Compounds > mitoclomine
Page last updated: 2024-12-06

mitoclomine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Cross-References

ID SourceID
PubMed CID28694
CHEMBL ID2106926
SCHEMBL ID2109906
MeSH IDM0059470

Synonyms (30)

Synonym
1-naphthalenamine, n,n-bis(2-chloroethyl)-4-methoxy-3-methyl-
mitoclomine [inn:ban]
n,n-di-(2-chloroethyl)-4-methoxy-3-methyl-1-naphthylamine
nsc 114575
mitoclominum [inn-latin]
brn 2943587
mitoclomina [inn-spanish]
einecs 241-687-9
1-naphthylamine, n,n-bis(2-chloroethyl)-4-methoxy-3-methyl-
mitoclomine
nsc114575
wba 7707
nsc-114575
n,n-bis(2-chloroethyl)-4-methoxy-3-methyl-1-naphthylamine
17692-54-5
1-naphthalenamine,n-bis(2-chloroethyl)-4-methoxy-3-methyl-
1-naphthylamine,n-bis(2-chloroethyl)-4-methoxy-3-methyl-
n,n-bis(2-chloroethyl)-4-methoxy-3-methylnaphthalen-1-amine
mitoclominum
unii-02dqx562cr
02dqx562cr ,
mitoclomina
CHEMBL2106926
AKOS022181455
mitoclomine [inn]
SCHEMBL2109906
DTXSID30170220
1-naphthalenamine, n,n-bis(2-chloroethyl)-4-methoxy-3-methyl- (9ci)
Q27231519
SB83217
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (4)

TimeframeStudies, This Drug (%)All Drugs %
pre-19904 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (20.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other4 (80.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
chlorambucil
Chlorambucil: A nitrogen mustard alkylating agent used as antineoplastic for chronic lymphocytic leukemia, Hodgkin's disease, and others. Although it is less toxic than most other nitrogen mustards, it has been listed as a known carcinogen in the Fourth Annual Report on Carcinogens (NTP 85-002, 1985). (Merck Index, 11th ed). chlorambucil : A monocarboxylic acid that is butanoic acid substituted at position 4 by a 4-[bis(2-chloroethyl)amino]phenyl group. A chemotherapy drug that can be used in combination with the antibody obinutuzumab for the treatment of chronic lymphocytic leukemia.		7.3620aromatic amine;
monocarboxylic acid;
nitrogen mustard;
organochlorine compound;
tertiary amino compound		alkylating agent;
antineoplastic agent;
carcinogenic agent;
drug allergen;
immunosuppressive agent
1-naphthylamine
1-Naphthylamine: A suspected industrial carcinogen (and listed as such by OSHA). Its N-hydroxy metabolite is strongly carcinogenic and mutagenic.. naphthylamine : A primary arylamine that is naphthalene substituted by an amino group at unspecified position.. 1-naphthylamine : A naphthylamine that is naphthalene substituted by an amino group at position 1.		2.8740naphthylaminehuman xenobiotic metabolite
icig 1163
ICIG 1163: RN given refers to parent cpd; structure in first source		1.9510
rfcnu
RFCNU: RN given refers to ribofuranosyl-cpd		6.9510
cortisone
[no description available]		1.961011-oxo steroid;
17alpha-hydroxy steroid;
20-oxo steroid;
21-hydroxy steroid;
3-oxo-Delta(4) steroid;
C21-steroid;
glucocorticoid;
primary alpha-hydroxy ketone;
tertiary alpha-hydroxy ketone		human metabolite;
mouse metabolite
melphalan
Melphalan: An alkylating nitrogen mustard that is used as an antineoplastic in the form of the levo isomer - MELPHALAN, the racemic mixture - MERPHALAN, and the dextro isomer - MEDPHALAN; toxic to bone marrow, but little vesicant action; potential carcinogen.. melphalan : A phenylalanine derivative comprising L-phenylalanine having [bis(2-chloroethyl)amino group at the 4-position on the phenyl ring.		7.3620L-phenylalanine derivative;
nitrogen mustard;
non-proteinogenic L-alpha-amino acid;
organochlorine compound		alkylating agent;
antineoplastic agent;
carcinogenic agent;
drug allergen;
immunosuppressive agent
ConditionIndicatedRelationship StrengthStudiesTrials
EHS Tumor
[description not available]		01.9510