Page last updated: 2024-11-06

pentafluoropyridine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Pentafluoropyridine is a colorless, volatile liquid with a pungent odor. It is a versatile building block in organic synthesis, particularly in the preparation of pharmaceuticals, agrochemicals, and materials science applications. Its synthesis typically involves the fluorination of pyridine, a process that can be achieved using various reagents and conditions. The presence of five fluorine atoms on the pyridine ring imparts unique properties to the molecule, such as high chemical stability, lipophilicity, and electron-withdrawing character. These properties contribute to the compound's utility as a starting material for the development of novel compounds with diverse biological activities and functionalities. Its unique electronic properties, such as its ability to act as a strong electron withdrawing group, make it a key component in the synthesis of pharmaceuticals and agrochemicals. Researchers are also interested in its potential as a precursor for the development of new materials with improved properties, such as high thermal stability and chemical resistance. '

Cross-References

ID SourceID
PubMed CID69690
SCHEMBL ID188694
MeSH IDM0467182

Synonyms (24)

Synonym
pentafluoropyridine ,
pyridine, pentafluoro-
pentafluoropyridine, >=99%
700-16-3
2,3,4,5,6-pentafluoropyridine
AKOS005063396
perfluoropyridine
P0926
einecs 211-839-9
2,3,4,5,6-pentafluoro-pyridine
FT-0619350
SCHEMBL188694
DTXSID70220258
W-104574
c5f5n
F8880-0939
mfcd00006225
Z277540960
SY048914
2,3,4,5,6-perfluoropyridine
AMY12530
PS-10163
EN300-83460
CS-W017731

Research Excerpts

Effects

ExcerptReferenceRelevance
"Some pentafluoropyridine derivatives have been synthesized by the reaction of pentafluoropyridine with appropriate mono and bidentate nucleophile under ultrasonic irradiation. "( Ultrasound promoted facile synthesis of some pentafluoropyridine derivatives at ambient conditions.
Darehkordi, A; Mashak-Shoshtari, M; Ranjbar-Karimi, R, 2011
)
1.14
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (12)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's6 (50.00)29.6817
2010's5 (41.67)24.3611
2020's1 (8.33)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 29.08

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index29.08 (24.57)
Research Supply Index2.64 (2.92)
Research Growth Index4.53 (4.65)
Search Engine Demand Index34.37 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (29.08)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other13 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]