Page last updated: 2024-09-02

sr 95531 and nicotine

sr 95531 has been researched along with nicotine in 7 studies

Compound Research Comparison

Studies
(sr 95531)
Trials
(sr 95531)
Recent Studies (post-2010)
(sr 95531)
Studies
(nicotine)
Trials
(nicotine)
Recent Studies (post-2010) (nicotine)
610020928,5192,2809,302

Protein Interaction Comparison

ProteinTaxonomysr 95531 (IC50)nicotine (IC50)
Neuronal acetylcholine receptor subunit alpha-4Mus musculus (house mouse)0.0055
Acetylcholine receptor subunit alphaTetronarce californica (Pacific electric ray)0.0025
Acetylcholine receptor subunit betaTetronarce californica (Pacific electric ray)0.0025
Acetylcholine receptor subunit gammaTetronarce californica (Pacific electric ray)0.0025
Acetylcholine receptor subunit deltaTetronarce californica (Pacific electric ray)0.0025
Neuronal acetylcholine receptor subunit alpha-3Rattus norvegicus (Norway rat)0.005
Neuronal acetylcholine receptor subunit alpha-4Rattus norvegicus (Norway rat)0.0046
Neuronal acetylcholine receptor subunit alpha-2Rattus norvegicus (Norway rat)0.005
Neuronal acetylcholine receptor subunit beta-2Rattus norvegicus (Norway rat)0.0046
Neuronal acetylcholine receptor subunit beta-3Rattus norvegicus (Norway rat)0.005
Neuronal acetylcholine receptor subunit beta-4Rattus norvegicus (Norway rat)0.005
Neuronal acetylcholine receptor subunit beta-2Homo sapiens (human)0.3256
Neuronal acetylcholine receptor subunit alpha-5Rattus norvegicus (Norway rat)0.005
Acetylcholine receptor subunit beta-like 2Drosophila melanogaster (fruit fly)4
Neuronal acetylcholine receptor subunit beta-4Homo sapiens (human)0.43
Neuronal acetylcholine receptor subunit alpha-3Homo sapiens (human)0.1866
Neuronal acetylcholine receptor subunit alpha-7Homo sapiens (human)7.6
Neuronal acetylcholine receptor subunit alpha-6Rattus norvegicus (Norway rat)0.005
Neuronal acetylcholine receptor subunit alpha-9Rattus norvegicus (Norway rat)0.0041
Neuronal acetylcholine receptor subunit alpha-4Homo sapiens (human)0.3456
Neuronal acetylcholine receptor subunit alpha-7Mus musculus (house mouse)0.004
Neuronal acetylcholine receptor subunit beta-3Homo sapiens (human)0.0848
Neuronal acetylcholine receptor subunit alpha-7Rattus norvegicus (Norway rat)0.0087
Neuronal acetylcholine receptor subunit alpha-6Homo sapiens (human)0.0848
Neuronal acetylcholine receptor subunit alpha-5Mus musculus (house mouse)0.004
Liver carboxylesterase B-1Rattus norvegicus (Norway rat)0.045
Neuronal acetylcholine receptor subunit beta-3Mus musculus (house mouse)0.004
Neuronal acetylcholine receptor subunit beta-4Mus musculus (house mouse)0.004
Neuronal acetylcholine receptor subunit alpha-3Mus musculus (house mouse)0.004
Neuronal acetylcholine receptor subunit alpha-2Mus musculus (house mouse)0.004
Neuronal acetylcholine receptor subunit beta-2Mus musculus (house mouse)0.004
Neuronal acetylcholine receptor subunit alpha-10Rattus norvegicus (Norway rat)0.005
Neuronal acetylcholine receptor subunit alpha-6Mus musculus (house mouse)0.004

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (14.29)18.2507
2000's3 (42.86)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Changeux, JP; Léna, C1
Baxi, S; Evans, C; Irnaten, M; Mendelowitz, D; Venkatesan, P; Wang, J; Wang, X1
Cunningham, MO; Jenkins, A; Knöpfel, T; Middleton, SJ; Monyer, H; Racca, C; Schofield, IS; Traub, RD; Whittington, MA1
Chen, H; Morikawa, H; Sullivan, MA1
Dergacheva, O; Jameson, H; Lovett-Barr, MR; Mendelowitz, D; Wang, X1
Berg, DK; Duan, J; Gounko, NV; Liu, Z; Lozada, AF; Massey, KA; Wang, X1
Chu, CP; Jin, H; Qiu, DL; Xu, Q; Zhang, BB; Zhang, KM; Zhao, GY1

Other Studies

7 other study(ies) available for sr 95531 and nicotine

ArticleYear
Role of Ca2+ ions in nicotinic facilitation of GABA release in mouse thalamus.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 1997, Jan-15, Volume: 17, Issue:2

