Page last updated: 2024-09-05

biotin and paclitaxel

biotin has been researched along with paclitaxel in 25 studies

Compound Research Comparison

Studies
(biotin)
Trials
(biotin)
Recent Studies (post-2010)
(biotin)
Studies
(paclitaxel)
Trials
(paclitaxel)
Recent Studies (post-2010) (paclitaxel)
14,847953,88231,8745,72915,395

Protein Interaction Comparison

ProteinTaxonomybiotin (IC50)paclitaxel (IC50)
Integrin beta-3Homo sapiens (human)0.034
Integrin alpha-V Homo sapiens (human)0.034
ATP-dependent translocase ABCB1Homo sapiens (human)2.598
Botulinum neurotoxin type A Clostridium botulinum5.2
UDP-glucuronosyltransferase 2B7Homo sapiens (human)4.9
UDP-glucuronosyltransferase 1-6Homo sapiens (human)4.9
Substance-K receptorHomo sapiens (human)6.125
UDP-glucuronosyltransferase 1A1 Homo sapiens (human)4.9
UDP-glucuronosyltransferase 1A4Homo sapiens (human)4.9
UDP-glucuronosyltransferase 2B10 Homo sapiens (human)4.9
Delta-type opioid receptorHomo sapiens (human)4.202
Tyrosine-protein kinase MerHomo sapiens (human)4.9
Tubulin beta-3 chainHomo sapiens (human)0.0082
Beta-tubulin Leishmania donovani1
Nucleotide-binding oligomerization domain-containing protein 2Homo sapiens (human)7.9433
Solute carrier organic anion transporter family member 1B3Homo sapiens (human)0.26
Solute carrier organic anion transporter family member 1B1Homo sapiens (human)0.28

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (4.00)18.2507
2000's4 (16.00)29.6817
2010's14 (56.00)24.3611
2020's6 (24.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Cao, SL; Jiang, W; Li, J; Li, YS; Li, Z; Liao, J; Peng, B; Ren, TT; Wang, FC; Wang, G; Wang, H; Xu, S; Xu, X; Yang, CR1
Dubois, J; Guénard, D; Guéritte-Voegelein, F; Le Goff, MT; Tollon, Y; Wright, M1
Breipohl, W; Giessmann, D; Meller, K; Theiss, C1
Austin, DJ; Boehmerle, W; Ehrlich, BE; Johnston, DG; Lazarus, MB; McKenzie, KM; Splittgerber, U1
Florin, EL; Frey, E; Pampaloni, F; Taute, KM1
Ma, L; Panyam, J; Patil, Y; Sadhukha, T1
Ma, L; Panyam, J; Patil, YB; Sadhukha, T; Swaminathan, SK1
Gong, YC; Guo, L; Li, YP; Li, ZL; Xiong, XY1
Farah, MH; Ferraris, D; Griffin, JW; Hoffman, PN; Nguyen, T; Pan, BH; Price, DL; Slusher, BS; Tsukamoto, T; Wong, PC1
Bae, MS; Heo, DN; Kwon, IK; Lee, JB; Lee, SC; Lee, WJ; Moon, HJ; Sun, IC; Yang, DH1
Alves, NJ; Bilgicer, B; Champion, MM; Handlogten, MW; Kiziltepe, T; Moustakas, DT; Navari, RM; Shaw, BF; Shi, Y; Stefanick, JF1
Dráber, P; Dráberová, E; Hájková, Z; Stegurová, L; Sulimenko, V1
Feng, L; Li, J; Liu, F; Liu, Y; Yu, D; Zhang, N1
Aleandri, S; Bandera, D; Landau, EM; Mezzenga, R1
Bhatt, H; Biswas, S; Ghosh, B; Kumari, P; Rompicharla, SVK1
Li, Q; Liang, N; Sun, S; Yan, C; Yan, P1
Fu, Q; Guo, L; Huang, M; Peng, Y; Pu, Y; Wu, Y; Zheng, Y1
Beztsinna, N; Hennink, WE; Lammers, T; Shi, Y; van Nostrum, CF; van Steenbergen, MJ; Wang, Y1
Hai, L; Liu, Q; Lu, R; Wang, S; Wu, Y; Yang, C; Zhou, L1
Balan, V; Dodi, G; Mihai, CT; Rusu, AG; Ursachi, VC; Verestiuc, L1
Chen, X; Gong, YC; Li, ZL; Wang, QX; Xiong, XY1
Fens, MH; Heger, M; Hennink, WE; Lammers, T; Shi, Y; van Kronenburg, NCH; van Nostrum, CF; Wang, Y1

Other Studies

25 other study(ies) available for biotin and paclitaxel

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Synthesis, cytotoxic evaluation and target identification of thieno[2,3-d]pyrimidine derivatives with a dithiocarbamate side chain at C2 position.
    European journal of medicinal chemistry, 2018, Jun-25, Volume: 154

    Topics: Antineoplastic Agents; Cell Cycle; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Molecular Structure; Pyrimidines; Structure-Activity Relationship; Thiocarbamates; Tumor Cells, Cultured

2018
Fluorescent and biotinylated analogues of docetaxel: synthesis and biological evaluation.
    Bioorganic & medicinal chemistry, 1995, Volume: 3, Issue:10

    Topics: Animals; Antineoplastic Agents, Phytogenic; Avidin; Biotin; Brain Chemistry; Cattle; Cells, Cultured; Docetaxel; Fluorescent Dyes; Macropodidae; Magnetic Resonance Spectroscopy; Microtubules; Paclitaxel; Taxoids; Tubulin

1995
Decreased gap junctional communication in neurobiotin microinjected lens epithelial cells after taxol treatment.
    Anatomy and embryology, 2005, Volume: 209, Issue:5

    Topics: Actin Cytoskeleton; Animals; Antineoplastic Agents, Phytogenic; Biotin; Cattle; Cell Communication; Cell Membrane; Connexin 43; Down-Regulation; Epithelial Cells; Freeze Etching; Gap Junctions; Lens, Crystalline; Microinjections; Microscopy, Confocal; Microscopy, Electron, Transmission; Microtubules; Paclitaxel; Protein Transport

2005
Paclitaxel induces calcium oscillations via an inositol 1,4,5-trisphosphate receptor and neuronal calcium sensor 1-dependent mechanism.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Nov-28, Volume: 103, Issue:48

    Topics: Biotin; Calcium; Calcium Signaling; Cell Line, Tumor; Endoplasmic Reticulum; Humans; Inositol 1,4,5-Trisphosphate Receptors; Neuroblastoma; Neuronal Calcium-Sensor Proteins; Neuropeptides; Paclitaxel; RNA Interference

2006
Microtubule dynamics depart from the wormlike chain model.
    Physical review letters, 2008, Jan-18, Volume: 100, Issue:2

    Topics: Biotin; Microtubules; Models, Chemical; Paclitaxel; Rhodamines

2008
Nanoparticle-mediated simultaneous and targeted delivery of paclitaxel and tariquidar overcomes tumor drug resistance.
    Journal of controlled release : official journal of the Controlled Release Society, 2009, May-21, Volume: 136, Issue:1

    Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biotin; Cell Line, Tumor; Cell Survival; Drug Carriers; Drug Combinations; Drug Resistance, Neoplasm; Female; Humans; Lactic Acid; Leukemia, T-Cell; Mammary Neoplasms, Animal; Mice; Mice, Inbred BALB C; Nanoparticles; Neoplasm Transplantation; Paclitaxel; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Quinolines

2009
The use of nanoparticle-mediated targeted gene silencing and drug delivery to overcome tumor drug resistance.
    Biomaterials, 2010, Volume: 31, Issue:2

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biotin; Cell Death; Cell Line, Tumor; Drug Delivery Systems; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Gene Silencing; Humans; Mice; Nanoparticles; Paclitaxel; Particle Size; RNA, Small Interfering; Surface Properties

2010
Active targeting behaviors of biotinylated pluronic/poly(lactic acid) nanoparticles in vitro through three-step biotin-avidin interaction.
    Journal of biomaterials science. Polymer edition, 2011, Volume: 22, Issue:12

    Topics: Avidin; Biological Transport; Biotin; CA-125 Antigen; Cell Line, Tumor; Drug Delivery Systems; Fluorescent Dyes; Gene Expression Regulation, Neoplastic; Humans; Lactic Acid; Nanoparticles; Paclitaxel; Poloxalene; Polyesters; Polymers; Protein Binding

2011
Reduced BACE1 activity enhances clearance of myelin debris and regeneration of axons in the injured peripheral nervous system.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011, Apr-13, Volume: 31, Issue:15

    Topics: Acrylamide; Amyloid Precursor Protein Secretases; Animals; Antineoplastic Agents, Phytogenic; Aspartic Acid Endopeptidases; Axons; Biotin; Enzyme Inhibitors; Ganglia, Spinal; Immunohistochemistry; Infusion Pumps, Implantable; Mice; Mice, 129 Strain; Mice, Knockout; Microscopy, Electron; Myelin Sheath; Nerve Degeneration; Nerve Regeneration; Neuromuscular Junction; Paclitaxel; Peripheral Nervous System; Phagocytosis; Sciatic Nerve; Wallerian Degeneration

2011
Gold nanoparticles surface-functionalized with paclitaxel drug and biotin receptor as theranostic agents for cancer therapy.
    Biomaterials, 2012, Volume: 33, Issue:3

    Topics: Animals; beta-Cyclodextrins; Biotin; Cell Line, Tumor; Cell Survival; Flow Cytometry; Gold; HeLa Cells; Humans; Metal Nanoparticles; Mice; NIH 3T3 Cells; Paclitaxel; Receptors, Growth Factor

2012
Selective photocrosslinking of functional ligands to antibodies via the conserved nucleotide binding site.
    Biomaterials, 2013, Volume: 34, Issue:22

    Topics: Amino Acid Sequence; Animals; Antibodies; Antibodies, Monoclonal, Murine-Derived; Antigens; Binding Sites; Biotin; Blotting, Western; Buffers; Conserved Sequence; Cross-Linking Reagents; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Immunoglobulin G; Indoles; Ligands; Mass Spectrometry; Molecular Docking Simulation; Molecular Sequence Data; Nucleotides; Oligopeptides; Paclitaxel; Protein Binding; Receptors, Fc; Rituximab; Thermodynamics; Ultraviolet Rays

2013
Quantification of α-tubulin isotypes by sandwich ELISA with signal amplification through biotinyl-tyramide or immuno-PCR.
    Journal of immunological methods, 2013, Sep-30, Volume: 395, Issue:1-2

    Topics: Animals; Antibodies, Monoclonal; Biotin; Cell Line; Enzyme-Linked Immunosorbent Assay; Epitope Mapping; Mast Cells; Mice; Paclitaxel; Polymerase Chain Reaction; Protein Isoforms; Thapsigargin; Tubulin; Tyramine

2013
Theranostic Polymeric Micelles for the Diagnosis and Treatment of Hepatocellular Carcinoma.
    Journal of biomedical nanotechnology, 2015, Volume: 11, Issue:4

    Topics: alpha-Fetoproteins; Animals; Antibodies; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Avidin; Biotin; Biotinylation; Carcinoma, Hepatocellular; Gold; Hep G2 Cells; Humans; Lactates; Liver Neoplasms; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Metal Nanoparticles; Mice; Micelles; Neoplasm Transplantation; Paclitaxel; Pentetic Acid; Phototherapy; Polyesters; Polyethylene Glycols; Polymers; Singlet Oxygen

2015
Biotinylated Cubosomes: A Versatile Tool for Active Targeting and Codelivery of Paclitaxel and a Fluorescein-Based Lipid Dye.
    Langmuir : the ACS journal of surfaces and colloids, 2015, Nov-24, Volume: 31, Issue:46

    Topics: Biological Transport; Biotin; Cell Survival; Drug Carriers; Fluorescein; Fluorescent Dyes; HeLa Cells; Humans; Lipids; Liquid Crystals; Models, Molecular; Molecular Conformation; Nanoparticles; Paclitaxel

2015
Biotin functionalized PEGylated poly(amidoamine) dendrimer conjugate for active targeting of paclitaxel in cancer.
    International journal of pharmaceutics, 2019, Feb-25, Volume: 557

    Topics: A549 Cells; Antineoplastic Agents, Phytogenic; Biotin; Cell Survival; Dendrimers; Drug Carriers; Humans; Neoplasms; Paclitaxel; Polyethylene Glycols; Spheroids, Cellular; Tumor Cells, Cultured

2019
Biotin and arginine modified hydroxypropyl-β-cyclodextrin nanoparticles as novel drug delivery systems for paclitaxel.
    Carbohydrate polymers, 2019, Jul-15, Volume: 216

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Animals; Antineoplastic Agents; Arginine; Biotin; Carcinoma; Drug Carriers; Female; Humans; MCF-7 Cells; Mice; Nanoparticles; Paclitaxel; Particle Size; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays

2019
Biotin and glucose dual-targeting, ligand-modified liposomes promote breast tumor-specific drug delivery.
    Bioorganic & medicinal chemistry letters, 2020, 06-15, Volume: 30, Issue:12

    Topics: Animals; Antineoplastic Agents, Phytogenic; Biotin; Breast Neoplasms; Cell Line, Tumor; Dose-Response Relationship, Drug; Drug Carriers; Drug Delivery Systems; Female; Glucose; Humans; Ligands; Liposomes; Mammary Neoplasms, Experimental; Mice; Molecular Structure; Paclitaxel; Structure-Activity Relationship

2020
Biotin-decorated all-HPMA polymeric micelles for paclitaxel delivery.
    Journal of controlled release : official journal of the Controlled Release Society, 2020, 12-10, Volume: 328

    Topics: Biotin; Drug Carriers; Drug Delivery Systems; HEK293 Cells; Humans; Methacrylates; Micelles; Paclitaxel; Polyethylene Glycols; Polymers

2020
Biotin and glucose co-modified multi-targeting liposomes for efficient delivery of chemotherapeutics for the treatment of glioma.
    Bioorganic & medicinal chemistry, 2021, 01-01, Volume: 29

    Topics: Animals; Antineoplastic Agents, Phytogenic; Biotin; Blood-Brain Barrier; Brain Neoplasms; Dose-Response Relationship, Drug; Drug Carriers; Drug Delivery Systems; Glioma; Glucose; Ligands; Liposomes; Male; Mice; Mice, Inbred Strains; Molecular Structure; Paclitaxel; Structure-Activity Relationship; Tumor Cells, Cultured

2021
Paclitaxel-Loaded Magnetic Nanoparticles Based on Biotinylated
    Molecules (Basel, Switzerland), 2021, Jun-07, Volume: 26, Issue:11

    Topics: Antineoplastic Agents, Phytogenic; Biotin; Cell Line, Tumor; Chitosan; Colloids; Delayed-Action Preparations; Drug Carriers; Drug Delivery Systems; Humans; Hydrophobic and Hydrophilic Interactions; Magnetite Nanoparticles; MCF-7 Cells; Paclitaxel; Polymers

2021
Transferrin/folate dual-targeting Pluronic F127/poly(lactic acid) polymersomes for effective anticancer drug delivery.
    Journal of biomaterials science. Polymer edition, 2022, Volume: 33, Issue:9

    Topics: Antineoplastic Agents; Biotin; Cell Line, Tumor; Drug Carriers; Drug Delivery Systems; Folic Acid; Nanoparticles; Paclitaxel; Poloxamer; Polyesters; Transferrin

2022
Magnetic beads for the evaluation of drug release from biotinylated polymeric micelles in biological media.
    Journal of controlled release : official journal of the Controlled Release Society, 2022, Volume: 349

    Topics: Animals; Biotin; Curcumin; Cytostatic Agents; Drug Carriers; Drug Delivery Systems; Drug Liberation; Magnetic Phenomena; Mice; Micelles; Paclitaxel; Particle Size; Polyethylene Glycols; Polymers; Polysorbates; Reproducibility of Results; Serum Albumin, Bovine; Solvents; Streptavidin

2022