Compounds > epiboxidine
Page last updated: 2024-12-11

epiboxidine

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

epiboxidine: an isoxazole analog of epibatidine; less toxic than epibatidine; structure given in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID5747670
SCHEMBL ID20741469
MeSH IDM0277238

Synonyms (19)

Synonym
188895-96-7
unii-xi646l2arj
xi646l2arj ,
exo-2-(3-methyl-5-isoxazolyl)-7-azabicyclo(2.2.1)heptane
(+-)-epiboxidine
7-azabicyclo(2.2.1)heptane, 2-(3-methyl-5-isoxazolyl)-, exo-
epiboxidine
(+/-)-epiboxidine
DTXSID20172258
rel-(1r,2s,4s)-2-(3-methyl-5-isoxazolyl)-7-azabicyclo(2.2.1)heptane
7-azabicyclo(2.2.1)heptane, 2-(3-methyl-5-isoxazolyl)-, (1r,2s,4s)-rel-
Q5382428
epiboxidine hcl
5-[(1r,2s,4s)-7-azabicyclo[2.2.1]heptan-2-yl]-3-methyl-1,2-oxazole
SCHEMBL20741469
CS-0173498
HY-138953
7-azabicyclo[2.2.1]heptane, 2-(3-methyl-5-isoxazolyl)-, (1r,2s,4s)-rel-
rel-5-((1r,2s,4s)-7-azabicyclo[2.2.1]heptan-2-yl)-3-methylisoxazole

Research Excerpts

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's4 (57.14)29.6817
2010's2 (28.57)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 18.00

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index18.00 (24.57)
Research Supply Index2.08 (2.92)
Research Growth Index4.90 (4.65)
Search Engine Demand Index10.37 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (18.00)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other7 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
n-heptane
Heptanes: Seven-carbon alkanes with the formula C7H16.. heptane : A straight-chain alkane with seven carbon atoms. It has been found in Jeffrey pine (Pinus jeffreyi).		2.0310alkane;
volatile organic compound		non-polar solvent;
plant metabolite
isoxazoles
Isoxazoles: Azoles with an OXYGEN and a NITROGEN next to each other at the 1,2 positions, in contrast to OXAZOLES that have nitrogens at the 1,3 positions.. isoxazole : A monocyclic heteroarene with a structure consisting of a 5-membered ring containing three carbon atoms and an oxygen and nitrogen atom adjacent to each other. It is the parent of the class of isoxazoles.. isoxazoles : Oxazoles in which the N and O atoms are adjacent.		3.4270isoxazoles;
mancude organic heteromonocyclic parent;
monocyclic heteroarene
nicotine
(S)-nicotine : A 3-(1-methylpyrrolidin-2-yl)pyridine in which the chiral centre has S-configuration. The naturally occurring and most active enantiomer of nicotine, isolated from Nicotiana tabacum.		1.99103-(1-methylpyrrolidin-2-yl)pyridineanxiolytic drug;
biomarker;
immunomodulator;
mitogen;
neurotoxin;
nicotinic acetylcholine receptor agonist;
peripheral nervous system drug;
phytogenic insecticide;
plant metabolite;
psychotropic drug;
teratogenic agent;
xenobiotic
epibatidine
epibatidine: a powerful, though toxic, pain killer produced by the poison arrow frog, Epipedobates tricolor; structure given in first source; more potent than morphine but acts at nicotine rather than opiate receptors		7.4320
3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole
3-methyl-5-(1-methyl-2-pyrrolidinyl)isoxazole: structure in first source		1.9910
aza-pinacol
aza-pinacol: structure in first source		2.0310
ConditionIndicatedRelationship StrengthStudiesTrials