Compounds > colneleic acid
Page last updated: 2024-11-11

colneleic acid

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

colneleic acid: structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

colneleic acid : A long-chain, divinyl ether fatty acid composed of 8-nonenoic acid having the E- hydrogen at position 9 substituted by a (1E,3Z)-nona-1,3,-dien-1-yloxy group. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Cross-References

ID SourceID
PubMed CID6441681
CHEBI ID60956
SCHEMBL ID2369985
MeSH IDM0043794

Synonyms (20)

Synonym
9-oxa-8t10t12c-18:3
CHEBI:60956
(8e,1'e,3'z)-9-(1',3'-nonadienyloxy)-8-nonenoic acid
colneleinsaeure
52761-34-9
9-oxa-8t10t12c-c18:3
LMFA10000001
colneleic acid
9-[1'e,3'z-dien-1'-yloxy]-non-8e-enoic acid
(8e)-9-[(1e,3z)-nona-1,3-dien-1-yloxy]non-8-enoic acid
C19827
9-(nona-1',3'-dienoxy)non-8-enoic acid
8-nonenoic acid, 9-(1,3-nonadienyloxy)-, (e,e,z)-
SCHEMBL2369985
(2'e,4'z,8e)-colneleic acid
9-(1,3-nonadienyloxy)-(e,e,z)-8-nonenoic acid
9-[1-l (e),3-l (z)-nonadienyloxy]-8(e)-nonenoic acid
Q27130252
(8e)-9-[(1e,3z)-1,3-nonadien-1-yloxy]-8-nonenoic acid
DTXSID501214758

Research Excerpts

Overview

Colneleic acid is an unsaturated ether fatty acid. It is derived from linoleic acid via a lipoxygenase-mediated enzyme pathway.

ExcerptReferenceRelevance
"Colneleic acid is an unsaturated ether fatty acid derived from linoleic acid via a lipoxygenase-mediated enzyme pathway. "( The enzymic and non-enzymic degradation of colneleic acid, an unsaturated fatty acid ether intermediate in the lipoxygenase pathway of linoleic acid oxidation in potato (Solanum tuberosum) tubers.
Galliard, T; Mathew, JA; Wardale, DA, 1974)		1.96
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (3)

ClassDescription
divinyl ether fatty acidAn oxa fatty acid in which the defining oxa group forms part of a divinyl ether.
long-chain fatty acidA fatty acid with a chain length ranging from C13 to C22.
straight-chain fatty acidAny fatty acid whose skeletal carbon atoms form an unbranched open chain.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (12)

TimeframeStudies, This Drug (%)All Drugs %
pre-19902 (16.67)18.7374
1990's3 (25.00)18.2507
2000's6 (50.00)29.6817
2010's1 (8.33)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other13 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
hydrogen
Hydrogen: The first chemical element in the periodic table with atomic symbol H, and atomic number 1. Protium (atomic weight 1) is by far the most common hydrogen isotope. Hydrogen also exists as the stable isotope DEUTERIUM (atomic weight 2) and the radioactive isotope TRITIUM (atomic weight 3). Hydrogen forms into a diatomic molecule at room temperature and appears as a highly flammable colorless and odorless gas.. dihydrogen : An elemental molecule consisting of two hydrogens joined by a single bond.		2.0210elemental hydrogen;
elemental molecule;
gas molecular entity		antioxidant;
electron donor;
food packaging gas;
fuel;
human metabolite
vinyl ether
vinyl ether: major descriptor (65-85); on-line search VINYL COMPOUNDS (66-85); Index Medicus search VINYL ETHER (65-85)		2.9340ether
linoleic acid
Linoleic Acid: A doubly unsaturated fatty acid, occurring widely in plant glycosides. It is an essential fatty acid in mammalian nutrition and is used in the biosynthesis of prostaglandins and cell membranes. (From Stedman, 26th ed). linoleic acid : An octadecadienoic acid in which the two double bonds are at positions 9 and 12 and have Z (cis) stereochemistry.		2.0810octadecadienoic acid;
omega-6 fatty acid		algal metabolite;
Daphnia galeata metabolite;
plant metabolite
alpha-linolenic acid
linolenic acid : A two-membered subclass of octadecatrienoic acid comprising the (9Z,12Z,15Z)- and (6Z,9Z,12Z)-isomers. Linolenic acids are nutrients essential to the formation of prostaglandins and are also used in making paints and synthetic resins.. linolenate : A polyunsaturated fatty acid anion obtained by deprotonation of the carboxy group of either alpha- or gamma-linolenic acid.		2.4320linolenic acid;
omega-3 fatty acid		micronutrient;
mouse metabolite;
nutraceutical
13-hydroperoxy-9,11-octadecadienoic acid
13-hydroperoxy-9,11-octadecadienoic acid: RN given refers to (E,Z)-isomer; RN for unspecified isomer not in Chemline 8/12/83. 13-HPODE : An HPODE (hydroperoxyoctadecadienoic acid) in which the double bonds are at positions 9 and 11 (E and Z geometry, respectively) and the hydroperoxy group is at position 13.		1.9910hydroperoxy polyunsaturated fatty acid;
octadecadienoic acid
15-hydroperoxy-5,8,11,13-eicosatetraenoic acid
15-hydroperoxy-5,8,11,13-eicosatetraenoic acid: RN given refers to cpd without isomeric designation; (S-(E,Z,Z,Z))-isomer caused dose-dependent constriction of cat coronary arteries; structure in first source. 15-HPETE : A HPETE that consists of (5Z,8Z,11Z,13E)-icosatetraenoic acid in which the hydroperoxy group is located at position 15.		1.9910HPETEhuman xenobiotic metabolite
chlorophyll a
Chlorophyll: Porphyrin derivatives containing magnesium that act to convert light energy in photosynthetic organisms.. chlorophyll : A family of magnesium porphyrins, defined by the presence of a fifth ring beyond the four pyrrole-like rings. The rings can have various side chains which usually include a long phytol chain.		1.9910chlorophyll;
methyl ester		cofactor
etheroleic acid
etheroleic acid: a divinyl ether; structure given in first source. etheroleic acid : A divinyl ether fatty acid that is (9Z,11E,14E)-nonadeca-9,11,14-trienoic acid in which the methylene group at position 10 has been replaced by oxygen.		2.6930divinyl ether fatty acid;
long-chain fatty acid
ConditionIndicatedRelationship StrengthStudiesTrials