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Aconitine; Action Potentials; Alkaloids; Animals; Arousal; Atropine; Azocines; Bacterial Toxins; Bridged Bicyclo Compounds, Heterocyclic; Calcium; Calcium Channel Blockers; Calcium Channels; Carbachol; Cations, Divalent; Cyanobacteria Toxins; Dihydro-beta-Erythroidine; Dimethylphenylpiperazinium Iodide; GABA Antagonists; gamma-Aminobutyric Acid; Ion Transport; Lobeline; Marine Toxins; Mice; Mice, Inbred C57BL; Mice, Knockout; Microcystins; Neurons, Afferent; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Potassium; Pyridazines; Pyridines; Quinolizines; Receptors, GABA-A; Receptors, Nicotinic; Tetrodotoxin; Thalamic Nuclei

1997
Endogenous acetylcholine and nicotine activation enhances GABAergic and glycinergic inputs to cardiac vagal neurons.
    Journal of neurophysiology, 2003, Volume: 89, Issue:5

    Topics: 2-Amino-5-phosphonovalerate; Acetylcholine; Animals; Cholinesterase Inhibitors; Excitatory Amino Acid Antagonists; Excitatory Postsynaptic Potentials; Fluorescent Dyes; GABA Antagonists; gamma-Aminobutyric Acid; Glycine; Glycine Agents; Heart; Neostigmine; Neurons; Nicotine; Nicotinic Agonists; Parasympathetic Nervous System; Picrotoxin; Pyridazines; Rats; Strychnine; Synaptic Transmission; Vagus Nerve

2003
High-frequency network oscillations in cerebellar cortex.
    Neuron, 2008, Jun-12, Volume: 58, Issue:5

    Topics: Action Potentials; Animals; Carbenoxolone; Cerebellar Cortex; Electroencephalography; GABA Antagonists; In Vitro Techniques; Mice; Mice, Inbred C57BL; Nerve Net; Nicotine; Nicotinic Agonists; Periodicity; Pyramidal Cells; Pyridazines; Sodium Channel Blockers; Tetrodotoxin

2008
Recurrent inhibitory network among striatal cholinergic interneurons.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008, Aug-27, Volume: 28, Issue:35

    Topics: Acetylcholine; Adrenergic Uptake Inhibitors; alpha-Methyltyrosine; Animals; Animals, Newborn; Cholinergic Fibers; Corpus Striatum; Drug Interactions; Enzyme Inhibitors; Excitatory Amino Acid Agents; GABA Antagonists; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Interneurons; Neural Inhibition; Nicotine; Nicotinic Agonists; Nicotinic Antagonists; Patch-Clamp Techniques; Pyridazines; Rats; Rats, Sprague-Dawley; Reserpine

2008
The lateral paragigantocellular nucleus modulates parasympathetic cardiac neurons: a mechanism for rapid eye movement sleep-dependent changes in heart rate.
    Journal of neurophysiology, 2010, Volume: 104, Issue:2

    Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Animals; Animals, Newborn; Biophysics; Electric Stimulation; Excitatory Amino Acid Antagonists; GABA Antagonists; Heart; Heart Rate; In Vitro Techniques; Inhibitory Postsynaptic Potentials; Medulla Oblongata; N-Methylaspartate; Neurons; Nicotine; Nicotinic Agonists; Patch-Clamp Techniques; Pyridazines; Rats; Rats, Sprague-Dawley; Sleep, REM; Time Factors; Vagus Nerve; Valine

2010
Glutamatergic synapse formation is promoted by α7-containing nicotinic acetylcholine receptors.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, May-30, Volume: 32, Issue:22

    Topics: Age Factors; alpha7 Nicotinic Acetylcholine Receptor; Analysis of Variance; Animals; Animals, Newborn; Cells, Cultured; Disks Large Homolog 4 Protein; Electric Stimulation; Embryo, Mammalian; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; Gene Expression Regulation, Developmental; Glutamic Acid; Green Fluorescent Proteins; Guanylate Kinases; Hippocampus; Male; Membrane Proteins; Mice; Mice, Inbred C57BL; Mice, Knockout; Microscopy, Electron, Transmission; Neurites; Neurons; Nicotine; Nicotinic Agonists; Organ Culture Techniques; Patch-Clamp Techniques; Pyridazines; Pyridinium Compounds; Quaternary Ammonium Compounds; Rats; Receptors, AMPA; Receptors, Nicotinic; RNA, Small Interfering; Sodium Channel Blockers; Synapses; Tetrodotoxin; Time Factors; Transduction, Genetic; Vesicular Glutamate Transport Protein 1; Visual Cortex

2012
Nicotine enhances GABAergic inhibition of oxytocin mRNA-expressing neuron in the hypothalamic paraventricular nucleus in vitro in rats.
    Neuroscience letters, 2017, 01-18, Volume: 638

    Topics: Action Potentials; Animals; Excitatory Postsynaptic Potentials; GABA-A Receptor Antagonists; gamma-Aminobutyric Acid; Inhibitory Postsynaptic Potentials; Male; Neurons; Nicotine; Oxytocin; Paraventricular Hypothalamic Nucleus; Pyridazines; Rats, Wistar; RNA, Messenger; Tetrodotoxin

2017