow, Produced by Blau Farmacêutica S/A, Compared to Clexane, Produced by Sanofi-Aventis Farmacêutica Ltda, in Healthy Subjects After Intravenous Administration. [NCT01692171] | Phase 1 | 32 participants (Actual) | Interventional | 2013-02-28 | Completed |
| Observational Studies in Cancer Associated Thrombosis for Rivaroxaban in SwEden (OSCAR-SE) [NCT05150938] | | 5,737 participants (Actual) | Observational | 2022-03-18 | Completed |
| Efficacy and Safety of Vascular Boot Warming Program After Acute DVT±PE for Earlier Resolution of Venous Thromboembolism (VTE) and Prevention of Post Thrombotic Syndrome: A Pilot Study. [NCT03465735] | | 15 participants (Actual) | Interventional | 2017-01-13 | Terminated(stopped due to Due to lack of recruitment of eligible participants) |
| Treatment of Acute Deep Vein Thrombosis of the Lower Extremity With Intraclot, Pulse-Sprayed Recombinant Tissue Plasminogen Activator, Plus Heparin and Warfarin: A Pilot Study [NCT00001713] | Phase 1 | 20 participants | Interventional | 1998-02-28 | Completed |
| Evaluation of the Efficacy of a Surface Modified Intraocular Lens in Reducing Post-Operative Inflammatory Signs Following Extracapsular Surgery in Uveitis Patients With Cataracts [NCT00001311] | Phase 2 | 80 participants | Interventional | 1992-04-30 | Completed |
| Comparative Analysis of Injectable Anticoagulants for Thromboprophylaxis Post Cancer-related Surgery [NCT01444612] | | 4,068 participants (Actual) | Observational | 2010-02-28 | Completed |
| Efficacy of Heparin Nebulization on Lung Injury Score in Inhalation Burn Injury [NCT01454869] | Phase 3 | 0 participants (Actual) | Interventional | 2012-02-29 | Withdrawn(stopped due to Due to insufficient funds) |
| Prospective Study on the Role of Intravenous Unfractionated Heparin Following Digital Replantation and Revascularization [NCT04725201] | Phase 4 | 188 participants (Anticipated) | Interventional | 2021-05-24 | Recruiting |
| Interruptions in the Coagulationsystem in Relation With Cardiac Surgery -A Randomized Study Comparing Two Heparinization Strategies During On-pump Cardiac Surgery [NCT01462968] | | 0 participants (Actual) | Interventional | 2011-11-30 | Withdrawn(stopped due to The study never started due to problems with Laboratory facilities in collaborating center) |
| Antithrombotic Therapy to Ameliorate Complications of COVID-19 (ATTACC), in Collaboration With Accelerating COVID-19 Therapeutic Interventions and Vaccines (ACTIV-4) [NCT04372589] | Phase 2/Phase 3 | 1,200 participants (Actual) | Interventional | 2020-05-20 | Completed |
| Intermediate or Prophylactic-Dose Anticoagulation for Venous or Arterial Thromboembolism in Severe COVID-19: A Cluster Based Randomized Selection Trial (IMPROVE-COVID) [NCT04367831] | Phase 4 | 94 participants (Actual) | Interventional | 2020-05-02 | Completed |
| Effects of Different Concentrations of Pressurized-heparin Flushing Fluid on Coagulation and Platelet Function Monitored by the Sonoclot Analyzer [NCT04355273] | | 60 participants (Actual) | Interventional | 2018-01-24 | Completed |
| A Study to Assess the Effectiveness of Dry Cold Application on Pain Intensity and Bruise at the Subcutaneous Injection Site Among Patients Admitted in Selected Hospital [NCT03233321] | | 60 participants (Actual) | Interventional | 2015-11-30 | Completed |
| Bivalirudin vs Heparin in NSTEMI and STEMI in Patients on Modern Antiplatelet Therapy in SWEDEHEART A Multicenter, Prospective, Randomized Controlled Clinical Trial Based on the SWEDEHEART Platform [NCT02311231] | Phase 4 | 6,012 participants (Actual) | Interventional | 2014-06-30 | Completed |
