Page last updated: 2024-11-12
xestoaminol c
Description
xestoaminol C: a metabolite of Fiji sponge, Xestospongia sp.; structure in first source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]
1-deoxytetradecasphinganine : A sphingoid that is tetradecasphinganine in which the terminal hydroxy group has been replaced by a hydrogen. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]
Cross-References
Synonyms (13)
Synonym |
LMSP01080033 |
xestoaminol c |
1-deoxy-tetradecasphinganine |
CHEMBL448146 |
(2s,3r)-xestoaminol c |
chebi:73882 , |
(2s,3r)-2-aminotetradecan-3-ol |
1-deoxytetradecasphinganine |
WMUMHAZHWIUBPN-UONOGXRCSA-N |
(2s,3r)-2-amino-3-tetradecanol |
SCHEMBL5271731 |
Q27144207 |
DTXSID001025435 |
Roles (1)
Role | Description |
metabolite | Any intermediate or product resulting from metabolism. The term 'metabolite' subsumes the classes commonly known as primary and secondary metabolites. |
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Drug Classes (2)
Class | Description |
sphingoid | Sphinganine, its homologs and stereoisomers, and the hydroxy and unsaturated derivatives of these compounds. |
amino alcohol | An alcohol containing an amino functional group in addition to the alcohol-defining hydroxy group. |
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res] |
Bioassays (4)
Assay ID | Title | Year | Journal | Article |
AID623346 | Cytotoxicity against human SHG44 at 50 uM after 24 hrs by cell counting kit-8 assay | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11
| Diastereoselective synthesis and bioactivity of long-chain anti-2-amino-3-alkanols. |
AID623348 | Antiproliferative activity against human SHG44 cells after 24 hrs by cell counting kit-8 assay | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11
| Diastereoselective synthesis and bioactivity of long-chain anti-2-amino-3-alkanols. |
AID336239 | Inhibition of reverse transcriptase at 1 mg/ml | | | |
AID623347 | Growth inhibition of human SHG44 at 10 uM after 24 hrs by cell counting kit-8 assay | 2011 | European journal of medicinal chemistry, Nov, Volume: 46, Issue:11
| Diastereoselective synthesis and bioactivity of long-chain anti-2-amino-3-alkanols. |
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Research
Studies (6)
Timeframe | Studies, This Drug (%) | All Drugs % |
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 3 (50.00) | 29.6817 |
2010's | 3 (50.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |
Market Indicators
Research Demand Index: 19.92
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
Metric | This Compound (vs All) |
---|
Research Demand Index | 19.92 (24.57) | Research Supply Index | 2.08 (2.92) | Research Growth Index | 4.37 (4.65) | Search Engine Demand Index | 15.26 (26.88) | Search Engine Supply Index | 2.00 (0.95) |
| |
Study Types
Publication Type | This drug (%) | All Drugs (%) |
Trials | 0 (0.00%) | 5.53% |
Reviews | 0 (0.00%) | 6.00% |
Case Studies | 0 (0.00%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 7 (100.00%) | 84.16% |
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] |