Page last updated: 2024-12-08

6-aminophenanthridine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

6-aminophenanthridine: a prion inhibitor; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID160547
CHEMBL ID3290780
SCHEMBL ID72801
MeSH IDM0546562

Synonyms (18)

Synonym
phenanthridine, 6-amino-
brn 0143395
6-aminophenanthridine
2-aminobenzo(c)quinoline
6-phenanthridinamine
832-68-8
phenanthridin-6-amine
CHEMBL3290780
FVCXJXKLDUJOFA-UHFFFAOYSA-N
phenanthridine-6-amine
SCHEMBL72801
DTXSID30232216
6-phenanthridinamine (9ci)
HB3730
AKOS028111334
CS-0109772
HY-135189
PD094382
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (3)

Assay IDTitleYearJournalArticle
AID1155686Antiprion activity against yeast STRg6 prion protein [PSI+] at 50 nmole by colorimetric assay2014European journal of medicinal chemistry, Jul-23, Volume: 82Evaluation of the antiprion activity of 6-aminophenanthridines and related heterocycles.
AID1155687Antiprion activity against yeast SB34 prion protein [URE3] at 50 nmole by colorimetric assay2014European journal of medicinal chemistry, Jul-23, Volume: 82Evaluation of the antiprion activity of 6-aminophenanthridines and related heterocycles.
AID1155688Ex vivo antiprion activity against sheep 127S scrapie prion protein infected in mouse MovS6 cells assessed as PK digestion resistant-PrPSc accumulation after 6 days by immunoblot analysis2014European journal of medicinal chemistry, Jul-23, Volume: 82Evaluation of the antiprion activity of 6-aminophenanthridines and related heterocycles.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (10)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's10 (100.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 18.40

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index18.40 (24.57)
Research Supply Index2.40 (2.92)
Research Growth Index5.62 (4.65)
Search Engine Demand Index10.37 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (18.40)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews2 (20.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (80.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]