isoniazid
Hydra: A genus of freshwater polyps in the family Hydridae, order Hydroida, class HYDROZOA. They are of special interest because of their complex organization and because their adult organization corresponds roughly to the gastrula of higher animals.. hydrazide : Compounds derived from oxoacids RkE(=O)l(OH)m (l =/= 0) by replacing -OH by -NRNR2 (R groups are commonly H). (IUPAC). | 2.07 | 1 | 0 | carbohydrazide | antitubercular agent;
drug allergen |
uridine
[no description available] | 3.41 | 1 | 0 | uridines | drug metabolite;
fundamental metabolite;
human metabolite |
pyrroles
1H-pyrrole : A tautomer of pyrrole that has the double bonds at positions 2 and 4.. pyrrole : A five-membered monocyclic heteroarene comprising one NH and four CH units which forms the parent compound of the pyrrole group of compounds. Its five-membered ring structure has three tautomers. A 'closed class'.. azole : Any monocyclic heteroarene consisting of a five-membered ring containing nitrogen. Azoles can also contain one or more other non-carbon atoms, such as nitrogen, sulfur or oxygen. | 5.64 | 3 | 0 | pyrrole;
secondary amine | |
adamantane
Adamantane: A tricyclo bridged hydrocarbon. | 5.05 | 2 | 0 | adamantanes;
polycyclic alkane | |
azomycin
azomycin: RN given refers to parent cpd with specified locant; structure | 4.07 | 1 | 0 | C-nitro compound;
imidazoles | antitubercular agent |
oxazolidin-2-one
Oxazolidinones: Derivatives of oxazolidin-2-one. They represent an important class of synthetic antibiotic agents.. oxazolidin-2-one : An oxazolidinone that is 1,3-oxazolidine with an oxo substituent at position 2.. oxazolidinone : An oxazolidine containing one or more oxo groups. | 5.05 | 2 | 0 | carbamate ester;
oxazolidinone | metabolite |
carbapenems
[no description available] | 4.07 | 1 | 0 | | |
azd2563
posizolid: an antitubercular agent; structure in first source | 3.41 | 1 | 0 | | |
sq-641
SQ-641: a MurX inhibitor with antitubercular activity; structure in first source | 3.41 | 1 | 0 | | |
sq 109
N-geranyl-N'-(2-adamantyl)ethane-1,2-diamine: has antitubercular activity | 4.07 | 1 | 0 | | |
bedaquiline
bedaquiline: a diarylquinoline Antitubercular Agent. bedaquiline : A quinoline-based antimycobacterial drug used (as its fumarate salt) for the treatment of pulmonary multi-drug resistant tuberculosis by inhibition of ATP synthase, an enzyme essential for the replication of the mycobacteria. | 4.07 | 1 | 0 | aromatic ether;
naphthalenes;
organobromine compound;
quinolines;
tertiary alcohol;
tertiary amino compound | antitubercular agent;
ATP synthase inhibitor |
rifamycins
[no description available] | 4.07 | 1 | 0 | | |
piperidines
Piperidines: A family of hexahydropyridines. | 3.41 | 1 | 0 | | |