| Protein | Synonyms | Taxonomy |
|---|
| Protein disulfide-isomerase A4 | EC 5.3.4.1; Endoplasmic reticulum resident protein 70; ER protein 70; ERp70; Endoplasmic reticulum resident protein 72; ER protein 72; ERp-72; ERp72 | Homo sapiens (human) |
| Cytochrome P450 3A4 | EC 1.14.14.1; 1,4-cineole 2-exo-monooxygenase; 1,8-cineole 2-exo-monooxygenase; 1.14.14.56; Albendazole monooxygenase (sulfoxide-forming); 1.14.14.73; Albendazole sulfoxidase; CYPIIIA3; CYPIIIA4; Cholesterol 25-hydroxylase; Cytochrome P450 3A3; Cytochrome | Homo sapiens (human) |
| Cytochrome P450 2B6 | EC 1.14.13.-; 1,4-cineole 2-exo-monooxygenase; CYPIIB6; Cytochrome P450 IIB1 | Homo sapiens (human) |
| Cytochrome P450 3A5 | EC 1.14.14.1; CYPIIIA5; Cytochrome P450-PCN3 | Homo sapiens (human) |
| Patatin-like phospholipase domain-containing protein 4 | EC 3.1.1.3; Protein GS2 | Homo sapiens (human) |
| Protein disulfide-isomerase A2 | EC 5.3.4.1; Pancreas-specific protein disulfide isomerase; PDIp | Homo sapiens (human) |
| Retinoid isomerohydrolase | EC 3.1.1.64; All-trans-retinyl-palmitate hydrolase; Lutein isomerase; Meso-zeaxanthin isomerase; 5.3.3.22; Retinal pigment epithelium-specific 65 kDa protein; Retinol isomerase | Homo sapiens (human) |
| Cytochrome P450 2A13 | EC 1.14.14.1; CYPIIA13 | Homo sapiens (human) |
| Dehydrogenase/reductase SDR family member 9 | EC 1.1.1.209; EC 1.1.1.53; 3-alpha hydroxysteroid dehydrogenase; 3-alpha-HSD; NADP-dependent retinol dehydrogenase/reductase; RDH-E2; RDHL; Retinol dehydrogenase 15; 1.1.1.105; Short chain dehydrogenase/reductase family 9C member 4; Short-chain dehydrogen | Homo sapiens (human) |
| Diacylglycerol O-acyltransferase 1 | EC 2.3.1.20; ACAT-related gene product 1; Acyl-CoA retinol O-fatty-acyltransferase; ARAT; Retinol O-fatty-acyltransferase; 2.3.1.76; Diglyceride acyltransferase | Homo sapiens (human) |
| Cytochrome P450 2A6 | EC 1.14.13.-; 1,4-cineole 2-exo-monooxygenase; CYPIIA6; Coumarin 7-hydroxylase; Cytochrome P450 IIA3; Cytochrome P450(I) | Homo sapiens (human) |
| Cytochrome P450 3A7 | EC 1.14.14.1; CYPIIIA7; Cytochrome P450-HFLA; P450HLp2 | Homo sapiens (human) |
| Cytochrome P450 2A7 | EC 1.14.14.1; CYPIIA7; Cytochrome P450 IIA4 | Homo sapiens (human) |
| Retinal dehydrogenase 1 | RALDH 1; RalDH1; EC 1.2.1.-; EC 1.2.1.36; ALDH-E1; ALHDII; Aldehyde dehydrogenase family 1 member A1; Aldehyde dehydrogenase, cytosolic | Homo sapiens (human) |
| Peptidyl-prolyl cis-trans isomerase B | PPIase B; EC 5.2.1.8; CYP-S1; Cyclophilin B; Rotamase B; S-cyclophilin; SCYLP | Homo sapiens (human) |
| Cytochrome P450 3A43 | EC 1.14.14.1 | Homo sapiens (human) |
| Dehydrogenase/reductase SDR family member 4 | EC 1.1.1.184; NADPH-dependent carbonyl reductase/NADP-retinol dehydrogenase; CR; PHCR; NADPH-dependent retinol dehydrogenase/reductase; NRDR; humNRDR; Peroxisomal short-chain alcohol dehydrogenase; PSCD; SCAD-SRL; Short chain dehydrogenase/reductase famil | Homo sapiens (human) |