| A Study on the Impact of Bivalirudin Usage During Percutaneous Coronary Intervention for High-risk Plaques in the Coronary Artery on Post Percutaneous Coronary Intervention Coronary Microcirculation. [NCT05984537] | Phase 4 | 70 participants (Anticipated) | Interventional | 2023-07-01 | Active, not recruiting |
| Hemorrhage Following Small Polyp Resection in the Colon in Anticoagulated Patients: a Prospective Single-blinded Multicenter Study Comparing Warfarin vs. Low Molecular Weight Heparin Based Bridging Anticoagulation [NCT02375646] | | 286 participants (Anticipated) | Interventional | 2015-05-31 | Not yet recruiting |
| Randomized Clinical Trial to Evaluate a Routine Full Anticoagulation Strategy in Patients With Coronavirus (COVID-19) - COALIZAO ACTION Trial [NCT04394377] | Phase 4 | 615 participants (Actual) | Interventional | 2020-06-21 | Completed |
| Heparins for Thromboprophylaxis in COVID-19 Patients: HETHICO Study in Veneto [NCT04393805] | | 744 participants (Actual) | Observational | 2020-06-01 | Completed |
| Observation and Treatment of Pulmonary Microthrombosis in Childhood Pneumonia With Elevated D-dimer [NCT04778917] | Phase 4 | 124 participants (Actual) | Interventional | 2014-12-31 | Completed |
| Venous Thromboembolism in Renally Impaired Patients and Direct Oral Anticoagulants [NCT02664155] | Phase 3 | 203 participants (Actual) | Interventional | 2016-10-19 | Terminated(stopped due to recruiting difficulties) |
| Unfractionated Heparin in Acute Chest Syndrome: A Pilot Feasibility Randomized Controlled Trial of Unfractionated Heparin vs. Standard of Care in Acute Chest Syndrome [NCT02098993] | Phase 2 | 7 participants (Actual) | Interventional | 2014-05-31 | Terminated(stopped due to Poor enrollment.) |
| Study on the Application of a Novel Aspiration Thrombectomy Device Combined With Catheter-directed Thrombolysis for the Treatment of Acute Iliofemoral Deep Venous Thrombosis [NCT02414802] | | 40 participants (Anticipated) | Interventional | 2014-12-31 | Enrolling by invitation |
| Phase 3 Prospective, Multicenter, Double-blind, Randomized, Active Control Study to Demonstrate Safety & Effectiveness of Neutrolin in Preventing Catheter-related Bloodstream Infection in Subjects on Hemodialysis for End Stage Renal Disease [NCT02651428] | Phase 3 | 806 participants (Actual) | Interventional | 2015-12-31 | Completed |
| Safety of Anticoagulant Therapy After Tissue Glue for Gastric Varices [NCT05545475] | | 100 participants (Anticipated) | Observational | 2022-01-01 | Recruiting |
| Determine the Safety/Efficacy of Ticagrelor in Post-transplant Patients With Hepatic Artery Thrombosis (HAT) [NCT04946929] | Phase 3 | 50 participants (Anticipated) | Interventional | 2021-07-31 | Not yet recruiting |
| Compare Effectiveness and Safety Utilizing 4% Sodium Citrate vs. Heparin as a Lock Solution in Central Venous Hemodialysis Catheter Among Hemodialysis Patients [NCT05188339] | Phase 2/Phase 3 | 120 participants (Anticipated) | Interventional | 2022-07-20 | Enrolling by invitation |
| Impact on Anticoagulation Management When Activated Clotting Time is Combined With Heparin Concentration Monitoring in Cardiac Surgery: a Randomised Clinical Trial [NCT05944107] | Phase 4 | 65 participants (Actual) | Interventional | 2021-01-01 | Completed |
