somatomedin b profile

ID Source	ID
PubMed CID	168069366
MeSH ID	M0066941

Synonym
sulfation factor b
somatomedin b
63774-77-6

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	16 (29.09)	18.7374
1990's	9 (16.36)	18.2507
2000's	17 (30.91)	29.6817
2010's	13 (23.64)	24.3611
2020's	0 (0.00)	2.80

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	1 (1.79%)	6.00%
Case Studies	1 (1.79%)	4.05%
Observational	0 (0.00%)	0.25%
Other	54 (96.43%)	84.16%

Substance	Studies	Classes	Roles	First Year	Last Year	Average Age	Relationship Strength	pre-1990	1990's	2000's	2010's
chlorine	1	halide anion; monoatomic chlorine	cofactor; Escherichia coli metabolite; human metabolite	2011	2011	13.0	low	0	0	0	1
glycine	1	alpha-amino acid; amino acid zwitterion; proteinogenic amino acid; serine family amino acid	EC 2.1.2.1 (glycine hydroxymethyltransferase) inhibitor; fundamental metabolite; hepatoprotective agent; micronutrient; neurotransmitter; NMDA receptor agonist; nutraceutical	2019	2019	5.0	low	0	0	0	1
hydrogen	1	elemental hydrogen; elemental molecule; gas molecular entity	antioxidant; electron donor; food packaging gas; fuel; human metabolite	2012	2012	12.0	low	0	0	0	1
urea	1	isourea; monocarboxylic acid amide; one-carbon compound	Daphnia magna metabolite; Escherichia coli metabolite; fertilizer; flour treatment agent; human metabolite; mouse metabolite; Saccharomyces cerevisiae metabolite	1997	1997	27.0	low	0	1	0	0
hydroxyproline	1	4-hydroxyproline; L-alpha-amino acid zwitterion	human metabolite; mouse metabolite; plant metabolite	1981	1981	43.0	low	1	0	0	0
aspartic acid	1	aspartate family amino acid; aspartic acid; L-alpha-amino acid; proteinogenic amino acid	Escherichia coli metabolite; mouse metabolite; neurotransmitter	2019	2019	5.0	low	0	0	0	1
histidine	1	amino acid zwitterion; histidine; L-alpha-amino acid; polar amino acid zwitterion; proteinogenic amino acid	algal metabolite; Escherichia coli metabolite; human metabolite; micronutrient; mouse metabolite; nutraceutical; Saccharomyces cerevisiae metabolite	2016	2016	8.0	low	0	0	0	1
arginine	2	arginine; glutamine family amino acid; L-alpha-amino acid; proteinogenic amino acid	biomarker; Escherichia coli metabolite; micronutrient; mouse metabolite; nutraceutical	1997	2019	16.0	low	0	1	0	1
cyanogen bromide	2			1991	2007	25.0	low	0	1	1	0
dithiothreitol	1	1,4-dimercaptobutane-2,3-diol; butanediols; dithiol; glycol; thiol	chelator; human metabolite; reducing agent	1997	1997	27.0	low	0	1	0	0
deuterium	1	dihydrogen		2012	2012	12.0	low	0	0	0	1
1,5-i-aedans	1	aminonaphthalenesulfonic acid	fluorescent probe	2009	2009	15.0	low	0	0	1	0
arginyl-glycyl-aspartic acid	3	oligopeptide		1991	2019	22.0	medium	0	2	0	1
proline	1	amino acid zwitterion; glutamine family amino acid; L-alpha-amino acid; proline; proteinogenic amino acid	algal metabolite; compatible osmolytes; Escherichia coli metabolite; micronutrient; mouse metabolite; nutraceutical; Saccharomyces cerevisiae metabolite	1981	1981	43.0	low	1	0	0	0
cysteine	5	cysteinium	fundamental metabolite	1996	2007	20.8	high	0	1	4	0
epidermal growth factor	1			1981	1981	43.0	low	1	0	0	0