| Endoplasmic reticulum chaperone BiP | EC 3.6.4.10; 78 kDa glucose-regulated protein; GRP-78; Binding-immunoglobulin protein; BiP; Heat shock protein 70 family protein 5; HSP70 family protein 5; Heat shock protein family A member 5; Immunoglobulin heavy chain-binding protein | Homo sapiens (human) |
| Cytochrome P450 26A1 | EC 1.14.13.-; Cytochrome P450 retinoic acid-inactivating 1; Cytochrome P450RAI; hP450RAI; Retinoic acid 4-hydroxylase; Retinoic acid-metabolizing cytochrome | Homo sapiens (human) |
| UDP-glucuronosyltransferase 1A1 | UGT1A1; EC 2.4.1.17; Bilirubin-specific UDPGT isozyme 1; hUG-BR1; UDP-glucuronosyltransferase 1-1; UDPGT 1-1; UGT1*1; UGT1-01; UGT1.1; UDP-glucuronosyltransferase 1A isoform 1 | Homo sapiens (human) |
| Protein disulfide-isomerase A6 | EC 5.3.4.1; Endoplasmic reticulum protein 5; ER protein 5; ERp5; Protein disulfide isomerase P5; Thioredoxin domain-containing protein 7 | Homo sapiens (human) |
| Acyl-CoA wax alcohol acyltransferase 1 | EC 2.3.1.75; Diacylglycerol O-acyltransferase 2-like protein 3; Diacylglycerol acyltransferase 2; Long-chain-alcohol O-fatty-acyltransferase 1 | Homo sapiens (human) |
| Alcohol dehydrogenase 1A | EC 1.1.1.1; Alcohol dehydrogenase subunit alpha | Homo sapiens (human) |
| Lecithin retinol acyltransferase | EC 2.3.1.135; Phosphatidylcholine--retinol O-acyltransferase | Homo sapiens (human) |
| All-trans-retinol 13,14-reductase | EC 1.3.99.23; All-trans-13,14-dihydroretinol saturase; RetSat; PPAR-alpha-regulated and starvation-induced gene protein | Homo sapiens (human) |
| Retinal dehydrogenase 2 | RALDH 2; RalDH2; EC 1.2.1.36; Aldehyde dehydrogenase family 1 member A2; Retinaldehyde-specific dehydrogenase type 2; RALDH(II) | Homo sapiens (human) |
| Retinol dehydrogenase 16 | EC 1.1.1.105; EC 1.1.1.209; EC 1.1.1.315; EC 1.1.1.53; Human epidermal retinol dehydrogenase; hRDH-E; Microsomal NAD(+)-dependent retinol dehydrogenase 4; RoDH-4; Short chain dehydrogenase/reductase family 9C member 8; Sterol/retinol dehydrogenase | Homo sapiens (human) |
| Endoplasmic reticulum resident protein 29 | ERp29; Endoplasmic reticulum resident protein 28; ERp28; Endoplasmic reticulum resident protein 31; ERp31 | Homo sapiens (human) |
| Beta,beta-carotene 15,15'-dioxygenase | EC 1.13.11.63; Beta-carotene dioxygenase 1; Beta-carotene oxygenase 1 | Homo sapiens (human) |
| Short-chain dehydrogenase/reductase 3 | EC 1.1.1.300; DD83.1; Retinal short-chain dehydrogenase/reductase 1; retSDR1; Retinol dehydrogenase 17; Short chain dehydrogenase/reductase family 16C member 1 | Homo sapiens (human) |
| Retinol dehydrogenase 11 | EC 1.1.1.300; Androgen-regulated short-chain dehydrogenase/reductase 1; HCV core-binding protein HCBP12; Prostate short-chain dehydrogenase/reductase 1; Retinal reductase 1; RalR1; Short chain dehydrogenase/reductase family 7C member 1 | Homo sapiens (human) |
| Retinol dehydrogenase 12 | EC 1.1.1.300; All-trans and 9-cis retinol dehydrogenase; Short chain dehydrogenase/reductase family 7C member 2 | Homo sapiens (human) |
| Stromal cell-derived factor 2-like protein 1 | SDF2-like protein 1; PWP1-interacting protein 8 | Homo sapiens (human) |
