Page last updated: 2024-12-07
rfcnu
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
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Research Growth
Description
RFCNU: RN given refers to ribofuranosyl-cpd [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 100269 |
| CHEMBL ID | 3989701 |
| SCHEMBL ID | 28141 |
| MeSH ID | M0065246 |
Synonyms (36)
| Synonym |
|---|
| ici-g1105 |
| bofumustine |
| icig 1105 |
| 55102-44-8 |
| nsc-279194 |
| rfcnu |
| i.c.i.g. 1105 |
| bofumustine [inn] |
| bofumustina [inn-spanish] |
| urea, n-(2-chloroethyl)-n'-(2,3-o-(1-methylethylidene)-5-o-(4-nitrobenzoyl)-d-ribofuranosyl)-n-nitroso- |
| furo(3,4-d)-1,3-dioxole, urea deriv. |
| urea, 1-(2-chloroethyl)-1-nitroso-3-ribofuranosyl-, 5'-(p-nitrobenzoate), 2',3'-cyclicacetal with acetone |
| 1-(2-chloroethyl)-3-(2,3-o-isopropylidene-d-ribofuranosyl)-1-nitrosourea 5'-(p-nitrobenzoate) |
| bofumustina [spanish] |
| bofumustinum [inn-latin] |
| (cloro-2-etil)-1-(ribofuranosilisopropilidene-2',3'-paranitrobenzoato)-3-nitrosourea |
| nsc 279194 |
| (chloro-2-ethyl)-1-(ribofuranosylisopropylidene-2'-3'-paranitrobenzoate-5')-3-nitrosourea |
| [4-[[2-chloroethyl(nitroso)carbamoyl]amino]-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]methyl 4-nitrobenzoate |
| [(3ar,6r,6ar)-4-[[2-chloroethyl(nitroso)carbamoyl]amino]-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]methyl 4-nitrobenzoate |
| unii-6p52d0j76b |
| 6p52d0j76b , |
| bofumustinum |
| bofumustina |
| urea, n-(2-chloroethyl)-n'-(2,3-o-(1-methylethylidene)-5-o-(4-nitrobenzoyl)ribofuranosyl)-n-nitroso- |
| 1-(2-chloroethyl)-3-(1'-(5'-4-nitrobenzoyl-2',3'-isopropylidene)-alpha,beta-d-ribofuranosyl)-1-nitrosourea |
| 56194-22-0 |
| n-(2-chloroethyl)-1-ribofuranosyl-2',3'-isopropylidene-5'-(p-nitrobenzoate)-3-nitrosourea |
| SCHEMBL28141 |
| CHEMBL3989701 |
| DTXSID50971579 |
| n-(2-chloroethyl)-n'-[2,3-o-(1-methylethylidene)-5-o-(4-nitrobenzoyl)ribofuranosyl]-n-nitroso-urea |
| icig 1105; nsc 279194; rfcnu |
| Q27265262 |
| DTXSID801023914 |
| AKOS040748042 |
Research Excerpts
Toxicity
| Excerpt | Reference | Relevance |
|---|---|---|
| " In the spleen both drugs provoked a higher toxic effect than in the bone marrow; on Day 1 they decreased the GM-CFUc population by 1 to 2 log." | ( In vivo acute hematotoxicity of N,N'-bis[N-(2-chloroethyl)-N-nitrosocarbamoyl]cystamine (CNCC), a new nitrosourea analog. Blazsek, I; Jasmin, C; Maral, R; Mathé, G, 1984) | 0.27 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Research
Studies (14)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 14 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 1 (6.67%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 14 (93.33%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||