Page last updated: 2024-12-07

rfcnu

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

RFCNU: RN given refers to ribofuranosyl-cpd [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID100269
CHEMBL ID3989701
SCHEMBL ID28141
MeSH IDM0065246

Synonyms (36)

Synonym
ici-g1105
bofumustine
icig 1105
55102-44-8
nsc-279194
rfcnu
i.c.i.g. 1105
bofumustine [inn]
bofumustina [inn-spanish]
urea, n-(2-chloroethyl)-n'-(2,3-o-(1-methylethylidene)-5-o-(4-nitrobenzoyl)-d-ribofuranosyl)-n-nitroso-
furo(3,4-d)-1,3-dioxole, urea deriv.
urea, 1-(2-chloroethyl)-1-nitroso-3-ribofuranosyl-, 5'-(p-nitrobenzoate), 2',3'-cyclicacetal with acetone
1-(2-chloroethyl)-3-(2,3-o-isopropylidene-d-ribofuranosyl)-1-nitrosourea 5'-(p-nitrobenzoate)
bofumustina [spanish]
bofumustinum [inn-latin]
(cloro-2-etil)-1-(ribofuranosilisopropilidene-2',3'-paranitrobenzoato)-3-nitrosourea
nsc 279194
(chloro-2-ethyl)-1-(ribofuranosylisopropylidene-2'-3'-paranitrobenzoate-5')-3-nitrosourea
[4-[[2-chloroethyl(nitroso)carbamoyl]amino]-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]methyl 4-nitrobenzoate
[(3ar,6r,6ar)-4-[[2-chloroethyl(nitroso)carbamoyl]amino]-2,2-dimethyl-3a,4,6,6a-tetrahydrofuro[3,4-d][1,3]dioxol-6-yl]methyl 4-nitrobenzoate
unii-6p52d0j76b
6p52d0j76b ,
bofumustinum
bofumustina
urea, n-(2-chloroethyl)-n'-(2,3-o-(1-methylethylidene)-5-o-(4-nitrobenzoyl)ribofuranosyl)-n-nitroso-
1-(2-chloroethyl)-3-(1'-(5'-4-nitrobenzoyl-2',3'-isopropylidene)-alpha,beta-d-ribofuranosyl)-1-nitrosourea
56194-22-0
n-(2-chloroethyl)-1-ribofuranosyl-2',3'-isopropylidene-5'-(p-nitrobenzoate)-3-nitrosourea
SCHEMBL28141
CHEMBL3989701
DTXSID50971579
n-(2-chloroethyl)-n'-[2,3-o-(1-methylethylidene)-5-o-(4-nitrobenzoyl)ribofuranosyl]-n-nitroso-urea
icig 1105; nsc 279194; rfcnu
Q27265262
DTXSID801023914
AKOS040748042

Research Excerpts

Toxicity

ExcerptReferenceRelevance
" In the spleen both drugs provoked a higher toxic effect than in the bone marrow; on Day 1 they decreased the GM-CFUc population by 1 to 2 log."( In vivo acute hematotoxicity of N,N'-bis[N-(2-chloroethyl)-N-nitrosocarbamoyl]cystamine (CNCC), a new nitrosourea analog.
Blazsek, I; Jasmin, C; Maral, R; Mathé, G, 1984
)
0.27
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (14)

TimeframeStudies, This Drug (%)All Drugs %
pre-199014 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (6.67%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other14 (93.33%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]