Compounds > etravirine
Page last updated: 2024-09-05

etravirine and propafenone

etravirine has been researched along with propafenone in 3 studies

Compound Research Comparison

Studies
(etravirine)		Trials
(etravirine)		Recent Studies (post-2010)
(etravirine)		Studies
(propafenone)		Trials
(propafenone)		Recent Studies (post-2010) (propafenone)
572903211,471268239

Protein Interaction Comparison

ProteinTaxonomyetravirine (IC50)propafenone (IC50)
Potassium channel subfamily K member 3Homo sapiens (human)5.1
ATP-binding cassette sub-family C member 9Homo sapiens (human)2.2
5-hydroxytryptamine receptor 4Cavia porcellus (domestic guinea pig)0.384
Potassium channel subfamily K member 2Homo sapiens (human)7.6
Cytochrome P450 1A2Homo sapiens (human)3.292
Beta-2 adrenergic receptorHomo sapiens (human)0.052
Aldo-keto reductase family 1 member B1Rattus norvegicus (Norway rat)3.016
ATP-dependent translocase ABCB1Homo sapiens (human)0.3311
Beta-1 adrenergic receptorHomo sapiens (human)0.354
Cytochrome P450 2D6Homo sapiens (human)4.6034
Beta-3 adrenergic receptorHomo sapiens (human)0.424
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)1.637
Sodium-dependent noradrenaline transporter Homo sapiens (human)3.016
5-hydroxytryptamine receptor 2AHomo sapiens (human)0.654
5-hydroxytryptamine receptor 2CHomo sapiens (human)0.384
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)1.637
5-hydroxytryptamine receptor 2BHomo sapiens (human)0.092
5-hydroxytryptamine receptor 6Homo sapiens (human)1.863
Sodium-dependent dopamine transporter Homo sapiens (human)1.868
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)1.3733
Sodium channel protein type 5 subunit alphaHomo sapiens (human)2.245
ATP-sensitive inward rectifier potassium channel 11Homo sapiens (human)2.2
Sigma non-opioid intracellular receptor 1Homo sapiens (human)2.61

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's2 (66.67)2.80

Authors

AuthorsStudies
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Arnold, E; De Clercq, E; Fang, Z; Feng, D; Kang, D; Liu, X; Pannecouque, C; Pilch, A; Ruiz, FX; Sun, Y; Wang, Z; Wei, F; Zhan, P; Zhao, T1
Daelemans, D; De Clercq, E; Gao, P; Ginex, T; Huang, B; Jiang, X; Kang, D; Liu, X; Luque, FJ; Pannecouque, C; Zhan, P; Zhang, J1

Reviews

1 review(s) available for etravirine and propafenone

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

2 other study(ies) available for etravirine and propafenone

ArticleYear
Discovery and Characterization of Fluorine-Substituted Diarylpyrimidine Derivatives as Novel HIV-1 NNRTIs with Highly Improved Resistance Profiles and Low Activity for the hERG Ion Channel.
    Journal of medicinal chemistry, 2020, 02-13, Volume: 63, Issue:3

    Topics: Animals; Anti-HIV Agents; Cell Line; Crystallography, X-Ray; Drug Discovery; ERG1 Potassium Channel; Female; Fluorine; HIV Reverse Transcriptase; HIV-1; Humans; Male; Mice; Microsomes, Liver; Molecular Structure; Protein Binding; Pyrimidines; Rats, Wistar; Reverse Transcriptase Inhibitors; Structure-Activity Relationship; Thiophenes

2020
Structure-Based Design and Discovery of Pyridyl-Bearing Fused Bicyclic HIV-1 Inhibitors: Synthesis, Biological Characterization, and Molecular Modeling Studies.
    Journal of medicinal chemistry, 2021, 09-23, Volume: 64, Issue:18

    Topics: Anti-HIV Agents; Cell Line; Drug Design; Heterocyclic Compounds, 2-Ring; HIV Reverse Transcriptase; HIV-1; Humans; Microsomes, Liver; Molecular Dynamics Simulation; Molecular Structure; Mutation; Protein Binding; Pyridines; Reverse Transcriptase Inhibitors; Structure-Activity Relationship

2021