| Retinol dehydrogenase 8 | EC 1.1.1.300; Photoreceptor outer segment all-trans retinol dehydrogenase; Short chain dehydrogenase/reductase family 28C member 2 | Homo sapiens (human) |
| DnaJ homolog subfamily B member 11 | APOBEC1-binding protein 2; ABBP-2; DnaJ protein homolog 9; ER-associated DNAJ; ER-associated Hsp40 co-chaperone; Endoplasmic reticulum DNA J domain-containing protein 3; ER-resident protein ERdj3; ERdj3; ERj3p; HEDJ; Human DnaJ protein 9; hDj-9; PWP1-inte | Homo sapiens (human) |
| HYOU1 protein | | Homo sapiens (human) |
| Endoplasmin | | Homo sapiens (human) |
| Compound | Description |
|---|
| NADH | |
| tretinoin | An important regulator of GENE EXPRESSION during growth and development, and in NEOPLASMS. Tretinoin, also known as retinoic acid and derived from maternal VITAMIN A, is essential for normal GROWTH; and EMBRYONIC DEVELOPMENT. An excess of tretinoin can be teratogenic. It is used in the treatment of PSORIASIS; ACNE VULGARIS; and several other SKIN DISEASES. It has also been approved for use in promyelocytic leukemia (LEUKEMIA, PROMYELOCYTIC, ACUTE). |
| retinol | |
| alitretinoin | A retinoid that is used for the treatment of chronic hand ECZEMA unresponsive to topical CORTICOSTEROIDS. It is also used to treat cutaneous lesions associated with AIDS-related KAPOSI SARCOMA. |
| beta carotene | A carotenoid that is a precursor of VITAMIN A. Beta carotene is administered to reduce the severity of photosensitivity reactions in patients with erythropoietic protoporphyria (PORPHYRIA, ERYTHROPOIETIC). |
| retinol palmitate | RN given refers to parent cpd; structure |
| retinaldehyde | A diterpene derived from the carotenoid VITAMIN A which functions as the active component of the visual cycle. It is the prosthetic group of RHODOPSIN (i.e., covalently bonded to ROD OPSIN as 11-cis-retinal). When stimulated by visible light, rhodopsin transforms this cis-isomer of retinal to the trans-isomer (11-trans-retinal). This transformation straightens-out the bend of the retinal molecule and causes a change in the shape of rhodopsin triggering the visual process. A series of energy-requiring enzyme-catalyzed reactions convert the 11-trans-retinal back to the cis-isomer. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| Coenzyme A | |
| 13,14-dihydroretinol | |
| 11-cis-Retinol | |
| 11-cis-retinal | |
| retinoyl beta-glucuronide | |
| 4-oxoretinol | |
| 5,6-epoxyretinoic acid | RN given refers to parent cpd without isomeric designation |
| NAD | A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed) |
| 9-cis-retinal | |
| 4-oxoretinoic acid | RN given refers to cpd without isomeric designation; structure |
| 4-hydroxyretinoic acid | RN given refers to cpd without isomeric designation; structure |
| acetyl coenzyme a | Acetyl CoA participates in the biosynthesis of fatty acids and sterols, in the oxidation of fatty acids and in the metabolism of many amino acids. It also acts as a biological acetylating agent. |
| creolin | from refined coal tar oils |
| Phosphatidylcholines | Derivatives of PHOSPHATIDIC ACIDS in which the phosphoric acid is bound in ester linkage to a CHOLINE moiety. |