Compounds > 2,2-dimethylthiazolidine
Page last updated: 2024-12-07

2,2-dimethylthiazolidine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

2,2-dimethylthiazolidine: RN given refers to parent cpd; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID88015
SCHEMBL ID248542
MeSH IDM0102627

Synonyms (22)

Synonym
2,2-dimethylthiazolidine
thiazolidine, 2,2-dimethyl-
einecs 242-980-4
brn 0102789
2,2-dimethyl-1,3-thiazolidine
19351-18-9
D1491
A813647
AKOS006230408
2,2-dimethyltetrahydrothiazole
FT-0637834
2,2-dimethyl thiazolidine
dimethylthiazolidine
SCHEMBL248542
DTXSID3051832
W-107715
DS-0840
2,2-dimethyl-1,3-thiazolidine, aldrichcpr
CS-W002096
mfcd00014488
AMY2745
EN300-7116656

Research Excerpts

Bioavailability

ExcerptReferenceRelevance
" However, this strategy suffers from the great conformational flexibility small peptides have in solution, which together with bioavailability represents the most important limitation to the usefulness of synthetic peptides as drugs and as synthetic immunogens."( Stabilization of the biologically active conformation of the principal neutralizing determinant of HIV-1(IIIB) containing a cis-proline surrogate: 1H NMR and molecular modeling study.
Anglister, J; Dumy, P; Garcia, J; Rosen, O, 2006)		0.33
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (10)

TimeframeStudies, This Drug (%)All Drugs %
pre-19906 (60.00)18.7374
1990's0 (0.00)18.2507
2000's2 (20.00)29.6817
2010's0 (0.00)24.3611
2020's2 (20.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 11.74

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index11.74 (24.57)
Research Supply Index2.40 (2.92)
Research Growth Index4.14 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (11.74)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other10 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
iproniazid
[no description available]		1.9510carbohydrazide;
pyridines
thiazoles
[no description available]		3.47801,3-thiazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
thiazolidines
Thiazolidines: Reduced (protonated) form of THIAZOLES. They can be oxidized to THIAZOLIDINEDIONES.		2.3520thiazolidine
proline
Proline: A non-essential amino acid that is synthesized from GLUTAMIC ACID. It is an essential component of COLLAGEN and is important for proper functioning of joints and tendons.. proline : An alpha-amino acid that is pyrrolidine bearing a carboxy substituent at position 2.		7.4320amino acid zwitterion;
glutamine family amino acid;
L-alpha-amino acid;
proline;
proteinogenic amino acid		algal metabolite;
compatible osmolytes;
Escherichia coli metabolite;
micronutrient;
mouse metabolite;
nutraceutical;
Saccharomyces cerevisiae metabolite
2,5-dimercapto-1,3,4-thiadiazole
dimercaptothiadiazole: structure in first source		2.610
cysteine
Cysteine: A thiol-containing non-essential amino acid that is oxidized to form CYSTINE.. L-cysteinium : The L-enantiomer of cysteinium.. cysteine : A sulfur-containing amino acid that is propanoic acid with an amino group at position 2 and a sulfanyl group at position 3.		2.610cysteiniumfundamental metabolite
ConditionIndicatedRelationship StrengthStudiesTrials
Acute Kidney Failure
[description not available]		02.610
Acute Kidney Injury
Abrupt reduction in kidney function. Acute kidney injury encompasses the entire spectrum of the syndrome including acute kidney failure; ACUTE KIDNEY TUBULAR NECROSIS; and other less severe conditions.		02.610
Experimental Neoplasms
[description not available]		01.9610