Condition	Studies	First Year	Last Year	Average Age	Relationship Strength	pre-1990	1990's	2000's	2010's
Acromegaly	1	1980	1980	44.0	low	1	0	0	0
Acute Confusional Senile Dementia	1	1988	1988	36.0	low	1	0	0	0
Adenohypophyseal Hyposecretion	2	1982	1987	39.5	low	2	0	0	0
Alcohol Abuse	1	1986	1986	38.0	low	1	0	0	0
Alcoholism	1	1986	1986	38.0	low	1	0	0	0
Alzheimer Disease	1	1988	1988	36.0	low	1	0	0	0
Benign Neoplasms	1	2007	2007	17.0	low	0	0	1	0
Body Weight	1	1981	1981	43.0	low	1	0	0	0
Calcification, Pathologic	1	2016	2016	8.0	low	0	0	0	1
Calcinosis	1	2016	2016	8.0	low	0	0	0	1
Cirrhosis, Liver	1	1984	1984	40.0	low	1	0	0	0
Complications, Pregnancy	1	1987	1987	37.0	low	1	0	0	0
Depression, Endogenous	1	1988	1988	36.0	low	1	0	0	0
Depressive Disorder	1	1988	1988	36.0	low	1	0	0	0
Dermatoses	1	2013	2013	11.0	low	0	0	0	1
Diseases of Endocrine System	1	1986	1986	38.0	low	1	0	0	0
Disseminated Superficial Actinic Porokeratosis	1	2013	2013	11.0	low	0	0	0	1
Dwarfism, Growth Hormone Deficiency	1	1980	1980	44.0	low	1	0	0	0
Dwarfism, Pituitary	1	1980	1980	44.0	low	1	0	0	0
Endocrine System Diseases	1	1986	1986	38.0	low	1	0	0	0
Genetic Skin Diseases	1	2013	2013	11.0	low	0	0	0	1
Growth Disorders	1	1983	1983	41.0	low	1	0	0	0
Hyperkeratosis Palmaris et Plantaris	1	2016	2016	8.0	low	0	0	0	1
Hypomelanosis	2	2013	2016	9.5	low	0	0	0	2
Hypopigmentation	2	2013	2016	9.5	low	0	0	0	2
Hypopituitarism	2	1982	1987	39.5	low	2	0	0	0
Inappropriate GH Secretion Syndrome (Acromegaly)	1	1980	1980	44.0	low	1	0	0	0
Insulin Resistance	1	2012	2012	12.0	low	0	0	0	1
Insulin Sensitivity	1	2012	2012	12.0	low	0	0	0	1
Keratoderma Blennorrhagicum	1	2013	2013	11.0	low	0	0	0	1
Keratosis	1	2013	2013	11.0	low	0	0	0	1
Liver Cirrhosis	1	1984	1984	40.0	low	1	0	0	0
Metastase	1	2007	2007	17.0	low	0	0	1	0
Neoplasm Metastasis	1	2007	2007	17.0	low	0	0	1	0
Neoplasms	1	2007	2007	17.0	low	0	0	1	0
Porokeratosis	1	2013	2013	11.0	low	0	0	0	1
Pregnancy	3	1985	1991	36.3	low	2	1	0	0
Skin Diseases	1	2013	2013	11.0	low	0	0	0	1
Stunted Growth	1	1983	1983	41.0	low	1	0	0	0

Radioimmunoassayable serum somatomedin B in normal subjects and in patients with acromegaly and pituitary dwarfism: effects of human growth hormone therapy.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, , Volume: 12, Issue:10, 1980

Circulating levels of insulin-like growth factors 1 and 2 and somatomedin B in alcoholic patients.
Psychiatry research, , Volume: 18, Issue:4, 1986

Insulin-like growth factors and somatomedin B in the cerebrospinal fluid of patients with dementia of the Alzheimer type.
Acta psychiatrica Scandinavica, , Volume: 77, Issue:6, 1988

Association of Cole disease with novel heterozygous mutations in the somatomedin-B domains of the ENPP1 gene: necessary, but not always sufficient.
The British journal of dermatology, , Volume: 174, Issue:5, 2016

Immunoreactive somatomedin B is increased in serum in patients with major depressive disorder.
Acta psychiatrica Scandinavica, , Volume: 78, Issue:5, 1988

Radioimmunoassayable serum somatomedin B in normal subjects and in patients with acromegaly and pituitary dwarfism: effects of human growth hormone therapy.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, , Volume: 12, Issue:10, 1980

Immunoreactive somatomedin B (RIA-B) in the circulation of healthy adults and patients with endocrine disorders.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, , Volume: 18, Issue:10, 1986

Radioimmunological determination of somatomedin B in healthy children and in children with growth disturbances.
Acta endocrinologica, , Volume: 102, Issue:1, 1983

Immunoreactive somatomedin B in the human foetus and in women during pregnancy.
Acta endocrinologica, , Volume: 115, Issue:2, 1987

A screening method for measuring somatomedin B protein binding in serum from children with growth retardation.
Annals of clinical biochemistry, , Volume: 19, Issue:Pt 2, 1982

In silico analysis of the two tandem somatomedin B domains of ENPP1 reveals hints on the homodimerization of the protein.
Journal of cellular physiology, , Volume: 227, Issue:11, 2012

Cole Disease Results from Mutations in ENPP1.
American journal of human genetics, , Oct-03, Volume: 93, Issue:4, 2013

The "so-called" somatomedin B and growth hormone measured by radioimmunoassay in normal and cirrhotic individuals.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, , Volume: 16, Issue:8, 1984

Mapping of the vitronectin-binding site on the urokinase receptor: involvement of a coherent receptor interface consisting of residues from both domain I and the flanking interdomain linker region.
The Journal of biological chemistry, , May-04, Volume: 282, Issue:18, 2007