| Randomized Comparison of Anticoagulation After Primary Percutaneous Coronary Intervention Using Enoxaparin, ACT Guided Unfractionated Heparin or Bivalirudin Prolongation vs. no Anticoagulation To Improve Clinical Outcome [NCT03664180] | Phase 4 | 2,989 participants (Actual) | Interventional | 2019-01-11 | Completed |
| Concentration and Antibiotic Activity in Antibiotic Lock Solutions [NCT01592032] | Phase 4 | 125 participants (Anticipated) | Interventional | 2012-05-31 | Active, not recruiting |
| "Understanding Heparin Resistance in Cardiac Surgery: Altered Heparin Responsiveness and Its Association With Acute Inflammatory Reactions" [NCT01598883] | Phase 1 | 504 participants (Actual) | Interventional | 2012-06-30 | Completed |
| Effects of Low Dose Aspirin and Low Molecular Weight Heparin Cotreatment, Alone and/or in Combination on Implantation and Clinical Pregnancy Rates in Repeated Implantation Failures in IVF Cycle. [NCT01924104] | Phase 3 | 400 participants (Anticipated) | Interventional | 2013-08-31 | Recruiting |
| The Preventive Effect of Anticoagulants on the Formation of Thrombosis After Splenectomy in Liver Cirrhosis Patients With Portal Hypertension [NCT04397289] | Phase 1/Phase 2 | 70 participants (Actual) | Interventional | 2018-02-12 | Completed |
| Restart Anticoagulation in Patients With Spontaneous Intracerebral Hemorrhage and Mechanical Heart Valves [NCT04450446] | | 100 participants (Anticipated) | Observational | 2015-01-01 | Recruiting |
| Neutrolin Versus Heparin for Locking Hemodialysis Catheters: A Multi-center, Double-Blind, Randomized Controlled Trial [NCT03425448] | | 192 participants (Anticipated) | Interventional | 2019-04-04 | Not yet recruiting |
| Pilot Study of Post-thrombotic Syndrome & Predictors of Recurrence in Cancer Patients With Catheter-related Thrombosis [NCT01999179] | | 27 participants (Actual) | Interventional | 2014-06-30 | Completed |
| Objective Assessment of Pulmonary Embolism Can be Deferred Without Increased Risk [NCT00381511] | Phase 4 | 300 participants | Interventional | 1999-01-31 | Completed |
| [NCT00004694] | | 24 participants | Interventional | 1994-01-31 | Completed |
| [NCT00005684] | | 0 participants | Observational | 1996-03-31 | Completed |
| A Phase Iv Trial To Assess The Effectiveness Of Apixaban Compared With Usual Care Anticoagulation In Subjects With Non-valvular Atrial Fibrillation Undergoing Cardioversion [NCT02100228] | Phase 4 | 1,500 participants (Actual) | Interventional | 2014-07-14 | Completed |
| Racial Differences in Vagal Control of Glucose Homeostasis [NCT02365285] | Phase 1/Phase 2 | 23 participants (Actual) | Interventional | 2015-03-31 | Completed |
| [NCT00000119] | Phase 2 | 0 participants | Interventional | 1994-03-31 | Active, not recruiting |
| Can Nebulised HepArin Reduce morTality and Time to Extubation in Patients With COVID-19 Requiring Mechanical Ventilation Meta-Trial (CHARTER-MT): Protocol for an Investigator-initiated International Meta-trial of Randomised Studies [NCT04545541] | Phase 2/Phase 3 | 300 participants (Anticipated) | Interventional | 2020-11-01 | Recruiting |
| Randomized, Double-Blind, Active-Controlled, Multicenter Trial of Abciximab And Bivalirudin in Patients With Non-ST-Segment Elevation Myocardial Infarction Undergoing Percutaneous Coronary Interventions (ISAR-REACT-4) [NCT00373451] | Phase 4 | 1,721 participants (Actual) | Interventional | 2006-07-31 | Completed |
| Biomarkers for Prediction of and Diagnosis of Ventilator-associated Pneumonia [NCT05117125] | | 1,000 participants (Anticipated) | Observational | 2021-10-15 | Recruiting |
