Compounds > dihydrosafrole
Page last updated: 2024-12-05

dihydrosafrole

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID7197
CHEBI ID82319
SCHEMBL ID429483
MeSH IDM0108494

Synonyms (50)

Synonym
benzene, 1,2-(methylenedioxy)-4-propyl-
1,3-benzodioxole, 5-propyl-
nsc27867
94-58-6
[1,2-(methylenedioxy)-4-propyl]benzene
wln: t56 bo do chj g3
2',3'-dihydrosafrole
4-propyl-1,2-(methylenedioxy)benzene
1, 5-propyl-
dihydroisosafrole
dihydrosafrol
benzene,2-(methylenedioxy)-4-propyl-
dihydrosafrole
5-propyl-1,3-benzodioxole
safrole, dihydro-
nsc-33707
nsc-27867
nsc33707
1,2-(methylenedioxy)-4-propylbenzene
nsc 27867
ccris 244
ai3-03435
rcra waste number u090
benzene, 1,2-methylenedioxy-4-propyl-
hsdb 2939
brn 0131188
4-propyl-1,2-methylenedioxybenzene
einecs 202-344-9
1-(3,4-methylenedioxyphenyl)propane
rcra waste no. u090
AKOS000276810
C19229
ec 202-344-9
5-19-01-00473 (beilstein handbook reference)
unii-2ml63plh7g
2ml63plh7g ,
1,2-(methylenedioxy)-4-propylbenzene [hsdb]
dihydrosafrole [iarc]
dihydrosafrole (prohibited) [fhfi]
SCHEMBL429483
CHEBI:82319
2-(3,4-methylenedioxyphenyl)ethyl methane
3,4-methylenedioxy phenylpropane
W-100191
5-propylbenzo[d][1,3]dioxole
DTXSID7020475
3,4-methylene-dioxyphenylpropane
dihydrosafrol 10 microg/ml in methanol
Q27155872
1,3-benzodioxole-5-propyl

Research Excerpts

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Drug Classes (1)

ClassDescription
benzodioxoles
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (7)

TimeframeStudies, This Drug (%)All Drugs %
pre-19906 (85.71)18.7374
1990's1 (14.29)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 25.42

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index25.42 (24.57)
Research Supply Index2.20 (2.92)
Research Growth Index4.29 (4.65)
Search Engine Demand Index26.67 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (25.42)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other8 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
benzo(a)pyrene
Benzo(a)pyrene: A potent mutagen and carcinogen. It is a public health concern because of its possible effects on industrial workers, as an environmental pollutant, an as a component of tobacco smoke.. benzo[a]pyrene : An ortho- and peri-fused polycyclic arene consisting of five fused benzene rings.		1.9710ortho- and peri-fused polycyclic arenecarcinogenic agent;
mouse metabolite
beta-naphthoflavone
beta-Naphthoflavone: A polyaromatic hydrocarbon inducer of P4501A1 and P4501A2 cytochromes. (Proc Soc Exp Biol Med 1994 Dec:207(3):302-308). beta-naphthoflavone : An extended flavonoid resulting from the formal fusion of a benzene ring with the f side of flavone.		2.3720extended flavonoid;
naphtho-gamma-pyrone;
organic heterotricyclic compound		aryl hydrocarbon receptor agonist
ethoxyresorufin
ethoxyresorufin: structure		6.9710phenoxazine
phenobarbital
Phenobarbital: A barbituric acid derivative that acts as a nonselective central nervous system depressant. It potentiates GAMMA-AMINOBUTYRIC ACID action on GABA-A RECEPTORS, and modulates chloride currents through receptor channels. It also inhibits glutamate induced depolarizations.. phenobarbital : A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by ethyl and phenyl groups.		1.9610barbituratesanticonvulsant;
drug allergen;
excitatory amino acid antagonist;
sedative
safrole
Safrole: A member of the BENZODIOXOLES that is a constituent of several VOLATILE OILS, notably SASSAFRAS oil. It is a precursor in the synthesis of the insecticide PIPERONYL BUTOXIDE and the drug N-methyl-3,4-methylenedioxyamphetamine (MDMA).. safrole : A member of the class of benzodioxoles that is 1,3-benzodioxole which is substituted by an allyl group at position 5. It is found in several plants, including black pepper, cinnamon and nutmeg, and is present in several essential oils, notably that of sassafras. It has insecticidal properties and has been used as a topical antiseptic. Although not thought to pose a significant carcinogenic risk to humans, findings of weak carcinogenicity in rats have resulted in the banning of its (previously widespread) use in perfumes and soaps, and as a food additive.		3.3470benzodioxolesflavouring agent;
insecticide;
metabolite;
plant metabolite
piperonyl butoxide
[no description available]		6.9810benzodioxolespesticide synergist
ethylene
Plastipore: high density polyethylene sponge biocompatible material; used as posts in dental bridges		6.9310alkene;
gas molecular entity		plant hormone;
refrigerant
n-propylbenzene
n-propylbenzene: RN given refers to parent cpd. propylbenzene : An alkylbenzene that is benzene having one of its aromatic hydrogens substituted by a propyl group.		1.9310alkylbenzene
acridines
Acridines: Compounds that include the structure of acridine.. acridine : A polycyclic heteroarene that is anthracene in which one of the central CH groups is replaced by a nitrogen atom.		1.9310acridines;
mancude organic heterotricyclic parent;
polycyclic heteroarene		genotoxin
1-phenylimidazole
1-phenylimidazole: ligand for cytochrome P-450 & inhibitor of microsomal oxidation		1.9710
isosafrole
isosafrole: RN given refers to cpd without isomeric designation		6.9610benzodioxoles
nadp
[no description available]		1.9710
ConditionIndicatedRelationship StrengthStudiesTrials