Page last updated: 2024-12-07
ingenane
Description
Ingenane diterpenoids are a class of natural products with a unique and complex tetracyclic ring system. They are isolated from plants of the genus *Euphorbia*, and exhibit a variety of biological activities, including antitumor, antiviral, and anti-inflammatory properties. Ingenanes are of particular interest to medicinal chemists due to their potent and selective biological activities. Their complex structure poses a significant challenge for chemical synthesis, and researchers are actively developing new strategies to access these compounds for drug discovery and development.'
ingenane: from Euphorbia esula; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| Flora | Rank | Flora Definition | Family | Family Definition |
|---|
| Euphorbia | genus | A large plant genus of the family EUPHORBIACEAE, order Euphorbiales, subclass Rosidae. They have a milky sap and a female flower consisting of a single pistil surrounded by numerous male flowers of one stamen each. Euphorbia hirta is rarely called milkweed but that name is normally used for ASCLEPIAS.[MeSH] | Euphorbiaceae | The spurge family of flowering plants in the order Malpighiales. The family consists of annual and perennial herbs and woody shrubs or trees. Members contain securinine.[MeSH] |
Cross-References
| ID Source | ID |
|---|
| PubMed CID | 115319 |
| MeSH ID | M0523067 |
Synonyms (6)
| Synonym |
|---|
| ingenane |
| 67707-88-4 |
| 1,1,4,7,9-pentamethyldodecahydro-1h-2,8a-methanocyclopenta[a]cyclopropa[e][10]annulene |
| 1h-2,8a-methanocyclopenta(a)cyclopropa(e)cyclodecene, dodecahydro-1,1,4,7,9-pentamethyl-, (1as,2r,4r,5ar,7r,8ar,9r,10ar)- |
| 1h-2,8a-methanocyclopenta(a)cyclopropa(e)cyclodecene, dodecahydro-1,1,4,7,9-pentamethyl-, (1as-(1aalpha,2alpha,4beta,5abeta,7beta,8aalpha,9alpha,10aalpha))- |
| DTXSID10987055 |
Research
Studies (23)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (8.70) | 29.6817 |
| 2010's | 15 (65.22) | 24.3611 |
| 2020's | 6 (26.09) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 21.68
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| Metric | This Compound (vs All) |
|---|
| Research Demand Index | 21.68 (24.57) | | Research Supply Index | 3.22 (2.92) | | Research Growth Index | 5.60 (4.65) | | Search Engine Demand Index | 18.60 (26.88) | | Search Engine Supply Index | 2.00 (0.95) |
| |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 1 (4.17%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 23 (95.83%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |