Page last updated: 2024-09-04

telbivudine and saquinavir

telbivudine has been researched along with saquinavir in 4 studies

Compound Research Comparison

Studies
(telbivudine)
Trials
(telbivudine)
Recent Studies (post-2010)
(telbivudine)
Studies
(saquinavir)
Trials
(saquinavir)
Recent Studies (post-2010) (saquinavir)
486853321,454256219

Protein Interaction Comparison

ProteinTaxonomytelbivudine (IC50)saquinavir (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)1.9
Bile salt export pumpHomo sapiens (human)3.9
Gag-Pol polyproteinHuman immunodeficiency virus type 1 (BRU ISOLATE)0.016
Gag-Pol polyproteinHuman immunodeficiency virus type 2 (ISOLATE ROD)0.0084
Gag polyproteinHIV-1 M:B_MN0.0131
ATP-dependent translocase ABCB1Homo sapiens (human)4.05
Cytochrome P450 3A4Homo sapiens (human)1.5
Gag-Pol polyproteinHuman immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)0.0066
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)4.273
Substance-K receptorHomo sapiens (human)6.214
Thromboxane-A synthase Homo sapiens (human)2.182
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)4.273
Mu-type opioid receptorHomo sapiens (human)9.625
Kappa-type opioid receptorHomo sapiens (human)6.951
Exoribonuclease H Human immunodeficiency virus 20.0005
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)1.9
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)1.9
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)1.9
Genome polyprotein Human rhinovirus sp.0.0005
Solute carrier family 22 member 1Rattus norvegicus (Norway rat)8.26
Protease Human immunodeficiency virus 10.0217
Protease Human immunodeficiency virus 10.0004

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Brown, AM; Bruening-Wright, A; Kramer, J; Kuryshev, YA; Myatt, G; Obejero-Paz, CA; Verducci, JS1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1

Reviews

1 review(s) available for telbivudine and saquinavir

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

3 other study(ies) available for telbivudine and saquinavir

ArticleYear
MICE models: superior to the HERG model in predicting Torsade de Pointes.
    Scientific reports, 2013, Volume: 3

    Topics: ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Theoretical; Patch-Clamp Techniques; Predictive Value of Tests; Torsades de Pointes

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
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