Compounds > ne 21610
Page last updated: 2024-12-11

ne 21610

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID6441194
CHEMBL ID147909
SCHEMBL ID6700365
MeSH IDM0179801

Synonyms (15)

Synonym
ne 21610
CHEMBL147909 ,
(z)-n-[[4-(2-aminoethoxy)-3-methoxyphenyl]methyl]octadec-9-enamide
9-octadecenamide, n-((4-(2-aminoethoxy)-3-methoxyphenyl)methyl)-, (z)-
ne-21610
unii-sw29uo9bhi
n-((4-(2-aminoethoxy)-3-methoxyphenyl)methyl)-9-octadecenamide
118090-17-8
sw29uo9bhi ,
SCHEMBL6700365
aminoethylolvanil
(9z)-n-((4-(2-aminoethoxy)-3-methoxyphenyl)methyl)-9-octadecenamide
9-octadecenamide, n-((4-(2-aminoethoxy)-3-methoxyphenyl)methyl)-, (9z)-
nuvanil
bdbm50470957
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Protein Targets (4)

Activation Measurements

ProteinTaxonomyMeasurementAverageMin (ref.)Avg (ref.)Max (ref.)Bioassay(s)
Transient receptor potential cation channel subfamily V member 1Rattus norvegicus (Norway rat)EC50 (µMol)0.25000.00050.43182.3800AID175476
D(2) dopamine receptorRattus norvegicus (Norway rat)EC50 (µMol)0.25000.00040.32993.9100AID175476
Transient receptor potential cation channel subfamily V member 4Rattus norvegicus (Norway rat)EC50 (µMol)0.25000.03000.33150.9000AID175476
Transient receptor potential cation channel subfamily V member 2Rattus norvegicus (Norway rat)EC50 (µMol)0.25000.03000.45071.7000AID175476
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (5)

Assay IDTitleYearJournalArticle
AID130862In vivo tail-flick latency after peroral administration in mouse as an evaluation of antinociceptive potency1996Journal of medicinal chemistry, Dec-06, Volume: 39, Issue:25
Analogues of capsaicin with agonist activity as novel analgesic agents: structure-activity studies. 4. Potent, orally active analgesics.
AID127624Threshold dose required to cause increase in airway opening pressure in carotid artery of guinea pig after intravenous administration1996Journal of medicinal chemistry, Dec-06, Volume: 39, Issue:25
Analogues of capsaicin with agonist activity as novel analgesic agents: structure-activity studies. 4. Potent, orally active analgesics.
AID130863In vivo tail-flick latency after subcutaneous administration in mouse as an evaluation of antinociceptive potency1996Journal of medicinal chemistry, Dec-06, Volume: 39, Issue:25
Analogues of capsaicin with agonist activity as novel analgesic agents: structure-activity studies. 4. Potent, orally active analgesics.
AID175476Compound tested in vitro for [Ca2+] influx into neonatal rat dorsal root ganglia (DRG)1996Journal of medicinal chemistry, Dec-06, Volume: 39, Issue:25
Analogues of capsaicin with agonist activity as novel analgesic agents: structure-activity studies. 4. Potent, orally active analgesics.
AID129479Compound tested for in vivo writhing antinociceptive assay in mouse after subcutaneous administration1996Journal of medicinal chemistry, Dec-06, Volume: 39, Issue:25
Analogues of capsaicin with agonist activity as novel analgesic agents: structure-activity studies. 4. Potent, orally active analgesics.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's5 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.50

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.50 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.45 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.50)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (20.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other4 (80.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
nonivamide
nonivamide: has effect on sensory neurons. nonivamide : A capsaicinoid that is the carboxamide resulting from the formal condensation of the amino group of 4-hydroxy-3-methoxybenzylamine with the carboxy group of nonanoic acid. It is the active ingredient in many pepper sprays.		1.9910capsaicinoid;
phenols		lachrymator
vanillic acid
Vanillic Acid: A flavoring agent. It is the intermediate product in the two-step bioconversion of ferulic acid to vanillin. (J Biotechnol 1996;50(2-3):107-13).. vanillic acid : A monohydroxybenzoic acid that is 4-hydroxybenzoic acid substituted by a methoxy group at position 3.		1.9910methoxybenzoic acid;
monohydroxybenzoic acid		plant metabolite
capsaicin
ALGRX-4975: an injectable capsaicin (TRPV1 receptor agonist) formulation for longlasting pain relief. capsaicinoid : A family of aromatic fatty amides produced as secondary metabolites by chilli peppers.		4.4751capsaicinoidnon-narcotic analgesic;
TRPV1 agonist;
voltage-gated sodium channel blocker
morphine
Meconium: The thick green-to-black mucilaginous material found in the intestines of a full-term fetus. It consists of secretions of the INTESTINAL GLANDS; BILE PIGMENTS; FATTY ACIDS; AMNIOTIC FLUID; and intrauterine debris. It constitutes the first stools passed by a newborn.		1.9910morphinane alkaloid;
organic heteropentacyclic compound;
tertiary amino compound		anaesthetic;
drug allergen;
environmental contaminant;
geroprotector;
mu-opioid receptor agonist;
opioid analgesic;
plant metabolite;
vasodilator agent;
xenobiotic
olvanil
[no description available]		2.6830methoxybenzenes;
phenols
ConditionIndicatedRelationship StrengthStudiesTrials
Ache
[description not available]		03.7821
Pain
An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.		03.7821
Allodynia
[description not available]		01.9810
Burns
Injuries to tissues caused by contact with heat, steam, chemicals (BURNS, CHEMICAL), electricity (BURNS, ELECTRIC), or the like.		01.9810