Rare congenital deformity syndrome characterized by a combination of five anomalies as a result of neural tube defect. The five anomalies are a midline supraumbilical abdominal wall defect (e.g., OMPHALOCELE), a lower STERNUM defect, a congenital intracardiac defect, an anterior DIAPHRAGM defect, and a diaphragmatic PERICARDIUM defect (e.g., PERICARDIAL EFFUSION). Variants with incomplete and variable combinations of the defects are known. ECTOPIA CORDIS; CLEFT LIP; and CLEFT PALATE are often associated with the syndrome.
| Synonym |
|---|
| Cantrell Haller Ravitch syndrome |
| Cantrell Pentalogy |
| Pentalogy of Cantrell |
| Cantrell's Pentalogy |
| Thoracoabdominal Syndrome |
| Timeframe | Studies, This Condition (%) | All Conditions % |
|---|---|---|
| pre-1990 | 0 (0.00) | 23.3326 |
| 1990's | 0 (0.00) | 12.5806 |
| 2000's | 0 (0.00) | 18.1394 |
| 2010's | 5 (100.00) | 28.8240 |
| 2020's | 0 (0.00) | 9.53 |
| Drug | Indicated | Relationship Strength | Studies | Trials |
|---|---|---|---|---|
| lactic acid | 0 | low | 1 | 0 |
| iohexol | 0 | low | 1 | 0 |
| titanium | 0 | low | 1 | 0 |
| iobitridol | 0 | low | 1 | 0 |
| phenylephrine hydrochloride | 0 | low | 1 | 0 |
| transforming growth factor beta | 0 | low | 1 | 0 |