| Protein | Synonyms | Taxonomy |
|---|
| Nucleoprotein | N; Nucleocapsid protein; NC; Protein N | Severe acute respiratory syndrome coronavirus 2 |
| Neutrophil cytosol factor 1 | NCF-1; 47 kDa autosomal chronic granulomatous disease protein; 47 kDa neutrophil oxidase factor; NCF-47K; Neutrophil NADPH oxidase factor 1; Nox organizer 2; Nox-organizing protein 2; SH3 and PX domain-containing protein 1A; p47-phox | Homo sapiens (human) |
| Target of rapamycin complex 2 subunit MAPKAP1 | TORC2 subunit MAPKAP1; Mitogen-activated protein kinase 2-associated protein 1; Stress-activated map kinase-interacting protein 1; SAPK-interacting protein 1; mSIN1 | Homo sapiens (human) |
| 3-phosphoinositide-dependent protein kinase 1 | hPDK1; EC 2.7.11.1 | Homo sapiens (human) |
| Integrin beta-3 | Platelet membrane glycoprotein IIIa; GPIIIa | Homo sapiens (human) |
| Tyrosine-protein kinase Fyn | EC 2.7.10.2; Proto-oncogene Syn; Proto-oncogene c-Fyn; Src-like kinase; SLK; p59-Fyn | Homo sapiens (human) |
| Heat shock protein HSP 90-alpha | EC 3.6.4.10; Heat shock 86 kDa; HSP 86; HSP86; Lipopolysaccharide-associated protein 2; LAP-2; LPS-associated protein 2; Renal carcinoma antigen NY-REN-38 | Homo sapiens (human) |
| Tyrosine-protein kinase receptor UFO | EC 2.7.10.1; AXL oncogene | Homo sapiens (human) |
| RAC-alpha serine/threonine-protein kinase | EC 2.7.11.1; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; Proto-oncogene c-Akt; RAC-PK-alpha | Homo sapiens (human) |
| Vascular endothelial growth factor receptor 2 | VEGFR-2; EC 2.7.10.1; Fetal liver kinase 1; FLK-1; Kinase insert domain receptor; KDR; Protein-tyrosine kinase receptor flk-1 | Homo sapiens (human) |
| Focal adhesion kinase 1 | FADK 1; EC 2.7.10.2; Focal adhesion kinase-related nonkinase; FRNK; Protein phosphatase 1 regulatory subunit 71; PPP1R71; Protein-tyrosine kinase 2; p125FAK; pp125FAK | Homo sapiens (human) |
| Serine/threonine-protein kinase PAK 1 | EC 2.7.11.1; Alpha-PAK; p21-activated kinase 1; PAK-1; p65-PAK | Homo sapiens (human) |
| Protein-tyrosine kinase 2-beta | EC 2.7.10.2; Calcium-dependent tyrosine kinase; CADTK; Calcium-regulated non-receptor proline-rich tyrosine kinase; Cell adhesion kinase beta; CAK-beta; CAKB; Focal adhesion kinase 2; FADK 2; Proline-rich tyrosine kinase 2; Related adhesion focal tyrosine | Homo sapiens (human) |
| Sphingosine kinase 1 | SK 1; SPK 1; EC 2.7.1.91; Acetyltransferase SPHK1; 2.3.1.- | Homo sapiens (human) |
| Dedicator of cytokinesis protein 1 | 180 kDa protein downstream of CRK; DOCK180 | Homo sapiens (human) |
| SH2 domain-containing adapter protein B | | Homo sapiens (human) |
| Paxillin | | Homo sapiens (human) |
| 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 | EC 3.1.4.11; PLC-148; Phosphoinositide phospholipase C-gamma-1; Phospholipase C-II; PLC-II; Phospholipase C-gamma-1; PLC-gamma-1 | Homo sapiens (human) |
| Serine/threonine-protein kinase PAK 3 | EC 2.7.11.1; Beta-PAK; Oligophrenin-3; p21-activated kinase 3; PAK-3 | Homo sapiens (human) |
| Integrin alpha-V | Vitronectin receptor; Vitronectin receptor subunit alpha | Homo sapiens (human) |
| Vascular endothelial growth factor receptor 1 | VEGFR-1; EC 2.7.10.1; Fms-like tyrosine kinase 1; FLT-1; Tyrosine-protein kinase FRT; Tyrosine-protein kinase receptor FLT; FLT; Vascular permeability factor receptor | Homo sapiens (human) |
| Vascular endothelial growth factor receptor 3 | VEGFR-3; EC 2.7.10.1; Fms-like tyrosine kinase 4; FLT-4; Tyrosine-protein kinase receptor FLT4 | Homo sapiens (human) |
| Serine/threonine-protein kinase mTOR | EC 2.7.11.1; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; Mammalian target of rapamycin; mTOR; Mechanistic target of rapamycin; Rapamycin and FKBP12 target 1; Rapamycin target protein 1 | Homo sapiens (human) |
| Cell division control protein 42 homolog | EC 3.6.5.2; G25K GTP-binding protein | Homo sapiens (human) |
| Catenin alpha-1 | Alpha E-catenin; Cadherin-associated protein; Renal carcinoma antigen NY-REN-13 | Homo sapiens (human) |
| Caveolin-1 | | Homo sapiens (human) |
| S-adenosylhomocysteine hydrolase-like protein 1 | DC-expressed AHCY-like molecule; IP(3)Rs binding protein released with IP(3); IRBIT; Putative adenosylhomocysteinase 2; S-adenosyl-L-homocysteine hydrolase 2; AdoHcyase 2 | Homo sapiens (human) |