| Release of TFPI by Anticoagulants in Cancer Patients by Standard or LMW Heparin [NCT00004875] | | 6 participants (Actual) | Observational | 1996-07-31 | Completed |
| Comparison of Heparin-based Wet Suction Method With Dry Suction Method in EUS Fine Needle Biopsy of Solid Pancreatic Mass [NCT04707560] | | 50 participants (Anticipated) | Interventional | 2020-01-01 | Recruiting |
| [NCT00370760] | Phase 3 | 0 participants | Interventional | 2006-09-30 | Recruiting |
| A Pilot Study Assessing the Feasibility of a Randomized Controlled Trial Evaluating Aspirin Versus Low-molecular-weight Heparin (LMWH) and Aspirin in Women With Antiphospholipid Syndrome and Pregnancy Loss [NCT03100123] | Early Phase 1 | 1 participants (Actual) | Interventional | 2017-11-06 | Terminated(stopped due to Pilot deemed not feasible by Steering Committee due to recruitment rate.) |
| Ventricular Assist Device Anti-Factor Xa (VAD ANTIX) Monitoring Study: a Prospective Randomized Feasibility Trial [NCT03143569] | | 20 participants (Actual) | Interventional | 2017-05-20 | Completed |
| Active-control, Multicenter, Randomized, Open-label, Safety And Efficacy Study Evaluating The Use Of Apixaban In The Treatment Of Symptomatic Deep Vein Thrombosis And Pulmonary Embolism In Japanese [NCT01780987] | Phase 3 | 80 participants (Actual) | Interventional | 2013-01-31 | Completed |
| The Use of Desirudin Versus Heparin for Thrombosis Prophylaxis in Cardiothoracic Surgery Patients [NCT00329433] | Phase 2/Phase 3 | 120 participants (Actual) | Interventional | 2006-05-31 | Completed |
| Fat Induced Insulin Resistance and Atherosclerosis [NCT02348190] | | 86 participants (Actual) | Interventional | 2003-06-30 | Completed |
| In-Vitro Evaluation of Anticoagulant Therapy Management When Urgent Percutaneous Coronary Intervention is Required in Rivaroxaban-Treated Patients [NCT05541757] | | 30 participants (Actual) | Observational | 2021-01-01 | Completed |
| A Double-Blind, Randomized, Placebo-Controlled, Trial of Ethanol Lock Therapy for Treatment and Secondary Prophylaxis of Central Line Associated Bloodstream Infection (CLABSI) in Children and Adolescents [NCT01472965] | Phase 3 | 95 participants (Actual) | Interventional | 2011-12-29 | Completed |
| Efficacy and Safety of Nafamostat Mesylate for VV-ECMO Anticoagulation: a Randomized, Single-blind, Multicenter Exploratory, Heparin-controlled Trial [NCT05555641] | Phase 2 | 40 participants (Anticipated) | Interventional | 2022-12-20 | Recruiting |
| Comparison of VERapamil vs. Heparin Therapy on Procedural sUccess During Transradial Coronary Procedures (VERMUT Study) [NCT02454491] | Phase 4 | 418 participants (Actual) | Interventional | 2015-05-31 | Completed |
| A Phase 3b, Prospective, Randomized, Open-label, Blind Evaluator (PROBE) Study Evaluating the Efficacy and Safety of (LMW) Heparin/Edoxaban Versus Dalteparin in Venous Thromboembolism Associated With Cancer [NCT02073682] | Phase 3 | 1,046 participants (Actual) | Interventional | 2015-07-16 | Completed |
| A Proposal of a Prospective Study on Prevention of Pregnancy Loss in Women Carrying Inherited Thrombophilia [NCT02385461] | | 108 participants (Anticipated) | Observational [Patient Registry] | 2012-01-31 | Recruiting |
| Post-TIPS Short-term Low Molecular Weight Heparin for the Prevention of Early TIPS Dysfunction [NCT03171727] | | 117 participants (Anticipated) | Interventional | 2017-06-01 | Recruiting |
