Page last updated: 2024-12-07

widdrol

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Cross-References

ID SourceID
PubMed CID94334
CHEMBL ID2253133
SCHEMBL ID6519819
MeSH IDM0210792

Synonyms (7)

Synonym
widdrol
6892-80-4
(7s,9as)-4,4,7,9a-tetramethyl-1,2,3,6,8,9-hexahydrobenzo[7]annulen-7-ol
1h-benzocyclohepten-7-ol, 2,3,4,4a,5,6,7,8-octahydro-1,1,4a,7-tetramethyl-, (4as-cis)-
CHEMBL2253133
SCHEMBL6519819
DTXSID50988627

Research Excerpts

Overview

Widdrol is an odorous compound derived from Juniperus chinensis. It is widely used in traditional medicine to treat fever, inflammation and cancer.

ExcerptReferenceRelevance
"Widdrol is an odorous compound derived from Juniperus chinensis that is widely used in traditional medicine to treat fever, inflammation and cancer. "( Widdrol, a sesquiterpene isolated from Juniperus chinensis, inhibits angiogenesis by targeting vascular endothelial growth factor receptor 2 signaling.
Jeong, HY; Jin, S; Kim, BW; Kwon, HJ; Oh, YN; Park, HJ; Yun, HJ; Yun, SG, 2015
)
3.3
"Widdrol is an odorant compound isolated from Juniperus chinensis. "( Widdrol activates DNA damage checkpoint through the signaling Chk2-p53-Cdc25A-p21-MCM4 pathway in HT29 cells.
Hyun, SK; Kim, BW; Kwon, HJ; Park, JH; Yun, HJ, 2012
)
3.26
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (3)

Assay IDTitleYearJournalArticle
AID1090521Antifungal activity against Colletotrichum gloeosporioides 20122 assessed as inhibition of mycelial growth at => 100 ppm measured after 24 to 144 hr2006Journal of agricultural and food chemistry, Oct-04, Volume: 54, Issue:20
The antifungal activity of widdrol and its biotransformation by Colletotrichum gloeosporioides (penz.) Penz. & Sacc. and Botrytis cinerea Pers.: Fr.
AID1090520Antifungal activity against Botryotinia fuckeliana 2100 assessed as inhibition of mycelial growth at 100 ppm measured after 6 days2006Journal of agricultural and food chemistry, Oct-04, Volume: 54, Issue:20
The antifungal activity of widdrol and its biotransformation by Colletotrichum gloeosporioides (penz.) Penz. & Sacc. and Botrytis cinerea Pers.: Fr.
AID1090519Antifungal activity against Botryotinia fuckeliana 2100 assessed as inhibition of mycelial growth at 200 ppm measured after 6 days2006Journal of agricultural and food chemistry, Oct-04, Volume: 54, Issue:20
The antifungal activity of widdrol and its biotransformation by Colletotrichum gloeosporioides (penz.) Penz. & Sacc. and Botrytis cinerea Pers.: Fr.
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (9)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (11.11)18.7374
1990's1 (11.11)18.2507
2000's1 (11.11)29.6817
2010's6 (66.67)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 30.32

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index30.32 (24.57)
Research Supply Index2.30 (2.92)
Research Growth Index4.95 (4.65)
Search Engine Demand Index27.81 (26.88)
Search Engine Supply Index1.75 (0.95)

This Compound (30.32)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other9 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]