Compounds > ethoxynonafluorobutane
Page last updated: 2024-11-08

ethoxynonafluorobutane

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

ethoxynonafluorobutane: used in HPLC [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID206000
SCHEMBL ID37807
MeSH IDM0404070

Synonyms (31)

Synonym
butane, 1-ethoxy-1,1,2,2,3,3,4,4,4-nonafluoro-
1-ethoxy-1,1,2,2,3,3,4,4,4-nonafluorobutane
813458-04-7
nonafluorobutyl ethyl ether
ethyl perfluorobutyl ether
ethyl nonafluorobutyl ether
AKOS007930484
ethoxynonafluorobutane
520bw6fq5u ,
unii-520bw6fq5u
163702-05-4
1-(ethoxy)nonafluorobutane
butane, ethoxynonafluoro-
FT-0676097
novec hfe 7200
ethyl perfluorobutyl ether [inci]
(perfluorobutoxy)ethane
SCHEMBL37807
c4f9oc2h5
hfe-7200
DTXSID0073118
mfcd01862062
ethyl nonafluorobutyl ether (mixture of isomers)
J-010077
hfe-569sf2 (7200)
1-ethoxy-nonafluorobutane
butane,1-ethoxy-1,1,2,2,3,3,4,4,4-nonafluoro-
Q27260938
ethylnonafluorobutylether
AS-75548
F87164

Research Excerpts

Effects

ExcerptReferenceRelevance
"Ethoxynonafluorobutane (ENFB) has been used as a component of new biphasic solvent mixtures. "( Retention of fluorinated chiral selectors in biphasic fluorinated solvent systems and its application to the separation of enantiomers by countercurrent chromatography.
Minguillón, C; Pérez, AM, 2010)		1.8

Toxicity

ExcerptReferenceRelevance
" Thus, completely substituting the main mobile phase component of a normal-phase LC solvent for an environmentally friendly, nonflammable fluorocarbon-ether as a safe and effective solvent must be thoroughly evaluated before it can be recommended for enantioselective separations with API-MS detection."( Evaluation of ethoxynonafluorobutane as a safe and environmentally friendly solvent for chiral normal-phase LC-atmospheric pressure chemical ionization/electrospray ionization-mass spectrometry.
Armstrong, DW; Desai, M; Ding, J, 2005)		0.69

Pharmacokinetics

ExcerptReferenceRelevance
"The stereoselective determination of stereoisomers in biological samples provides vital information on stereospecific metabolism and pharmacokinetic profiles of the drugs."( Development and implementation of a stereoselective normal-phase liquid chromatography-tandem mass spectrometry method for the determination of intrinsic metabolic clearance in human liver microsomes.
Caporuscio, C; D'Arienzo, C; Dai, J; Rose, A; Santella, J; Tymiak, AA; Wang-Iverson, DB; Witkusa, M; Zhang, Y, 2008)		0.35
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's5 (71.43)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 19.82

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index19.82 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.27 (4.65)
Search Engine Demand Index15.26 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (19.82)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
leucine
Leucine: An essential branched-chain amino acid important for hemoglobin formation.. leucine : A branched-chain amino acid that consists of glycine in which one of the hydrogens attached to the alpha-carbon is substituted by an isobutyl group.		2.0510amino acid zwitterion;
L-alpha-amino acid;
leucine;
proteinogenic amino acid;
pyruvate family amino acid		algal metabolite;
Escherichia coli metabolite;
human metabolite;
mouse metabolite;
plant metabolite;
Saccharomyces cerevisiae metabolite
butane
butane : A straight chain alkane composed of 4 carbon atoms.		2.0810alkane;
gas molecular entity		food propellant;
refrigerant
2-methylpentane
Hexanes: Six-carbon saturated hydrocarbon group of the methane series. Include isomers and derivatives. Various polyneuropathies are caused by hexane poisoning.		2.0210alkane
perfluorodecalin
perfluorodecalin: RN given refers to parent cpd without isomeric designation. perfluorodecalin : A fluorocarbon that is decalin in which every hydrogen is replaced by fluorine. Capable of dissolving large quantities of oxygen, it has been used as the basis of an artificial blood substitute.		2.0810fluorocarbonblood substitute;
solvent
perflubron
perflubron: potential anti-obesity compound; reduces food adsorption; 8-carbon perfluorocarbon radiopaque compound; an oral contrast agent for use with MRI to enhance delineation of the bowel distinguishing it from adjacent organs. perflubron : A haloalkane that is perfluorooctane in which a fluorine attached to one of the terminal carbons has been replaced by a bromine.		2.0810haloalkane;
organobromine compound;
perfluorinated compound		blood substitute;
radioopaque medium
muscone
muscone: structure in first source		2.0310
n-(3,5-dinitrobenzoyl)leucine
N-(3,5-dinitrobenzoyl)leucine: RN given for (L)-Leu-isomer		2.0510
ConditionIndicatedRelationship StrengthStudiesTrials