1-methyl-4-piperidyl 4'-fluorobenzoate: unsuccessful radiotracer of acetylcholinesterase; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
| ID Source | ID |
|---|---|
| PubMed CID | 128156 |
| CHEMBL ID | 37274 |
| SCHEMBL ID | 1844575 |
| MeSH ID | M0268726 |
| Synonym |
|---|
| TIMTEC1_008350 |
| BAS 05948144 |
| AO-365/41690489 |
| 1-methyl-4-piperidinyl 4-fluorobenzoate |
| 1-methylpiperidin-4-yl 4-fluorobenzoate |
| STK182784 |
| m4p 4'-fluorobenzoate |
| HMS1557L12 |
| CHEMBL37274 |
| AKOS000650159 |
| (1-methylpiperidin-4-yl) 4-fluorobenzoate |
| 102698-53-3 |
| 1-methyl-4-piperidyl 4'-fluorobenzoate |
| SCHEMBL1844575 |
| DTXSID90145459 |
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID588519 | A screen for compounds that inhibit viral RNA polymerase binding and polymerization activities | 2011 | Antiviral research, Sep, Volume: 91, Issue:3 | High-throughput screening identification of poliovirus RNA-dependent RNA polymerase inhibitors. |
| AID540299 | A screen for compounds that inhibit the MenB enzyme of Mycobacterium tuberculosis | 2010 | Bioorganic & medicinal chemistry letters, Nov-01, Volume: 20, Issue:21 | Synthesis and SAR studies of 1,4-benzoxazine MenB inhibitors: novel antibacterial agents against Mycobacterium tuberculosis. |
| AID139240 | Analgesic activity assayed with the mouse hotplate method | 1982 | Journal of medicinal chemistry, Feb, Volume: 25, Issue:2 | Quantitative structure-activity relationships of aromatic esters of 1-methyl-4-piperidinol as analgesics. |
| AID1135667 | Analgesic activity in sc dosed mouse by hot-plate method | 1978 | Journal of medicinal chemistry, Jul, Volume: 21, Issue:7 | Aromatic esters of nonquaternary carbon-4 piperidinols as analgesics. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 1 (20.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.
| This Compound (12.63) All Compounds (24.57) |
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 5 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||