Page last updated: 2024-11-12
coronarin e
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Description
coronarin E: structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 9971144 |
| CHEMBL ID | 109252 |
| MeSH ID | M0462751 |
Synonyms (11)
| Synonym |
|---|
| CHEMBL109252 |
| coronarin e |
| coranorin e |
| 117591-81-8 |
| AKOS032948621 |
| 3-(ethoxy(ethyl)amino)propan-1-ol |
| 3-[(e)-2-[(1s,4as,8as)-5,5,8a-trimethyl-2-methylidene-3,4,4a,6,7,8-hexahydro-1h-naphthalen-1-yl]ethenyl]furan |
| HY-N3633 |
| CS-0023969 |
| FS-10193 |
| F92924 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (10)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID440898 | Cytotoxicity against human A375 cells by MTT assay | 2009 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 19, Issue:21 | Phytochemical investigation of labdane diterpenes from the rhizomes of Hedychium spicatum and their cytotoxic activity. |
| AID440896 | Cytotoxicity against human HL60 cells by MTT assay | 2009 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 19, Issue:21 | Phytochemical investigation of labdane diterpenes from the rhizomes of Hedychium spicatum and their cytotoxic activity. |
| AID477859 | Induction of fetal heamoglobin level in human K562 cells assessed as increase in enhanced-GFP expression under the control of gamma-globin promoter at 5 to 100 uM after 5 days by flow cytometry | 2010 | Journal of natural products, Apr-23, Volume: 73, Issue:4 | Labdane diterpenes from the aerial parts of Curcuma comosa enhance fetal hemoglobin production in an erythroid cell line. |
| AID39128 | In vitro cytotoxicity of compound was measured on murine melanoma (B16) cells. | 1998 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 8, Issue:23 | A concise synthesis and in vitro cytotoxicity of new labdane diterpenes. |
| AID477856 | Cytotoxicity against human K562 cells assessed as cell viability at 5 uM | 2010 | Journal of natural products, Apr-23, Volume: 73, Issue:4 | Labdane diterpenes from the aerial parts of Curcuma comosa enhance fetal hemoglobin production in an erythroid cell line. |
| AID440899 | Cytotoxicity against human A549 cells by MTT assay | 2009 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 19, Issue:21 | Phytochemical investigation of labdane diterpenes from the rhizomes of Hedychium spicatum and their cytotoxic activity. |
| AID200824 | In vitro cytotoxicity of compound was measured on human gastric adenocarcinoma (SNU-1) cells. | 1998 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 8, Issue:23 | A concise synthesis and in vitro cytotoxicity of new labdane diterpenes. |
| AID152272 | In vitro cytotoxicity of compound was measured on murine lymphocytic leukemia (P-388) cells. | 1998 | Bioorganic & medicinal chemistry letters, Dec-01, Volume: 8, Issue:23 | A concise synthesis and in vitro cytotoxicity of new labdane diterpenes. |
| AID477853 | Induction of fetal heamoglobin level in human K562 cells assessed as increase in enhanced GFP expression under the control of gamma-globin promoter at 5 uM after 5 days by flow cytometry | 2010 | Journal of natural products, Apr-23, Volume: 73, Issue:4 | Labdane diterpenes from the aerial parts of Curcuma comosa enhance fetal hemoglobin production in an erythroid cell line. |
| AID440897 | Cytotoxicity against human THP1 cells by MTT assay | 2009 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 19, Issue:21 | Phytochemical investigation of labdane diterpenes from the rhizomes of Hedychium spicatum and their cytotoxic activity. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (6)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 4 (66.67) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 12.99
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.99) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 6 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||