Page last updated: 2024-12-08
6-aminophenanthridine
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
6-aminophenanthridine: a prion inhibitor; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 160547 |
| CHEMBL ID | 3290780 |
| SCHEMBL ID | 72801 |
| MeSH ID | M0546562 |
Synonyms (18)
| Synonym |
|---|
| phenanthridine, 6-amino- |
| brn 0143395 |
| 6-aminophenanthridine |
| 2-aminobenzo(c)quinoline |
| 6-phenanthridinamine |
| 832-68-8 |
| phenanthridin-6-amine |
| CHEMBL3290780 |
| FVCXJXKLDUJOFA-UHFFFAOYSA-N |
| phenanthridine-6-amine |
| SCHEMBL72801 |
| DTXSID30232216 |
| 6-phenanthridinamine (9ci) |
| HB3730 |
| AKOS028111334 |
| CS-0109772 |
| HY-135189 |
| PD094382 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (3)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1155686 | Antiprion activity against yeast STRg6 prion protein [PSI+] at 50 nmole by colorimetric assay | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Evaluation of the antiprion activity of 6-aminophenanthridines and related heterocycles. |
| AID1155687 | Antiprion activity against yeast SB34 prion protein [URE3] at 50 nmole by colorimetric assay | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Evaluation of the antiprion activity of 6-aminophenanthridines and related heterocycles. |
| AID1155688 | Ex vivo antiprion activity against sheep 127S scrapie prion protein infected in mouse MovS6 cells assessed as PK digestion resistant-PrPSc accumulation after 6 days by immunoblot analysis | 2014 | European journal of medicinal chemistry, Jul-23, Volume: 82 | Evaluation of the antiprion activity of 6-aminophenanthridines and related heterocycles. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (10)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 10 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 18.40
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (18.40) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 2 (20.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 8 (80.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||