Page last updated: 2024-10-15
goadsporin
Description
goadsporin: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
ID Source | ID |
PubMed CID | 139586753 |
MeSH ID | M0417079 |
Synonyms (1)
Research Excerpts
Overview
Goadsporin is a linear azole containing peptide that is biosynthesized via a ribosome-mediated pathway in Streptomyces sp. It is a thiopeptide containing thiazole and oxazole heterocyclic rings.
Excerpt | Reference |
"Goadsporin is a chemical substance isolated from Streptomyces sp." | ( Novel antibiotic screening methods to awaken silent or cryptic secondary metabolic pathways in actinomycetes. Onaka, H, 2017) |
"Goadsporin is a linear azole containing peptide that is biosynthesized via a ribosome-mediated pathway in Streptomyces sp." | ( Genetic approaches to generate hyper-producing strains of goadsporin: the relationships between productivity and gene duplication in secondary metabolite biosynthesis. Asamizu, S; Furumai, T; Haginaka, K; Igarashi, Y; Onaka, H; Ozaki, T, 2014) |
"Goadsporin (GS) is a member of ribosomally synthesized and post-translationally modified peptides (RiPPs), containing an N-terminal acetyl moiety, six azoles and two dehydroalanines in the peptidic main chain. " | ( Dissection of goadsporin biosynthesis by in vitro reconstitution leading to designer analogues expressed in vivo. Asamizu, S; Goto, Y; Hayashi, S; Ikeda, H; Onaka, H; Ozaki, T; Shimomura, M; Suga, H; Sugai, Y; Yamashita, K, 2017) |
"Goadsporin is a thiopeptide containing thiazole and oxazole heterocyclic rings." | ( Biosynthesis of indolocarbazole and goadsporin, two different heterocyclic antibiotics produced by actinomycetes. Onaka, H, 2009) |
"Goadsporin is an oligopeptide consisting of 19 amino acids with the molecular formula C72H97N19020S2." | ( Goadsporin, a chemical substance which promotes secondary metabolism and morphogenesis in streptomycetes. I. Purification and characterization. Furumai, T; Igarashi, Y; Onaka, H; Sato, Y; Tabata, H, 2001) |
Research
Studies (10)
Timeframe | Studies, This Drug (%) | All Drugs % |
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 4 (40.00) | 29.6817 |
2010's | 6 (60.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
Trials | 0 (0.00%) | 5.53% |
Reviews | 3 (30.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 7 (70.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |