| Assay ID | Title | Year | Journal | Article |
|---|
| AID216228 | In vitro binding affinity to vesamicol receptor using [3H]vesamicol. | 1994 | Journal of medicinal chemistry, Aug-05, Volume: 37, Issue:16
| Spirovesamicols: conformationally restricted analogs of 2-(4-phenylpiperidino)cyclohexanol (vesamicol, AH5183) as potential modulators of presynaptic cholinergic function. |
| AID331149 | Displacement of [3H]vesamicol from VAChT receptor in torpedo electrical organ synaptic vesicle | 2008 | Journal of medicinal chemistry, Apr-10, Volume: 51, Issue:7
| First CoMFA characterization of vesamicol analogs as ligands for the vesicular acetylcholine transporter. |
| AID346600 | Displacement of [3H](+)-pentazocine from sigma1 receptor in guinea pig brain membrane by liquid scintillation counting | 2009 | Journal of medicinal chemistry, Mar-12, Volume: 52, Issue:5
| Synthesis and in vitro and in vivo evaluation of 18F-labeled positron emission tomography (PET) ligands for imaging the vesicular acetylcholine transporter. |
| AID346601 | Displacement of [3H]DTG from sigma2 receptor in rat liver membrane | 2009 | Journal of medicinal chemistry, Mar-12, Volume: 52, Issue:5
| Synthesis and in vitro and in vivo evaluation of 18F-labeled positron emission tomography (PET) ligands for imaging the vesicular acetylcholine transporter. |
| AID1233650 | Displacement of (-)-[3H]pentazocine from sigma1 receptor in Sprague-Dawley rat cortical membranes incubated for 2 hrs by liquid scintillation counting based competitive radioligand binding assay | 2015 | European journal of medicinal chemistry, Jul-15, Volume: 100 | New systematically modified vesamicol analogs and their affinity and selectivity for the vesicular acetylcholine transporter - A critical examination of the lead structure. |
| AID346818 | Selectivity ratio of Ki for human vesicular acetylcholine transporter to Ki for sigma2 receptor in rat liver membrane | 2009 | Journal of medicinal chemistry, Mar-12, Volume: 52, Issue:5
| Synthesis and in vitro and in vivo evaluation of 18F-labeled positron emission tomography (PET) ligands for imaging the vesicular acetylcholine transporter. |
| AID671086 | Binding affinity to sigma1 receptor | 2012 | Bioorganic & medicinal chemistry, Jul-15, Volume: 20, Issue:14
| Synthesis and evaluation of in vitro bioactivity for vesicular acetylcholine transporter inhibitors containing two carbonyl groups. |
| AID1233651 | Displacement of [3H]DTG from sigma2 receptor in Sprague-Dawley rat liver membranes incubated for 2 hrs in presence of dextrallorphan by liquid scintillation counting based competitive radioligand binding assay | 2015 | European journal of medicinal chemistry, Jul-15, Volume: 100 | New systematically modified vesamicol analogs and their affinity and selectivity for the vesicular acetylcholine transporter - A critical examination of the lead structure. |
| AID1233652 | Selectivity index, ratio of Ki for sigma1 receptor in Sprague-Dawley rat cortical membranes to Ki for rat VAChT expressed in PC12 cell membranes | 2015 | European journal of medicinal chemistry, Jul-15, Volume: 100 | New systematically modified vesamicol analogs and their affinity and selectivity for the vesicular acetylcholine transporter - A critical examination of the lead structure. |
| AID671085 | Binding affinity to VAChT | 2012 | Bioorganic & medicinal chemistry, Jul-15, Volume: 20, Issue:14
| Synthesis and evaluation of in vitro bioactivity for vesicular acetylcholine transporter inhibitors containing two carbonyl groups. |
| AID216232 | Binding to vesicular acetylcholine transporter of torpedo synaptic vesicles | 1997 | Journal of medicinal chemistry, Nov-21, Volume: 40, Issue:24
| N-hydroxyalkyl derivatives of 3 beta-phenyltropane and 1-methylspiro[1H-indoline-3,4'-piperidine]: vesamicol analogues with affinity for monoamine transporters. |
| AID1233648 | Displacement of (-)-[3H]vesamicol from rat VAChT expressed in PC12 cell membranes incubated for 2 hrs by liquid scintillation counting based competitive radioligand binding assay | 2015 | European journal of medicinal chemistry, Jul-15, Volume: 100 | New systematically modified vesamicol analogs and their affinity and selectivity for the vesicular acetylcholine transporter - A critical examination of the lead structure. |
| AID346817 | Selectivity ratio of Ki for human vesicular acetylcholine transporter to Ki for sigma1 receptor in guinea pig brain membrane | 2009 | Journal of medicinal chemistry, Mar-12, Volume: 52, Issue:5
| Synthesis and in vitro and in vivo evaluation of 18F-labeled positron emission tomography (PET) ligands for imaging the vesicular acetylcholine transporter. |
| AID1233653 | Selectivity index, ratio of Ki for sigma2 receptor in Sprague-Dawley rat liver membranes to Ki for rat VAChT expressed in PC12 cell membranes | 2015 | European journal of medicinal chemistry, Jul-15, Volume: 100 | New systematically modified vesamicol analogs and their affinity and selectivity for the vesicular acetylcholine transporter - A critical examination of the lead structure. |
| AID1233647 | Displacement of (-)-[3H]vesamicol from VAChT in Sprague-Dawley rat brain membranes incubated for 2 hrs by liquid scintillation counting based competitive radioligand binding assay | 2015 | European journal of medicinal chemistry, Jul-15, Volume: 100 | New systematically modified vesamicol analogs and their affinity and selectivity for the vesicular acetylcholine transporter - A critical examination of the lead structure. |
| AID671087 | Binding affinity to sigma2 receptor | 2012 | Bioorganic & medicinal chemistry, Jul-15, Volume: 20, Issue:14
| Synthesis and evaluation of in vitro bioactivity for vesicular acetylcholine transporter inhibitors containing two carbonyl groups. |
| AID1233649 | Displacement of (-)-[3H]vesamicol from VAChT in Torpedo californica electric organ synaptic vesicles | 2015 | European journal of medicinal chemistry, Jul-15, Volume: 100 | New systematically modified vesamicol analogs and their affinity and selectivity for the vesicular acetylcholine transporter - A critical examination of the lead structure. |
| AID476627 | Displacement of [3H]vesamicol from VAChT in Torpedo californica cholinergic synaptic vesicles | 2010 | Journal of medicinal chemistry, Apr-08, Volume: 53, Issue:7
| Synthesis and in vitro biological evaluation of carbonyl group-containing inhibitors of vesicular acetylcholine transporter. |
| AID346599 | Displacement of [3H]vesamicol from human vesicular acetylcholine transporter expressed in rat PC12 cells by liquid scintillation spectrometry | 2009 | Journal of medicinal chemistry, Mar-12, Volume: 52, Issue:5
| Synthesis and in vitro and in vivo evaluation of 18F-labeled positron emission tomography (PET) ligands for imaging the vesicular acetylcholine transporter. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |