biotin has been researched along with trimethoprim in 8 studies
| Studies (biotin) | Trials (biotin) | Recent Studies (post-2010) (biotin) | Studies (trimethoprim) | Trials (trimethoprim) | Recent Studies (post-2010) (trimethoprim) |
|---|---|---|---|---|---|
| 14,847 | 95 | 3,882 | 6,989 | 845 | 894 |
| Protein | Taxonomy | biotin (IC50) | trimethoprim (IC50) |
|---|---|---|---|
| Chain A, Dihydrofolate reductase | Bacillus anthracis | 77200 | |
| Chain A, dihydrofolate reductase (DHFR) | Bacillus anthracis | 77200 | |
| Dihydrofolate reductase | Mycobacterium avium | 0.2588 | |
| Dihydrofolate reductase | Homo sapiens (human) | 1.8206 | |
| Dihydrofolate reductase | Lacticaseibacillus casei | 0.3493 | |
| Dihydrofolate reductase type 1 | Escherichia coli | 0.25 | |
| Dihydrofolate reductase | Neisseria gonorrhoeae | 0.45 | |
| Thymidylate synthase | Homo sapiens (human) | 3.405 | |
| Dihydrofolate reductase | Staphylococcus aureus | 0.0875 | |
| Thymidylate synthase | Escherichia coli K-12 | 3.405 | |
| Dihydrofolate reductase | Escherichia coli K-12 | 0.6064 | |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Plasmodium falciparum K1 | 0.01 | |
| Dihydrofolate reductase type 1 from Tn4003 | Staphylococcus aureus | 0.023 | |
| Dipeptidyl peptidase 4 | Rattus norvegicus (Norway rat) | 2.7 | |
| Dihydrofolate reductase | Pneumocystis carinii | 0.7061 | |
| Dihydrofolate reductase | Candida albicans | 0.1361 | |
| Dipeptidyl peptidase 4 | Homo sapiens (human) | 2.7 | |
| 5-hydroxytryptamine receptor 2B | Rattus norvegicus (Norway rat) | 0.45 | |
| Metabotropic glutamate receptor 5 | Rattus norvegicus (Norway rat) | 2.73 | |
| Mu-type opioid receptor | Cavia porcellus (domestic guinea pig) | 2.8 | |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Toxoplasma gondii | 3.2206 | |
| Bifunctional dihydrofolate reductase-thymidylate synthase | Plasmodium berghei ANKA | 0.12 | |
| Dihydrofolate reductase | Streptococcus pneumoniae TIGR4 | 0.0297 | |
| Dihydrofolate reductase | Lactococcus lactis subsp. lactis Il1403 | 0.45 | |
| Dihydrofolate reductase | Bacillus anthracis | 4.77 | |
| Dihydrofolate reductase | Rattus norvegicus (Norway rat) | 1.244 | |
| Dihydrofolate reductase | Pneumocystis jirovecii | 0.092 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (25.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 4 (50.00) | 24.3611 |
| 2020's | 1 (12.50) | 2.80 |
| Authors | Studies |
|---|---|
| Andrews, PR; Craik, DJ; Martin, JL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Gibbs, AC | 1 |
| Amyes, SG; Towner, KJ; Young, HK | 1 |
| Reinemer, P; Saito, K; Shimazaki, M; Togame, H; Watanabe, S; Yamato, A | 1 |
| Fu, TY; Huang, SJ; Lin, FL; Tan, KT; Wang, XY; Wu, CC | 1 |
1 review(s) available for biotin and trimethoprim
| Article | Year |
|---|---|
Elements and modulation of functional dynamics.
Topics: Drug Design; Drug Resistance; Entropy; Magnetic Resonance Spectroscopy; Molecular Dynamics Simulation; Mutation; Protein Conformation; Proteins; Structure-Activity Relationship; Thermodynamics | 2014 |
7 other study(ies) available for biotin and trimethoprim
| Article | Year |
|---|---|
Functional group contributions to drug-receptor interactions.
Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship | 1984 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Biotinylated DNA probes for trimethoprim-resistant dihydrofolate reductases types IV and V.
Topics: Biotin; Cloning, Molecular; DNA; DNA Probes; Drug Resistance, Microbial; Nucleic Acid Hybridization; Plasmids; Restriction Mapping; Tetrahydrofolate Dehydrogenase; Trimethoprim | 1988 |
Development of a simple homogeneous assay to screen for inhibitors of N-acetylglucosamine-6-sulfotransferases.
Topics: Adenosine Diphosphate; Animals; Automation; Biotin; Biotinylation; Carbohydrate Sulfotransferases; Cell Line; Drug Combinations; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Glycoconjugates; Glycosides; Humans; Hydrogen-Ion Concentration; Kinetics; Phosphoadenosine Phosphosulfate; Spodoptera; Substrate Specificity; Sulfamonomethoxine; Sulfotransferases; Time Factors; Trimethoprim | 2003 |
Small-Molecule Modulated Affinity-Tunable Semisynthetic Protein Switches.
Topics: Biotin; Fluorescent Dyes; Methotrexate; Nucleic Acids; Proteins; Streptavidin; Sulfonamides; Trimethoprim | 2022 |