| Assay ID | Title | Year | Journal | Article |
|---|
| AID362403 | Displacement of [3H]deltorphin2 from delta opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membrane | 2008 | Journal of medicinal chemistry, Aug-28, Volume: 51, Issue:16
| Further studies on lead compounds containing the opioid pharmacophore Dmt-Tic. |
| AID362404 | Displacement of [3H]DAMGO from mu opioid receptor in Sprague-Dawley rat brain P2 synaptosomal membrane | 2008 | Journal of medicinal chemistry, Aug-28, Volume: 51, Issue:16
| Further studies on lead compounds containing the opioid pharmacophore Dmt-Tic. |
| AID362406 | Agonist activity at delta opioid receptor in mouse vas deferens assessed as inhibition of electrically-stimulated muscle contraction | 2008 | Journal of medicinal chemistry, Aug-28, Volume: 51, Issue:16
| Further studies on lead compounds containing the opioid pharmacophore Dmt-Tic. |
| AID362420 | Selectivity ratio of Ki for mu opioid receptor in Sprague-Dawley rat brain to Ki for delta opioid receptor in Sprague-Dawley rat brain | 2008 | Journal of medicinal chemistry, Aug-28, Volume: 51, Issue:16
| Further studies on lead compounds containing the opioid pharmacophore Dmt-Tic. |
| AID73190 | Negative logarithm of the molar concentration of an agonist to produce 50% of the maximum effect in guinea pig ileum (mu receptor) determined by Salvadori et al. | 2002 | Journal of medicinal chemistry, Jan-31, Volume: 45, Issue:3
| Evaluation of the Dmt-Tic pharmacophore: conversion of a potent delta-opioid receptor antagonist into a potent delta agonist and ligands with mixed properties. |
| AID266691 | Binding affinity to mu opioid receptor | 2006 | Journal of medicinal chemistry, Jun-29, Volume: 49, Issue:13
| New 2',6'-dimethyl-L-tyrosine (Dmt) opioid peptidomimetics based on the Aba-Gly scaffold. Development of unique mu-opioid receptor ligands. |
| AID149672 | Binding affinity at Opioid receptor delta 1 using rat brain receptor (P2 synaptosome) assay | 2002 | Journal of medicinal chemistry, Jan-31, Volume: 45, Issue:3
| Evaluation of the Dmt-Tic pharmacophore: conversion of a potent delta-opioid receptor antagonist into a potent delta agonist and ligands with mixed properties. |
| AID266695 | Agonist activity at mu opioid receptor by guinea pig ileum assay | 2006 | Journal of medicinal chemistry, Jun-29, Volume: 49, Issue:13
| New 2',6'-dimethyl-L-tyrosine (Dmt) opioid peptidomimetics based on the Aba-Gly scaffold. Development of unique mu-opioid receptor ligands. |
| AID362407 | Antagonist activity at delta opioid receptor in mouse vas deferens assessed as effect on deltorphin 2-induced response | 2008 | Journal of medicinal chemistry, Aug-28, Volume: 51, Issue:16
| Further studies on lead compounds containing the opioid pharmacophore Dmt-Tic. |
| AID392175 | Selectivity ratio of Ki for Sprague-Dawley rat mu opioid receptor to Ki for Sprague-Dawley rat delta opioid receptor | 2009 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 19, Issue:2
| Conformationally constrained opioid ligands: the Dmt-Aba and Dmt-Aia versus Dmt-Tic scaffold. |
| AID392173 | Displacement of [3H]DAMGO from mu opioid receptor in Sprague-Dawley rat brain synaptosomal membranes | 2009 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 19, Issue:2
| Conformationally constrained opioid ligands: the Dmt-Aba and Dmt-Aia versus Dmt-Tic scaffold. |
| AID266690 | Binding affinity to delta opioid receptor | 2006 | Journal of medicinal chemistry, Jun-29, Volume: 49, Issue:13
| New 2',6'-dimethyl-L-tyrosine (Dmt) opioid peptidomimetics based on the Aba-Gly scaffold. Development of unique mu-opioid receptor ligands. |
| AID105932 | Negative logarithm of the molar concentration required to double the agonist concentration to achieve the original response in mu receptor from mouse vas deferens (MVD) | 2002 | Journal of medicinal chemistry, Jan-31, Volume: 45, Issue:3
| Evaluation of the Dmt-Tic pharmacophore: conversion of a potent delta-opioid receptor antagonist into a potent delta agonist and ligands with mixed properties. |
| AID392177 | Antagonist activity at delta opioid receptor in mouse assessed as effect on electrically evoked vas-deferens contraction by MVD test | 2009 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 19, Issue:2
| Conformationally constrained opioid ligands: the Dmt-Aba and Dmt-Aia versus Dmt-Tic scaffold. |
| AID392178 | Agonist activity at mu opioid receptor in Hartley guinea pig assessed as inhibition of electrically evoked ileum contraction by GPI test | 2009 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 19, Issue:2
| Conformationally constrained opioid ligands: the Dmt-Aba and Dmt-Aia versus Dmt-Tic scaffold. |
| AID151611 | Binding affinity for rat brain P2 synaptosome Opioid receptor mu 1 | 2002 | Journal of medicinal chemistry, Jan-31, Volume: 45, Issue:3
| Evaluation of the Dmt-Tic pharmacophore: conversion of a potent delta-opioid receptor antagonist into a potent delta agonist and ligands with mixed properties. |
| AID266693 | Selectivity for delta opioid receptor over mu opioid receptor | 2006 | Journal of medicinal chemistry, Jun-29, Volume: 49, Issue:13
| New 2',6'-dimethyl-L-tyrosine (Dmt) opioid peptidomimetics based on the Aba-Gly scaffold. Development of unique mu-opioid receptor ligands. |
| AID392172 | Displacement of [3H]DPDPE from delta opioid receptor in Sprague-Dawley rat brain synaptosomal membranes | 2009 | Bioorganic & medicinal chemistry letters, Jan-15, Volume: 19, Issue:2
| Conformationally constrained opioid ligands: the Dmt-Aba and Dmt-Aia versus Dmt-Tic scaffold. |
| AID1346364 | Human mu receptor (Opioid receptors) | 2012 | British journal of anaesthesia, Feb, Volume: 108, Issue:2
| Pharmacological characterization of the bifunctional opioid ligand H-Dmt-Tic-Gly-NH-Bzl (UFP-505). |
| AID1346364 | Human mu receptor (Opioid receptors) | 2018 | British journal of pharmacology, 07, Volume: 175, Issue:14
| In vitro and in vivo characterization of the bifunctional μ and δ opioid receptor ligand UFP-505. |
| AID1346361 | Human delta receptor (Opioid receptors) | 2012 | British journal of anaesthesia, Feb, Volume: 108, Issue:2
| Pharmacological characterization of the bifunctional opioid ligand H-Dmt-Tic-Gly-NH-Bzl (UFP-505). |
| AID1346361 | Human delta receptor (Opioid receptors) | 2018 | British journal of pharmacology, 07, Volume: 175, Issue:14
| In vitro and in vivo characterization of the bifunctional μ and δ opioid receptor ligand UFP-505. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |