Compounds > cyc 202
Page last updated: 2024-09-04

cyc 202 and on123300

cyc 202 has been researched along with on123300 in 1 studies

Compound Research Comparison

Studies
(cyc 202)		Trials
(cyc 202)		Recent Studies (post-2010)
(cyc 202)		Studies
(on123300)		Trials
(on123300)		Recent Studies (post-2010) (on123300)
9797393707

Protein Interaction Comparison

ProteinTaxonomycyc 202 (IC50)on123300 (IC50)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformHomo sapiens (human)0.144
NUAK family SNF1-like kinase 1Homo sapiens (human)0.0049
Cyclin-T1Homo sapiens (human)0.117
Tyrosine-protein kinase ABL1Homo sapiens (human)0.0533
Tyrosine-protein kinase FynHomo sapiens (human)0.011
Cyclin-dependent kinase 1Homo sapiens (human)0.6
Macrophage colony-stimulating factor 1 receptorHomo sapiens (human)0.01
Proto-oncogene tyrosine-protein kinase receptor RetHomo sapiens (human)0.0092
Platelet-derived growth factor receptor betaHomo sapiens (human)0.026
Fibroblast growth factor receptor 1Homo sapiens (human)0.026
Cyclin-dependent kinase 4Homo sapiens (human)0.0086
G2/mitotic-specific cyclin-B1Homo sapiens (human)0.6
Cyclin-A2Homo sapiens (human)0.107
G1/S-specific cyclin-D1Homo sapiens (human)0.0089
G1/S-specific cyclin-E1Homo sapiens (human)0.377
Cyclin-dependent kinase 2Homo sapiens (human)0.197
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)0.0122
Cyclin-dependent kinase 7Homo sapiens (human)6
Cyclin-dependent kinase 9Homo sapiens (human)0.117
Cyclin-HHomo sapiens (human)6
CDK-activating kinase assembly factor MAT1Homo sapiens (human)6
Cyclin-dependent kinase 6Homo sapiens (human)0.0098
Cyclin-dependent-like kinase 5 Homo sapiens (human)0.272
Cyclin-dependent kinase 5 activator 1Homo sapiens (human)0.272

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Akula, B; Athuluridivakar, S; Baker, SJ; Bharathi, EV; Billa, VK; Cosenza, SC; Mallireddigari, MR; Padgaonkar, A; Pallela, VR; Reddy, EP; Reddy, MV; Subbaiah, DR; Vasquez-Del Carpio, R1

Other Studies

1 other study(ies) available for cyc 202 and on123300

ArticleYear
Discovery of 8-cyclopentyl-2-[4-(4-methyl-piperazin-1-yl)-phenylamino]-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carbonitrile (7x) as a potent inhibitor of cyclin-dependent kinase 4 (CDK4) and AMPK-related kinase 5 (ARK5).
    Journal of medicinal chemistry, 2014, Feb-13, Volume: 57, Issue:3

    Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle; Cell Line, Tumor; Cyclin-Dependent Kinase 4; Drug Screening Assays, Antitumor; Female; Heterografts; Humans; Mice; Mice, Nude; Molecular Docking Simulation; Neoplasm Transplantation; Protein Kinases; Pyridines; Pyrimidines; Repressor Proteins; Structure-Activity Relationship

2014