| Observational Studies in Cancer Associated Thrombosis for Rivaroxaban - United States Cohort [NCT04979780] | | 3,708 participants (Actual) | Observational | 2021-07-20 | Completed |
| Open, Randomized, Active Comparator-controlled, Multi-Center Study to Evaluate Safety and Efficacy of IBsolvMIR® in Islet Transplantation [NCT03867851] | Phase 2 | 18 participants (Anticipated) | Interventional | 2021-02-08 | Recruiting |
| Assessing Safety, Hospitalization and Efficacy of rNAPc2 in COVID-19 (ASPEN-COVID-19) [NCT04655586] | Phase 2/Phase 3 | 160 participants (Actual) | Interventional | 2020-12-10 | Completed |
| The Novel Immunomodulatory and Anticoagulant Therapies for Recurrent Pregnancy Loss [NCT02990403] | Phase 4 | 500 participants (Anticipated) | Interventional | 2014-10-31 | Recruiting |
| Safety Profile of Innohep Versus Subcutaneous Unfractionated Heparin in Elderly Patients With Impaired Renal Function Treated for Acute Deep Vein Thrombosis [NCT00277394] | Phase 4 | 541 participants (Actual) | Interventional | 2005-12-31 | Completed |
| Low-molecular-weight Heparin Versus Unfractionated Heparin in Pregnant Women With History of Recurrent Abortion Secondary to Antiphospholipid Syndrome. A Randomized Controlled Trial [NCT01051778] | Phase 2 | 60 participants (Actual) | Interventional | 2006-06-30 | Completed |
| Evaluating Dose Regimen of Intravenous Unfractionated Heparin and Low Molecular Weight Heparin in Critical Ill Patients Versus Critical Ill COVID-19 Patients Using Anti-Xa Levels. [NCT05224388] | | 813 participants (Actual) | Observational | 2020-01-01 | Completed |
| An Investigator-initiated, Multicentre, Randomized, Trial Comparing Anticoagulation Alone Versus Transjugular Intrahepatic Portosystemic Shunt (TIPS) and Anticoagulation in Patients With Recent Obstructive Portal Vein Thrombosis [NCT03422419] | Phase 3 | 0 participants (Actual) | Interventional | 2018-08-01 | Withdrawn(stopped due to lack of funding) |
| A Blind-adjudication Multi-center Phase II Randomized Clinical Trial of Continuous Low-dose Intravenous Heparin Therapy in Coiled Low-grade Aneurysmal Subarachnoid Hemorrhage Patients With Significant Hemorrhage Burden [NCT02501434] | Phase 2 | 88 participants (Anticipated) | Interventional | 2016-04-30 | Suspended |
| A Randomized, Open-label, Parallel Group Feasibility Study to Determine the Safety and Efficacy of M118 vs. Unfractionated Heparin (UFH) in Subjects With Stable Coronary Artery Disease Undergoing Percutaneous Coronary Intervention (PCI) [NCT00543400] | Phase 2 | 503 participants (Actual) | Interventional | 2007-09-30 | Completed |
| Demonstrated Study on Children Henoch-Schönlein Purpura Nephritis With Multistep Treatment of Traditional Chinese Medicine Combined Disease and Syndrome Differentiation [NCT03591471] | Phase 1/Phase 2 | 500 participants (Anticipated) | Interventional | 2014-09-30 | Recruiting |
| Prismaflex Therapeutic Plasma Exchange: Evaluation of Complication Rates Using Filter vs. Centrifuge and Heparin vs. Citrate Anticoagulation [NCT04351438] | | 108 participants (Actual) | Observational | 2012-01-31 | Active, not recruiting |
| ENDOvascular Interventions With AngioMAX: The ENDOMAX Trial [NCT01913483] | Phase 3 | 732 participants (Actual) | Interventional | 2013-09-24 | Terminated |
| Risk of Hemorrhage in Patients Prescribed Arixtra Compared to LMWH [NCT01064362] | | 13,442 participants (Actual) | Observational | 2010-01-31 | Completed |
