Page last updated: 2024-12-07
widdrol
Description
Research Excerpts
Clinical Trials
Roles
Classes
Pathways
Study Profile
Bioassays
Related Drugs
Related Conditions
Protein Interactions
Research Growth
Market Indicators
Cross-References
| ID Source | ID |
|---|---|
| PubMed CID | 94334 |
| CHEMBL ID | 2253133 |
| SCHEMBL ID | 6519819 |
| MeSH ID | M0210792 |
Synonyms (7)
| Synonym |
|---|
| widdrol |
| 6892-80-4 |
| (7s,9as)-4,4,7,9a-tetramethyl-1,2,3,6,8,9-hexahydrobenzo[7]annulen-7-ol |
| 1h-benzocyclohepten-7-ol, 2,3,4,4a,5,6,7,8-octahydro-1,1,4a,7-tetramethyl-, (4as-cis)- |
| CHEMBL2253133 |
| SCHEMBL6519819 |
| DTXSID50988627 |
Research Excerpts
Overview
Widdrol is an odorous compound derived from Juniperus chinensis. It is widely used in traditional medicine to treat fever, inflammation and cancer.
| Excerpt | Reference | Relevance |
|---|---|---|
| "Widdrol is an odorous compound derived from Juniperus chinensis that is widely used in traditional medicine to treat fever, inflammation and cancer. " | ( Widdrol, a sesquiterpene isolated from Juniperus chinensis, inhibits angiogenesis by targeting vascular endothelial growth factor receptor 2 signaling. Jeong, HY; Jin, S; Kim, BW; Kwon, HJ; Oh, YN; Park, HJ; Yun, HJ; Yun, SG, 2015) | 3.3 |
| "Widdrol is an odorant compound isolated from Juniperus chinensis. " | ( Widdrol activates DNA damage checkpoint through the signaling Chk2-p53-Cdc25A-p21-MCM4 pathway in HT29 cells. Hyun, SK; Kim, BW; Kwon, HJ; Park, JH; Yun, HJ, 2012) | 3.26 |
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
Bioassays (3)
| Assay ID | Title | Year | Journal | Article |
|---|---|---|---|---|
| AID1090521 | Antifungal activity against Colletotrichum gloeosporioides 20122 assessed as inhibition of mycelial growth at => 100 ppm measured after 24 to 144 hr | 2006 | Journal of agricultural and food chemistry, Oct-04, Volume: 54, Issue:20 | The antifungal activity of widdrol and its biotransformation by Colletotrichum gloeosporioides (penz.) Penz. & Sacc. and Botrytis cinerea Pers.: Fr. |
| AID1090520 | Antifungal activity against Botryotinia fuckeliana 2100 assessed as inhibition of mycelial growth at 100 ppm measured after 6 days | 2006 | Journal of agricultural and food chemistry, Oct-04, Volume: 54, Issue:20 | The antifungal activity of widdrol and its biotransformation by Colletotrichum gloeosporioides (penz.) Penz. & Sacc. and Botrytis cinerea Pers.: Fr. |
| AID1090519 | Antifungal activity against Botryotinia fuckeliana 2100 assessed as inhibition of mycelial growth at 200 ppm measured after 6 days | 2006 | Journal of agricultural and food chemistry, Oct-04, Volume: 54, Issue:20 | The antifungal activity of widdrol and its biotransformation by Colletotrichum gloeosporioides (penz.) Penz. & Sacc. and Botrytis cinerea Pers.: Fr. |
| [information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||||
Research
Studies (9)
| Timeframe | Studies, This Drug (%) | All Drugs % |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 1 (11.11) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 6 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||
Market Indicators
Research Demand Index: 30.32
According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be moderate demand-to-supply ratio for research on this compound.
| This Compound (30.32) All Compounds (24.57) |
Study Types
| Publication Type | This drug (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 0 (0.00%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 9 (100.00%) | 84.16% |
| [information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023] | ||