Bromotrifluoroacetone (CF3COCH2Br) is a highly reactive and electrophilic compound with a variety of applications in organic synthesis. Its synthesis typically involves the reaction of trifluoroacetone with bromine in the presence of a catalyst, such as aluminum chloride. Due to its electrophilicity, bromotrifluoroacetone is a valuable reagent for the introduction of trifluoromethyl groups into organic molecules, which can significantly alter their properties, including reactivity, stability, and biological activity. Bromotrifluoroacetone is also a valuable building block for the synthesis of various pharmaceuticals, agrochemicals, and other specialty chemicals. Its reactivity and potential for functionalization make it an attractive target for research in diverse areas, including drug discovery, materials science, and synthetic chemistry.'
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bromotrifluoroacetone: specific reagent for active site cysteines of rabbit muscle GPD alkylation [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 79008 |
| SCHEMBL ID | 71390 |
| MeSH ID | M0045261 |
| Synonym |
|---|
| LS-12948 |
| einecs 207-071-9 |
| unii-53rev65e85 |
| 53rev65e85 , |
| 3,3,3-trifluorobromoacetone |
| 1-bromo-3,3,3-trifluoroacetone |
| 3-bromo-1,1,1-trifluoropropanone |
| 3-bromo-1,1,1-trifluoroacetone |
| 431-35-6 |
| inchi=1/c3h2brf3o/c4-1-2(8)3(5,6)7/h1h |
| bromotrifluoroacetone |
| 3-bromo-1,1,1-trifluoroacetone, 98% |
| 3-bromo-1,1,1-trifluoro-2-propanone |
| B1240 |
| 1-bromo-3,3,3-trifluoro-2-propanone |
| 3-bromo-1,1,1-trifluoropropan-2-one |
| AKOS000119373 |
| STL138411 |
| FT-0615120 |
| 1,1,1-trifluoro-3-bromopropanone |
| SCHEMBL71390 |
| 3-bromo-1,1,1-trifluoro-propan-2-one |
| 1,1,1-trifluoro-3-bromoacetone |
| 1,1,1-trifluoro-3-bromo-acetone |
| 3-bromo-1,1, 1-trifluoroacetone |
| 1-bromo-3,3,3-trifluoropropan-2-one |
| bromo-1,1,1-trifluoroacetone |
| bromotrifloroacetone |
| bromo-3,3,3-trifluoropropanone |
| cf3coch2br |
| Q-102554 |
| 2-propanone, 3-bromo-1,1,1-trifluoro- |
| F0001-1189 |
| DTXSID30195690 |
| mfcd00039237 |
| H10738 |
| c3h2brf3o |
| AMY6805 |
| CS-W013229 |
| EN300-20482 |
| PD193105 |
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 6 (66.67) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.05) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 9 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||