Page last updated: 2024-09-03

1-methyl-4-piperidyl 4'-fluorobenzoate and meperidine

1-methyl-4-piperidyl 4'-fluorobenzoate has been researched along with meperidine in 1 studies

*Meperidine: A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration. [MeSH]

*Meperidine: A narcotic analgesic that can be used for the relief of most types of moderate to severe pain, including postoperative pain and the pain of labor. Prolonged use may lead to dependence of the morphine type; withdrawal symptoms appear more rapidly than with morphine and are of shorter duration. [MeSH]

Compound Research Comparison

Studies
(1-methyl-4-piperidyl 4'-fluorobenzoate)
Trials
(1-methyl-4-piperidyl 4'-fluorobenzoate)
Recent Studies (post-2010)
(1-methyl-4-piperidyl 4'-fluorobenzoate)
Studies
(meperidine)
Trials
(meperidine)
Recent Studies (post-2010) (meperidine)
5015,7481,228343

Protein Interaction Comparison

ProteinTaxonomy1-methyl-4-piperidyl 4'-fluorobenzoate (IC50)meperidine (IC50)
Delta-type opioid receptorMus musculus (house mouse)0.5
Kappa-type opioid receptorMus musculus (house mouse)0.5
Mu-type opioid receptorHomo sapiens (human)0.4075
Delta-type opioid receptorHomo sapiens (human)0.5
Kappa-type opioid receptorHomo sapiens (human)1.435
Mu-type opioid receptorMus musculus (house mouse)0.5
Mu-type opioid receptorCavia porcellus (domestic guinea pig)0.5
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)0.3236

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19901 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Brochmann-Hanssen, E; Cheng, CY; Waters, JA1

Other Studies

1 other study(ies) available for 1-methyl-4-piperidyl 4'-fluorobenzoate and meperidine

ArticleYear
Quantitative structure-activity relationships of aromatic esters of 1-methyl-4-piperidinol as analgesics.
    Journal of medicinal chemistry, 1982, Volume: 25, Issue:2

    Topics: Analgesics; Animals; Chemical Phenomena; Chemistry, Physical; Hydrogen Bonding; Meperidine; Mice; Molecular Conformation; Morphine; Piperidines; Reaction Time; Structure-Activity Relationship

1982