| Neuropilin-1 | Vascular endothelial cell growth factor 165 receptor | Homo sapiens (human) |
| Vascular endothelial growth factor A | VEGF-A; Vascular permeability factor; VPF | Homo sapiens (human) |
| Adapter molecule crk | Proto-oncogene c-Crk; p38 | Homo sapiens (human) |
| Placenta growth factor | PlGF | Homo sapiens (human) |
| Ras-related C3 botulinum toxin substrate 1 | EC 3.6.5.2; Cell migration-inducing gene 5 protein; Ras-like protein TC25; p21-Rac1 | Homo sapiens (human) |
| SH2 domain-containing protein 2A | SH2 domain-containing adapter protein; T cell-specific adapter protein; TSAd; VEGF receptor-associated protein | Homo sapiens (human) |
| Heat shock protein beta-1 | HspB1; 28 kDa heat shock protein; Estrogen-regulated 24 kDa protein; Heat shock 27 kDa protein; HSP 27; Stress-responsive protein 27; SRP27 | Homo sapiens (human) |
| Cytochrome b-245 heavy chain | EC 1.-.-.-; CGD91-phox; Cytochrome b(558) subunit beta; Cytochrome b558 subunit beta; Heme-binding membrane glycoprotein gp91phox; NADPH oxidase 2; Neutrophil cytochrome b 91 kDa polypeptide; Superoxide-generating NADPH oxidase heavy chain subunit; gp91-1 | Homo sapiens (human) |
| Calmodulin-1 | | Homo sapiens (human) |
| Nitric oxide synthase, endothelial | EC 1.14.13.39; Constitutive NOS; cNOS; EC-NOS; Endothelial NOS; eNOS; NOS type III; NOSIII | Homo sapiens (human) |
| Transforming protein RhoA | EC 3.6.5.2; Rho cDNA clone 12; h12 | Homo sapiens (human) |
| Serine/threonine-protein kinase PAK 2 | EC 2.7.11.1; Gamma-PAK; PAK65; S6/H4 kinase; p21-activated kinase 2; PAK-2; p58 | Homo sapiens (human) |
| Rapamycin-insensitive companion of mTOR | AVO3 homolog; hAVO3 | Homo sapiens (human) |
| Target of rapamycin complex subunit LST8 | TORC subunit LST8; G protein beta subunit-like; Gable; Protein GbetaL; Mammalian lethal with SEC13 protein 8; mLST8 | Homo sapiens (human) |
| SHC-transforming protein 2 | Protein Sck; SHC-transforming protein B; Src homology 2 domain-containing-transforming protein C2; SH2 domain protein C2 | Homo sapiens (human) |
| Vascular endothelial growth factor D | VEGF-D; c-Fos-induced growth factor; FIGF | Homo sapiens (human) |
| Vascular endothelial growth factor B | VEGF-B; VEGF-related factor; VRF | Homo sapiens (human) |
| Vascular endothelial growth factor C | VEGF-C; Flt4 ligand; Flt4-L; Vascular endothelial growth factor-related protein; VRP | Homo sapiens (human) |
| Membrane protein | M; E1 glycoprotein; Matrix glycoprotein; Membrane glycoprotein | Severe acute respiratory syndrome coronavirus 2 |
| Neuropilin-2 | Vascular endothelial cell growth factor 165 receptor 2 | Homo sapiens (human) |
| Protein BRICK1 | BRK1 | Homo sapiens (human) |
| Catenin delta-1 | Cadherin-associated Src substrate; CAS; p120 catenin; p120(ctn); p120(cas) | Homo sapiens (human) |
| Breast cancer anti-estrogen resistance protein 1 | CRK-associated substrate; Cas scaffolding protein family member 1; p130cas | Homo sapiens (human) |
| Ras GTPase-activating protein 1 | GAP; GTPase-activating protein; RasGAP; Ras p21 protein activator; p120GAP | Homo sapiens (human) |
| Cytochrome b-245 light chain | Cytochrome b(558) alpha chain; Cytochrome b558 subunit alpha; Neutrophil cytochrome b 22 kDa polypeptide; Superoxide-generating NADPH oxidase light chain subunit; p22 phagocyte B-cytochrome; p22-phox; p22phox | Homo sapiens (human) |
| Neutrophil cytosol factor 2 | NCF-2; 67 kDa neutrophil oxidase factor; NADPH oxidase activator 2; Neutrophil NADPH oxidase factor 2; p67-phox | Homo sapiens (human) |
| Cadherin-5 | 7B4 antigen; Vascular endothelial cadherin; VE-cadherin | Homo sapiens (human) |
| Nck-associated protein 1-like | Hematopoietic protein 1; Membrane-associated protein HEM-1 | Homo sapiens (human) |
| Proline-rich protein 5 | Protein observed with Rictor-1; Protor-1 | Homo sapiens (human) |
| Angio-associated migratory cell protein | | Homo sapiens (human) |
| Neutrophil cytosol factor 4 | NCF-4; Neutrophil NADPH oxidase factor 4; SH3 and PX domain-containing protein 4; p40-phox; p40phox | Homo sapiens (human) |
