Compounds > inosose
Page last updated: 2024-12-04

inosose

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth

Description

inosose: structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID439294
CHEBI ID17811
CHEBI ID81197
SCHEMBL ID4363795
SCHEMBL ID12858507
MeSH IDM0042677

Synonyms (24)

Synonym
CHEBI:17811
C00691
2-inosose
2,4,6/3,5-pentahydroxycyclohexanone
488-64-2
scyllo-inosose
inosose
C17577
myo-inosose-5
ISE ,
(2r,3s,4s,5r,6s)-2,3,4,5,6-pentahydroxycyclohexanone
myo-2-inosose
myo-inosose-2
nsc 55547
myo-inosose
SCHEMBL4363795
CHEBI:81197
SCHEMBL12858507
2-keto-myo-inositol
2-keto-scyllo-inositol
inosose; myo-inosose
Q27155143
VYEGBDHSGHXOGT-ZLIBEWLCSA-N
Q27102637

Research Excerpts

Bioavailability

ExcerptReferenceRelevance
" Identification of small molecule inhibitors that are orally available, have low toxicity and high central nervous system bioavailability is one approach to the potential development of a disease-modifying treatment for Alzheimer's disease."( Modulation of amyloid-beta aggregation and toxicity by inosose stereoisomers.
Cousins, JE; Darabie, AA; Fenili, D; McLaurin, J; Nitz, M; Wu, L, 2008)		0.35
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Pathways (5)

PathwayProteinsCompounds
streptomycin biosynthesis452
myo-, chiro- and scyllo-inositol degradation921
myo-inositol degradation II511
myo-inositol degradation I921
myo-, chiro- and scillo-inositol degradation617

Research

Studies (13)

TimeframeStudies, This Drug (%)All Drugs %
pre-19905 (38.46)18.7374
1990's0 (0.00)18.2507
2000's5 (38.46)29.6817
2010's3 (23.08)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other13 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
acetone
methyl ketone : A ketone of formula RC(=O)CH3 (R =/= H).		1.9410ketone body;
methyl ketone;
propanones;
volatile organic compound		EC 3.5.1.4 (amidase) inhibitor;
human metabolite;
polar aprotic solvent
inositol
Inositol: An isomer of glucose that has traditionally been considered to be a B vitamin although it has an uncertain status as a vitamin and a deficiency syndrome has not been identified in man. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1379) Inositol phospholipids are important in signal transduction.. inositol : Any cyclohexane-1,2,3,4,5,6-hexol.. 1D-chiro-inositol : Belonging to the inositol family of compounds, D-chiro-inositol (DCI) is an isomer of glucose. It is an important secondary messenger in insulin signal transduction.. muco-inositol : An inositol that is cyclohexane-1,2,3,4,5,6-hexol having a (1R,2R,3r,4R,5S,6r)-configuration.		3.93130cyclitol;
hexol
mercaptoethanol
Mercaptoethanol: A water-soluble thiol derived from hydrogen sulfide and ethanol. It is used as a reducing agent for disulfide bonds and to protect sulfhydryl groups from oxidation.		1.9410alkanethiol;
primary alcohol		geroprotector
galactose
galactopyranose : The pyranose form of galactose.		6.9410D-galactose;
galactopyranose		Escherichia coli metabolite;
mouse metabolite
mannose
mannopyranose : The pyranose form of mannose.		2.0110D-aldohexose;
D-mannose;
mannopyranose		metabolite
deuterium
Deuterium: The stable isotope of hydrogen. It has one neutron and one proton in the nucleus.		1.9610dihydrogen
xylose
xylopyranose: structure in first source		6.9610D-xylose
nad
NAD(1-) : An anionic form of nicotinamide adenine dinucleotide arising from deprotonation of the two OH groups of the diphosphate moiety.		2.0510organophosphate oxoanioncofactor;
human metabolite;
hydrogen acceptor;
Saccharomyces cerevisiae metabolite
ConditionIndicatedRelationship StrengthStudiesTrials
Complications of Diabetes Mellitus
[description not available]		02.0410