menisdaurilide

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

menisdaurilide: from Ouratea reticulata structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Flora	Rank	Flora Definition	Family	Family Definition
Ouratea	genus	[no description available]	Ochnaceae	A plant family of the order THEALES, subclass Dilleniidae, class Magnoliopsida that have evergreen, alternate leaves.[MeSH]

Cross-References

ID Source	ID
PubMed CID	155054
CHEMBL ID	454480
CHEBI ID	81370
MeSH ID	M0404205

Synonyms (9)

Synonym
2(6h)-benzofuranone, 7,7a-dihydro-6-hydroxy-, (6s,7ar)-
menisdaurilide
67765-59-7
C17900
chebi:81370 ,
CHEMBL454480
DTXSID30218030
Q27155307
AKOS040763330

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

Class	Description
benzofurans
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Bioassays (3)

Assay ID	Title	Year	Journal	Article
AID402639	Cytotoxicity against human BC cells by colorimetric method	2005	Journal of natural products, Jul, Volume: 68, Issue:7	Bioactive constituents of the leaves of Phyllanthus polyphyllus var. siamensis.
AID402640	Cytotoxicity against human NCI-H187 cells by colorimetric method	2005	Journal of natural products, Jul, Volume: 68, Issue:7	Bioactive constituents of the leaves of Phyllanthus polyphyllus var. siamensis.
AID402638	Cytotoxicity against human KB cells by colorimetric method	2005	Journal of natural products, Jul, Volume: 68, Issue:7	Bioactive constituents of the leaves of Phyllanthus polyphyllus var. siamensis.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	4 (80.00)	29.6817
2010's	1 (20.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.50

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	12.50 (24.57)
Research Supply Index	1.79 (2.92)
Research Growth Index	4.30 (4.65)
Search Engine Demand Index	0.00 (26.88)
Search Engine Supply Index	0.00 (0.95)

This Compound (12.50)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	0 (0.00%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	5 (100.00%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
ellipticine ellipticine : A organic heterotetracyclic compound that is pyrido[4,3-b]carbazole carrying two methyl substituents at positions 5 and 11.	2.02	1	indole alkaloid; organic heterotetracyclic compound; organonitrogen heterocyclic compound; polycyclic heteroarene	antineoplastic agent; plant metabolite
4-butyrolactone 4-Butyrolactone: One of the FURANS with a carbonyl thereby forming a cyclic lactone. It is an endogenous compound made from gamma-aminobutyrate and is the precursor of gamma-hydroxybutyrate. It is also used as a pharmacological agent and solvent.. tetrahydrofuranone : Any oxolane having an oxo- substituent at any position on the tetrahydrofuran ring.. gamma-butyrolactone : A butan-4-olide that is tetrahydrofuran substituted by an oxo group at position 2.	2.03	1	butan-4-olide	metabolite; neurotoxin
butenolide butenolide: inhibits experimental allergic encephalomyelitis in rats. butenolide : A gamma-lactone that consists of a 2-furanone skeleton and its substituted derivatives.	7.03	1	butenolide
secoisolariciresinol secoisolariciresinol: RN given refers to ((R-(R,R))-isomer); RN for cpd without isomeric designation not available 8/89; precursor of lignans found in human urine; structure given in first source. secoisolariciresinol : A lignan that is butane-1,4-diol in which the 2 and 3 positions are substituted by 4-hydroxy-3-methoxybenzyl groups. (-)-secoisolariciresinol : An enantiomer of secoisolariciresinol having (-)-(2R,3R)-configuration.	2.02	1	secoisolariciresinol	antidepressant; phytoestrogen; plant metabolite
hederagenin [no description available]	2.02	1	dihydroxy monocarboxylic acid; pentacyclic triterpenoid; sapogenin	plant metabolite
dihydrocubebin dihydrocubebin: extract of leaves of Piper guineense Schum. & Thonn.; structure. dihydrocubebin : A glycol that is butane-1,4-diol substituted at the 2- and 3-positions by (1,3-benzodioxol-5-yl)methyl groups (the R,R-configuration).	2.02	1	benzodioxoles; butanediols; glycol; lignan
benzofurans Benzofurans: Compounds that contain a BENZENE ring fused to a furan ring.	2.95	4
3-o-(alpha-l-arabinopyranosyl)hederagenin Akebia saponin PA: isolated from Dipsacus asperoides; structure in first source. hederagenin 3-O-arabinoside : A triterpenoid saponin that is hederagenin attached to an alpha-L-arabinopyranosyl residue at position 3 via a glycosidic linkage.	2.02	1	alpha-L-arabinopyranoside; hydroxy monocarboxylic acid; monosaccharide derivative; pentacyclic triterpenoid; triterpenoid saponin	plant metabolite
securinine securinine: a quinolizine pseudoalkaloid (not from amino acid) from Securinega suffurutiosa or Securinini nitras	7.04	1	indolizines
glycosides [no description available]	2.11	1
virosecurinine virosecurinine: isomer of the securinine group of alkaloids; isolated from plant Securinega virosa	2.04	1
menisdaurin menisdaurin: structure in first source	2.11	1
piperidines Piperidines: A family of hexahydropyridines.	2.04	1

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