Homology of placental protein 11 and pea seed albumin 2 with vitronectin.
Biochemical and biophysical research communications, , May-15, Volume: 176, Issue:3, 1991

Immunoreactive somatomedin B in the human foetus and in women during pregnancy.
Acta endocrinologica, , Volume: 115, Issue:2, 1987

Vitronectin--a major cell attachment-promoting protein in fetal bovine serum.
Experimental cell research, , Volume: 160, Issue:2, 1985

Cole Disease Results from Mutations in ENPP1.
American journal of human genetics, , Oct-03, Volume: 93, Issue:4, 2013

Association of Cole disease with novel heterozygous mutations in the somatomedin-B domains of the ENPP1 gene: necessary, but not always sufficient.
The British journal of dermatology, , Volume: 174, Issue:5, 2016

Cole Disease Results from Mutations in ENPP1.
American journal of human genetics, , Oct-03, Volume: 93, Issue:4, 2013

Cole Disease Results from Mutations in ENPP1.
American journal of human genetics, , Oct-03, Volume: 93, Issue:4, 2013

Association of Cole disease with novel heterozygous mutations in the somatomedin-B domains of the ENPP1 gene: necessary, but not always sufficient.
The British journal of dermatology, , Volume: 174, Issue:5, 2016

Cole Disease Results from Mutations in ENPP1.
American journal of human genetics, , Oct-03, Volume: 93, Issue:4, 2013

Cole Disease Results from Mutations in ENPP1.
American journal of human genetics, , Oct-03, Volume: 93, Issue:4, 2013

Radioimmunoassayable serum somatomedin B in normal subjects and in patients with acromegaly and pituitary dwarfism: effects of human growth hormone therapy.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, , Volume: 12, Issue:10, 1980

Circulating levels of insulin-like growth factors 1 and 2 and somatomedin B in alcoholic patients.
Psychiatry research, , Volume: 18, Issue:4, 1986

Insulin-like growth factors and somatomedin B in the cerebrospinal fluid of patients with dementia of the Alzheimer type.
Acta psychiatrica Scandinavica, , Volume: 77, Issue:6, 1988

Autoradiographic comparison of growth factors: influence of growth hormone and somatomedin B on patterns of proline incorporation.
Clinical endocrinology, , Volume: 15, Issue:4, 1981

Association of Cole disease with novel heterozygous mutations in the somatomedin-B domains of the ENPP1 gene: necessary, but not always sufficient.
The British journal of dermatology, , Volume: 174, Issue:5, 2016

Immunoreactive somatomedin B is increased in serum in patients with major depressive disorder.
Acta psychiatrica Scandinavica, , Volume: 78, Issue:5, 1988

Radioimmunoassayable serum somatomedin B in normal subjects and in patients with acromegaly and pituitary dwarfism: effects of human growth hormone therapy.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, , Volume: 12, Issue:10, 1980

Immunoreactive somatomedin B (RIA-B) in the circulation of healthy adults and patients with endocrine disorders.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, , Volume: 18, Issue:10, 1986

Radioimmunological determination of somatomedin B in healthy children and in children with growth disturbances.
Acta endocrinologica, , Volume: 102, Issue:1, 1983

Immunoreactive somatomedin B in the human foetus and in women during pregnancy.
Acta endocrinologica, , Volume: 115, Issue:2, 1987

A screening method for measuring somatomedin B protein binding in serum from children with growth retardation.
Annals of clinical biochemistry, , Volume: 19, Issue:Pt 2, 1982

In silico analysis of the two tandem somatomedin B domains of ENPP1 reveals hints on the homodimerization of the protein.
Journal of cellular physiology, , Volume: 227, Issue:11, 2012

Cole Disease Results from Mutations in ENPP1.
American journal of human genetics, , Oct-03, Volume: 93, Issue:4, 2013

Association of Cole disease with novel heterozygous mutations in the somatomedin-B domains of the ENPP1 gene: necessary, but not always sufficient.
The British journal of dermatology, , Volume: 174, Issue:5, 2016

The "so-called" somatomedin B and growth hormone measured by radioimmunoassay in normal and cirrhotic individuals.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, , Volume: 16, Issue:8, 1984

Mapping of the vitronectin-binding site on the urokinase receptor: involvement of a coherent receptor interface consisting of residues from both domain I and the flanking interdomain linker region.
The Journal of biological chemistry, , May-04, Volume: 282, Issue:18, 2007

Immunoreactive somatomedin B in the human foetus and in women during pregnancy.
Acta endocrinologica, , Volume: 115, Issue:2, 1987

Cole Disease Results from Mutations in ENPP1.
American journal of human genetics, , Oct-03, Volume: 93, Issue:4, 2013

somatomedin b

Description

Cross-References

Synonyms (3)

Research

Studies (55)

Study Types

somatomedin b

Description

Cross-References

Synonyms (3)

Research

Studies (55)

Study Types

Related Drugs (16)

Drugs Researched Together (16)

Related Conditions (39)