ATP diphosphatase activity

Definition

Target type: molecularfunction

Catalysis of the reaction: ATP + H2O = AMP + H+ + diphosphate. [RHEA:14245]

ATP diphosphatase activity is a critical enzymatic process that hydrolyzes adenosine triphosphate (ATP) into adenosine diphosphate (ADP) and inorganic phosphate (Pi). This reaction is essential for various cellular functions, including energy production, signal transduction, and cellular transport.

ATP diphosphatases, also known as ATPases, act as molecular motors that utilize the energy released from ATP hydrolysis to drive cellular processes. They function by binding ATP and then catalyzing its breakdown, releasing energy that can be used to power other reactions or mechanical work.

Specifically, ATP diphosphatases play a key role in the following processes:

- **Energy production:** The hydrolysis of ATP by ATP diphosphatases provides the energy required for cellular processes such as muscle contraction, protein synthesis, and active transport.
- **Signal transduction:** ATP diphosphatases are involved in signal transduction pathways by hydrolyzing ATP to generate ADP, which can act as a signaling molecule.
- **Cellular transport:** ATP diphosphatases power active transport systems that move molecules across cell membranes against their concentration gradient, ensuring the proper distribution of nutrients, ions, and waste products.

ATP diphosphatases are diverse in their structure and function, with different isoforms exhibiting specific roles in various cellular compartments. Their activity is regulated by factors such as substrate concentration, pH, and the presence of specific ions or cofactors.

Overall, ATP diphosphatase activity is a fundamental enzymatic process that underpins a wide range of cellular functions, making it crucial for maintaining cell viability and organismal survival.'
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Proteins (2)

Compounds (27)