| Assay ID | Title | Year | Journal | Article |
|---|
| AID414924 | Agonist activity at human H2 receptor expressed in insect Sf9 cells co-expressing GsalphaS fusion protein assessed as gamma[32P]GTP binding by liquid scintillation counting | 2009 | Journal of medicinal chemistry, Apr-23, Volume: 52, Issue:8
| N(G)-acylated imidazolylpropylguanidines as potent histamine H4 receptor agonists: selectivity by variation of the N(G)-substituent. |
| AID414931 | Intrinsic activity at human H2 receptor expressed in insect Sf9 cells co-expressing GsalphaS fusion protein assessed as gamma[32P]GTP binding at 10 uM by liquid scintillation counting relative to histamine | 2009 | Journal of medicinal chemistry, Apr-23, Volume: 52, Issue:8
| N(G)-acylated imidazolylpropylguanidines as potent histamine H4 receptor agonists: selectivity by variation of the N(G)-substituent. |
| AID414932 | Intrinsic activity at human H3 receptor expressed in insect Sf9 cells co-expressing Gialpha2, Gbeta1gamma2 and RGS4 assessed as gamma[32P]GTP binding at 10 uM by liquid scintillation counting relative to histamine | 2009 | Journal of medicinal chemistry, Apr-23, Volume: 52, Issue:8
| N(G)-acylated imidazolylpropylguanidines as potent histamine H4 receptor agonists: selectivity by variation of the N(G)-substituent. |
| AID183458 | Tested for inhibition of histamine-stimulated gastric acid secretion in the lumen-perfused anesthetized rat expressed as intravenous dose which reduces a near maximal secretion to 50% | 1981 | Journal of medicinal chemistry, Aug, Volume: 24, Issue:8
| 1980 Award in Medicinal Chemistry: Medicinal chemistry and dynamic structure-activity analysis in the discovery of drugs acting at histamine H2 receptors. |
| AID414925 | Agonist activity at human H3 receptor expressed in insect Sf9 cells co-expressing Gialpha2, Gbeta1gamma2 and RGS4 assessed as gamma[32P]GTP binding by liquid scintillation counting | 2009 | Journal of medicinal chemistry, Apr-23, Volume: 52, Issue:8
| N(G)-acylated imidazolylpropylguanidines as potent histamine H4 receptor agonists: selectivity by variation of the N(G)-substituent. |
| AID414933 | Intrinsic activity at human H4 receptor expressed in insect Sf9 cells co-expressing RGS19 fusion protein and Gialpha2, Gbeta1gamma2 assessed as gamma[32P]GTP binding at 10 uM by liquid scintillation counting relative to histamine | 2009 | Journal of medicinal chemistry, Apr-23, Volume: 52, Issue:8
| N(G)-acylated imidazolylpropylguanidines as potent histamine H4 receptor agonists: selectivity by variation of the N(G)-substituent. |
| AID88166 | Histamine H2 receptor agonistic activity in guinea pig right atrium | 1992 | Journal of medicinal chemistry, Aug-21, Volume: 35, Issue:17
| Histamine H2-receptor agonists. Synthesis, in vitro pharmacology, and qualitative structure-activity relationships of substituted 4- and 5-(2-aminoethyl)thiazoles. |
| AID414930 | Intrinsic activity at human H1 receptor expressed in insect Sf9 cells co-expressing RGS4 assessed as gamma[32P]GTP binding at 10 uM by liquid scintillation counting relative to histamine | 2009 | Journal of medicinal chemistry, Apr-23, Volume: 52, Issue:8
| N(G)-acylated imidazolylpropylguanidines as potent histamine H4 receptor agonists: selectivity by variation of the N(G)-substituent. |
| AID414927 | Antagonist activity at human H1 receptor expressed in insect Sf9 cells co-expressing RGS4 assessed as inhibition of histamine-induced gamma[32P]GTP binding by liquid scintillation counting | 2009 | Journal of medicinal chemistry, Apr-23, Volume: 52, Issue:8
| N(G)-acylated imidazolylpropylguanidines as potent histamine H4 receptor agonists: selectivity by variation of the N(G)-substituent. |
| AID414926 | Agonist activity at human H4 receptor expressed in insect Sf9 cells co-expressing RGS19 fusion protein and Gialpha2, Gbeta1gamma2 assessed as gamma[32P]GTP binding by liquid scintillation counting | 2009 | Journal of medicinal chemistry, Apr-23, Volume: 52, Issue:8
| N(G)-acylated imidazolylpropylguanidines as potent histamine H4 receptor agonists: selectivity by variation of the N(G)-substituent. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |