Page last updated: 2024-09-02

st 587 and nifedipine

st 587 has been researched along with nifedipine in 7 studies

Compound Research Comparison

Studies
(st 587)
Trials
(st 587)
Recent Studies (post-2010)
(st 587)
Studies
(nifedipine)
Trials
(nifedipine)
Recent Studies (post-2010) (nifedipine)
670016,0242,4961,505

Protein Interaction Comparison

ProteinTaxonomyst 587 (IC50)nifedipine (IC50)
perilipin-5Homo sapiens (human)7.133
perilipin-1Homo sapiens (human)9.619
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform aHomo sapiens (human)8.376
Voltage-dependent L-type calcium channel subunit alpha-1CCavia porcellus (domestic guinea pig)0.0429
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)0.035
Cytochrome P450 1A2Homo sapiens (human)0.3
Cytochrome P450 3A4Homo sapiens (human)10
Adenosine receptor A3Homo sapiens (human)7.214
Cytochrome P450 2C9 Homo sapiens (human)3.06
5-hydroxytryptamine receptor 2ARattus norvegicus (Norway rat)10
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)7.214
Voltage-dependent L-type calcium channel subunit alpha-1CRattus norvegicus (Norway rat)0.0385
Potassium voltage-gated channel subfamily A member 5Homo sapiens (human)6.1
3-oxo-5-alpha-steroid 4-dehydrogenase 1 Rattus norvegicus (Norway rat)1.12
Adenosine receptor A1Homo sapiens (human)7.701
3-oxo-5-alpha-steroid 4-dehydrogenase 2Rattus norvegicus (Norway rat)1.12
C-C chemokine receptor type 2Homo sapiens (human)2.191
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)7.214
Cytochrome P450 2J2Homo sapiens (human)3.06
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)0.4733
Voltage-dependent L-type calcium channel subunit alpha-1CMus musculus (house mouse)1.2
Voltage-dependent L-type calcium channel subunit alpha-1SMus musculus (house mouse)1.2
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)0.035
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)0.0394
Myosin light chain kinase, smooth muscleHomo sapiens (human)2.02
Potassium channel subfamily K member 2 Bos taurus (cattle)8.2
Indoleamine 2,3-dioxygenase 2Mus musculus (house mouse)1.5
Voltage-dependent L-type calcium channel subunit alpha-1DMus musculus (house mouse)1.2
Voltage-dependent L-type calcium channel subunit alpha-1FMus musculus (house mouse)1.2

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19903 (42.86)18.7374
1990's4 (57.14)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tabrizchi, R; Triggle, CR2
Faber, JE; McGillivray-Anderson, KM1
de Jonge, A; Thoolen, MJ; Timmermans, PB; van Zwieten, PA; Wilffert, B1
de Jonge, A; Mathy, MJ; Thoolen, MJ; Timmermans, PB; van Zwieten, PA; Wilffert, B1
de Jonge, A; Kalkman, HO; Mathy, MJ; Thoolen, MJ; Timmermans, PB; van Meel, JC; van Zwieten, PA; Wilffert, B1
Beenen, OH; Mathy, MJ; Pfaffendorf, M; van Zwieten, PA1

Other Studies

7 other study(ies) available for st 587 and nifedipine

ArticleYear
The interrelationship between the effects of captopril and nifedipine on pressor responses elicited by selective alpha-adrenoceptor agonists in the pithed rat preparation.
    Journal of cardiovascular pharmacology, 1992, Volume: 19, Issue:4

    Topics: Adrenergic alpha-Agonists; Animals; Azepines; Blood Pressure; Captopril; Clonidine; Decerebrate State; Imidazoles; Male; Nifedipine; Rats; Rats, Inbred Strains

1992
Effect of reduced blood flow on alpha 1- and alpha 2-adrenoceptor constriction of rat skeletal muscle microvessels.
    Circulation research, 1991, Volume: 69, Issue:1

    Topics: Acidosis; Animals; Clonidine; Male; Microcirculation; Muscles; Nifedipine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Regional Blood Flow; Vasoconstriction

1991
Effects of staurosporine on the pressor responses to alpha-adrenoceptor agonists in pithed rats: a comparison with nifedipine.
    Pharmacology, 1991, Volume: 43, Issue:3

    Topics: Adrenergic alpha-Agonists; Alkaloids; Animals; Azepines; Blood Pressure; Clonidine; Decerebrate State; Imidazoles; Male; Muscle, Smooth, Vascular; Nifedipine; Protein Kinase C; Rats; Rats, Inbred Strains; Staurosporine

1991
Calcium dependency of vasoconstriction mediated by alpha 1- and alpha 2-adrenoceptors.
    Journal of cardiovascular pharmacology, 1985, Volume: 7 Suppl 6

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Azepines; Blood Pressure; Calcium; Calcium Channel Blockers; Clonidine; Imidazoles; Ion Channels; Nifedipine; Rats; Receptors, Adrenergic, alpha; Regional Blood Flow; Structure-Activity Relationship; Vasoconstriction

1985
Effects of the irreversible alpha-adrenoceptor antagonists phenoxybenzamine and benextramine on the effectiveness of nifedipine in inhibiting alpha 1- and alpha 2-adrenoceptor mediated vasoconstriction in pithed rats.
    Naunyn-Schmiedeberg's archives of pharmacology, 1985, Volume: 329, Issue:4

    Topics: Animals; Azepines; Clonidine; Cystamine; Decerebrate State; Diastole; Dose-Response Relationship, Drug; Imidazoles; Male; Nifedipine; Phenoxybenzamine; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vasoconstriction

1985
Differential effect of calcium entry blockers on alpha 1-adrenoceptor-mediated vasoconstriction in vivo.
    Naunyn-Schmiedeberg's archives of pharmacology, 1983, Volume: 324, Issue:4

    Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Calcium Channel Blockers; Catecholamines; Clonidine; Ethanolamines; Imidazoles; Imidazolines; Male; Methoxamine; Nifedipine; Phenylephrine; Rats; Rats, Inbred Strains; Vasoconstriction; Verapamil

1983
Influence of nifedipine on pressor responses induced by different alpha-adrenoceptor agonists and angiotensin II in pithed diabetic hypertensive rats.
    Journal of hypertension, 1996, Volume: 14, Issue:7

    Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Blood Pressure; Brimonidine Tartrate; Calcium; Calcium Channel Blockers; Clonidine; Diabetes Mellitus, Experimental; Hypertension; Imidazoles; Nifedipine; Quinoxalines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Streptozocin

1996