| Effectiveness and Safety of Early Administration of Heparin at First Medical Contact for STEMI Patients Undergoing Primary Percutaneous Coronary Intervention: a Multicenter, Prospective, Randomized, Controlled Study [NCT05329155] | | 944 participants (Anticipated) | Interventional | 2022-07-20 | Recruiting |
| Safety and Efficacy of Argatroban Applicated in Anticoagulation of V-V ECMO: A Randomized Controlled Study [NCT04925167] | | 174 participants (Anticipated) | Interventional | 2021-07-06 | Recruiting |
| A Randomised Controlled Trial to Compare Unfractionated Heparin Versus Bivalirudin in the Treatment of Patients With a Clinical Diagnosis of ST-Segment Elevation Myocardial Infarction Events - For Planned Management With Primary PCI [NCT01519518] | Phase 4 | 1,829 participants (Actual) | Interventional | 2012-02-29 | Completed |
| Randomized Study of the Use of Warfarin During Pacemaker or ICD Implantation in Patients Requiring Long Term Anticoagulation [NCT00721136] | | 104 participants (Actual) | Interventional | 2007-09-30 | Completed |
| Heparin and Catheter-related Thrombosis in Neonates and Infants Following Cardiac Surgery [NCT00779558] | | 90 participants (Actual) | Interventional | 2005-11-30 | Completed |
| Anticoagulation Therapies Effect on the Endometrial Blood Flow and Pregnancy Outcomes in Unexplained Recurrent Implantation Failure Women [NCT03365466] | | 200 participants (Anticipated) | Observational | 2017-12-31 | Not yet recruiting |
| Prospective Randomized Trial of Autologous Platelet Rich Plasma in Reducing Allogeneic Transfusions During Aortic Surgery Under Deep Hypothermic Circulatory Arrest [NCT02513862] | | 80 participants (Actual) | Interventional | 2015-05-31 | Completed |
| Comparative Study of Conventional and Topical Heparin Treatments in Second Degree Burn Patients for Burn Analgesia and Duration of Wound Healing [NCT02497326] | | 36 participants (Anticipated) | Interventional | 2015-04-30 | Recruiting |
| The Efficacy of a Lock Solution Containing Taurolidine, Citrate and Heparin for the Prevention of Tunneled Central Line-associated Bloodstream Infections in Pediatric Oncology Patients, a Randomized Controlled, Mono-center Trial. [NCT05740150] | | 462 participants (Anticipated) | Interventional | 2020-10-27 | Recruiting |
| Venous Thromboembolic Prophylaxis After Major Trauma: A Randomized Controlled Trial of Three Times a Day Unfractionated Heparin Versus Twice a Day Enoxaparin [NCT01729559] | Phase 4 | 495 participants (Actual) | Interventional | 2012-11-30 | Completed |
| Clinical Efficacy of Product Alimax ® (Sodic Heparin) in Treatment of Burns: Comparative Study of Raw Materials Between Two Suppliers [NCT00701623] | Phase 2/Phase 3 | 0 participants (Actual) | Interventional | 2008-06-30 | Withdrawn |
| Multicentre, Prospective Randomized Open Label, Blinded-endpoint (PROBE) Controlled Trial of Early Anticoagulation With Rivaroxaban Versus Standard of Care in Determining Safety at 365 Days in Symptomatic Cerebral Venous Thrombosis [NCT03178864] | Phase 2 | 55 participants (Actual) | Interventional | 2019-03-12 | Completed |
| Streptokinase Versus Unfractionated Heparin Nebulization in Patients With Severe Acute Respiratory Distress Syndrome (ARDS): A Partially Randomized Controlled Trial [NCT03465085] | Phase 3 | 60 participants (Actual) | Interventional | 2016-02-18 | Completed |
| Coronary ARteriogenesis With Combined Heparin and EXercise Therapy in Chronic Refractory Angina [NCT03350737] | | 32 participants (Actual) | Interventional | 2013-02-01 | Completed |