| Brain-specific angiogenesis inhibitor 1-associated protein 2 | BAI-associated protein 2; BAI1-associated protein 2; Protein BAP2; Fas ligand-associated factor 3; FLAF3; Insulin receptor substrate p53/p58; IRS-58; IRSp53/58; Insulin receptor substrate protein of 53 kDa; IRSp53; Insulin receptor substrate p53 | Homo sapiens (human) |
| Nck-associated protein 1 | NAP 1; Membrane-associated protein HEM-2; p125Nap1 | Homo sapiens (human) |
| Compound | Description |
|---|
| hydronium ion | |
| Nitric Oxide | A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP. |
| Arginine | An essential amino acid that is physiologically active in the L-form. |
| Calcium | A basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes. |
| Zinc | A metallic element of atomic number 30 and atomic weight 65.38. It is a necessary trace element in the diet, forming an essential part of many enzymes, and playing an important role in protein synthesis and in cell division. Zinc deficiency is associated with ANEMIA, short stature, HYPOGONADISM, impaired WOUND HEALING, and geophagia. It is known by the symbol Zn. |
| Flavin Mononucleotide | A coenzyme for a number of oxidative enzymes including NADH DEHYDROGENASE. It is the principal form in which RIBOFLAVIN is found in cells and tissues. |
| Superoxides | Highly reactive compounds produced when oxygen is reduced by a single electron. In biological systems, they may be generated during the normal catalytic function of a number of enzymes and during the oxidation of hemoglobin to METHEMOGLOBIN. In living organisms, SUPEROXIDE DISMUTASE protects the cell from the deleterious effects of superoxides. |
| adenosine diphosphate | Adenosine 5'-(trihydrogen diphosphate). An adenine nucleotide containing two phosphate groups esterified to the sugar moiety at the 5'-position. |
| Magnesium | A metallic element that has the atomic symbol Mg, atomic number 12, and atomic weight 24.31. It is important for the activity of many enzymes, especially those involved in OXIDATIVE PHOSPHORYLATION. |
| Water | A clear, odorless, tasteless liquid that is essential for most animal and plant life and is an excellent solvent for many substances. The chemical formula is hydrogen oxide (H2O). (McGraw-Hill Dictionary of Scientific and Technical Terms, 4th ed) |
| Oxygen | An element with atomic symbol O, atomic number 8, and atomic weight [15.99903; 15.99977]. It is the most abundant element on earth and essential for respiration. |
| guanosine diphosphate | A guanine nucleotide containing two phosphate groups esterified to the sugar moiety. |
| Guanosine Monophosphate | A guanine nucleotide containing one phosphate group esterified to the sugar moiety and found widely in nature. |
| Guanosine Diphosphate | A guanine nucleotide containing two phosphate groups esterified to the sugar moiety. |
| sapropterin | RN given refers to parent cpd; co-factor required for catalytic activity of nitric oxide synthases |
| nad | A coenzyme composed of ribosylnicotinamide 5'-diphosphate coupled to adenosine 5'-phosphate by pyrophosphate linkage. It is found widely in nature and is involved in numerous enzymatic reactions in which it serves as an electron carrier by being alternately oxidized (NAD+) and reduced (NADH). (Dorland, 27th ed) |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| NADP | Nicotinamide adenine dinucleotide phosphate. A coenzyme composed of ribosylnicotinamide 5'-phosphate (NMN) coupled by pyrophosphate linkage to the 5'-phosphate adenosine 2',5'-bisphosphate. It serves as an electron carrier in a number of reactions, being alternately oxidized (NADP+) and reduced (NADPH). (Dorland, 27th ed) |
| adenosine triphosphate | An adenine nucleotide containing three phosphate groups esterified to the sugar moiety. In addition to its crucial roles in metabolism adenosine triphosphate is a neurotransmitter. |
| sphingosine 1-phosphate | RN given refers to (R-(R*,S*-(E)))-isomer; RN for cpd without isomeric designation not available 8/89 |
| Flavin-Adenine Dinucleotide | A condensation product of riboflavin and adenosine diphosphate. The coenzyme of various aerobic dehydrogenases, e.g., D-amino acid oxidase and L-amino acid oxidase. (Lehninger, Principles of Biochemistry, 1982, p972) |
| heme | The color-furnishing portion of hemoglobin. It is found free in tissues and as the prosthetic group in many hemeproteins. |