| AntiThrombotic Therapy to Ameliorate Clinical Complications in Community Acquired Pneumonia [NCT05848713] | Phase 3 | 4,000 participants (Anticipated) | Interventional | 2023-10-10 | Recruiting |
| Evaluation of GORE VIABAHN Endoprosthesis With Heparin Bioactive Surface for the Treatment of Venous Occlusions and Stenoses [NCT01406795] | | 1 participants (Actual) | Interventional | 2010-12-31 | Terminated(stopped due to Poor enrollment and advances in venoplasty only techniques of the femoral vein) |
| Rate of Venous Thrombosis in Acutely Ill Patients Hospitalized in Internal Medicine Wards [NCT03157843] | | 1,000 participants (Anticipated) | Observational | 2015-02-28 | Recruiting |
| A Randomized, Controlled Trial of Continuous Heparin Versus Placebo Infusion to Prevent Catheter-related Thrombosis in Infants After Cardiac Surgery [NCT04767113] | | 35 participants (Actual) | Interventional | 2021-03-01 | Completed |
| Nebulized Heparin for Prevention of Acute Lung Injury in Adult Patients Suffering Smoke Inhalation Injury: A Randomized Controlled Trial [NCT05886998] | Phase 3 | 100 participants (Anticipated) | Interventional | 2021-11-01 | Recruiting |
| Role of Fatty Acid Oxidation Defects in Insulin Sensitivity [NCT02517307] | | 52 participants (Actual) | Interventional | 2016-02-29 | Completed |
| Heparin Versus Taurolidine to Bloodstream Infection Prevention Related in Central Venous Catheter in Children With Intestinal Failure [NCT02515201] | Phase 4 | 20 participants (Anticipated) | Interventional | 2014-09-30 | Active, not recruiting |
| Comparison of Clinical Pregnancy Rates Between Two Protocols, With or Without Low Molecular Weight Heparin Administration Before Frozen Embryo Transfer in Hormonal Replacement Cycles: a Prospective Randomized Controlled Trial [NCT03120715] | Phase 4 | 342 participants (Anticipated) | Interventional | 2016-07-01 | Recruiting |
| Thromboprophylaxis in Oesophageal Cancer Patients - A Randomized, Controlled Trial [NCT05067153] | Phase 4 | 100 participants (Anticipated) | Interventional | 2021-05-01 | Recruiting |
| Prospective Multi-centre Clinical Study to Assess the Clinical Validity of the Heparin Binding Protein Assay to Indicate the Presence and Outcome of Sepsis in Patients With Suspected Infection Following Emergency Department Admission [NCT03295825] | | 400 participants (Actual) | Interventional | 2017-09-22 | Completed |
| The Effect on Bruising and Pain of Different Durations of Pressure Application Following Subcutaneous Heparin Injection to the Upper Arm [NCT06076434] | | 50 participants (Actual) | Interventional | 2022-11-01 | Completed |
| An Open-label, Randomized, 2-part, Parallel Design Study to Characterize the Effect of Heparin on Palifermin Pharmacokinetics and the Effect of Palifermin on Heparin Pharmacodynamics in Healthy Subjects [NCT00361348] | Phase 1 | 45 participants | Interventional | 2005-12-31 | Completed |
| A Randomized Controlled Comparative Study on Efficacy and Cost-effectiveness of Heparin-bonded Versus Non-heparin-bonded Polytetrafluroethylene Hemodialysis Access Grafts. [NCT01601873] | | 103 participants (Actual) | Interventional | 2012-11-09 | Terminated(stopped due to Results from futility analysis conducted at planned interim time-point did not meet the study criteria for continuation.) |
| Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine [NCT02986594] | Phase 4 | 600 participants (Anticipated) | Interventional | 2016-11-30 | Recruiting |
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] |